• 제목/요약/키워드: 온열생리 반응

검색결과 38건 처리시간 0.021초

극초단파를 이용한 국소온열 치료 효과 -표재성 종양 42예의 분석- (Effect of Microwave Hyperthermia on Radiotherapy of Human Malignant Tumors -An Analysis of Clinical Response of 42 Patients-)

  • 윤세철;오윤경;길학준;정수미;신경섭;박용휘
    • Radiation Oncology Journal
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    • 제5권1호
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    • pp.31-36
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    • 1987
  • 인간이 각종 질병치료에 있어 열(온열)을 이용한 것은 고대의학의 시작과 그 역사가 함께 비롯된다. 이러한 온열요법은 방사선치료나 일부 항암약제와 병행할 때 그 효과가 상승되며 그 단독 사용만으로도 암세포를 죽일 수 있음이 최근에 와서 밝혀지고 있고 또한 병태생리학적 기전이 규명되고 있다. 한편, 온열치료기계 및 온도측정장치의 개발로 말미암아 암환자 치료에 온열치료의 임상적 응용이 각광을 받고 있다. 가톨릭의대 강남성모병원 방사선치료실에서는 1985년 3월 이후 1년 9개월 동안에 표재성의 전이 또는 원발암환자 42예(남 23예, 여 19예 ; 평균연령 56세)에서 외부방사선치료 또는 항암약물치료와 병행하여 가정용 전자레인지를 개조하여 만든 2,450MHz 극초단파를 이용한 온열치료를 실시하였다. 이 중 6예에서는 방사선치료 종료 후 재발되었기에 온열치료 단독으로 실시하였다. 온열치료 후 임상적 반응은 총 42예 중 종괴의 완전관해 부분관해 소관해 및 무관해율이 각각 11예$(20\%),\;15예(36\%),\;11예(26\%)\;및\;5예(12\%)$였다. 조직학적 진단은 편평상피암 $17예(40.5\%)$, 선세포암 12예$(28.0\%)$ 및 기타암종이 6예$(14.5\%)$였다. 완전관해를 보인 11예의 조직학적 진단은 편평상피암 5예, 선세포암 5예, 녹색종이 1예 였으며, 부분관해를 보인 15예는 편평상피암 5예, 선세포암 5예, 불명암 3예 및 미분화세포암과 기타암종이 각각 1예씩이었다. 방사선치료선량과 온열치료 횟수와의 관계는 $40\~50Gy/5\~7$주의 방사선치료와 1회 30분씩 주 2회, 총 $5\~9$회의 온열치료를 실시하였던 군에서 가장 온열치료효과가 좋았던 것으로 분석되었다. 한편 온열치료의 부작용으로는 일시적 치료부위 발적이 모든 환자에서 관찰되었으며 수술 후 켈로이드에 재발되었던 유방암환자 1예에서 자연치유되는 2도 화상을 경험하였다.

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흡열제가 첨가된 일회용 기저귀의 착용이 유아의 온열생리적 반응에 미치는 영향 (Effects of wearing disposable diaper with the endothermic agent on thermal responses of infant)

  • 성유진;이수원
    • 한국의류학회지
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    • 제23권4호
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    • pp.499-509
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    • 1999
  • This study was carried out to investigate the effects of wearing disposable diaper with the endothermic agent on thermoregulatory response of infant. Five healthy female infants aged about 5 months were taken as a subject of this experiment. Experimental diapers were six kinds of disposable diaper constructed of nonwoven tissue, fluff pulp, super absorbent polymer, back sheet film, leg elastic, and 0g urea(A) 1g urea(B) , 2g urea(C), 3g urea (D), 4g urea(E) 5g, urea(F) respectively. Urea(98% or over purity) was used as an endothermic agent. Experiment was proceeded while infants were sleeping at 27.5$\pm$0.5$^{\circ}C$, 50$\pm$5% R.H, 0.04m/sec. Each disposable diaper's properties was tested. During the experiment rectal temperature skin temperature of 9 areas temperature inside the disposable diapers were measured, the results were as follows : 1) There was not significant difference among the diapers in absorption capacity retention capacity and rewet(p=0.05). The absorption under load was showed to A, B,

