• Journal of agricultural medicine and community health
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• v.31 no.3
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• pp.219-236
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• 2006

Objectives: To develop a model of a official management system for agricultural disease, injury and accidents, We analyzed current Korean status and management system about occupational injury and accident of farmers. Methods: For national management systems of industry safety and health and current status of occupational injuries and accidents of farmers, related literature such as books, theses, articles, and web documents were collected and analyzed. Results and Conclusion: The regulations of protecting occupational injury and accidents of farmers are suggested as follows: (1)insurance and compensation act for occupational injury and accident of farmers, (2)setting standards of occupational injuries and accidents of farmers, (3)mandating the usage of safety devices for agricultural vehicles and equipments, (4)reporting occupational injuries and accidents that occur among farmers, (5)registering pesticides and assessing safety usage, (6)implementing safety training, (7)supporting personal protective equipments and agricultural safe facilities etc.

• Journal of Korea Port Economic Association
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• v.30 no.4
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• pp.47-67
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• 2014

This study examined elements which could evaluate a container terminal logistics system from the viewpoint of supply chain management. This study derived the elements of a container terminal logistics system such as flexibility, reliability, responsiveness, and information sharing and 16 evaluation sub-items in the aspect of a supply chain. In the result of analysis, the weight between SCM elements of a container terminal logistics system was the highest in reliability(0.282), followed by flexibility(0.273), responsiveness(0.224), and information sharing(0.221). The conversion weight was calculated by combining the weight of elements of a container terminal logistics system and the weight of evaluation sub-items. The highest weight which was considered as the most important factor to evaluate a container terminal logistics system was work planning(berth, yard) of flexibility(0.081), followed by accurate fulfillment of container work schedule(ship, yard) and the optimum distribution and arrangement of equipment(QC, TC, YT)(0.079), stable works without damage of containers and ships(0.071), and preventive maintenance of equipment and operators' skill(0.070).

• Journal of Life Science
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• v.26 no.8
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• pp.983-989
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• 2016

All cells composing of our body undergo their destiny such as proliferation, differentiation, necrosis, apoptosis and senescence depending on their circumstance with time. The errors occurring in these processes develop several aberrations in phenotypes including cancer, inflammation, aging and diseases. New strategy and approach are required to screen anti-aging compounds derived from natural products. Therefore, here we explain the target proteins to play a key role in aging mechanism. In the first place, matrix metalloproteinases (MMPs) are involved in metastasis, chronic inflammation and skin aging as an aging marker. In particular, histone deacetylases (HDACs) give a great attention to aging researchers who try to extend the life span of animal model. In addition, we describe the signaling pathway related to senescence which p53, IGF-1 and SIRT1 play an important role in. Furthermore, autophagy is involved in the signaling pathway associated with aging. Several new compounds modulating the signaling pathway of senescence are introduced in this review. Here, we try to provide a new insight in the molecular basis for the aging mechanism and development of aging marker. In addition, the compounds introduced here could be available for pharmaceutical applications for the prevention and the treatment of diseases related to aging.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1283-1293
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• 2013

The purpose of this study was to compare the health behaviors, mental health and internet addiction by gender differences among Korean adolescents and to examine relevances between health behaviors, mental health and internet addiction. The subjects were 73,238 Korean adolescents(male: 38,391, female: 34,847) who were recruited through national web-based survey. The data were derived from the Sixth Korea Youth Risk Behavior Web-based Survey 2010 in South Korea. There were significant differences in health behaviors, mental health and internet addiction. by gender differences. Prevalence of internet addiction was male: 3.9%, female: 1.9% in this study. As the result of multiple logistic regression, the risk of internet addiction was increased in the case of smoking experience, substance experience, subjective health status, feeling of stress, depression experience, suicidal ideation, feeling of happiness, and sufficiency of sleeps in both male and female. Therefore, to decrease internet addiction prevalence, it is necessary to detect and manage the influencing risk factors of internet addiction such as health behaviors and mental health. And the health-promotion intervention to improve the internet addiction of adolescents should be planed and provided considering such differences by gender differences.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.6
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• pp.1-14
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• 2012

Traffic management centers (TMC) collect real-time traffic data from the field and have powerful databases for analysing, recording, and archiving the data. Recent advanced sensor and communication technologies have been widely applied to intelligent transportation systems (ITS). Regarding sensors, various in-vehicle sensors, in addition to global positioning system (GPS) receiver, are capable of providing high resolution data representing vehicle maneuverings. Regarding communication technologies, advanced wireless communication technologies including vehicle-to-vehicle (V2V) and vehicle-to-vehicle infrastructure (V2I), which are generally referred to as V2X, have been widely used for traffic information and operations (references). The V2X environment considers the transportation system as a network in which each element, such as the vehicles, infrastructure, and drivers, communicates and reacts systematically to acquire information without any time and/or place restrictions. This study is motivated by needs of exploiting aforementioned cutting-edge technologies for developing smarter transportation services. The proposed system has been implemented in the field and discussed in this study. The proposed system is expected to be used effectively to support the development of various traffic information control strategies for the purpose of enhancing traffic safety on highways.

