• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.312-317
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• 2006

지역규모의 기후변화 모의결과를 이용하여 금강유역 용담댐의 홍수기 치수안전도에 대한 민감도분석을 수행하였다. 기후변화 모의에 사용된 SNURCM(Seoul National University Regional Climate Model)은 미국 National Center for Atmospheric Research의 Community Climate System Model의 전지구모형을 기반으로 spectral nudging 기법을 사용한 공간해상도 30 km, 연직 21층의 지역기후모형이다. 기후변화 시나리오로는 SRES 'B1'이 사용되었으며 과거 control run에 대한 기후모의 정확도 분석을 통하여 SNURCM 기상자료를 관측치와 비교한 결과 면적강우량을 다소 과소추정하였고 이점을 감안하여 SNURCM의 일 모의결과에 보정 계수를 적용하였다. 하천유출량은 SSARR 모형을 이용하여 SNURCM 모의가 수행된 전체기간을 $1980{\sim}1999$년과 $2000{\sim}2019$년으로 20년씩 나누어 용담댐 일 유입량을 산정하여 통계분석을 실시하였고 과거와 미래 20년 동안을 비교하여 본 결과 (1) 유량의 평균보다는 분산이 미래 20년 동안 증가하여 가뭄과 홍수에 대한 위험도가 증가함을 알 수 있었고, (2) 특히 연최대유량 또한 미래 20년 동안 상당히 증가하여 홍수기 치수대책이 더욱 중요해질 것으로 판단되었다. 마지막으로 용담댐 운영은 범용 시스템분석 도구인 STELLA(System Thinking Experimental Learning Laboratory with Animation) 상에서 GUI로 구현하여 유입량 변화에 따른 용담댐 치수안전도 변화를 모의해 보았다. 용담댐의 홍수기 운영은 저수지 수위가 제한수위를 초과하기 시작하면 Rigid ROM 발효하여 방류량을 결정하도록 구성하였고, 무효방류(spill)가 일어나는 현상을 실패로 가정하여 이에 대한 신뢰도(reliability), 회복도(resiliency), 그리고 심도(vulnerability)를 치수안전도 지표로 계산하였다. 전체기간을 1980년${\sim}$1999년, 2000년${\sim}$2019년, 2000년${\sim}$2009년, 그리고 2010년${\sim}$2019년까지 총 4구간으로 나누어 결과를 도출하였으며 예상한 바와 같이 후반기 20년 동안에 세 가지 지표가 취약해 지는 것을 확인할 수 있었고, 특히 2000년부터 2009년까지 10년 동안에는 더욱 취약해짐을 확인할 수 있었다.

• The Bimonthly Magazine for Agrochemicals and Plant Protection
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• v.12 no.1 s.100
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• pp.61-64
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• 1991

• Journal of Life Science
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• v.29 no.6
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• pp.735-739
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• 2019

The dried rhizomes and roots of Gentiana scabra (GS) have been frequently prescribed as a traditional folk medicine in East Asia (including China, Japan, and Korea) for the treatment of various pathophy-siological conditions, such as inflammatory skin diseases, anorexia, indigestion, gastric infections, and diabetes mellitus. In the present study, the effects of aqueous (GS-W) and ethanolic (GS-E) extracts of GS on gastrointestinal (GI) motor function were investigated by measuring the in vivo gastric emptying rate (GER) and the intestinal transit rate (ITR) in mice. The GER was significantly increased by GS-W at a dose of 1 g/kg. The ITR was significantly increased by GS-W (at doses of 0.1 and 1 g/kg) or GS-E (at a dose of 1 g/kg) in a dose-dependent manner. Furthermore, the ITR value of GS-W (at a dose of 1 g/kg) appeared to be higher than that of cisapride, which was the most prominent prokinetic agent in the 1900s but was removed from the market in 2000 due to its fatal side effects. The above results suggest that GS-W might be a potential prokinetic agent to replace cisapride.

• Korean Journal of Plant Resources
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• v.13 no.1
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• pp.66-79
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• 2000

Anatomical characters such as stem, leaf, ovary, calyx lobe, ultrastructure of stigma, epidermis of leaf blade and midvein, corolla lobe, nectary, seed coat and pollen were examined on 6 taxa of Korean Ophelia, including 5 taxa distributed in south Korea and one taxon considered to be the variation type of Ophelia wilfordi, in order to clarify the limits of intersection and interspecies and to establish the taxonomic position. One taxon distributed in north Korea was also included in the description of species by observation of herbarium specimen of the University of Tokyo in Japan. The two sections were successfully distinguished by internal structure of ovary, morphology of nectary, surface sculpturing of corolla lobe and pollen, ultrastructure of seed and seed coat, which were useful characters to distinguish taxa higher than species. The variation type of Ophelia wilfordi was not distinguished with other species except for absent or present of purple spot in corolla lobe.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.1
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• pp.9-14
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• 2018

In order to find new functional materials for the cosmetics application, we investigated the anti-oxidant and anti-melanogenic properties of Gentiana scabra extracts (GSE), which were prepared by the various extraction methods. Results showed that GSE had high DPPH radical scavenging activity in a dose-dependent manner. Also, GSE inhibited the prodution of melanin in B16F10 melanoma cell as well as tyrosinase activity. We also found that GSE inhibited mRNA expression of tyrosinase-related protein (TRP)-1 and 2. In conclusion we suggest that GSE is applicable to cosmetics as a potential ingredient for their anti-oxidant and whitening effects.

