• RED RIBBON
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• s.72
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• pp.9-11
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• 2006

후천성 면역 결핍 증후군(AIDS, Aquired Immune Deficiency Syndrome)과 사람 면역결핍 바이러스 (HIV, Human Immunodeficiency Virus)관련 질환은 1981년 처음 AIDS가 보고된 이래 전 세계적으로 인류의 건강을 위협하고 있는 공중보건학적 문제이다. 그동안 HIV/AIDS 관련 질환에 대한 치료들은 주로 감염 경로 차단 및 관련된 내과적 질환의 치료에 초점이 맞추어져 왔다. 그러나 AIDS 환자 본인뿐만 아니라 가족, 치료진들은 흔히 HIV 감염으로 인한 심리적인 어려움에서부터 HIV 전파 위험을 높이는 물질 오남용 문제, 우울증, 치매 같은 전형적인 정신과 질환 및 자살에 이르기 까지 다양한 종류의 정신건강 상의 문제들에 자주 직면한다. 이와 같은 신경정신과적 문제들은 치료 결과나 예후, 삶의 질 등에 영향을 미칠 수 있기 때문에 환자의 가족들은 AIDS로 인한 정신과적 질환이나 현상들에 대해 잘 이해하고 적절하게 대처할 필요가 있다.

• RED RIBBON
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• s.63
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• pp.26-27
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• 2005

성교육의 단점은 일정한 형식이 없어서 너무 힘이 들지만 또 반대로 생각하면 그것 때문에 여러 가지를 고민하며 창조적인 수업을 만들어 갈 수 있는 장점도 있다. 물론 고민도 있다. 학생들 자신이 진짜 고민하는 이야기는 하나도 안 나오고 선생님이 준비해서간 자료들만 나열하는 수업에서 어떤 변화가 일어날 것인지? 그냥 수업시수만 때우는 것은 아닌가 하는 고민이 늘 내 주변을 맴돌고 있었다. 학력신장에만 정신이 없는 학교 구조 속에서 성교육의 설자리는 어디며 가장 핵심 가치는 무엇이고 어디서부터 시작을 해야 하는지? 개인적으로 그 고민이 가족역동 치료 공부하면서 많이 해소되고 길이 보이는 것 같다.

• RED RIBBON
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• s.83
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• pp.24-25
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• 2009

RNA 정량검사는 혈중 바이러스 농도를 측정하는 검사로, 감염인의 투약과 치료에 필수적인 검사로써 감염인이라면 $3{\sim}6$개월 간격으로 정기적으로 받는 검사이다. 그동안 국가에서 시행해 왔던 RNA 정량검사가 2009년 7월 1일자로 민간 의료기관에서 시행된다. RNA 정량검사를 민간 의료기관에서 실시하게 됨에 따라 감염인의 진료비 부담이 증가하게 된다. 병원에 따라서는 감염인의 비급여 본인부담금을 고려하여 특진료를 가산하지 않는 병원도 있으나 이는 극히 일부 병원에 불과한 실정이다.

• RED RIBBON
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• s.61
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• pp.10-11
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• 2004

전세계적으로 2003년 말 HIV감염자는 3,780만 명에 달하며 그중 여성이 차지하는 비율은$45\%$로 1,700만 정도 되며 15세 미만의 감염자가 210만 명을 차지한다. 우리나라의 경우 2004년 6월까지 총 2,842명의 감염자가 있으며 그중 여성 감염자는 288명으로 $10\%$를 차지,$70\%$이상이 20세에서 39세 사이의 가임기 연령이다. 이성간의 성접촉이 주된 감염경로인 아프리카와 아시아 일부 국가를 보면 남녀의 성비가 1:1에 가까운 데 비하여 우리나라 감염자의 성별 분포는 그렇지 않은 게 특징이다. 하지만 감염경로를 고려해 본다면 우리나라에서도 여성 감염자가 앞으로 더욱 증가할 수 있으며, 이는 향후 수직감염에 의한 신생아 감염도 늘 수 있어 무엇보다도 이에 따른 올바른 교육과 적절한 치료가 중요하다고 할 수 있겠다.

• Journal of Hospice and Palliative Care
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• v.4 no.1
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• pp.4-13
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• 2001

