• Tuberculosis and Respiratory Diseases
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• v.59 no.1
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• pp.30-38
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• 2005

Background : Arsenic trioxide ($As_2O_3$) has been used to treat acute promyelocytic leukemia, and it induces apoptosis in a variety of solid tumor cell lines including non-small cell lung cancer cells. However, nonsteroidal antiinflammatory drugs (NSAID) can enhance tumor response to chemotherapeutic drugs or radiation. It was previously demonstrated that a combination treatment with $As_2O_3$ and sulindac induces the apoptosis of NCI-H157 human lung carcinoma cells by activating the caspase cascade. This study aimed to determine if a combination treatment augmented its apoptotic potential through other pathways except for the activation of the caspase cascade. Material and Methods : The NCI-H157 cells were treated with $As_2O_3$, sulindac and antioxidants such as glutathione (GSH) and N-acetylcysteine (NAC). The cell viability was measured by a MTT assay, and the level of intracellular hydrogen peroxide ($H_2O_2$) generation was monitored fluorimetrically using a scopoletin-horse radish peroxidase (HRP) assay. Western blotting and mitochondrial membrane potential transition analysis were performed in order to define the mechanical basis of apoptosis. Results : The viability of the cells was decreased by a combination treatment of $As_2O_3$ and sulindac, and the cells were protected using antioxidants in a dose-dependent manner. The increased $H_2O_2$ generation by the combination treatment was inhibited by antioxidants. The combination treatment induced changes in the mitochondrial transmembrane potential as well as the expression of the Bcl-2 family proteins, and increased cytochrome c release into the cytosol. However, the antioxidants inhibited the effects of the combination treatment. Conclusion : Combination treatment with $As_2O_3$ and sulindac induces apoptosis in NCI-H157 human lung carcinoma cells via ROS generation with a mitochondrial dysfunction.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2011.03a
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• pp.55-55
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• 2011

실리카 지지체 위에 은 (silver) 나노 입자를 부착시키는 방법으로는 지지체 표면을 먼저 은입자와 친화성이 큰 amino(-NH2), mercapto(-SH), cyan(-CN) 등의 관능기로 표면처리 하는 방법이 일반적으로 사용된다. 구체적으로 설명하면 첫 단계로 지지체인 실리카입자의 표면을 아민으로 표면 처리 한다. 실리카 입자위에 부착된 아민관능기는 입자 생성의 단계에서 은 (silver) 나노 입자가 붙는 접촉점의 역할과 핵 생성 장소로서의 역할을 하게되고, 아민 관능기의 이런 역할로 실리카 입자 표면에 부착된 핵이 생장하여 입자가 됨으로써 최종적으로 은(silver) 나노 입자가 실리카 지지체위에 부착된 형태의 나노복합체가 형성된다. 분자량이 다른 PVP를 사용하여 제조한, NH2와 SH로 계면처리 된 은-실리카 나노복합체제조를 시도하였다. 사용되는 PVP의 분자량이 증가함에 따라 긴 고분자 사슬에 의하여 생성된 입체장애가 증가하게 되어, 은 핵의 성장에 대한 물리적 장벽이 증가하게 된다. 그러므로 고정화된 은 입자의 크기가 감소하게 된다. 이러한 형상은 NH2기 또는 SH기로 계면 처리된 실리카를 이용하여 제조된 은-실리카 나노복합체 입자들에서 모두 관찰되지만, SH기로 계면처리된 실리카를 사용할 경우 고정화된 은 입자의 수가 더욱 많고, 크기 역시 더욱 균일함을 알 수 있다.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.73-73
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• 2012

