• Journal of the Korean Applied Science and Technology
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• v.30 no.2
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• pp.339-347
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• 2013

Nano-emulsions are submicron sized emulsions that are under extensive investigation as drug carriers for improving the delivery of therapeutic agents. The aim of this research is to investigate the stability of nano-emulsions containing polymers. Nano-emulsions containing high concentrations of Carbopol 941, Aristoflex AVC, Aronbis M, Permulen TR 2 and Aculyn 44 were unstable compared with macroemulsions with polymers. The size of emulsion droplet manufactured by adding polymer before emulsification were larger than that of emulsion manufactured by adding polymer after the emulsification. The stability of nano-emulsion containing a low concentration of polymer was also decreased, however the effect was lower than that in the high concentration of polymer. Under similar viscosity of polymer, the sequence of unstability was Aristoflex AVC < Carbopol 941 < Permulen TR2 < Carbopol 941 + Aculyn 44 < Aronbis M.