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Tc-99m-DAPA Pulmonary Clearance in Normals (정상성인에서의 Tc-99m-DTPA 폐제거율)

  • Chung, Soo-Kyo;Yang, Woo-Jin;Sohn, Hyung-Sun;Shinn, Kyung-Sub;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.338-342
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    • 1994
  • Pulmonary clearance of Tc-99m-DTPA(PCD) has been used for the measurement of polmonary epithelial permeability. It has been reported to be increased not only in variety of polmonary diseases including ARDS, interstitial fibrosis, and smokers, but also in normal subjects on positive end expiratory pressure respirator, or after exercise. It was also noted that decrease of pulmonary blood flow due to pulmonary arterial obstruction results in delayed PCD. Normal range of PCD varies with institutes. We prospectively measured PCD in 17 normals (5 males and 12 females) consisted of staffs and trainees in the department of radiology of Kangnam St. Mary's hospital using original Bark Nebulizer (India). Age ranged from 32 to 43 years. 370 MBq of Tc-99m-DTPA was inhaled in supine position and supine posterior images were subsequently obtained with 1 min/frame, $64{\times}64$ matrix and word mode for 30min. Regions of interest were set on each lung, whole lungs, and upper, middle and lower thirds of right lung, respectively. Best fit regression curve was obtained by least square method from initial 7min after peak activity on each curve and time for half clearance of maximum activity (t1/2) was calculated. Mean t1/2 was $51{\pm}11.2min$ for whole lung. There was no significant difference between t1/ 2 of right and left lungs. Initial uptake was higher in the lower third and t1/2 was shorter in the lower third than in the upper third(P<0.05). We reviewed several reports on PCD and compared our data with the others. In this study, faster clearance in the lower third may be due to the position imaged with or the environment the subjects belong to, and further investigation is under way.

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Classification of Various Severe Hazes and Its Optical Properties in Korea for 2011~2013 (2011~2013년 한반도에서 관측된 다양한 연무의 분류 및 광학특성)

  • Lee, Kyu-Min;Eun, Seung-Hee;Kim, Byung-Gon;Zhang, Wenting;Park, Jin-Soo;Ahn, Jun-Young;Chung, Kyung-Won;Park, Il-Soo
    • Atmosphere
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    • v.27 no.2
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    • pp.225-233
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    • 2017
  • Korea has recently suffered from severe hazes, largely being long-range transported from China but frequently mixed with domestic pollution. It is important to identify the origin of the frequently-occurring hazes, which is however hard to clearly determine in a quantitative term. In this regard, we suggest a possible classification procedure of various hazes into long-range transported haze (LH), Yellow Sand (YS), and urban haze (UH), based on mass loading of fine particles, time lag of PM mass concentrations between two sites aligned with dominant wind direction, backward trajectory of air mass, and the mass ratio of PM2.5 to PM10. The analysis sites are Seoul (SL) and Baengnyeongdo (BN), which are distant about 200 km from each other in the west to east direction. Aerosol concentrations at BN are overall lower than those of SL, indicative of BN being a background site for SL. We found distinct time lag of PM2.5 and PM10 concentrations between BN and SL in case of both LH and YS, but the intensity of YS being stronger than LH. Time scale (e-folding time scale) of LH appears to be longer and more variable than YS, which implies that LH covers much larger spatial scale. In addition, we found linear and significant correlations between ${\tau}_a$ obtained from sunphotometer and ${\tau}_{cal}$ calculated from surface aerosol scattering coefficient for LH episodes, relative to few correlation between those for YS, which might be associated with transported height of YS being much higher than LH. Therefore surface PM concentrations for the YS period are thought to be not representative for vertical integrated amount of aerosol loadings, probably by virtue of decoupled structure of aerosol vertical distribution. Improvement of various hazes classification based on the current result would provide the public as well as researchers with more accurate information of LH, UH, and YS, in terms of temporal scale, size, vertical distribution of aerosols, etc.