본 연구에서는 리싸이클 방법에 따른 리싸이클 폴리에스터사의 물리적 성질을 고찰하고자 하였다. 시료로는 물리적 리싸이클 방법과 화학적 해중합을 통한 리싸이클 방법을 사용한 폴리에스터사를 사용하였다. 리싸이클 폴리에스터사의 표면 형상을 관찰하기 위해 SEM을 이용하였고, 열적 거동을 규명하기 위해 DSC를 이용하였으며, 미세 구조적 차이를 살펴보기 위해 XRD 분석을 하였고, 역학적 성질을 평가하기 위해 인장강도와 절단신도를 측정하였다. 연구 결과, 리싸이클 방법에 따라 Tg, 결정화 온도, 융점과 융해열은 약간의 차이를 보였다. 화학적 리싸이클 PET사는 Virgin PET사보다 Tg가 약간 상승하였고, 승온 시 결정화 온도는 하강하였으며, 융점의 차이는 거의 없는 것으로 나타났다. 이는 해중합에 의해 PET의 비결정영역의 고분자 사슬 간의 거리가 좁아져 더 높은 Tg를 나타내는 것으로 생각된다. 또한, 물리적 리싸이클 PET사의 융점과 융해열은 화학적 리싸이클 PET사의 융점과 융해열보다 더 높게 나타났다. 결정화도에서는 리싸이클 방법에 따른 차이는 거의 보이지 않았다. 이는 리싸이클 공정이 폴리에스터의 결정영역 변화에는 유의한 영향을 미치지 않았기 때문인 것으로 생각된다. 실의 인장강도는 리싸이클 PET사는 virgin PET사보다 약간 더 낮았고, 물리적 리싸이클 PET사와 화학적 리싸이클 PET사는 비슷하게 나타났고, 절단신도는 virgin PET사, 물리적 리싸이클 PET사와 화학적 리싸이클 PET사 간의 뚜렷한 차이는 없는 것으로 나타났다.

• Textile Coloration and Finishing
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• v.30 no.2
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• pp.77-89
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• 2018

In the case of fiber/rubber composites for tire applications, the interfacial adhesion between fiber and rubber significantly affects the physical properties of the finished products. Generally, organic synthetic fibers used for tire cords are treated with resorcinol formaldehyde latex(RFL) primer on the surface of the fiber to improve the adhesion to rubber. Changes of adhesion between rubber and tire cords might weaken as temperature rises due to overheating of car engine and friction with road. In this study, the effects of temperature on the primer treated polyketone cord/rubber composites and the changes in interfacial adhesion were investigated. Polyketone cord/rubber composites were prepared after RFL solution treatment on the surface of polyketone fibers. After that, composites was thermally aged at different temperature conditions(60, 80, 100, $120^{\circ}C$) and times(1, 5, 10, 15days). The adhesion strength of polyketone cord/rubber composite treated with RFL primer was higher than untreated composite by more than 3 times. After heat aging, the adhesion strength of untreated polyketone cord/rubber composites increased while the RFL treated polyketone cord/rubber composites decreased somewhat.

• Journal of the Korean Society of Clothing and Textiles
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• v.25 no.5
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• pp.891-900
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• 2001

The purpose of this study were to evaluate the physical properties and dyeability of cellulase and alkali(NaOH, KOH) treated ramie/man-made fiber mixture fabrics. The mixture fabrics were plain weave made by rayon and polyester fiber as warp yarn, and ramie as weft yarn. The crease resistance, drape, tensile strength, and water absorbancy were measured for test fabrics. The K/S value of dyed fabrics were calculated using color difference meter. Also colorfastness to washing and sunlight of dyed fabrics were evaluated. The results obtained from this study were as follows: Thickness and weight per unit area of alkali treated two mixture fabrics(rayon/ramie, polyester/ramie) increased compared to those of untreated fabrics, but cellulase treated fabrics did not changed a little. And alkali treated rayon/ramie mixture fabrics showed more change than polyester/ramie mixture fabrics on the thickness and weight. Tensile strength and water absorbancy of cellulase treated fabrics decreased compared to those of untreated, but crease resistance increased. Crease resistance, tensile strength(warp direction), water absorbancy and drape of NaOH treated rayon/ramie mixture fabrics decreased compared to those of untreated, but tensile strength(weft direction) increased. Water absorbancy and drape of NaOH treated polyester/ramie mixture fabrics decreased compared to those of untreated, but crease resistance and tensile strength(weft direction) increased. Tensile strength of KOH treated two mixture fabrics increased compared to that of untreated, but water absorbancy and drape decreased. Total hand of cellulase and alkali treated rayon/ramie mixture fabrics was improved compared to untreated. Dyeability of treated mixture fabrics was increased compared to untreated.

