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The Results of Extracardiac Fontan Operation in the Patients with Heterotaxy Syndrome (이소성증후군에서의 심장외도관 폰탄 수술의 결과)

  • Lim Hong Gook;Kim Soo-Jin;Lee Chang-Ha;Kim Woong-Han;Hwang Seong Wook;Lee Cheul;Oh Sam-Sae;Baek Man-Jong;Na Chan-Young;Kim Jae Hyun;Seo Hong Joo;Jung Sung Chol;Kim Chong Whan
    • Journal of Chest Surgery
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    • v.38 no.8 s.253
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    • pp.529-537
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    • 2005
  • Background: Historically the Fontan operation in patients with single ventricle and heterotaxy syndrome has been associated with high mortality because of systemic or pulmonary anomalous venous drainage, incompetent common atrioventricular valve, right ventricle type univentricular heart, and arrhythmia. Material and Method: A retrospective review of 62 patients $(age:\;54.79\pm33.97\;months)$ with heterotaxy syndrome who underwent a extracadiac Fontan operation between 1996 and 2005 was performed. Twenty one patients had left atrial isomerism, and 41 had right isomerism. The Fontan procedure was staged in all but 2 patients, and a fenestration was less placed in left isomerism. Result: Left isomerism was associated more with interrupted inferior vena cava and pulmonary arteriovenous fistula, and right isomerism was associated more with anomalous pulmonary venous drainage, common atrioventricular valve and morphologic right ventricle. There were 3 hospital deaths$(4.8\%)$ and 3 late deaths $(5.2\%)$ with a follow-up duration of $48.8\pm31.0$ months. Eight-year survivals were $90.5\pm6.4\%$ in left isomerism and $88.6\pm5.4\%$ in right isomerism (p=0.94). At 8 years, freedom from reoperation was $73.9\pm11.3\%$ in left isomerism, and $82.3\pm6.7\%$ in right isomerism (p=0.87). Atrioventricular valve regurgitation progressed after Fontan operation in heterotaxy syndrome, and reoperation for pulmonary arteriovenous fistula and permanent pacemaker implantation for sinus node dysfunction were required more in left isomerism. Conclusion: The extracardiac Fontan operation can now be performed in patients with heterotaxy syndrome with excellent survival. However, morbidity in terms of postoperative atrioventricular valve regurgitation, arrhythmia, and pulmonary arteriovenous fistula remains significant.

Development of Central Nervous System in Scuttle Fly (Scuttle Fly에서 중추신경계 발달 연구)

  • Park, Ho-Hyun;Park, Mi-Suk;Na, Kil-Ju
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.3
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    • pp.284-288
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    • 2018
  • The scuttle fly central nervous system (CNS) is unobservable during egg and larvae instar stage 1. During days 2~3 of larvae instar stage 2, the left and right hemisphere of the brain can be observed. Below the brain, the subesophageal ganglion (SOG) connects to the ventral nerve cord (VNC). During days 3~5 of larvae instar stage 3, the CNS enlarged slightly with no other changes. During days 1~3 of the pupal stage the CNS moved to the head with no distinguishable changes from the previous stage. During days 4~6 of the pupal stage, the left and right hemisphere of the brain had fused into one mass and the optic lobe (OL) located on the side of the brain completed its development. During days 7~9 of the pupal stage, the OL began to show eyeball pigment. The SOG was connected to the brain and the VNC began to separate, which was accompanied by an increase in nerve fibers. During days 10~12 of the pupal stage, the brain of the CNS and VNC was clearly distinguished and the brown pigmentation of OL became darker. During days 13~15 days of the pupal stage, the separated brain and VNC became connected by thin nerve fiber. The VNC began to separate into two with a greater increase in nerve fibers. The adult fly showed similar features to the previous stage, but the brain was located in the head and the VNC in the chest.

