• 제목/요약/키워드: 엽 투과도

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Pharmacological activity of extracts Artermisia iwayomogi : liver regeneration and chronic hepatotoxicity

  • Lee, Soon-Bok;Cheol Jeong;Jeong, Seong-Hak;Lee, Sun-Mee;Cho, Tai-Soon
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.200-200
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    • 1996
  • 간재생 및 만성 간질환모델에 대한 인진호 추출분획의 간장 약효검색 방법 1. 간세포 재생능력에 대한 효과 : SD계 수컷 흰쥐(체중 300-350g)를 마취하에서 복부정중선을 따라 개복후 간의 중앙엽 및 좌측엽을 절제하여 봉합하고 수술조작을 끝낸 추 4시간, 익일부터 7일간 오후 5시에 약물을 경구투여하고 마지막투여 후 20시간 절식, 부검하여 간재생률 및 BSP 정체율을 측정하였다. 2. $CCl_4$ 만성간장해 모델에 대한 효자 SD계 수컷 흰쥐(체중 200-250g)에 $CCl_4$ : olive oil 40%용액을 0.5 $m\ell$/kg b.wt. 용량으로 6일간 결구투여 한 후 7일째부터 매일 시험약물을 $CCl_4$ 혼합액 투여 4시간전 및 4시간후에 2회 경구투여하였으며 이 조작을 8일간 하고 마지막 투여 24시간 후에 부검하여 혈액내 ALT 및 AST치, 간조직내 total protein, triglyceride 및 hydroxyproline 양을 측정하였으며, 간중량도 측정하였다. 3. 약물투여 음성대조 : 1% CMC-Na 용액(10$m\ell$/kg b.wt.) 양성대조 : silymarin(25mg/kg), DDB(37.5mg/kg) 인진호추출분획 : KP(180mg/kg), PS-1(300mg/kg), PS-2(300mg/kg), EE (500mg/kg ), HH(640mg/kg), BE(1500mg/kg)

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Analysis of dosimetric leaf gap variation on dose rate variation for dynamic IMRT (동적 세기조절방사선 치료 시 선량률 변화에 따른 선량학적엽간격 변화 분석)

  • Yang, Myung Sic;Park, Ju Kyeong;Lee, Seung Hun;Kim, Yang Su;Lee, Sun Young;Cha, Seok Yong
    • The Journal of Korean Society for Radiation Therapy
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    • v.28 no.1
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    • pp.47-55
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    • 2016
  • To evaluate the position accuracy of the MLC. This study analyzed the variations of the dosimetric leaf gap(DLG) and MLC transmission factor to reflect the location of the MLC leaves according to the dose rate variation for dynamic IMRT. We used the 6 MV and 10 MV X-ray beams from linear accelerator with a Millennium 120 MLC system. We measured the variation of DLG and MLC transmission factor at depth of 10 cm for the water phantom by varying the dose rate to 200, 300, 400, 500 and 600 MU/min using the CC13 and FC-65G chambers. For 6 MV X-ray beam, a result of measuring based on a dose rate 400 MU/min by varying the dose rate to 200, 300, 400, 500 and 600 MU/min of the difference rate was respectively -2.59, -1.89, 0.00, -0.58, -2.89%. For 10 MV X-ray beam, the difference rate was respectively ?2.52, -1.69, 0.00, +1.28, -1.98%. The difference rate of MLC transmission factor was in the range of about ${\pm}1%$ of the measured values at the two types of energy and all of the dose rates. This study evaluated the variation of DLG and MLC transmission factor for the dose rate variation for dynamic IMRT. The difference of the MLC transmission factor according to the dose rate variation is negligible, but, the difference of the DLG was found to be large. Therefore, when randomly changing the dose rate dynamic IMRT, it may significantly affect the dose delivered to the tumor. Unless you change the dose rate during dynamic IMRT, it is thought that is to be the more accurate radiation therapy.