• The Research Journal of the Costume Culture
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• v.13 no.2 s.55
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• pp.240-247
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• 2005

In this study, cotton fabric specimens were pre-mordanted using Sn, Al, Cu, Cr, and Fe, and subsequently dyed using cochineal, maintaining the pH of the dye bath constant using pH buffer solutions of 4, 5, 6, 7, and 8. In the cases of Al, Cr, and Sn mordanting, the dye-uptake was well accomplished in the acidic range of pH 4 and 5. However, the dye-uptake was not accomplished in the range over pH 6. In the cases of Cu and Fe mordanting, however, the pH value did not affect the dye-uptake and the dyeability in the alkaline range was not decreased remarkably. In the case of non-mordant, the dye-uptake was not accomplished at all, and the Cu and Fe mordanting gave rise to the best dyeability. In the cases of non-mordanting and Al, Cu mordanting, there was no change in the $\lambda_{max}$, and in the cases of Sn and Cr mordanting, the $\lambda_{max}$ moved toward the shorter wavelength. In the case of Fe mordanting only, the $\lambda_{max}$ moved gradually toward the longer wavelength, and due to the pH effect deep-dyeing effect was revealed.

• Textile Coloration and Finishing
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• v.34 no.3
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• pp.207-216
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• 2022

Hydrogels have gained considerable attention in various fields due to their easily transformative ability by different stimulation. In addition, metal-based conductive additives can enable the hydrogels to be conductive with dimension change. Although the development of the additives offered enhanced electrical properties to the hydrogels, correspondingly enhanced mechanical properties may limit the volume and electrical properties switching after stimulation. Here we prepared poly(N-isopropylacrylamide) (PNIPAM) thermo-responsive hydrogel that has a 32℃ of low critical solution temperature and added liquid metal particles (LMPs) as conductive additives, possessing soft and stretchable benefits. The LMPs enabled PNIPAM (PNIPAM/LMPs) hydrogels to be constricted over 32℃ with a high volume switching ratio of 15.2 when deswelled. Once the LMPs are spontaneously oxidized in hydrogel culture, the LMPs can release gallium ions into the hydrogel nature. The released gallium ions and oxidized LMPs enhanced the modulus of the PNIPAM/LMPs hydrogel, triggering high mechanical stability during repeated swelling/deswelling behavior. Lastly, highly constricted PNIPAM/LMPs hydrogel provided a 5x10⁶ of electrical switching after deswelling, and the switching ratio was closely maintained after repeated swelling/deswelling transformation. This study opens up opportunities for hydrogel use requiring thermo-responsive and high electrical switching fields.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.62-62
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• 2012

