• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.134-141
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• 1999

Objects : Cancer patients receiving radiotherapy have many psychological problems. Those problems depend on clinical factors of cancer and the characteristics of patients. This study was designed to estimate the morbidity of psychiatric disorder and to investigate the relationship between psychiatric disorders and clinical variables. Methods : The subjects were 47 patients who had been treated by radiotherapy. Psychiatric disorder was diagnosed according to DSM-IV. The authors assessed the relation between psychiatric disorder and demographic features, clinical features of cancer such as site, duration, frequency of recurrence of cancer, and patients' awareness of disease and expectation of outcome of radiotherapy. Results : 21 patients(44.7%) had a psychiatric disorder. The most common psychiatric disorder were adjustment disorder(66.7%), and the next major depressive disorder(23.8%). There was a significant positive relationship between psychiatric disorder and recurrence of cancer, patients' expectation of poor outcome after radiotherapy. Psychiatric morbidity was significantly low in those who had no evidence of recurrence and who considered radiation treatment as curative. However, site and duration of cancer, patients' awareness about serious illness were not related with psychiatric disorder. Conclusion : Psychiatric disorders are common among cancer patients on radiotherapy. Further clinical attention and effective treatment of psychiatric complication in cancer patients are needed not only for reducing symptoms but for better adjustment.

• Journal of the Korea Convergence Society
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• v.9 no.12
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• pp.467-474
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• 2018

This is a qualitative research that was carried out to analyze the childhood cancer survivors' perceived difficulties using the result of focus group interviews. This study conducted interviews with 22 childhood cancer survivors under follow-up management after cancer treatment at general hospitals in Korea. 22 persons were divided into 3 groups, and interviews were carried out with each group for 80-100 minutes. As a result of the research, four topic collections consisting of 'Physical limitation', 'Influence of lasting childhood cancer', 'Difficulty in forming relationships' and 'Lack of reliable information' and seven subjects, which consist of 'Lack of energy', 'Potential late-effects', 'Fears about cancer recurrence', 'Negative social awareness', 'Difficulty in interacting with', 'Difficulty in interacting with peers', and 'Difficulty in interacting with families' were derived. Based on the findings of this research, it is hoped that provides a basis for developing appropriate and effective services and programs for childhood cancer survivors.

• Journal of East-West Nursing Research
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• v.11 no.2
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• pp.146-154
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• 2005

Purpose: This study was designed to identify the relationship between quality of life, perceived health status, perceived susceptibility severity to recurrence of cancer and character of object in cancer patients to provide the basic data of effective nursing interventions. Method: The subject of this study was randomly chosen from the patients diagnosed of cancer and being hospitalised or receiving chemotherapy as outpatients, at a Division of Hemato-Oncology, Department of Internal Medicine of a university hospital located in Seoul. The tool used in this study was a measurement tool for quality of life (${\alpha}=.829$), perceived health status (${\alpha}=.903$), and perceived susceptibility and severity for cancer recurrence (${\alpha}=.860$). The collected data were analysed using SPSS PC 12.0 Programme for real number, percentage, average, standard deviation, Pearson's Correlation, t-test and ANOVA, according to the purpose of this study. Result: 1) The score of quality of life in cancer patients was 3.64 point, perceived health status was 2.62 and perceived susceptibility severity to recurrence of cancer was 2.41. 2) There was a significant difference in the quality of life according to general characteristics, such as level of education, occupation, level of activity, pain, medication period, diagnosis, disease stage, purpose of medication, and recurrence. There was a significant difference in perceived health status according to age, level of activity, pain, diagnosis, purpose of medication, and recurrence. There was a significant difference in perceived susceptibility severity to recurrence of cancer according to age, level of education, and pain. 3) The cancer patients' quality of life showed significant correlation with perceived health status, perceived susceptibility severity to recurrence of cancer, pain, job, treatment purpose, relapse. The perceived health status showed significant correlation with perceived susceptibility severity to recurrence of cancer, pain, treatment purpose, relapse. The perceived susceptibility severity to recurrence of cancer showed significant correlation with pain. The relapse showed significant correlation with treatment purpose. The cancer patients' quality of life, perceived health status, and perceived susceptibility and severity for cancer recurrence, as confirmed above, showed differences according to the related factors of each subject, and it was also confirmed that those factors were significantly related with general characteristics. Upon these results, I suggest further studies on the factors that affect the cancer patients' quality of life.

• Radiation Oncology Journal
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• v.21 no.2
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• pp.112-117
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• 2003