An Analysis of Global Solar Radiation using the GWNU Solar Radiation Model and Automated Total Cloud Cover Instrument in Gangneung Region (강릉 지역에서 자동 전운량 장비와 GWNU 태양 복사 모델을 이용한 지표면 일사량 분석)

  • Park, Hye-In;Zo, Il-Sung;Kim, Bu-Yo;Jee, Joon-Bum;Lee, Kyu-Tae
    • Journal of the Korean earth science society
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    • v.38 no.2
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    • pp.129-140
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    • 2017
  • Global solar radiation was calculated in this research using ground-base measurement data, meteorological satellite data, and GWNU (Gangneung-Wonju National University) solar radiation model. We also analyzed the accuracy of the GWNU model by comparing the observed solar radiation according to the total cloud cover. Our research was based on the global solar radiation of the GWNU radiation site in 2012, observation data such as temperature and pressure, humidity, aerosol, total ozone amount data from the Ozone Monitoring Instrument (OMI) sensor, and Skyview data used for evaluation of cloud mask and total cloud cover. On a clear day when the total cloud cover was 0 tenth, the calculated global solar radiations using the GWNU model had a high correlation coefficient of 0.98 compared with the observed solar radiation, but root mean square error (RMSE) was relatively high, i.e., $36.62Wm^{-2}$. The Skyview equipment was unable to determine the meteorological condition such as thin clouds, mist, and haze. On a cloudy day, regression equations were used for the radiation model to correct the effect of clouds. The correlation coefficient was 0.92, but the RMSE was high, i.e., $99.50Wm^{-2}$. For more accurate analysis, additional analysis of various elements including shielding of the direct radiation component and cloud optical thickness is required. The results of this study can be useful in the area where the global solar radiation is not observed by calculating the global solar radiation per minute or time.

The Corrosion Behavior of Cold-Rolled 304 Stainless Steel In Salt Spray Environments (염분분사환경에서 냉연 304 스테인레스강의 부식거동)

  • Chiang, M.F.;Young, M.C.;Huang, J.Y.
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.9 no.2
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    • pp.93-98
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    • 2011
  • Saline corrosion is one of the major degradation mechanisms for stainless steel type 304 (SS304) dry storage cask during the spent fuel interim storage period. Slow strain rate test (SSRT) and neutral salt spray test (NSS) were performed at $85^{\circ}C$ and $200^{\circ}C$ with 0.5 wt% sodium chloride mist sprayed on the cold-rolled SS304 specimens of different degrees of reduction in this study. The weight changes of the NSS specimens tested at $85^{\circ}C$ for 2000 hours differed greatly from those at $200^{\circ}C$. The weight loss of NSS specimens was not significant at $85^{\circ}C$ but the weight gain decreased gradually with increasing the cold-rolled reduction. The yield strength (YS) and ultimate tensile stress (UTS) values obtained from the SSRT tests for lightly cold-rolled specimens in the salt spray environment at $85^{\circ}C$ and $200^{\circ}C$ are slightly lower than in air. But for those with 20% reductions, the specimen strengths were no longer changed by the saline corrosion. The preliminary results demonstrated that the quality and performance of cold-rolled SS304 is acceptable for fabrication of dry storage casks. However, more work on the corrosion behavior of cold-rolled stainless steel in the saline atmosphere is needed to better understand its long-term performance.

Seasonal occurrence of mushroom fly infestation and analysis of the effects of preemptive pest control technology: A case study in button mushroom farms in Buyeo County (부여지역 양송이농가 버섯파리 발생소장 및 사전방제기술 적용효과)

  • Hye-Sung Park;Seong-Yeon Jo;Tai Moon Ha
    • Journal of Mushroom
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    • v.21 no.4
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    • pp.266-269
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    • 2023
  • This study aimed to address the increasing demand for technologies preventing mushroom fly damage. By monitoring the annual occurrence patterns of pests over several years and accumulating data, we conducted an analysis to evaluate the efficacy of preventive measures applied before the surge in mushroom fly infestation, typically observed in May. For preemptive control, physical measures involved installing air curtains at cultivation facility entrances and placing sticky traps and insect traps around entry points to block external entry and reduce internal insect density. Additionally, we applied an organic agricultural material, Dalmatian chrysanthemum extract, weekly alongside chemical control measures. To assess the reduction in mushroom fly populations, yellow sticky traps (15×25 cm) were placed at three locations within the mushroom cultivation facility, and the occurrence patterns before and after implementing preventive measures were compared. Compared to conventional practices, the application of preventive techniques resulted in a significant reduction, with a 60% decrease from 15 levels of mushroom flies/m2 to 6 levels of mushroom flies/m2 in May and a 40% decrease from 10 levels of mushroom flies/m2 to 6 levels of mushroom flies/m2 in June. While achieving over 50% efficacy during the peak mushroom fly season with preventive measures, we identified complementary actions such as blocking external sources (gaps in cultivation facility doors) and maintaining cleanliness around cultivation facilities (proper disposal of spent substrate) for further improvement. Comprehensive analysis and safety studies, including correlation analysis with contaminants and pathogens, are recommended to ensure the widespread adoption of mushroom fly preventive techniques for safe and stable mushroom production in the agricultural sector.

