• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4326-4334
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• 2013

This study is descriptive research, attempts to determine the status of elderly inpatients of veterans hospital' of drug awareness information, drug use status and drug Misusage. The subjects were 220 patients of aged 65 and over only five metropolitan areas nationwide in drug use in the Veterans Hospital, national merit, the study is from May to June. SPSS Win 18.0 program was used as the data analysis and a statistical statement by mean, standard deviation, t-test and ANOVA, and multiple regression analysis. As a results, there was showed a statistically significant level 'age', 'type of marriage', 'education', 'triage', 'health status' as the general characteristics of the subjects. It showed the 'age' of the variables that influence recognition in the area of drug awareness information, and drug Misusage and drug use status factors seemed to affect the 'health status'. Therefore, It need for a comparative study of elderly inpatients and inpatients of veterans hospital, the research should be qualitative research of veterans medical services to the on reasonable support measures in the Veterans Affairs health care system and national merit.

• Journal of Home Health Care Nursing
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• v.24 no.1
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• pp.87-98
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• 2017

Purpose: The purpose of this study was to investigate the factors affecting medication errors and the medication management educational needs of community-dwelling older adults. Methods: From February 20 to February 23, 2017, 150 elderly people aged 65 or older were surveyed using a structured questionnaire. Results: A total of 85.7% of the older adults were taking medication, but their drug knowledge was found to be low. The medication error rate was 24.9%, and the score for medication management education requirement was 3.61 out of a possible 5points. Factors affecting medication errors were perceived health status and knowledge of medication, and their explanatory power was 43% in total. Conclusion: It was concluded that nursing intervention is needed to reduce older adults' medication errors and to increase their knowledge of medication. Additionally, groups of older adults with high medication errors should be intensively educated, and when developing a medication management education program, the contents of the sub-areas and items in which the participants' needs were high should be reinforced.

• Journal of Korean Academy of Nursing
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• v.46 no.5
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• pp.630-641
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• 2016

Purpose: This study was designed to construct a model which explains drug misuse behaviors in community-dwelling older adults. Methods: The design of this research is a cross-sectional study using structure equation modeling. The hypothetical model consisted of two types of variables: the exogenous variables of health status, cognitive ability, and negative emotion, and the endogenous variables of number of drugs, and drug misuse behaviors. The data collection was conducted from September 2 to September 21, 2013 through self-report questionnaires. Participants were 320 community-dwelling adults over the age of 65 living in J city. Data were analyzed with SPSS 21.0 program and Amos 18.0 program. Results: The results of the model fitness analysis were satisfied. The predictor variables for the hypothetical model explained 62.3% of variance regarding drug misuse behaviors. Drug misuse behaviors were directly affected by health status, cognitive ability, negative emotion and number of drugs and indirectly affected by health status, and negative emotion through number of drugs. Conclusion: These findings indicate factors that should be used in developing effective nursing interventions for safe and proper drug use and the prevention of drug misuse behaviors in community-dwelling older adults.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.11a
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• pp.1240-1243
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• 2023

의료기관에서 접근이 용이한 마약류 약물로 오남용하는 사례가 지속적으로 증가하고 있다. 이를 해결하고자 본 논문은 블록체인 프레임워크인 하이퍼레저 패브릭을 기반으로 구축된 약물 오남용 관리 시스템을 제안한다. 하이퍼레저 패브릭의 분산 원장 기능을 사용하면 의약품 거래를 투명하게 기록하고 처방 기록을 안전하게 보존하여 모든 거래 세부 정보를 변조할 수 없게 된다. 또한 약물 사용 기록을 추적하고 남용을 방지하기 위해 과다 복용 사용자를 규제하는 기능을 제안한다. 본 논문이 약물 오용을 크게 완화하고 과다 복용 사용자 보호가 가능할 것이라 기대한다.

• The Journal of the Korea Contents Association
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• v.16 no.9
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• pp.791-805
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• 2016

The purpose of this study was to understand the essential meanings in experiences of medication misuse and abuse behavior in elderly people with chronic disease in community. The participants were 10 patients with chronic disease over 65 ages who were selected by convenience sampling. Data were collected through individual in-depth interviews from February to May 2014, and were analyzed using Colaizzi (1978)'s phenomenological analysis method. As a results, the essential meanings and structure of medication misuse and abuse behavior experience in elderly people with chronic disease were derived into five clusters of themes as follows: 'Burden on the medications', 'Anxiety about the side effect of the medications or the disease exacerbation', 'There is no alternative other than the medications', 'Expectations of the medications effect for my criteria', 'Lack of understanding on the correct medication use'. The results of this study contributed to promoting a deeper understanding of medication misuse and abuse behaviors in elderly people with chronic disease, and provided for the basic data of strategic development for the prevention of medication misuse and abuse behaviors from the perspective of elderly people with chronic disease in community.