Purpose : Since the acquired immune deficiency syndrome (AIDS) was first recognized in the United States in the summer of 1981, the number of these patients has been increasing in the world. But do not find out a cure and a vaccine for ARS (5). And so, the best treatment for AIDS is the prevention. People can find out accurate knowledge about AIDS, and they can prevent themselves from AIDS approximately 100%. In this study, we investigate with AIDS knowledge and attitudes in unmarried young men (<24 age) and suggest accurate preventive education for AIDS and good sexual behaviors. Methods : Un-married young soldiers and college students who were not diagnosed as AIDS until June 30, 2000 were included in the study. The study included a total of 923 men. A self evaluation questionnaire, included questions on 36 items(the part of demographic data - 9; the part of knowledge - 20; the part of attitudes - 8), was drawn up by three physicians. The demographic data, AIDS knowledge and attitudes were analyzed by chi-square analysis, and the total score of AIDS knowledge - comparison according to demographic factors and attitudewere analyzed by one-way ANOVA test. Results : In demographic characteristics, as for the first recognized time of AIDS, most of men knew it when they were in their middle school, as for sources of information on AIDS, most of them knew it through the TV-media, and as for the educational need about AIDS, most of them agreed with it. In AIDS knowledge, mean scores were $14.0{\pm}1.8$ (70.3%). Items of the misconceptions concerning AIDS, reported as less than 50% correct answers, were 6 among 20 items (30%). In AIDS attitudes, as for the item about that if I will be an AIDS patient, I will have an AIDS treatment, it showed that the number of men agreed with 759 (82.2%), and as for the item about that I will help for AIDS patient even though I don't know him, it showed that the number of them agreed with 412 (45.8%). In correlation of AIDS knowledge and demographic factors, the mean scores of knowledge of men with higher than college degree were higher than them of others. The mean scores of knowledge of men with total income of family with more than US$1667 were higher than them of others. The mean scores of knowledge of men with sources of information on AIDS through the TV-media were higher than them of others. And the mean scores of knowledge of men with past medical history of STD(sexually transmitted disease) were higher than them of others. Conclusions : The higher the knowledge he has, the lower the possibility of risk and the more positive the attitude he has. And then we think that the education program for AIDS will be included as a regular part of the curriculum in high school, and young men must be effectively educated by it.

• Archives of design research
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• v.17 no.2
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• pp.373-382
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• 2004

The value of Korean ginseng has been known in the world since the 4th century B. C. Red ginseng is hot-steamed, and then dried for the purpose of long-term storing. Through the steaming and drying process, its moisture rate is reduced to 14% and its color becomes citrine or light yellowish brown. Its hardened structure enables long-term storage without any deformation. Especially, Korean red ginseng contains substances that promote micro-physiological activities which are not found in American or Sanchi ginseng. Ginseng is produced in diverse forms for the customer's convenience. In this study, these are classified as sliced, dried, and honeyed ginseng, granulated tea, extract, powder, capsules, tablets, drinks and candy. Package design is one of the most effective method in the marketing fields. However, in this research, we found that red ginseng packages are not variously and properly developed in materials and designs. The research pointed out the problems and discuss ways and means of the package design.

• Journal of Hospice and Palliative Care
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• v.17 no.3
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• pp.142-150
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• 2014

Purpose: This study was to identify the attitude of Korean HIV (Human Immunodeficiency Virus)-positive men toward death. Methods: A Q-methodology was performed with 20 HIV-positive male individuals. Participants were asked to select and answer questions among a set of 40 Q-statements using a 9-point scale. The collected data were analyzed using the PC QUANL program. Results: Participants' attitudes toward death were categorized into four types. Type I was characterized by respect for life, type II by reality orientation, type III by pain evasion and type IV religious beliefs. Conclusion: It is necessary to develop an assessment tool and an intervention program for HIV-positive individuals.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.57-57
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• 2001

Erythropoietin(EPO)는 혈액의 구성성분 중에서 적혈구 세포 증식에 중요한 기능을 한다고 알려져 있으며, 최근에는 암, 에이즈의 치료 등에도 효과가 있는 것으로 확인되고 있다. 따라서 본 연구팀은 지금까지 hEPO 유전자를 이용하여, 형질전환 돼지 "새롬이"의 생산에 성공한바 있다. 새롬이의 정액을 활용하여 인공수정을 실시 새롬이의 Fl를 24두 생산하였다. 이에 대하여 "형질전환 돼지의 계대번식시 유전자 전이효율에 관한 연구"라는 제목으로 발표 할 예정이며, 형질전환에 사용된 promoter가 WAP이므로, Fl이 임신, 분만을 하여야만 유즙을 통하여 hEPO물질을 생산할 수 있다. 따라서, Fl(♂)$\times$Fl(♀)의 교배에 의하여 5두가 임신, 분만을 하였으며, 이들 중 1두는 분만 후 21일에 폐사하였으며, 나머지는 현재 정상적으로 사육되고 있다. 이들 5두에 대하여 분만 후 유즙을 채취하여 유즙속에 EPO의 발현여부를 검토하였다. EPO-ELISA kit(medac)를 사용하여 분석결과, 유즙을 8,000배로 희석을 하여야만 Standard curve(1.25~160 mIU/$m\ell$)안에서 EPO의 단백질 발현을 검출할 수 있었다. 5두의 각각 농도는 28, 58, 17, 37, 27 IU/${\mu}\ell$ 였다. 또한 cDNA EPO와 genome EPO를 CHO 동물세포에서 생산하여 10배로 농축한 결과 5.5와 11 IU/${\mu}\ell$의 농도로 유즙과 비교하면 약 20~30배의 낮은 발현양을 나타내었으며, 또한 이러한 결과는 소변에서의 결과(1.1 IU/$m\ell$)보다는 약 30,000배 이상 높은 발현량을 화인 할 수 있었다. 현재, 이들 유즙 물질을 활용 빈혈 질환실험동물을 이용하여 생리활성을 검정, 체내에서 metabolic clearance rate(MCR)를 검토 중에 있다. 또한 F2의 자돈생산은 모돈 5두에서 총 25두가 생산되었는데, 이중 20두 약 80%가 EPO 유전자의 전환율을 나타내었다. 이상을 종합하면, 1) 돼지이용 생리활성물질(EPO)을 유즙에서 대량으로 생산할 수 있는 system의 활용가능성을 국내에서 처음으로 확인하였으며, 2) EPO에 있어서는 국제적으로도 형질전환 가축생산은 최초로 성공하였으며, 현재로서는 생산되어진 물질의 정제수준에 따라 활용가치가 결정되어 질 것으로 사료된다. 생리활성 물질을 생산할 수 있는 형질전환 돼지 생산의 성공은, 앞으로 형질전환 가축생산 뿐 만 아니라, 장기이식 및 복제돼지 생산의 활용 면에서의 응용가능성이 기대된다.