Research on APC Verification for Disaster Victims and Vulnerable Facilities (재난약자 및 취약시설에 대한 APC실증에 관한 연구)

  • Seungyong Kim;Incheol Hwang;Dongsik Kim;Jungjae Shin;Seunggap Yong
    • Journal of the Society of Disaster Information
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    • v.20 no.1
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    • pp.199-205
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    • 2024
  • Purpose: This study aims to improve the recognition rate of Auto People Counting (APC) in accurately identifying and providing information on remaining evacuees in disaster-vulnerable facilities such as nursing homes to firefighting and other response agencies in the event of a disaster. Methods: In this study, a baseline model was established using CNN (Convolutional Neural Network) models to improve the algorithm for recognizing images of incoming and outgoing individuals through cameras installed in actual disaster-vulnerable facilities operating APC systems. Various algorithms were analyzed, and the top seven candidates were selected. The research was conducted by utilizing transfer learning models to select the optimal algorithm with the best performance. Results: Experiment results confirmed the precision and recall of Densenet201 and Resnet152v2 models, which exhibited the best performance in terms of time and accuracy. It was observed that both models demonstrated 100% accuracy for all labels, with Densenet201 model showing superior performance. Conclusion: The optimal algorithm applicable to APC among various artificial intelligence algorithms was selected. Further research on algorithm analysis and learning is required to accurately identify the incoming and outgoing individuals in disaster-vulnerable facilities in various disaster situations such as emergencies in the future.

The Statistical Identification of Airmass Characteristics during the Manna Loa Observatory Photochemistry Experiment (Mauna Loa (Hawaii)에서 관측된 대기질 특성의 통계적 분석)

  • Lee, Gang-Woong;Barry J. Huebert
    • Journal of Korean Society for Atmospheric Environment
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    • v.10 no.E
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    • pp.332-342
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    • 1994
  • Hierarchical cluster and factor analyses were used to identify various influences on free tropospheric air samples at Mauna Loa Observatory in Hawaii during MLOPEX. The cluster analysis separated thirteen chemical and meteorological variables into three characteristic groups (1)clean air, (2)anthropogenically influenced air, (3)marine and volcanic influenced air. The cluster analysis results compared well with those of factor analysis. Six independent components were identified in factor analysis. We have related these components to (1)volcano influenced air, (2)stratosphere-like air, (3)boundary-layer air with recent anthropogenic influence, (4)photochemical haze, (5)marine boundary- layer air, and (6)modified marine tropospheric air. Excluding local influence, we could calculate the nighttime free tropospheric values for $O_3$(41$\pm$10 ppbv), HN $O_3$(94$\pm$45 pptv), N $O_3$$^{[-10]}$ (16$\pm$10 ppbv), S $O_4$$^{[-10]}$ (60$\pm$0 pptv), N $H_4$$^{+}$(71$\pm$6 pptv), N $a^{+}$(5$\pm$1 pptv), PAN(13$\pm$9 pptv), MeN $O_3$(3.5$\pm$1.5 pptv), 2-butyl N $O_3$(0.6$\pm$0.1 pptv), $H_2O$$_2$(1015$\pm$44 pptv), $C_2$C $l_4$(3.3$\pm$0.1 pptv), condensation nuclei(249$\pm$13c $m^{-3}$), and dew point(-8.5$\pm$5.3$^{\circ}C$) during this experiment..

