• Proceedings of the KSLP Conference
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• 1998.11a
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• pp.185-185
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• 1998

배경 : 양성성대질환에 대한 기저막영역과 성대고유층에 대한 연구를 통해서 양성성대질환의 조직병리학적 특성이 밝혀지고 있으며, 질환발생과 관련된 병인과 병태가 밝혀지고 있다. 목적 : 양성성대질환의 병리학적 특성에 맞게 후두미세수술시 성대 고유층 최상층을 최대한 보호하고 병변부위만을 제거할 수 있는 성대점막하주입술의 유용성을 알아보고자 하였다. (중략)

• Proceedings of the KSLP Conference
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• 1997.11a
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• pp.263-263
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• 1997

성대결절, 폴립, 부종 등은 성대의 남용이나 과용등의 성대손상이 그 공통된 주된 원인으로 거론되고 있다. 하지만 음성치료를 비롯한 보존적 치료에 대한 반응이 서로 상이하며, H＆E 염색을 이용한 병리조직학적인 감별이 곤란하여 진단에 혼돈이 있으며, 치료의 방침을 결정하거나 예후를 예측함에 있어서도 어려움이 있다. 양성성대질환은 기저막부 위와 세포외 간질에 주된 변화가 발생함이 알려져 있고, collagen type IV의 발현양상이 성대결절과 폴립에서 서로 다름에 대하여는 보고된 바 있으나 기타 점막하층의 골격유지를 주기능으로 하는 대표적 세포외간질인 collagen subtype에 대하여는 아직 보고된 바가 없는 실정이다. Collagen 발현의 차이를 연구하는 것은 상기질환의 병인을 이해하고 질환분류의 guideline을 제시하며 나아가 적절한 치료방범을 제시하는 데에 큰 의미가 있을 것으로 기대된다. Paraffin에 고정되어 있는 5례 이상씩의 성대결절과 성대폴립, 육아 종 및 라인케씨 부종 조직을 collagen type I부터 VII에 대하여 peroxidase kit를 사용하여 염색한 후 각 군간에 collagen 분포양상과 발현정도에 차이가 있는가 비교하였다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1993.05a
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• pp.75-75
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• 1993

A retrospective review of 158 patients who had microlaryngeal surgery for benign vocal cord disease, at the Department of Otolaryngology, Kang-Nam St. Mary Hospital, over 2-year period from Mar. 1991 to Feb. 1993, was completed. Of 158 patients, 16 patients(10.1%, male 8 & female 8, most common in fifth decade) had concomitant vocal sulcus unilaterally (10) or bilaterally (6). Vocal sulcus was accompanied with 7.5% (7/93) of vocal polyp, 15.8% (6/38) of vocal nodule, 11.1% (1/9) of Reinke's edema and 8.3% (1/12) of vocal cyst. Vocal sulcus located above the associated disease in 13(59.1%), below the disease in 7(31.8%) and in the lesion in 2(9.0%). Vocal sulcus was found mainly on the midportion of the membranous vocal cord and the length was less than half of membranous vocal cord in 16(72.7%), more than half in 6(27.3%). In 12 cases (54.5%), vocal sulcus was deep enough to attach to the vocal ligament. We thought it is important to consider the concomitant vocal sulcus during the microlaryngeal surgery for benign vocal cord disease.

• Proceedings of the KSLP Conference
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• 1998.11a
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• pp.183-183
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• 1998

음성이 성대진동에 의해서 생성된다는 것이 밝혀진 이래로 이것을 확인해 보기 위한 많은 노력이 있어왔다. 특히 성대의 빠른 진동을 느린 움직임으로 정확하게 관찰하기 위해서 후두스트로보스코프같은 기구가 사용되고 있지만, 이것은 실제 시간에 따른 성대움직임을 보는 것이 아니고, 또 불규칙한 진동이 나타날 경우에는 성대점막의 움직임을 관찰하는 것이 불가능한 단점이 있었다. 저자들은 초 당 8000 개의 연속된 영상을 기록할 수 있는 videokymography를 이용하여 성대점막의 실제 시간에 따른 움직임을 관찰해보고, 후두질환에서 나타나는 영상을 확인해 보기 위하여 본 연구를 시작하였다. (중략)

• Proceedings of the KSLP Conference
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• 2003.11a
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• pp.143-143
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• 2003

