• Applied Biological Chemistry
• /
• v.46 no.4
• /
• pp.361-366
• /
• 2003

Anti-aflatoxigenic studies on synthetic pyridione alkaloids were conducted. Seven derivatives using piperlongumine as a leading compound were prepared from 3,4,5-trimethoxycinnamic acid (TMCA). These derivatives were analyzed for their structural confrmation and purity by HPLC, GC, GC/MS and $1^H-NMR$. 1-piperidin-1-yl-3-(3,4,5-trimethoxyphenyl)propenone (1) reaction with piperidine; 1-morpholin-4-yl-3-(3,4,5-trimethoypenyl)propenone (2) with morpholine; 1-(3,5-dimethylpiperidin-1-yl)-3-(3,4,5-trimethoxyphenyl)propenone (3) with 3,5-dimethylpiperdine; 1-(2-methylpiperidine-1-yl)-3-(3,4,5-trimethoxyphenyl)propenone (4) with 2-methylpiperidine; 1-(3-hydroxypiperidin-1-yl)-3- (3,4,5-trimethoxyphenyl)propenone (5) with 3-hydroxypiperidine hydrochloride; 1-[3- (3,4,5-trimethoxyphenyl)acryloyl]piperidin-2-one (6) with ${\delta}-valerolactam;\; and\;ethyl\;1-[3-(3,4,5-trimethoxyphenyl)acyloyl]piperidine-4-carboxylate$ (7) with ethyl isonipectotate were synthesized respectively. All derivatives showed an inhibitory activity on aflatoxin $B_1$ production. In conclusion, we believe that they might be an agent for the control of mycotoxin in agricultural commodities.

• 한국신재생에너지학회:학술대회논문집
• /
• 2011.05a
• /
• pp.196.2-196.2
• /
• 2011

지구온난화와 화석연료 고갈에 대한 우려로 전세계적으로 신재생에너지의 개발 및 활용이 본격화되고 있다. 특히, 다양한 신재생에너지원 중에서 날씨 및 계절에 의한 영향, 기저부하 담당, 지상 점유 면적, 소음 등 생활환경 영향, 경제성 등을 고려할 때 지열에너지는 미래 청정에너지원로서 기대와 관심이 집중되고 있다. 화산이 존재하지 않는 우리나라에서의 지열발전은 거의 불가능한 것으로 인식되어 지금까지의 심부 지열에너지 개발 프로젝트는 대부분 지역난방, 시설영농 등 직접이용을 목표로 추진되어 왔다. 그러나, 2003년부터 한국지질자원연구원에서 수행한 포항 심부지열에너지 개발사업의 결과로 얻어진 다양한 지질학적/지열학적 증거들을 토대로 분석한 결과, 국내 일부 지역에서는 지하 5 km 심도에서 최대 약 $180^{\circ}C$의 지온이 예상되어 국내에서도 심부 지열에너지를 이용한 지열발전에 대한 가능성이 제기되어 왔다. 여기에, 유럽과 미국 그리고 호주 등 선진국을 중심으로 비화산 지역에서 지하 심부에 인공적으로 지열저류층(파쇄대)을 생성하고 이를 통해 열매체(물)를 순환시킴으로써 생산된 증기를 발전에 활용하는 EGS (Enhanced Geothermal System) 기술이 개발되고 몇몇 성공사례가 발표되었다. 또한, 이러한 기술개발에 힘입어 EGS 지열발전에 대한 선진국의 과감한 연구비 투자가 이어졌다. 이러한 기술적 배경에 발맞추어 우리나라에서도 2010년 12월에 EGS 지열발전 과제가 착수되었다. 이 프로젝트는 아시아에서는 최초로 수행되는 EGS 기술 개발과제로서 2015년까지 약 480억원의 R&D 예산을 투입하여 MW급의 지열발전 pilot plant의 구축을 목표로 하고 있다. 프로젝트가 성공적으로 추진될 경우 국내외적인 파급효과는 매우 클것이다. 특히 2015년까지 1.5 MW의 pilot plant의 구축이 성공적으로 추진될 경우 국내에서는 2017년까지 3 MW 이상, 2020년까지 20 MW이상, 2030년까지 200 MW 이상의 지열발전이 가능할 것으로 기대된다. 또한 축적된 기술개발 경험을 바탕으로 인도네시아, 필리핀 등의 해외의 지열발전 사업에도 진출할 수 있는 계기가 될 것이다. 프로젝트는 넥스지오를 주관기관으로 하고 한국지질자원연구원, 한국건설기술연구원 및 서울대학교 등의 지질자원 관련 연구 및 교육기관과 포스코, 이노지오테크놀로지 등의 산업체가 참여하여 컨소시엄 형태로 추진하고 있으며, 향후 관심있는 여러 기관 및 산업체의 지원과 참여를 기대한다.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.34 no.9
• /
• pp.1241-1248
• /
• 2010