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옥외에서 원적외선 방사직물 착용시 온열생리반응 (Thermo Physiological responses of Far Infrared Ray Radiation Fabrics at outdoor in summer)

  • 송명견;안필자;최정화
    • 한국농촌생활과학회지
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    • 제7권2호
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    • pp.121-128
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    • 1996
  • This study was performed to define the effects of Far Infrared Ray Radiation Fabrics as summer garments during outdoor work by human trial. One healthy male subject was volunteered for this study. Experimental garments consisted of three kinds of trousers (Cotton, Cotton/linen blended, Far Infrared Ray Radiation Fabric/wool blended) and basic garments (panty, socks, shirts, and dress shirts). The measurements were rectal temp., skin temp., microclimate inside clothing, heart rate, subjective sensation etc. The results were as follows : 1. Rectal temperature showed the lowest in Far Infrared Ray Radiation Fabrics among 3 garments. 2. Skin temperature (forehead, chest abdomen temp.) and mean skin temperature were lower in Far Infrared Ray Radiation Fabrics than in others, especially during early stage of work. 3. Heart rate showed lower value in Far Infrared Ray Radiation Fabrics than in others but there was no significance among the garments. 4. Humidity inside clothing and total weight loss showed the highest value in Far Infrared Ray Radiation Fabrics.

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상반신의 부분별 발한량, 피부온과 주관적 감각 고찰 (The Analysis of the Sweating Rate, Skin Temperature on the Upper Body and Subjective Sensations)

  • 김성숙;김희은
    • 한국의류산업학회지
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    • 제15권6호
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    • pp.993-999
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    • 2013
  • This study aimed to measure the amount of sweating on 12 parts of the upper body using absorption fabric and analyze subjective sensations. The study was conducted with 9 male subjects in climate chamber controled at $30{\pm}0.5^{\circ}C$, and $55{\pm}5%$ RH. The result was that sweating amount of the upper back part was significantly more than upper front part. We assumed that forced convection flow cased by exercise decreased the sweating rate in the front. The skin temperature of upper front body rapidly decreased as soon as exercise starts and gradually increased with cessation of exercise. On the other hand, the skin temperature of palm increased with exercise and showed continuous increasing even exercise stopping all the experimental period. This is caused by thermoregulatory responses through vasodilatation on the peripheral area. Subjective sensations, such as thermal sensation, wet sensation, and thermal comfort showed the highest score at the time of exercise stop. This means the subjects felt more hot, wet, and uncomfortable after exercise stopped. Bur after wiping of sweat, subjective sensation scores were recovered rapidly. The present study has provided more detailed information on the upper body sweat distribution than previously available, which can be used in clothing design, thermo-physiological modeling, and thermal manikin design. We also think that results of the present study will play an important role in making the sweat distribution map.

온돌난방에서의 자세에 따른 온열생리적 반응의 성차 (Effectsd of posture on physiological thermal responses with Ondol heating system)

  • 신정화;최정화
    • 한국의류학회지
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    • 제22권8호
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    • pp.1020-1031
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    • 1998
  • This study was done to investigate thermal reponses and to obtain the basic information of thermal comfort by sex and posture under the Ondol heating system. Six healthy males and females were exposed to Ondol(Room Temp.: 25$\pm$1$^{\circ}C$, 50$\pm$10%R.H, Floor Temp.:30$\pm$1$^{\circ}C$) on the of posture such as sitting, lying aside and supine on the floor for 30 minutes after 30 minutes' control phase. During the experiment, rectal temperature, skin temperature of 10 areas, local sweating rate, clothing microclimate, subjective sensation were measured. Rectal temperature gradually decreased and mean skin temperature grad-ually increased both male and female in any posture. There was not significant difference between male and female in rectal temperature and mean skin temperature. There were significant difference among the postures in rectal temperature(p<0.001) and mean skin temperature(p<0.001). In lying aside and supine on the floor, appearances of change and changes in rectal temperature and mean skin temperature were large, changes of weight were small. In sitting on the floor, appearances of change and changes in rectal temperature and mean skin temperature were small, changes of weight were large. The trunk skin tem-perature was higher in female than in male, but the extremity skin temperature was higher in male than in female. In sitting on the floor, foot skin temperature(p<0.001) was higher than any other local skin temperature. In supine on the floor, back skin temperature(p<0.001) was higher than any other local skin temperature.