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Evaluation of Dosimetric Characteristics of a Double-focused Dynamic Micro-Multileaf Collimator (DMLC) (이중으로 집중된 동적 미세 다엽콜리메이터의 선량학적 특성 평가)

  • Kim, Ae Ran;Seo, Jae-Hyuk;Shin, Hun-Joo;Park, Hyeong Wook;Lee, Ki Woong;Lee, Jae Choon;Kim, Shin-Wook;Kim, Ji Na;Park, Hyeli;Lee, Heui-Kwan;Kang, Young-Nam
    • Progress in Medical Physics
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    • v.26 no.4
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    • pp.223-228
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    • 2015
  • Double-focused micro-Multileaf Collimator (${\mu}MLC$) is able to create radiation fields having sharper dose gradients at the field edges than common MLC. Therefore, ${\mu}MLC$ has been used for the stereotactic radiosurgery (SRS) and Stereotactic Radiotherapy (SRT). We evaluated the dosimetric characteristics of a doublefocused Dynamic-${\mu}MLC$ (DMLC) attached to the Elekta Synergy linear accelerator. For this study, the dosimetric parameters including, Percent Depth Dose (PDD), Leaf leakage and penumbra, have been measured by using of the radiochromic films (GafChromic EBT2), EDGE diode detector and three-dimensional water phantom. All datas were measured on 6 MV x-ray. As a result, The DMLC shows transmission below to 1% and because of double-focused construction of the DMLC, the penumbras of fields with DMLC are independent from the field sizes. In this paper, the resulting dosimetric evaluations proved the applicability of the DMLC attached to the Elekta Synergy linear accelerator.

Effects of Covering Materials on Light Environment in Protected Horticulture (시설원예의 피복자재가 광환경에 미치는 영향)

  • 조일환;조삼증;김태영;허노열;권영삼
    • Proceedings of the Korean Society for Bio-Environment Control Conference
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    • 1997.05a
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    • pp.87-91
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    • 1997
  • 시설원예의 현대화에 따른 각종 피복자재의 도입ㆍ개발과 시설재배 면적의 급속한 증가로 인해 그에 따른 피복자재의 광환경 특성이 검토되지 않고 피복자재가 이용되고 있다. 따라서 본 연구는 연질필름중 가장 피복재배면적이 많은 PE(Polyethylene)필름과 경질판PC (Polycarbonate), PET (Poyethylene terephthalate), 유리 피복자재의 광환경 개선을 위한 기초 연구로 실시하였다. 1. 피복자재별 광투과율은 PE가 약 80%, 유리가 약 90%로, 유리 온실은 완공후 4년이하 경과했음에도 약 5개월 된 PE 보다 광투과율이 높았다. 2. 피복자재별 광반사율은 PE가 가장 높은 약 3% 였고 PC>PET>유리의 순으로 나타났다. 3. 피복자재별 광흡수율은 PE는 전파장에 걸쳐 고루 흡수되었으나 PC, PET는 자외선의 흡수가 많았다. 4. 피복자재별 토마토 군락내 광분포에서 제 1과방의 광량은 시설내 투과일사의 약 15%정도였다. 5. 피복자재별 토마토엽의 증산속도는 PE가 다소 낮았으나 처리간 큰 차이는 없었다. 6. 수경재배의 토마토의 광합성속도가 토경재배 보다 낮았다.

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Physiological Study for Dense Planting and Early High Yielding Potential of New Korean Dwarf Yuzu (Citrus junos Sieb. Ex Tanaka) (신육성 왜성 한국유자 (Citrus junos)의 밀식재배 및 조기 다수확을 위한 생리적 연구)

  • 송원섭
    • Korean Journal of Plant Resources
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    • v.8 no.3
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    • pp.265-274
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    • 1995
  • Characteristics of vegetative spur leaf, spur bud, fruiting supr leaf and flowering in relation to canopy position was investigated on order to promote better spur bud and flower bud differentiation on Citrus junos. There was no difference in vegetative spur leaf characteristics among directions. Vegetative spur leaf number and leaf area showed no difference between top and bottom position. There was no difference in spur bud size among directions, but spur bud at top was larger than that at bottom. Specific leaf weight of vegetative spur was mostly influenced by light interception, and leaf dry weight per spur average leaf dry weight, spur bud length and diameter had also a very high correlation with light interception rate. Shading and GA treatment in spur bud and flower bud differentiation was ineffective than natural light. Fruit thinning enhanced fruit quality as well as flower bud differentiation through an increase of leaf number per fruit, over 40 in Citrus junos.