• Food Science and Industry
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• v.40 no.2
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• pp.46-58
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• 2007

제2형 당뇨병은 대사성 질환으로 간, 근육 그리고 지방 조직 세포에서 인슐린 작용의 장애로 나타나는 인슐린 저항성으로 혈당의 이용이 감소하여 혈당이 높아짐에도 불구하고 췌장의 베타세포에서 인슐린 분비가 충분하지 못할 때 유발된다. 서구에서는 비만 등으로 인해 인슐린 저항성이 증가하면 인슐린 분비가 높은 고인슐린혈증을 나타내어 당뇨병으로의 진전은 늦다. 하지만 우리나라를 비롯한 아시아의 사람들은 인슐린 저항성이 증가할 때 인슐린 분비가 충분치 못해 혈청 인슐린 농도가 정상인과 비슷하거나 더 낮은 상태에서 당뇨병으로 진전된다. 이러한 차이는 우리나라를 비롯한 아시아 사람들에게서 제2형 당뇨병의 발생이 급격하게 증가할 것이라는 보고되었다. 결국 당뇨병은 간, 근육 및 지방조직에서의 인슐린 작용의 장애와 췌장의 베타세포에서 인슐린 분비의 부족의 복합적인 장애에 의해서 나타나고 이것은 공통적으로 각 조직에서의 인슐린/insulin growth factor (IGF)-1 신호전달의 장애와 관련이 있다. 베타세포에서의 인슐린분비 자체는 인슐린/IGF-1 신호전달과 관계가 없지만 간접적으로 관련이 있다. 인슐린 분비능은 베타세포의 증식과 생존에 의한 베타세포의 양과 밀접한 관련이 있는데 인슐린/IGF-1 신호전달은 베타세포의 증식과 생존을 조절한다. 그러므로 혈당 조절에 관여하는 기능성 식품은 인슐린 작용을 향상시키는 인슐린 민감성 특성을 가지거나, 혈당이 높아질 때 인슐린 분비를 촉진시키는 insulinotropic 작용을 하는 성질을 가지고 있어야 하겠다. 전자의 대표적인 약은 1999년에 미국 FDA에서 승인 받은 peroxisome proliferator-activated receptor $(PPAR)-{\gamma}$ agonist 인 thiazolidinedione 계통의 약물인 troglitazone, pioglitazone, rosiglitazone 등이 있고, 후자는 2007년에 승인 받은 Exenatide는 glucagon like peptide (GLP)-1 agonist이다. 이 두 가지 약은 모두 자연계에 존재하는 동식물에서 유래된 것으로 식품에도 많이 다양한 종류의 인슐린 민감성 물질이나 insulinotropic 작용을 하는 물질이 함유되어 있을 것이다. 이러한 기능 이외에 혈당조절 약이나 식품으로 사용되는 것은 탄수화물의 소화를 방해하는 것으로 탄수화물 소화효소인 a-amylase 또는 maltase의 활성을 억제하여 식후 혈당의 급격한 상승을 방지하는 것이 있다. 우리나라 사람들은 탄수화물의 섭취가 너무 많아서 실제로 이러한 식품이나 약의 효능이 높지 않을 것이다. 혈당을 조절하는 기능성 식품은 이 세 가지 효능 중 일부를 가지고 있는 것이 될 수 있다. 이러한 기능을 스크리닝하기 위해서 3가지 단계를 거쳐야 한다. 먼저 시험관에서 또는 세포 실험을 통해서 앞서 언급한 3가지 기능을 가지고 있는 지 여부를 각각 조사한다. 이중에서 효과가 있는 것은 당뇨 동물 모델을 사용하여 in vivo에서 혈당 강하기능과 혈당 강하기전을 조사하는 실험을 한다. 효과가 있는 식품이 우리가 전통적으로 식품으로 섭취해 왔다면 독성 검사를 거쳐야 할 필요가 없지만 한약재이거나 특수 식품의 경우에는 in vivo 실험 전에 GLP 기관에서 반드시 독성 실험을 거쳐 독성 유무를 확인할 필요가 있다. 동물 실험에서 효과적인 것은 인체 실험을 거쳐 혈당 조절 기능성 식품으로 식약청에서 허가를 받을 수 있겠다. 결론적으로 식품에는 항당뇨 특성을 가진 물질들이 함유되어 있는 것들이 상당히 많다. 혈당 조절기능이 있는 기능성 식품으로 개발할 때 고려해야 할 것은 1) 그 양이 혈당 강하 기능성 식품으로 지정받을 수 있을 정도로 충분히 함유되어 있느냐, 2) 혈당을 강하시키는 기전이 단순히 당의 배설을 촉진시켜서 혈당을 저하시키는 것이 아니라, 인슐린 작용을 촉진시키거나, 포도당 자극에 의한 인슐린 분비를 촉진시키거나 탄수화물의 소화 흡수를 억제시킴으로 혈당을 강하시키는 지 등을 파악하는 것이다. 이러한 조건을 만족시키는 식품은 지속적으로 섭취할 때 당뇨병을 예방하거나 진전을 지연시킬 수 있는 혈당조절기능이 있는 기능성 식품으로 개발 가능성이 있겠다.