• Journal of Hospice and Palliative Care
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• v.20 no.3
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• pp.159-166
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• 2017

According to the advance of antiretroviral regimen and the early treatment strategy, people living with human immunodeficiency virus (PLWH) are achieving the goal of virologic suppression and immune restoration. Most of them no more die of acquired immunodeficiency syndrome (AIDS) defining illnesses, and become older with chronic comorbidities such as cardiovascular, metabolic, hepatic, renal and neurological diseases. However some PLWH still visit hospitals as late presenters with very low CD4+ T cell counts, so that they suffer AIDS defining illnesses to die or experience severe neurological complications resulting in disabilities. Early palliative interventions are needed on the various symptoms of PLWH. Thus far chronic pains such as distal symmetric sensory polyneuropathies have been underevaluated. Active pain-relieving interventions are important to them. Recently we define end of life condition of human immunodeficiency virus (HIV) or eligibility to hospice care after adjusting current status of HIV treatment. Hospice teams should pay attention to the specific medical conditions, psychological needs, and social circumstances of PLWH. With just standard precautions as common infection control measures, general hospice cares can be provided to them like to other hospices subjects. For giving PLWH opportunities to have the end of life with value and dignity, hospice multidisciplinary team should intervene them early and aggressively. Now we need more clinical experiences and institutional improvements.

• Journal of Hospice and Palliative Care
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• v.4 no.2
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• pp.122-129
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• 2001

Purpose : After Acquired Immunodeficiency Syndrome (AIDS) is known to be a fatal disease, efforts and studies are made to determine the cause, treatment method and method of preventing infection. However, no treatment method is present and vaccine development has not been made. Therefore, the most effective treatment method is prevention, and almost 100% prevention is possible when correct preventive measures are taken. We suggest effective prevention education by comparing knowledge and attitude of those unmarried men who had sexual encounters with prostitutes (high risk group) and those with no sexual encounters with prostitutes (low risk group). Methods : From January 1, 2000 to June 30, 2000, a survey was done in 516 unmarried soldiers and college students. With the collected data, chi-square test was used to compare and analyze the demographic characteristic, knowledge on AIDS, and attitude on AIDS between the high risk group and low risk group. One-way ANOVA test was used to compare and analyze the scores on knowledge between these two groups. Results : Among 516 unmarried men, 256 men (49.6%) fell into the high risk group and 260 men (50.4%) into the low risk group. Both groups showed that they heard of AIDS during their middle school years. The main route of obtaining knowledge on AIDS was through TV programs with 124 men(48.4%) in the high risk group and 167 men (64.2%) in the low risk group (P=0.002). Among 20 items, the average score on knowledge was $13.9{\pm}1.9$ in the high risk group and $14.1{\pm}1.8$ in the low risk group with no statistical difference between these two groups (P=0.191). Two items showed statistical significance in the low risk group compared with the high risk group; these were the item of AIDS being transmitted through transfusion (P=0.014) and through mosquitoes (P=0.009). As for attitude, statistical significance was present in the item stating that AIDS patients should be isolated in the high risk group compared with the low risk group (P=0.029). Conclusions : The present study showed that both the high risk group and low risk group obtained knowledge on AIDS through TV. No statistical difference was present between the two groups other than the high risk group showed statistically high results in two items on knowledge and one item on attitude. Thus, these results showed that exposure to AIDS can be lowered with better knowledge and the attitude of those with a low risk of infection was more positive.