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The Protective Effect of Inhaled Heparin, Cromolyn, Budesonide, and Furosemide on Exercise-induced Asthma (운동유발성 천식의 기관지 수축에 대한 Heparin, Cromolyn, Budesonide, Furosemide 흡입 치료의 효과)

  • Lee, Sin-Hyung;Shim, Jae-Jeong;Lee, Sang-Youb;Cho, Jae-Youn;In, Kwang-Ho;Yoo, Se-Hwa;Kang, Kyung-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.6
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    • pp.1188-1198
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    • 1998
  • Background : The purpose of the present study was to determine the protective effect of antiasthmatic activity of inhaled heparin, cromolyn sodium, budesonide, furosemide in exercise-induced asthma(EIA). The other important considerable point of this study was the mechanism of bronchoconstriction on EIA. Methods : Eight subjects with a history of EIA were studied on 5 different experiment days. After obtaining baseline $FEV_1$ and FVC, subjects performed a standardized exercise challenge. EIA was assessed by measurement of $FEV_1$ before and after exercise. On experiment day 4, the exercise challenge was performed after the subjects inhaled either heparin (1,000 units/kg/day for 5 days), furosemide (1mg/kg for 5 days), cromolyn (4mg/day for 5 days), or budesonide ($400{\mu}g/day$ for 5 days). On experiment day 5, the methacholine bronchial provocation test was performed. On experiment day 3, activated partial thromboplastine time(aPTI) was checked. Results : Maximum decrements of $FEV_1$ (mean${\pm}$SE) among 0 to 120 minutes after exercise were as follows : heparin was $83.1{\pm}4.81%$ (p=0.010), furosemide was $80.5{\pm}6.87%$ (p=0.071), cromolyn was $86.8{\pm}6.53%$ (p=0.340), and budesonide was $79.4{\pm}7.31%$ (p=0.095). Above medications were compared to the control value ($72.5{\pm}18.2%$) by paired t-test. No medications had effect on $PD_{20}$ of methacholine bronchial provocation test The results were control $1.58{\pm}0.49{\mu}mol$), heparin ($4.17{\pm}1.96{\mu}mol$), furosemide ($1.85{\pm}0.86{\mu}mol$), cromolyn ($2.19{\pm}0.89{\mu}mol$), and budesonide ($3.38{\pm}1.77{\mu}mol$), respectively(p>0.05). The inhaled heparin had no effect of anticoagulation. Conclusion : These data demonstrate that inhaled heparin has a protective effect on EIA. The effect of inhaled cromolyn was statistically absent with manufacture's recommended dosage on EIA. So, the dosage of cromolyn should be carefully evaluated in future. Although inhalation of budesonide and furosemide have no statistical significance compared to control, these drugs also have some protective effects on EIA.

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Mucociliary Clearance in the Children with Bronchial Asthma (기관지 천식 환아에서의 점액섬모 청소율(Mucociliary Clearance))

  • Lee, Myung-Hyun;Sun, Yong-Han;Nam, Seung-Gon;Koh, Young-Yull;Chung, June-Key
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.2
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    • pp.173-181
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    • 1996
  • Background : Several studies have suggested that impaired mucociliary clearance plays a role in the pathophysiology of bronchial asthma. Cough productive of mucoid sputum is common, and mucous plugs in the airways are frequently observed. These clinical features are in keeping with the histologic lesions of asthma, which involve primarily the epithelial and mucous-producing structures of the conducting airways. Some studies have shown that the mucociliary clearance is impaired in adult asthma, but it has not been studied in childhood asthma. The objectives of this study were to examine whether the mucociliary clearance is impaired in childhood asthma and to estimate the degree of impairment in comparison with that of immotile cilia syndrome. Method : Thirteen children with mild stable asthma and eight patients with immotile cilia syndrome completed this study. Ten healthy children were recruited as a normal control group. The whole-lung mucociliary clearance was measured by the radioaerosol technique. Aerosols, tin colloid particles tagged with the radionuclide technetium-99m($^{99m}Tc$), were generated by means of nebulizer, and inhaled via a mouthpiece. The retention of radioactivity was measured at 30, 60, 90 and 120 minutes by gamma camera, and mucociliary clearance was calculated as percent retention at each time. Results: 1) In each subject, the percent retention decreased variably with the lapse of time. 2) The percent retention of radionuclide decreased at each time in order of normal control, bronchial asthma and immotile cilia syndrome and the percent retention of immotile cilia syndrome was significantly higher than that of normal control at each time(p<0.05). 3) At two hours, the percent retention of bronchial asthma($65.0{\pm}1.8$(SE)%) was significantly higher than that of the normal control($54.4{\pm}3.5%$, p<0.05), and significantly lower than that of immotile cilia syndrome($73.3{\pm}1.4%$, p<0.01). 4) When the percent retention was analyzed according to $PC_{20}$ in the children with bronchial asthma, they had no relationship with each other. Conclusion: Mucociliary clearance in the children with bronchial asthma was significantly lower than normal control. This finding indicates that impaired mucociliary clearance operates in childhood asthma as well, and suggests that it may be one contributing factor in the pathogenesis of asthma. The degree of impairment, however, was not so severe as immotile cilia syndrome.