Estimation of Hi-pass Traffic Dispersion Rates to Determine The Optimal Location of Hi-pass Lanes at A Toll Plaza (요금소 하이패스 차로 배치 최적화를 위한 하이패스 차량 교통분산율 추정)

  • Lee, Jaesoo;Lee, Ki-Young;Lee, Cheol-Ki;Yun, Ilsoo;Yu, Jeong Whon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.12 no.4
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    • pp.22-32
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    • 2013
  • Since the percentage of vehicles equipped with Hi-pass, an electronic toll collecting device, has increased rapidly, it is very crucial to determine the optimal location of Hi-pass lanes at a toll plaza in terms of traffic control and operation. In this study, the appropriateness of existing Hi-pass lanes of a toll plaza is evaluated considering its physical geometry and traffic characteristics. A new evaluating criterion called "traffic dispersion rate" is developed in order to measure the level of traffic spreading across the toll booth lanes at a toll plaza. Logistic regression models are constructed to estimate the relationship between the traffic dispersion rate and its affecting variables. The model estimation results show that several variables including Hi-pass lane traffic volume, length of toll plaza, entering/exiting taper lengths, and locations of Hi-pass lanes. The results also suggest that traffic dispersion rate can be increased by adjusting the location of Hi-pass lanes. The study enables us to quantify traffic dispersion rate which can be used to optimize the location and operation of Hi-pass lanes at toll plazas.

Strains of abutment and bones on implant overdentures (임플란트 피개의치에서 지대주와 골의 변형률에 관한 연구)

  • Kim, Myung-Seok;Heo, Seong-Joo;Koak, Jai-Young;Kim, Sung-Kyun
    • The Journal of Korean Academy of Prosthodontics
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    • v.47 no.2
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    • pp.222-231
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    • 2009
  • Statements of the problem: Over the past decades, conventional complete dentures were used for various patients although they have incomplete function. Overdentures using dental implants could help the improvement of denture function. Purpose: The purpose of this study was to compare the strains of abutment and bone on implant overdenture between splinted and unsplinted type of prosthesis. Additionally, the strain values of parallel placed implant model and unparallel placed implant model were compared. Material and methods: Two acrylic resin model were prepared and two implants were placed at the canine positions in each model. In the first model, two implant were placed parallel. In the second model, two implants were placed with 10 degree labiolingual divergence. Two types of abutment were connected to the fixtures alternatively. One was splint type of Hader bar, the other was unsplint type of ball abutment. Overdentures were fabricated with corresponding attachment systems and seated on abutments. Strains of abutments and labial bone simulants were measured with electric resistance strain gauges when static load from 100 N to 200 N were applied to overdentures. Results: 1. Splinted type of overdentures using bar and clip showed higher absolute strain values. But the strain was compressive and the load was shared by two implants(P<.05). 2. Unsplinted type overdentures using ball and O-ring showed low absolute strain values(P<.05). 3. Labially inclined implant showed higher tensile strain values in unsplinted type of prosthesis than in splinted type of prosthesis. Lingually inclined implant showed rather low strain values under load(P<.05). 4. Non parallel implant model showed higher absolute strain values than parallel placed implant model comprehensively(P<.05).

A Review of Spatial Neglect: Types, Theories, Neuroanatomy, Assessments and Treatment (편측 공간무시에 관한 고찰: 유형 및 이론, 해부학적 영역, 평가와 치료)

  • Jeong, Eun-Hwa
    • Therapeutic Science for Rehabilitation
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    • v.6 no.1
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    • pp.11-23
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    • 2017
  • Spatial neglect is a neurological disorder following stroke, a lesion that usually affects the right hemisphere, fail to process or attention on the contralateral side of body and space. Functional neuroimaging studies report that spatial neglect is associated with lesions of large middle cerebral artery, perisylvian network and attention network. Spatial neglect is associated with a poor outcome. For optimal diagnosis and intervention, Types and theories of spatial neglect should be considered, in addition to clinical assessment with the conventional test and functional test. The treatment for spatial neglect could be consist of top-down approaches and bottom-up approaches. Recent trends in rehabilitation intervention for spatial neglect have reported prism adaptation.

Pulmonary Vessels Segmentation and Refinement On the Chest CT Images (흉부 CT 영상에서 폐 혈관 분할 및 정제)

  • Kim, Jung-Chul;Cho, Joon-Ho;Hwang, Hyung-Soo
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.11
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    • pp.188-194
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    • 2013
  • In this paper, we proposed a new method for pulmonary vessels image segmentation and refinement from pulmonary image. Proposed method consist of following five steps. First, threshold estimation is performed by polynomial regression analysis of histogram variation rate of the pulmonary image. Second, segmentation of pulmonary vessels object is performed by density-based segmentation method based on estimated threshold in first step. Third, 2D connected component labeling method is applied to segmented pulmonary vessels. The seed point of both side diaphragms is determined by eccentricity and size of component. Fourth step is diaphragm extraction by 3D region growing method at the determined seed point. Finally, noise cancelation of pulmonary vessels image is performed by 3D connected component labeling method. The experimental result is showed accurately pulmonary vessels image segmentation, the diaphragm extraction and the noise cancelation of the pulmonary vessels image.