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Identification of Regenerable Cells in MesophyII Protoplast Cultures (엽조직에서 나출된 원형질체의 재생 가능 세포판별)

  • 소인섭;유장걸
    • Korean Journal of Plant Tissue Culture
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    • v.21 no.1
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    • pp.23-28
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    • 1994
  • This study was rimed out to examine the difference in the cell vitality between mesophyII protoplast (MP) and paraveinal mesophyII protoplast (PVMP) of Nicotiana tabaccum 'Xanti', Petunia hybrida 'Blue Star' and Chrysanthemum morifolium 'Baeckwang' by using urea permeability technique. The effects of various enzyme solutions and incubation time, NAA and thidiazron on plant regeneration from isolated protoplasts were also investigated. The vibratome technique was used for protoplast isolation and urea permeability test because the fresh living, thin tissue stripes (50 ${\mu}{\textrm}{m}$ of thickness) could be obtained with minimal damage with the vibratome. For the three plants examined, the urea permeability on the tested tissue stripes was relatively higher in PVMP than in MP by about Ks = 2.0 $\times$ 10$^{-5}$ cm/sec. The treatment of an enzyme mixture of 1.5% cellulase R-10, 1% Driselase, 0.5% Macerozyme R-10, and 0.5% Pectinase for 4 to 8 h was effective on the isolation of PVMP. The highest frequency of callus formation and plant regeneration from the isolated protoplasts was obtained with NAA 2 mg/L and thidiazuron 0.01 mg/L. Furthermore, the results demonstrated that cell devision and plantlet regeneration was more frequent in the PVMP than in the MP of the same leaf or plant We, therefore, conclude that UM is an excellent experimental material for the callus formation and regeneration from isolated protoplasts.

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A Case of Posterior Reversible Encephalopathy Syndrome during Cyclosporine Therapy in a Child with Steroid Resistant Nephrotic Syndrome (스테로이드 저항성 신증후군 환아에서 사이클로스포린 투여 중 발생한 후두엽 가역성 뇌병증 증후군 1례)

  • Jeong, Min-Hee;Lee, Joo-Hoon;Yum, Mi-Sun;Ko, Tae-Sung;Park, Young-Seo
    • Childhood Kidney Diseases
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    • v.11 no.1
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    • pp.92-99
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    • 2007
  • The posterior reversible encephalopathy syndrome(PRES) is characterized clinically by a combination of acute or subacute confusion, lethargy, visual disturbance, and seizures. PRES has been described in various clinical settings, including severe hypertension, chemotherapy, eclampsia, and seizure. We report a case of a 7-year-old girl who had taken cyclosporine for steroid resistant nephrotic syndrome. Twenty one days after the cyclosporine therapy, she was admitted due to generalized tonic clonic seizure and headache. Her blood pressure was 170/90 mmHg. Magnetic resonance(MR) imaging showed necrotic/cystic lesions involving the bilateral parieto-occipital region. After discontinuation of cyclosporine, and control of blood pressure, she had no more seizure and headache. The follow-up MR examination which was performed 6 months later showed the decreased extent of the lesion.

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Occurrence of Sesame Phyllody Disease in Korea and Detection of Its Phytoplasma (참깨 엽화병의 발생과 파이토플라스마의 검출)

  • Han, Mu-Seok;Noh, Eun-Woon;Yun, Jeong-Koo
    • Korean Journal Plant Pathology
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    • v.13 no.4
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    • pp.239-243
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    • 1997
  • In August 1996, phyllody disease of sesame (Sesamum indicum L.) caused by phytoplasmas was observed at Boeun, Chungbuk Province, Korea. Symptoms included extreme proliferation of growing tips and numerous small leaves, giving the infected plant a witche's-broom effect. Parts or all of the floral parts were transformed into green leaf-like structures, and little or no seeds were produced. Transmission Electron microscopy revealed the presence of phytoplasmas in the phloem sieve elements of infected plant. Since the infected sesame plants were growing near by phytoplasma infected jujubes (Zizyphus jujubu), we tried a polymerase chain reaction (PCR) technique to identify these two causal phytoplasmas. The DNA extracted from the stems of infected sesame plant was PCR-amplified using a primer set specific to 16S rRNA gene of known phytoplasmas. The amplification generated a 1.4kb band in both sesame samples and phytoplasma-infected jujubes, which also suggests the sesame plants were infected with phytoplasmas. The restriction digestion of the amplified band by four different enzymes, AluI, HaeIII, HinfI or TaqI revealed that the phytoplasmas infecting jujubes and sesame plants were of different groups.

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