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Traces of Gwan-a in Yanggeun and Jipyeong in Literature - with the Focus on the History, Scale and Sites of Gwan-a - (문헌으로 찾은 양근·지평 관아의 흔적 - 관아의 연혁·규모·터[址]를 중심으로 -)

  • Yu, Dong-Ho
    • Korean Journal of Heritage: History & Science
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    • v.51 no.1
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    • pp.80-99
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    • 2018
  • In premodern society, the central spaces in local counties were known as Eupchi (邑治), in which Gwan-a (官衙). The Eupchi located in seaside counties were in Eupseong, whereas the Eupchi of inland counties only included a Gwan-a, and did not have a fortress. Yanggeun-gun (楊根郡) and Jipyeonghyeon (砥平縣), which currently form Yangpyeong-gun (楊平郡), were counties where only Gwan-a existed. At present, there are few traces of the Gwan-a in Yanggeun and Jipyeong. In addition, it is impossible to exactly verify the history, scale and location of these two Gwan-as. Therefore, this study attempts to make a rough estimation of the histories, scales and sites of these Gwan-a by analyzing the relevant literature and ancient maps that are scattered according to the principles of spatial organization of local Gwan-a. The Yanggeun and Jipyeong Gwan-a appear to have been built in the early Joseon period. There are three reasons for this assertion: First, in Yanggeun and Jipyeong, Suryeong (守令) were first officially appointed after the early Joseon period. Once Suryoeng were appointed to such counties, the Gwan-a in which they would serve could be established. Second, the Dongheon (東軒) in Yanggengun and the Gaeksa (客舍) in Jipyeonghyeon were rebuilt in 1703 (29th year of the reign of King Sukjong) and 1465 (11th year of the reign of King Sejo), respectively; thus; the Gwan-a must have existed since the early Joseon period.. Third, in Yanggeungun, the Hyanggyo (鄕校) had existed since the early Joseon period, as the Joseon government necessarily established the Hyanggyo in areas where Suryeong were established. The facilities of local Gwan-a in the Joseon period were largely divided into gonghae (公?), educational institutes, and alters. The gonghae was a facility in which the Suryeong and Gwanwon (官員) managed administrative, judicial and military affairs, and consisted of the A-sa (衙舍), Hyeongcheong (鄕廳), Jackcheong (作廳), Gaeksa (客舍), Gungwancheon (軍官廳), and so on. The education institute was called a Hyeonggyo, while alters included the Sajikdan (社稷壇), Seonghwansa (城隍祠) and Yeodan (?壇). Both the Yeongeun and Jipyeong Gwan-a also consisted of such facilities as A-sa, Hyangcheong, Jakcheong, Gaeksa, Gungwancheong, Hyeonggyo, Changgo, Sajikdan, Seonghwangsa, Yeodan, Saryeongcheong, Jiincheong and Gwannocheong. The present sites for both Gwan-as cannot be identified with any certitude. However, they can be roughly identified by connecting the related literatures, oral statements and relics with the principles of spatial organization of local Gwan-a in the Joseon period. ${\bullet}$ Address of the Yanggeun A-sa (Dongheon): the whole of # 15, Gwanmun 1-gil, Yangpyeong-eup (Yanggeun-ri 151) in front of Yanggeun Junior High School at present. ${\bullet}$ Address of Yanggeun Gaeksa: around the Yangpyeong police station at present. ${\bullet}$ Address of Jipyeong A-sa(Dongheon): the whole of Jipyeong-ri 248-250, Jipyeong-myeon at present. ${\bullet}$ Address of Jipyeong Gaeksa: the whole of Jipyeong-ri 238, Jipyeong-myeon at present.