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운동에 의한 열 스트레스하에서 흡한속건성 소재 운동복 착용시의 온열생리적 반응 및 주관적 감각 (Thermophysiological Responses and Subjective Sensations when Wearing Clothing with Quickly Water-Absorbent and Dry Properties Under Exercise-Induced Heat Strain)

  • 이소진;박신정
    • 한국의류산업학회지
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    • 제8권3호
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    • pp.349-356
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    • 2006
  • The purpose of this study was to compare the thermophysiological responses and subjective sensations of clothing materials with different water transfer property investigated in exercising and resting subjects at an ambient temperature of $20^{\circ}C$ and a relative humidity of 40%. Two kinds of clothing ensemble were tested: 100% cotton with highly water-absorbent but slowly dry properties(C) and 100% polyester with quickly water-absorbent and dry properties by four capillary channels(QADP). Seven apparently healthy male participants each undertook two series of experiments comprised 10-min of rest, 20-min of exercise with 70% of $VO_{2max}$ on a treadmill and 20-min of recovery. Mean skin temperature was significantly lower in QADP than in C during exercise and recovery. Clothing microclimate temperature was significantly lower in QADP during exercise and clothing surface temperature was also lower in QADP especially during recovery. Also, clothing surface humidity was significantly higher in QADP after the later half of exercise. The concentration of blood lactic acid tended to decrease to a lower level at recovery 3 minutes when wearing QADP rather than C clothing ensemble. Metabolic energy was marginally significantly less during the second half of exercise in QADP. Body mass loss tended to be greater in C than in QADP. The participants had better scores in thermal sensation, comfortable sensation and wetness in QADP during exercise and recovery. These results show that functional materials with quickly water-absorbent and dry properties can alleviate heat strain and induce more comfortable clothing microclimates and subjective sensations in the exercise-induced hyperthermia.

온돌환경이 수면시의 생리반응엔 미치는 영향 -봄철 수면시 침실내 온열환경과 침상기후- (Effect of Ondol Environment on Physiological Regponseg during Sleeping (II) The Actual Conditions of Bedclimate in Spring -)

  • 이순원;권수애
    • 한국의류학회지
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    • 제21권3호
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    • pp.516-523
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    • 1997
  • The actual conditions of bedclimate are investigated depending on the regions and housing styles used on ondol in spring. Sixty healthy men and women (30 of them live in apartment and 30 of them live in detached house, 20 of them live in Wonju, 20 of them live in Cheongiu and 20 of them live in Pusan). The results are as follows: 1) The differences of bedclothes thickness between spring and autumn were not significant. weight of sleep-wear in spring was less than those in the autumn. 2) In the spring, the temperature and humidity of bedroom, floor, on/under the mattress, were lower and the temperature inside the sleep-wear was higher than those in the autumn. 3) The differences of the temperature and humidity of bedroom, the bed climate, and the clothing microclimate were significant by the regions and housing styles in spring. The temperature of bedroom and inside sleep-wear, the humidity of bedroom and inside sleep- wear in the apartment were higher than those in the detached house. 4) The differences of comfort sensation on the bedroom conditions was significant by the regions, and the differences of thermal sensation was significant by the housing styles. Most subjects perceived warm and dry but comfortable.