• Korean Journal of Plant Resources
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• v.12 no.4
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• pp.324-339
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• 1999

Morphological reinvestigation, external characters and discriminant functional analysis(44 qualitative characters) were examined on 6 taxa of Korean Ophelia, including 5 taxa distributed in south Korea, and one taxon considered to be the variation type of Ophelia wilfordi in order to clarify the limit of intersection and interspecies. And to establish the taxonomic position. One taxon distributed in north Korea was included in the description of species by observation of herbarium specimen of the University of Tokyo in Japan. The two sections were successfully distinguished by internal structure of ovary, morphology of nectary, number of corolla lobe and calyx lobe, and species were also distinguished by morphology of cauline leaf, and color and spot of corolla, respectively. The variation type of Ophelia wilfordi was not distinguished with other species except for absent or present of purple spot in corolla lobe. The results of the discriminal functional analysis indicated that characters of corolla were the most important qualitative characters to distinguish the Ophelia taxa, and morphology of seed and seed coat was useful characters to distinguish taxa higher than species. Therefore the difficult problems of identification of species were successfully solved, and the taxonomic position in intrageneric level was clarified on Korean Ophelia.

• Journal of the Korean Association of Geographic Information Studies
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• v.11 no.3
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• pp.13-22
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• 2008

The objective of this study is to evaluate the applicability of extracted PRMS input parameters by KGIS-Hydrology over Yongdam-Dam watershed. KGIS-Hydrology is a system for automatic extraction and analysis of watershed characteristic data. Input parameters of PRMS were generated from GIS data (DEM, soil, forest type, etc.) using KGIS-Hydrology. Multi-temporal meteorological data from Jangsu station of KMA (Korea Meteorological Administration) were used for all simulation periods. Input parameters of PRMS were optimized using observed runoff data of Yongdam-Dam station (1966-2001) and validated using observed runoff data of Yongdam-Dam station (2002-2006, Yongdam-Dam watershed). The results showed that the simulated flows were much closed to the observed flows of Yongdam-Dam (2002-2006) and Donghyang (2001-2004) station by 0.49~0.83 and 0.57~0.75 model efficiencies, respectively.

• Journal of Life Science
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• v.8 no.5
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• pp.532-536
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• 1998

This study was designed to observe the effects of the feeding Gentiana scabra Bunge var.buergeri Max. extract on the improvement of the blood glucose, lipids in the serum of dietary hyperlipidemic rats (S.D. strain, ♂) fed the experimental diets for 4 weeks. Concentration of blood glucose was significantly higher in the cholesterol administration groups (group 2(cholesterol+water), 3(cholesterol+Gentiana scabra Bunge extract) than those in the control group(group 1 (water)). Blood glucose concentration was rather lower in the group 3(cholesterol+Gentiana scabra Bunge extract) than in the group 2(cholesterol+water). There was almost little significance among the groups. Concentration of total cholesterol in serum was significantly lower in the group 3 than those in the group 2. Concentration of LDL-cholesterol in serum was significantly lower in the group 3 than that in the group 2. In the ratio of HDL-cholesterol concentration to total cholesterol concentration, Gentiana scabra Bunge extract administration group was higher percentage than in the group 2. Concentration of free cholesterol and cholesteryl ester in serum was significantly lower in the group 3 than in the group 2. Concentrations of triglyceride and phospholipid in serum were decreased in the group 3 than in the high fat diet group. The activities of aspartate aminotransferase and alanine aminotransferase in serum were increased in the all experimental groups than in the control group. From the above research, the Gentiana scabra Bunge var.buergeri Max. exacts were effective on the improvement of the lipid composition in serum of dietary hyperlipidemic rats.

• Journal of Wetlands Research
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• v.14 no.1
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• pp.147-158
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• 2012

Recently, there have been a lot of studies for the value for wetlands with increased interest about wetlands. However, the value assessment for wetlands was usually conducted for natural wetlands only, without consideration for Dam-wetlands. In this study, we assumed that a dam carried out a function of wetlands and defined such dams as Dam-wetlands. Contingent Valuation Method(CVM) was used in value assessment method. Study area of this study is Yongdam-dam. We performed questionnaire survey in six metropolitan cities for the value assessment of Dam-wetland. As a result, the total values of a Yongdam-dam is estimated as 4.2 billion-won for construction scenario of wetland ecological park.

• The Journal of Korean Medicine
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• v.22 no.2
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• pp.102-108
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• 2001

목적 : 단순포진바이러스로 유발한 베체트병 마우스 모델에서 가미청혈보혈탕과 가미 용담사간탕을 colchicine과 함께 투여할 경우, 한방 혹은 양방 단독 투여의 경우와 비교하여 베체트병 증상의 호전에 어떠한 영향을 주는지 알아보고자 하였다. 방법 : colchicines, 가미 청혈보혈탕, 가미용담사간탕을 각각 또는 colchicines+가미 청혈보혈탕, colchicines+가미용담 사간탕을 20일간 복합 투여하여 베체트 증상이 호전되는 정도를 살펴보고, 호전 되는 증상의 종류를 파악하고, 이때 동반되는 싸이토카인을 RT-PCR, FACS등으로 확인하고자 하였다. 결과 : 단독투여군보다 복합투여군에서 증상이 호전되는 율이 높았으며, 호전 시기를 앞당겼고, 이때 싸이토카인 interteukin-4의 발현이 증가하였다. 결론 ; 베체트병 마우스 모델에서, 양방과 한방의 복합투여가 단독투여보다 증상의 호전에 보다 더 효과적이었다.