• Korean Journal of Adult Nursing
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• v.23 no.6
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• pp.554-563
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• 2011

Purpose: The purpose of this study was to investigate factors associated with drug misuse behaviors among polypharmacy elderly. Methods: This was a cross-sectional survey. Participants consisted of 116 polypharmacy elderly who were taking 5 or more medications each day. Data were collected via face to face interviews. Data were analyzed using the PASW 18.0 program. Data concerning predisposing factor (knowledge, benefit), enabling factor (communication with health care provider), and need factor (perceived health status, number of disease) were collected. Results: The total mean score of drug misuse behaviors among polypharmacy elderly was 3.04 out of 10 points. Communication with health care provider, perceived health status, and knowledge were found to be significantly correlated with drug misuse behaviors. In stepwise multiple regression analysis, a total of 42% of the variance in drug misuse behaviors was accounted for communication with health care provider, perceived health status, and knowledge. Conclusion: Therefore, education program for improving communication with health care provider, and knowledge should be designed and provided for polypharmacy elderly.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.15 no.2
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• pp.195-205
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• 2008

Purpose: This study was conducted to identify drug use by elders. Method: There were 304 participants age 65 or older included in this study. Data were collected using a questionnaire about drug use in the past 4 weeks. The questionnaire, a modification of Uhm's (2005), Lee's (2001), and Ellor and Kurz's (1982) tools, consisted of 17 questions on general and health characteristics, 17 on drug usage and 9 on behaviors related to drug misuse. Results: 85.5% of participants reported laking at least one type of prescription or non-prescription drug. 26.0% of participants reported taking only prescription drugs, 3.9% reported taking only non-prescription drugs, and 55.6% reported taking both prescription and non-prescription drugs. 17.1% of participants reported side effects from the drugs. The mean score for behaviors related to drug misuse was 7.53. Elders taking only non-prescription drugs showed more drug misuse than elders taking only prescription drugs or both. Women used more prescription, non-prescription drugs or both than man. Elders in rural areas used more non-prescription drugs than those in urban areas. Conclusion: Even though pharmacies were separated from medical practices in 2000, most older adults continue to use and misuse prescription and non-prescription drugs.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.125-125
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• 1995

Quinolone계 항균제인 rufloxacin의 전임상시험의 일환으로 항원성 유발여부를 평가하기 여부를 평가하기 위하여 아나필락시스 쇼크 반응시험, 수동 피부 아나필락시스 반응시험 및 간접 적혈구 응집 반응시험을 실시하여 다음과 같은 결과를 얻었다. 1. 기니픽을 이용한 아나필락시스 쇼크 반응시험에서 rufloxacin의 저용량투여군(1mg/body, 추정임상용량), 고용량투여군(5mg/body), 고용량혼합투여군(5mg/body mixed with Freunds' complete or incomplete adjuvant) 및 단백결합혼합투여군(rufloxacin-BSA, 1mg/body)에 있어서 아나필락시스 쇼크 반응이 관찰되지 않았다. 2. 마우스-랫드를 이용한 수동 피부 아나필락시스 반응시험에서 저용량투여군, 고용량투여군, 오용량혼합투여군 및 bovine serum albumin(BSA)과 결합시킨 단백결합혼합투여군 모두에서 음성의 반응을 나타내었다. 3. 간접 적혈구 응집 반응시험 결과 저용량투여군, 고용량투여군, 고용량혼합투여군 및 단백결합혼합투여군에서는 각군당 1-4마리에서 16-32배에서 양성반응을 나타내었다. 그러나 음성대조군에서도 10마리 중 4마리에서 16-32배에서 양성반응을 나타낸 것으로 미루어 약물투여군에서의 미약란 양성반응이 약물특이적 반응은 아닌 것으로 사료된다. 이상의 실험결과로 미루어 rufloxacin은 항체 생성능은 가지지 않는 것으로 사료된다. 이상의 실험결과를 종합하여 볼 때 ndloxacin은 전반적인 항원성 potential은 없는 것으로 사료되며 또한 생체내에서 체내 단백과 결합하여 hapten으로 작용할 가능성은 없는 것으로 사료된다.

• Communications for Statistical Applications and Methods
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• v.16 no.4
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• pp.595-603
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• 2009

Typically the standard optimal allocation method distributes the sample for each stratum considering survey cost. In case of varying survey cost for each survey unit, we need to consider more practical allocation method. In other words, according to characteristics of an individual unit, we consider the optimal dynamic allocation method which first selects the survey unit having maximum value of benefit cost ratio. In terms of this, the proposed allocation method is different from standard optimal allocation method which allocate samples for each stratum and selects the random sample according to each size of sample. This paper is considered the dynamic optimal allocation method for the stratified randomized response technique which surveys for sensitive characteristic of survey units such as drug abuse, abortion, alcoholic. We prove the practical usefulness of proposed method using the numerical example.

• Korean Journal of Adult Nursing
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• v.27 no.6
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• pp.665-672
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• 2015

Purpose: The aims of current study were to assess the inhaler competency and medication adherence, and to identify association of inhaler competency with medication adherence in patients with obstructive lung disease. Methods: We did a secondary analysis of the Hanyang Obstructive Pulmonary Evaluation data in a single institution from June 2014 to April 2015 after an approval of Institutional Review Board. A total of 150 patients with asthma or chronic obstructive lung disease participated in the study. Inhaler competency was evaluated accuracy in each step for using metered dose inhaler. Medication adherence was calculated using actually dispensed doses based on the prescribed inhaler doses. Results: Older adults (${\geq}65$) had lower competency in using inhaler (66.7 vs 83.3, z=-4.52, p<.001) and poorer medication adherence (67.7 vs 91.8, $x^2=14.06$, p<.001) than adults (<65). Inhaler competency was associated with medication adherence (p=.26, p=.001). Surprisingly, more than 50% of patients were current smokers. Conclusion: Inhaler competency and medication adherence were lower in older adults with obstructive lung disease than those in adult-age patients. Therefore, an individual education program for older patients should be developed to improve the rates of proper use of inhalers. Nursing management for obstructive lung disease should focus on developing behavioral intervention strategies for smoking cessation.