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자동차 에어컨 쾌적제어 알고리즘 개발을 위한 운전자 온열감성 평가 : 제 2보-운전자의 생리반응 (Comfort Control Algorithm Development of Car Air Conditioner using Thermal Comfort Evaluation of The Driver : Part II-Physiological Response of Driver)

  • 김민수;김동규;박종일;금종수
    • 설비공학논문집
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    • 제28권6호
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    • pp.217-223
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    • 2016
  • In this study, we investigated the operating method of a driver for an air conditioning system according to the temperature difference between the indoor and outdoor environments of a car parked outside during the summer. Researchers of this study suggest the comfort mode of a car air conditioner to improve the thermal comfort of the driver, thereby maintaining longer comfort. This study separately, analyzed temperatures on a cloudy day and sunny day. The results showed the car indoor heat environment and physiological results (EEG, ECG) of the subject. It showed a difference of the car indoor heat environment by weather with the difference also appearing in the physiological response of the subject. In conclusion, in this paper, on the basis of the physiological response of a subject, a comfortable algorithm of automobile air conditioner is being suggested.

운전자의 심리·생리 반응을 고려한 승용차 쾌적 난방 모드에 관한 연구 (Research on the Thermal Comfort Heating Mode Considering Psychological and Physiological Response of Automobile Drivers)

  • 김민수;금종수;박종일;김동규
    • 설비공학논문집
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    • 제30권3호
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    • pp.149-157
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    • 2018
  • In this research, the psychological and physiological reactions of the driver were measured during winter to evaluate thermal comfort. The experiment was conducted using 3 different cases which are hot air heating, warm-wire seat heating and hot air & warm-wire seat heater operating simultaneously. With regard to psychological reaction, the warm-wire heating mode was the most preferred. The reason is that it is dry in other cases. With regard to EEG response, thermal comfort increased by 37% in warm air mode heating. In addition, when the warm-wire heating mode and the hot air & warm-wire heating mode were simultaneously operated, the thermal comfort continuously increased by between 17% and 20% for 20 minutes after boarding. Under the change of the autonomic nervous system, the thermal stress level increased by 23% after 15 minutes on board in the hot air heating mode and decreased continuously by 13% during the warm-wire seat heating mode. We recommended the hot air heating mode is only used for a short time to raise the inside temperature during the early boarding period and that warm-wire seat heating mode be actively utilized.

멀티모달 실감 경험 I/O 인터랙션 시스템 개발 (Development for Multi-modal Realistic Experience I/O Interaction System)

  • 박재언;황민철;이정년;허환;정용무
    • 감성과학
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    • 제14권4호
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    • pp.627-636
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    • 2011
  • 본 연구는 단순 입력 기반 유니모달 인터랙션의 한계를 극복하고 단순 입력 방식이 아닌 멀티모달 기반 사용자의 행위, 의도, 및 집중도를 활용하여 실감적이고 몰입도를 향상시키는 인터랙션 시스템을 제안하는데 그 목적이 있다. 본 연구의 선행연구에서 기존 문헌연구를 토대로 메타분석방법을 활용하여 인터랙션을 위한 3차원 동작 인식 기술의 정확도를 분석하여 최종적인 센서 기반 인터랙션 방법이 선정되었고, 직관적 제스쳐 인터랙션 요소를 추출하여 본 시스템에 반영하였다. 또한 생리반응을 이용한 집중력 판단 기술을 개발하여 사용자 의도를 판단하는 연구를 진행하였다. 본 연구에서 제안하는 시스템은 3부분으로 나눌 수 있다. 선행연구에서 선정된 인터랙션 요소들을 적용하여 가속도(Accelator) 센서와 연성(Flexible) 센서를 활용하여 손 동작을 인식하는 시스템을 구현하였고, 동공 인터랙션을 통한 안경형 시선 추적기를 구현하여 인터랙션이 가능하게 하였으며, 심혈관 반응과 피부 온열 반응을 측정하여 사용자의 의도를 반영한 시스템을 최종 구현하였다. 실감형 디지털 엔터테인먼트 플랫폼 기술 개발을 위한 기초 연구로서 활용이 가능할 것으로 판단된다.

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