지구온난화 및 환경오염의 영향으로 선진국을 중심으로한 환경규제가 심해지면서, 홈 텍스타일 분야에서는 세계 패션 트렌드 및 소비자 선호에 부응한 친환경 섬유소재 개발, 웰빙 시대에 적합한 기능성 및 고감성 제품개발을 통한 차별화가 요구되고 있다. 최근의 섬유산업의 동향도 인체에 무해한 천연적인 섬유소재에 많은 관심이 증대됨에 따라 개인의 건강 뿐만 아니라 환경을 생각하는 생활패턴인 친환경섬유의 개발이 새로운 트렌드로 떠오르고 있는 실정이다. 헴프는 일년생 식물로서 학명은 Cannabis sativa L.이다. 헴프섬유의 장점으로 내구성 및 내수성, 항균성 등이 우수한 것으로 보고되고 있으나 양질의 원료 확보, 세섬도 추출 기술 및 combing 기술 등의 부족으로 100% 헴프 세 번수 방적사의 제조가 어려워 주로 면섬유와의 혼합소재로 제조되어 왔다. 최근 들어, 친환경 소재로서 박테리아 성장 억제 기능을 가진 재생섬유인 Tencel 소재를 이용하여 stiff한 Hemp의 성질에 유연성을 추가하여 촉감을 개선함과 동시에, Tencel과 Hemp를 혼용함으로써 soft touch부터 harsh touch까지 혼용율에 의한 다양한 감성을 느끼게 함으로써 용도의 다양화 추구가 시도되어 왔다. Hemp의 거친 느낌을 완화시키고 Tencel의 박테리아 억제 기능과 Hemp의 항균기능, 방충, 탈취기능이 상호 보완되어 친환경적이고 위생적인 다용도 홈 인테리어 및 가구용 직물 등의 제품으로 Hemp/Tencel 복합사가 많이 사용되고 있다. 본 연구는 Hemp와 Tencel의 혼용율의 변화에 따른 복합사의 물리적 특성을 확인하기 위하여 천연복합 태번수 방적사 최적 사설계 이론을 적용하여 Hemp 섬유 혼용율에 따른 사의 물성분석을 함으로써 Hemp/Tencel 방적사 최적 공정 조건을 결정하기 위한 사설계 이론 결과와 실험결과를 비교 분석하고자 한다. 최적 천연 Hemp복합방적사 사설계의 이론화 및 사 물성 DB화 그리고 태번수 Hemp사의 물성분석 및 이들을 DB화 함으로써 가구용 직물로 많이 사용되는 친환경 Hemp 소재사의 방적성 향상을 꾀하고자 한다. 이를 위해서 제조한 방적사의 Dry heat shrinkage와 Wet heat shrinkage를 측정하여 확인하였고 인장시험기를 이용하여 Tenacity, Initial Modulus, breaking strain을 측정 분석하였다. 방적사의 표면 특성은 영상 현미경 시스템을 사용하여 ${\times}40$ 배율로 측정하여 확인하였다.

• Journal of Chest Surgery
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• v.39 no.2 s.259
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• pp.166-170
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• 2006

Myxofibrosarcoma represents one of the most common soft tissue sarcomas of the extremities in adult and elderly patients. However, it only rarely occurs in the chest wall. A 58 years old woman presented with a huge painless lump (8 ${\times}$ 6.5 cm) in the right lower parasternal area which recurred a few months following excision from General surgery of our hospital. Histology showed an infiltrative deep seated dermal and subcutaneous tumor. It had a distinctive lobular growth pattern with prominent myxoid change and moderate cellularity. Tumor cells were spindleshaped with varying degrees of pleomorphism and frequent mitotic figures. Numerous blood vessels with curvilinear growth pattern were also seen. Immunostains for S-100, CD68, Mac 387, and FX IIIa were all negative, but positive for Vimentin. The histologic feature was of an intermediate grade myxofibrosarcoma. Wide excision was performed and recovered in good condition without any physical disabilities and was discharged at one month later. Currently she is waiting for the skin graft without chemotherapy and radiotherapy.

• Journal of the Korean Geotechnical Society
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• v.21 no.4
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• pp.65-70
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• 2005

Many case histories of re-liquefaction phenomena seem to support the idea that sand deposits, if they once have been liquefied, could be reliquefied again by a subsequent earthquake even though the earthquake is smaller than the previous one. The magnitude of the strains induced in the initial liquefaction has a significant influence on the resistance of the sample to re-liquefaction. The deposits undergoing liquefaction experience large shear strain during liquefaction. And this previous strain changes the microstructure into highly anisotropic structure such as columnlike structure and connected voids. This type of anisotropy is so unstable that it can reduce re-liquefaction resistance. It is blown that the extent of anisotropic structural change depends on the gradation characteristics of ground. The purpose of this study is to estimate the correlation between the gradation characteristics of the sand and the ratio of re-liquefaction resistance to liquefaction resistance. In this study, 1-g shaking table tests were carried out on five different kinds of sands. During the tests the values of excess pore pressure at various depths and surface settlements were measured. Re-liquefaction resistances were not affected by the initial void ratio and the effective confining pressures, and the deposits of all test sands which had once been liquefied were reliquefied in the cyclic loading number below 1 to 1.5. The ratio of re-liquefaction resistance to liquefaction resistance linearly decreased as $D_{10}/C_u$ increased, and was constant as about 0.2 above the value of $D_{10}/C_u$, 0.15 mm.