In large-scale production of hydrogen, a PHE (Process Heat Exchanger) is a key component because the heat required to carry out the Sulfur-Iodine chemical reaction that yields hydrogen is transferred from a VHTR (Very High Temperature Reactor) by the PHE. Korea Atomic Energy Research Institute established a helium gas loop for conducting performance test of components that are used in the VHTR. In this study, as a part of high-temperature structural-integrity evaluation of a designed PHE prototype that is scheduled to be tested in the helium gas loop, we carried out high-temperature structural-analysis modeling, thermal analysis, and thermal-expansion analysis for the designed PHE prototype. An appropriate constraint condition is proposed at the end of the in-flow and out-flow pipelines of the primary and secondary coolants and the proposed constraint condition will be applied to the design of the performance-test loop setup for the designed PHE prototype.

• Applied Biological Chemistry
• /
• v.43 no.1
• /
• pp.72-77
• /
• 2000

The repeated silica gel colum chromatographies of EtOAc fraction, showing anticonvulsant activity, obtained from MeOH extracts of Schizandra chinensis B. fruits led to isolation of a sesquiterpenoid, four lignans and a sterol glycoside. Their chemical structures were determined to be chamigrenal, gomisin A, gomisin H, gomisin N. schizandrin and daucosterol. Among them, schizandrin and daucosterol inhibited GABA degrative enzymes, succinic semialdehyde dehydrogenase and succinic semialdehyde reductase, respectively. It is postulated that the schizandrin and daucosterol are able to elevate the neurotransmitter GABA levels in central nervous system by inhibitory action on GABA degrative enzymes and act as anticonvulsant drugs.

• Korean Journal of Environmental Agriculture
• /
• v.16 no.4
• /
• pp.304-310
• /
• 1997

In greenhouse, a mixed solution of Mn-54, Co-60, Sr-85 and Cs-137 was applied to the soil of culture boxes 2 days before sowing cucumber and at 4 different times during its growth for measuring their transfer factors (TFs) for fruit and migration in soil. TFs varied with radionuclide, application time and harvest time by factor of up to about 60. Variations in TFs with application time showed different patterns among radionuclides. TFs decreased on the whole in the order of Sr-85 > Mn-54 > Co-60 > Cs-137. TFs of Mn-54, Co-60 and Cs-137 mixed with topsoil before sowing were a little higher than those for the soil-surface application made at an early growth stage while no difference in Sr-85 TF was found. After harvest, soil concentrations of the radionuclides applied at an early growth stage were examined. They decreased with increasing soil depth and 80${\sim}$99% of the radioactivity remained in the top 3cm. Soil pemeation of the radionuclides migration decreased in the order of Sr-85 > Mn-54 > Co-60 > Cs-137. The present data can be utilized in estimating radionuclide concentration in cucumber fruit, taking proper measures for its harvest and consumption and designing the best way of soil decontamination following an radioactive deposition during the cucummber growing season.

• Journal of Biosystems Engineering
• /
• v.9 no.2
• /
• pp.74-80
• /
• 1984

Storage materials for a minimized storage system should be able to store much energy in small quantities, and to solve such a problem, salt hydrates such as CALCIUM CHLORIDE, SODIUM SULFATE, SODIUM PHOSPHATE etc. were considered as most suitable storage media in which phase change phenomena take place at low temperature. Therefore those salt hydrates were used as storage media in this study, and piped-storage tanks were manufactured vertically for the experiment. The characteristics of thermal storage media were investigated and the results are summarized as follows: 1. From the experiment of radial temperature distribution of vertical piped-storage system, the latent heat phenomenon did not occur in all storage media during heating process because of generations of heat due to the reduction in the number of water molecules. However, among those storage media CALCIUM CHLORIDE had most remarkable latent heat phenomenon during cooling process. Therefore CALCIUM CHLORIDE was considered as most suitable storage media. 2. Heat quantity transferred to the storage media was the largest in case of CALCIUM CHOLORIDE under the same conditions during heating and cooling process.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.3
• /
• pp.35-42
• /
• 2019