Changes of Serum IgM, IgG in Pig's Xenograft Perfusion and Immunofluorescence Changes of the Deposition of IgM, IgG in the Xenograft in Dogs (잡종견에서 돼지 신장과 폐를 이용한 혈액관류에서 수술 전.후 혈액의 IgM, IgG와 이식 장기의 IgM, IgG 침착 정도 변화)

  • Lee, Doo-Yun;Paik, Hyo-Chae;Jeon, Se-Eun;Kim, Eun-Young;Nam, Jin-Young;Hong, Soon-Won;Hwang, Jung-Joo;Wada, Hiromi;Bando, Toru
    • Journal of Chest Surgery
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    • v.40 no.7 s.276
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    • pp.467-472
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    • 2007
  • Background: Lung transplantation is the definitive therapy for end stage lung disorders. The success of allogenic lung transplantation has led to an increasing shortage of donor lungs from humans, including cadavers, and attention has now turned to transplantation of lungs from other species. However, there are many biological hurdles when using organs from other species because of hyperacute rejection after discordant xenotransplantation. Material and Method: Pigs (n=6, weighing $20{\sim}30kg$ each) for the donors and mongrel dogs (n=6, weighing $20{\sim}28kg$ each) for the recipients were used in this experiment. The left kidney of a pig was perfused to a mongrel dog for 30 minutes through the femoral artery and vein of the dog, and the right kidney was perfused for 30 minutes sequentially. Then, both lungs of the pig were perfused to the dog through the pulmonary artery and left atrium with using the same time intervals. The levels of IgM and IgG were measured from the blood and specimens of the kidney and lung. Result: The average levels of serum IgM gradually decreased after the perfusion, but the average levels of serum IgG did not charge from before to after perfusion. The immunohistochemical findings revealed decreased deposition of IgG and IgM after the perfusion. Conclusion: We conclude that the levels of the serum natural antibodies would be decreased with pre-transplantation xenograft perfusion in the recipient and the occurrence rate of hyperacute rejection after transplantation would be decreased.

A Design of Book Search program based on the Semantic Web (시맨틱 웹 기반의 도서검색 프로그램 설계)

  • Choi, Jun-nyeong;Lee, Ji-hun;Jung, In-jung;Yu, Don-hui
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.130-131
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    • 2014
  • 시맨틱 웹은 1998년 웹의 창시자인 Tim Berners Lee가 제안을 한 웹 기술로써 인간의 언어를 이해하고 인간과 쉽게 의사소통이 가능한 네트워크를 말한다. 즉 컴퓨터 스스로 웹에 연결된 정보의 의미를 인식하고 사용자가 필요로 하는 정보를 검색하며 검색된 정보에서 지식을 유추할 수 있는 기능을 제공하는 지능형 웹 환경이다. 이런 시맨틱 웹 개념을 적용한 사례로는 네이버 시맨틱 웹 영화검색 이있다. 본 논문에서는 네이버 시맨틱 웹 영화검색 시스템을 벤치마킹한 도서검색 서비스 설계를 제안하고자 한다. 본 도서검색 서비스는 온톨로지 개념을 적용하여 도서와 관련된 검색 카테고리를 설정하며, 간단한 시나리오는 다음과 같다. 한 권의 책을 검색하면 해당 책과 연관된 첫 번째 카테고리로 출판사, 제작한 년도, 저자, 장르, 관련 검색 도서 등의 데이터들이 상단에 제시된다. 제시된 카테고리에서 임의의 항목을 선택하면 그 하단 공백에 선택된 항목과 연관된 카테고리에 해당하는 항목들이 제시된다. 예를 들어, 출판사를 선택한다면 해당 출판사에서 출간된 도서들이 하단 공백에 열거가 되고 상단 두 번째 카테고리에 원작국가, 저자 관련 책, 수상정보, 공동 집필자, 책을 원작으로 확장된 컨텐츠 등 또 다른 카테고리가 우측으로 생성이 되며 선택을 할 수 있게 된다. 본 논문에서 제안하는 시맨틱 웹 기반 도서검색 서비스는 사용자가 검색하고자 하는 정보를 보다 효율적이고 사용자 중심에서 제공할 수 있다고 사료된다.