• 한국노년학
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• v.28 no.4
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• pp.969-989
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• 2008

This study attempts to explain how depression among community elderly relate to suicidal ideation and whether or not the psycho-social characteristics of elderly persons moderate the relationship between these two variables. This study was conducted in Seoul, Busan, and Daegu and included 273 persons 65 years and above who were using senior welfare centers in the communities. For the questionnaire and analysis, this research uses the Health Care, Life Event, Self-esteem, Family Assessment scales. This research utilizes a wide range of statistical analyses, such as descriptive analysis, Pearson's correlation, reliability analysis, multiple regression, and general linear modeling. The calculations employed the use of SPSS/PC+ 12.0. This research indicates, among other things, that elderly persons with a high level of depression and psycho-social characteristics show a tendency toward higher suicidal ideation and that the level of self-esteem, life event, and family communication plays a moderating role in the relationship between depression and suicidal ideation among community elderly. In conclusion, elderly persons who experienced with a high level of psycho-social characteristics shows a relatively greater tendency toward suicidal ideation when compared to elderly persons having a low level of psycho-social characteristics. The intervention's effectiveness in reducing suicidal ideation can reinforce self-esteem, and cope with stressful life events and family discord as prevention strategy to reduce risk factors for suicide in late life.

• Journal of the Korean Society of Child Welfare
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• no.53
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• pp.1-23
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• 2016

With using a subsample of 1,373 poor single mothers and their children from the Fragile Families and Child Wellbeing study, the present study examined the associations among mothers' economic hardship, depressive symptoms, and parenting stress, child abuse and neglect, and their children's behavior problems, delinquency, and social skill. These families were tracked through follow-up interviews at the time of birth, and when the children were three, five, and nine years old. The results indicated that mothers' economic hardship, depressive symptoms, and parenting stress were significant predictors to determine their children's abuse and neglect. Findings also suggest that higher levels of child abuse and neglect are positively associated with more behavior problems and delinquency, and negatively associated with social skills. Further discussions include policy and services to prevent child abuse and neglect and to alleviate mothers' financial difficulties, depression, and parenting stress.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.467-477
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• 2021

Purposes of this study were to identify the relationship among involvement in COVID-19 (IiC), attitude toward advertisement (AtA), and behavioral Intention to social distancing (BItSD), and to investigate the mediating effect of AtA in a loss versus gain advertising context. The participants were 379 adults who have been consecutively living in Korea since January 2020. The participants were randomly assigned to one of two advertisements using an online survey system. We found that IiC affects BItSD since Korean adults recognize the risks and seriousness of COVID-19 infection or transmission through IiC. Induced positive attitudes or emotions through involvement in the COVID-19 preventive behaviors including social distancing and vaccination are helpful to increase the BItSD. Thus, health care and information providers should give an accurate message, which induces a positive attitude, to recognize that our world is a risk of the COVID-19.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.1
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• pp.86-92
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• 2019

Di-ethylhexyl phthalate (DEHP) is an environmental contaminant that is used as a plasticizer. Endometriosis is a complex disease with an unknown etiology that is believed to be associated with exposure to DEHP. The present study examined the potential toxicity of DEHP by exposing endometrial adenocarcinoma cells (Ishikawa cells) to DEHP. In the experiments, the cells were treated with stepwise DEHP concentrations (0, 0.01, 0.1, 1, and $5{\mu}M$) for different exposure times (24, 48, and 72 h). When the relationship between the resulting survival rate of the cells and initial inflammation was examined, the cell viability, expression of $TNF-{\alpha}$, an inflammatory mediator, and the expression of MMP-9, an ECM degradation protein, were increased remarkably when the cells were exposed to $5{\mu}M$ DEHP for 48 and 72 hours. These results suggest that the exposure of Ishikawa cells to certain concentrations of DEHP, estrogen mimics, may cause time-dependent toxicity that affects the cell viability and inflammation, implying a potential role in the etiology of endometriosis. Further research on the effects of endocrine disruptors on the pathogenesis of endometriosis may reveal strategies to prevent this disease.