음성에 대한 청각적 판단으로는 차이점과 공통점을 느낄 수 있으나, 개별적인 음향 분석에서는 차이점이나 공통점을 밝혀 내지 못한 경우가 많았다 따라서 음성에 대한 청각적 판단처럼 음향 분석 변수를 종합적으로 분석할 수 있는 MDVP와 Phonetogram을 이용하여 음성질환별로 나타나는 소견을 관찰하여 청각적 판단과 종합적인 음향학적 분석간에 연관성이 있는지 알아보고자 하였다. 음성변화를 주소로 본원에 내원하였던 환자 중 화상회선경술 검사상 양성성대질환이 관찰되었던 102명을 대상으로 하였고, 성대질환이 없었던 정상군과 비교하였다. 각 대상들은 화상회선경술 검사에서 질환의 종류를 확인하였고, 질환별 청각적 분석을 GRBAS로 확인하였다. 또한 MDVP를 시행하여 질환별로 변수들의 특징적인 변화를 종합적으로 도식화하여 확인하였고, Phonetogram을 시행하여 질환별로 감소된 부분이 있는지 확인하였다. (중략)

• Proceedings of the KSLP Conference
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• 2001.11a
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• pp.166-166
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• 2001

• Proceedings of the KSLP Conference
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• 2007.03a
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• pp.24-24
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• 2007

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.20 no.2
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• pp.131-135
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• 2009

Background and Objectives: Benign vocal fold lesions have shown various voice onset types on phonation, however, they have not been documented yet. We studied to know the relationships between benign vocal fold lesions and voice onset types. Materials and Method: 114 subjects were evaluated by using videokymographic examinations. The subjects were classified into three types: normal, contact, and open types according to the patterns of voice onset types on phonation. Benign vocal fold lesions were investigated and voice onset types were compared between normal and disease groups. Voice parameters were obtained from and compared in all subjects to assess acoustic and aerodynamic factors. Results: The normal type among onset types were more than contact type or open type in both normal and disease groups. Disease group showed many contact and open types when. compared with normal group. Vocal nodule and vocal polyp were showed many normal and contact types, however, sulcus vocalis was almost showed open type among voice onset groups. The values of mean flow rate (MFR) of contact type were significantly higher compared to normal type in disease group (p<0.05). Shimmer of contact type was higher than normal type in diseasegroup, but the difference was not significant (p=0.057). Conclusion: Benign vocal fold lesions were related to the various types of voice onset. The various types of voice onset should be considered when benign vocal fold lesions were examined.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.13 no.1
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• pp.40-44
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• 2002

Background and Objectives : Vocal abuse and misuse and muscle tension dysphonia that have various movements of false vocal folds may be related to the development of benign vocal folds lesions, such as vocal nodules, polyps, and cysts. This study was designed to determine whether benign vocal folds lesions were related with movements of false vocal folds on phonation. Material and Methods : One Hundred and seventy eight subjects were studied. All subjects received otolaryngological evaluation including videostroboscopy, objective voice measures. Patients were diagnosed as normal shape of vocal folds (group a), approximation of bilateral false vocal folds (group b), approximation of unilateral false vocal folds (group c), lateralized extension of false vocal folds (group d), and medialized approximation of posterior false vocal folds (group e). We analyzed the results of benign vocal folds lesions in each group. Results : Differences were found between the normal shaped group and the abnormal shaped group. No differences were found between each abnormal groups except group d and e. Conclusion : The shape of false vocal folds was related to the benign vocal folds lesions.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.14 no.1
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• pp.16-25
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• 2003

Background and Objectives : Electroglottography(EGG) is a non-invasive method of monitoring the vocal cord vibration by measuring the variation of physiological impedance across the vocal folds through the neck skin. It reveals especially the vocal fold contact area and is widely used for basic laryngeal researches, voice analysis and synthesis. The purpose of this study is to investigate the effectiveness of EGG parameters in differential diagnosis of laryngeal cancer. Materials and Methods : The author investigated 10 laryngeal cancer and 25 benign laryngeal disease patients who visited at the Department of Otolaryngology, Pusan National University Hospital. The EGG equipment was devised in the author's Department. Among various parameters of EGG, closed quotient(CQ), speed quotient(SQ), speed index(SI), Jitter, Shimmer, Fo were determined by an analysis program made with MATLAB 6.5$^{\circledR}$(Mathwork, Inc.). In order to differentiate various laryngeal diseases from pathologic voice signals, the author has used the electroglottographic parameters using the neural network of multilayer perceptron structure. Results : SQ, SI, Jitter and Shimmer values except those of CQ and Fo showed remarkable differences between benign and malignant laryngeal disease groups. From the artificial neural network, the percentage of differentiating the laryngeal cancer was over 80% in SQ, SI, Jitter, Shimmer except for CQ and Fo. These results indicated that it is possible to discriminate the benign and malignant laryngeal diseases by EGG parameters using the artificial neural network. Conclusion : If parameters of EGG which can reveal for the pathology of laryngeal diseases are additionally developed and the current classification algorithm is improved, the discrimination of laryngeal cancer will become much more accurate.