Risk assessment and analysis for a medium-to-small sized chemical plant that manufactures a polyester resin by the process of batch-type condensation reaction was conducted using K-PSR technique which is one of the risk assessment methods used to implement the Process Safety Management System (PSM). K-PSR is a risk assessment technique developed by KOSHA to compensate for difficulties caused by the lack of infrastructure of medium-to-small sized chemical plants in the re-evaluation. To apply the K-PSR technique, the entire process of a selected chemical palnt was classified in two review sections, i.e., the condensation reaction process and the dilution/filtration process, and the potential risks of the process about these review sections were identified and classified based on the four guide-words (release, fire.explosion, process trouble, and injury). As the results of the research, refer to recommend of risk rating has been confirmed that non-destructive testing of old facilities and the preparation of LOTO procedures for the electrical equipments are necessary as specific measures to prevent the risk of release and fire.explosion. It was also shown that pressure gauges and thermometers should be installed on the hot-oil supply piping to minimize the process trouble, and exhausting hood should be installed to prevent potential injury.

• Clean Technology
• /
• v.29 no.3
• /
• pp.185-192
• /
• 2023

This study was conducted to obtain basic process simulation data before conducting pyrolysis experiments for the development of a thermochemical conversion system by recirculation of heat carrier and gases thereby. In this study, polypropylene (PP) was used as a pyrolysis sample material as an alternative to waste plastics, and fluid sand was used as a heat transfer medium in the system. Manganese (Mn) was chosen as the catalyst for the pyrolysis experiment, and the catalyst pyrolysis was performed by impregnating it in the sand. The basic properties of PP were analyzed using a thermogravimetric analyzer (TGA), and liquid oil was generated through catalytic pyrolysis under a nitrogen atmosphere at 600℃. The carbon number distribution of the generated liquid oil was confirmed by GC/MS analysis. In this study, the effects of the presence and the amount of Mn loading on the yield of liquid oil and the distribution of hydrocarbons in the oil were investigated. When Mn/sand was used, the residue decreased and the oil yield increased compared to pyrolysis using sand alone. In addition, as the Mn loading increased, the ratio of C₆~C₉ range gasoline in the liquid oil gradually increased, and the distribution of diesel and heavy oil with more carbon atoms than C₁₀ in the oil decreased. In conclusion, it was found that using Mn as a catalyst and changing the amount of Mn could increase the yield of liquid oil and increase the gasoline ratio in the product.

• Journal of Plant Biotechnology
• /
• v.43 no.3
• /
• pp.261-271
• /
• 2016

Citrus is an economically important fruit crop widely growing worldwide. However, citrus production largely depends on natural hybrid selection and bud sport mutation. Unique botanical features including long juvenility, polyembryony, and QTL that controls major agronomic traits can hinder the development of superior variety by conventional breeding. Diverse factors including drastic changes of citrus production environment due to global warming and changes in market trends require systematic molecular breeding program for early selection of elite candidates with target traits, sustainable production of high quality fruits, cultivar diversification, and cost-effective breeding. Since the construction of the first genetic linkage map using isozymes, citrus scientists have constructed linkage maps using various DNA-based markers and developed molecular markers related to biotic and abiotic stresses, polyembryony, fruit coloration, seedlessness, male sterility, acidless, morphology, fruit quality, seed number, yield, early fruit setting traits, and QTL mapping on genetic maps. Genes closely related to CTV resistance and flesh color have been cloned. SSR markers for identifying zygotic and nucellar individuals will contribute to cost-effective breeding. The two high quality citrus reference genomes recently released are being efficiently used for genomics-based molecular breeding such as construction of reference linkage/physical maps and comparative genome mapping. In the near future, the development of DNA molecular markers tightly linked to various agronomic traits and the cloning of useful and/or variant genes will be accelerated through comparative genome analysis using citrus core collection and genome-wide approaches such as genotyping-by-sequencing and genome wide association study.

• Korean Journal Plant Pathology
• /
• v.2 no.3
• /
• pp.185-192
• /
• 1986

Upon germination, a conidium was septated in accordance with number of germ tubes. The percentages of ppressorial formation were not different between the resistant cultivars (Kumchang NO. 2 and Hongilpum) and the susceptible cultivars (Haneulcho and Saegochu). Appressorial form was various such as round, elliptic or star-shapped. The maximum number of appressoria was shown at 12 hours after inoculation. By 24 hours fter inoculation, hypersensitive tiny brown lesions were observed on the leaves and fruits of the resistant cultivars. Epidermal cells under cuticle layer of the resistant Kumchang NO. 2 fruit showed severe plasmolysis, while on the susceptible cultivars, the lession was largely extended to following incubation. Subcuticular infection hyphae were profusely colonized in the disintegrated tissues. Acervuli and setae on the stromatic structure ere formed at 96 hours. The infected seed coat was not only severely collapsed, but also infection hyphae were observed on the disintegrated seed coat, resulting severe plasmolysis of nucellus and embryo.