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Array of Ultrasonic Sensor for Obstacle Avoidance of Intelligent Wheelchair (지능형 휠체어의 장애물 감지를 위한 초음파 센서의 배열)

  • Kim, Tae-Ui;Kwon, Kyung-Su;Park, Se-Hyun
    • Proceedings of the Korea Information Processing Society Conference
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    • 2009.04a
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    • pp.15-18
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    • 2009
  • 지능형 휠체어 구현에 있어 초음파 센서의 배열은 전동휠체어가 장애물을 감지할 수 있는 능력을 결정한다. 따라서 본 논문에서는 지능형 휠체어의 장애물 감지를 위한 초음파 센서의 효과적인 배열 방법을 제안한다. 초음파 센서 모듈은 총 10개의 4개 세트로 구성되어 있다. 전동 휠체어의 전방, 좌, 우측에는 각각 3개의 센서를 48도씩 중첩되게 겹쳐 하나의 세트로 구성하고, 후방에는 하나의 센서를 구성한다. 지능형 휠체어는 사용자 인터페이스, 장애물 회피 모듈, 모터 제어 모듈, 초음파 센서 모듈로 구성된다. 사용자 인터페이스는 정해진 명령을 하달 받고, 모터 제어 모듈은 하달된 명령과 센서들에 의해 반환된 장애물과의 거리 정보로 모터제어보드에 연결되어 있는 두 개의 좌우 모터들을 조종한다. 센서 모듈은 전동휠체어가 움직이는 동안에 주기적으로 센서들로부터 거리 값을 반환 받아 벽 또는 장애물을 감지하여 장애물의 위치를 사용자 인터페이스를 통해서 알려 주고, 또한 장애물 회피 모듈에 의해 장애물을 우회 하도록 움직인다. 제안된 방법의 센서 배열은 실험을 통해 지능형 휠체어가 임의로 설치된 장애물을 효과적으로 감지하고 보다 정확하게 장애물을 회피 할 수 있음을 보였다.

Outcome of the Modified Norwood Procedure: 7 Years of Experience from a Single Institution (변형된 노우드(Norwood) 수술의 결과: 단일병원의 지난 7년간의 경험)

  • Kim, Hyung-Tae;Sung, Si-Chan;Kim, Si-Ho;Bae, Mi-Ju;Lee, Hyoung-Doo;Park, Ji-Ae;Chang, Yun-Hee
    • Journal of Chest Surgery
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    • v.43 no.4
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    • pp.364-374
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    • 2010
  • Background: We assessed the early and mid-term results of the modified Norwood procedure for first-stage palliation of hypoplastic left heart syndrome (HLHS) and its variants to identify the risk factors for hospital mortality. Material and Method: Between March, 2003, and December, 2009, 23 patients (18 males and 5 females) with HLHS or variants underwent the modified Norwood procedure. The age at operation ranged from 3 to 60 days (mean, $11.7{\pm}13.2days$) and weight at operation ranged from 2.2 to 4.8 kg (mean, $3.17{\pm}0.52kg$). We used a modified technique that spared the anterior wall of the main pulmonary artery in 20 patients. The sources of pulmonary blood flow were RV-PA conduit in 15 patients (group I) and RMBTS in 8 (group II). Follow-up was completed in 19 patients (19/20, 95%) in our hospital (mean $26.0{\pm}22.8months$). Result: Early death occurred in 3 patients (3/23, 13%), of whom 2 had TAPVC. Fourteen patients underwent subsequent bidirectional cavopulmonary connection (BCPC, stage 2) and seven underwent the Fontan operation (stage 3). Three patients died between stages, 2 before stage 2 and one before stage 3. The estimated 1-year and 5-year survival rates were 78% and 69%, respectively. On multivariate regression analysis, aberrant right subclavian artery (RSCA) and associated total anomalous pulmonary venous connection (TAPVC) were risk factors for hospital mortality after stage 1 Norwood procedure. Conclusion: HLHS and its variants can be palliated by the modified Norwood procedure with low operative mortality. Total anomalous pulmonary venous connection adversely affects the survival after a stage 1 Norwood procedure, and interstage mortality rates need to be improved.