Purpose: The effects of hypefractionation radiation therapy, such as the failure pattern and survival, on the treatment results in advanced stage head and neck cancer were studied. Materials and Methods: Between September 1990 and October 1998, 24 patients with advanced stage (III, IV) head and neck cancers, were treated using hyperfractionation radiation therapy in the Department of Radiation Oncology at the Keimyung University Dongsan Medical Center. The male to female ratio was 7 : 1, and the age range from 38 to 71 years with the median of 56 years. With regard to the TNM stage, 11 patients were stage III and 13 were stage IV. The sites of primary cancer were the nasopharynx in six, the hypopharynx in 6, the larynx in five, the oropharynx in three, the maxillary sinus in three, and the oral cavity in one patient. The radiotherapy was delivered by 6 MV X-ray, with a fraction size of 1.2 Gy at two fractions a day, with at least 6 hours inter-fractional interval. The mean total radiation doses was 72 Gy, (ranging from 64.4 to 75.8 Gy). Follow-up periods ranged between 3 and 136 months, with the median of 52 months. Results: The overall survival rates at 3 and 5 years in all patients were 66.7$\%$, and 52.4$\%$. The disease-free survival rates at 3 and S years (3YDFS, 5YDFS) in all patients were 66.7$\%$ and 47.6$\%$. The 3YDFS and 5YDFS in stage III patients were 81.8$\%$ and 63.6$\%$, and those in stage IV patients were 53.8$\%$ and 32.3$\%$. Ten patients were alive with no local nor distant failures at the time of analyses. Six patients (25$\%$) died due to distant metastasis and 12.5$\%$ died due to local failure. Distant metastasis was the major cause of failure, but 2 patients died due to unknown failures and 3 of other diseases. The distant metastasis sites were the lung (3 patients), the bone (1 patient), and the liver (2 patients). One patient died of second esophageal cancer. There were no severe late complications, with the exception of 1 osteo-radionecrosis of the mandible 58 months after treatment. Conclusion: Although this study was peformed on small patients group, we considered hypefractionated radiation therapy for the treatment of advanced stage head and neck cancer might improve the disease free survival and decrease the local failure with no increase in late complications despite of the slight Increase in acute complications.

• Proceedings of the KAIS Fall Conference
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• 2010.05b
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• pp.1077-1082
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• 2010

본 연구는 일반 여성과 유방암 환자를 대상으로 유방 자가검진의 이행율과 유방 자가검진에 영향을 미치는 요인을 파악하기 위하여 시도된 단면적 조사 연구이다. 건강신념 변수에 대해 일반 여성군과 유방암 환자군을 비교하면 일반 여성군이 유방암 환자군에 비해 유방암에 대한 심각성이 높은 것으로 나타났다. 유방암 환자군에서는 일반 여성군에 비해 유방암에 대한 민감성이 높았으며, 유방암 검진에 대한 유익성이 높고, 건강관심도가 높은 것으로 나타났다(p<0.01). 건강신념 변수에 대해 유방 자가검진 이행자와 불이행자를 비교해 보면 유방 자가검진 이행자는 불이행자보다 건강 관심도가 높고(p<0.01) 유방 자가검진에 대해 설명을 들은 경험이 있는 경우 자가검진 이행율이 높은 것으로 나타났다(p<0.05). 유방 자가검진 불이행자에서는 이행자보다 건강관심도가 낮고, 주위에서 유방 자가검진을 권하는 사람이 없는 경우가 많았다(p<0.01).유방 자가검진 이행자와 불이행자간 민감성, 심각성, 유익성, 장애성에 대해서는 유의한 차이가 없는 것으로 나타났다. 유방 자가검진 이행 여부에 관해서는 유방암 환자군이 일반 여성군에 비해 유방 자가검진을 3.5배 시행하지 않는 것으로 나타났고(p<0.01), 연령은 40대 미만보다 60대 이상여성이 1.6배 유방 자가검진을 시행하지 않는 것으로 나타났다. 교육수준은 대졸이상 보다 고졸이하가 2.4배 유방 자가검진을 시행하지 않고, 가구 소득은 200만원미만보다 400만원이상 고소득자가 2.7배 유방 자가검진을 시행하지 않는 것으로 나타났다. 자녀수는 자녀가 없는 여성이 자녀수가 3명이상인 여성에 비해 12.1배 유방 자가검진을 시행하지 않는 것으로 나타났다(p<0.05). 건강 신념과 유방 자가검진 실천의 관계를 본 결과 건강관심도와 행동계기가 유방 자가검진 수행에 유의한 영향을 미치는 것으로 나타났다. 건강관심도가 높을수록 유방 자가검진 실천도가 높고, 행동 계기 즉 주위에서 유방 자가검진을 권하는 사람이 있는 경우가 유방자가검진 수행율이 높은 것으로 나타났다(p<0.05). 본 연구 결과를 통해 유방암 환자를 포함한 일반여성을 대상으로 유방 자가검진의 중요성과 유방 자가검진 방법에 대해 정기적인 교육 프로그램, 포스터, 안내책자 등을 통한 적극적인 교육과 권유가 필요할 것으로 보여 진다. 유방 자가검진 프로그램 개발 시 유방암 환자와 일반 여성을 대상으로 한 차별화 된 교육 프로그램 개발이 필요하고 이를 통해 유방암 환자에게 유방암의 재발 위험성과 자가검진의 필요성, 올바른 유방암 환자의 자가검진법을 인지시킴으로서 유방 자가검진 실천율을 향상 시킬 수 있을 것이라고 생각된다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.6.1-6
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• 1982

Papilloma is the common benign tumor of the larynx and the incidence of its malignant change was variable. The authors recently experienced 2 cases of squamous cell carcinoma of the larynx which were considered to be transformed from laryngeal papilloma. Case 1. A 58 year old male patient visited O.P.D. of Department of Otolaryngology of Busan National University Hospital, because of hoarseness for 3 years on May 13th, 1980. At that time, local finding of indirect laryngoscopy revealed whitish hypertrophic papillomatous mass on both vocal cords and anterior commissure, and dirty gray white pseudomembrane on left aryepiglottic fold, and the result of biopsy was squamous cell papilloma. So the laryngeal papilloma was removed under suspension laryngoscopy and then he had no specific treatment in spite of being recommended 5-FU topical spray. On March 5th, 1981, he visited O.P.D. again because of progressive exacerbation of hoarseness with mild dyspnea and histopathological finding was revealed squamous cell carcinoma of the larynx. Seven days later from that day, he visited emergency room due to severe dyspnea, and emergency tracheostomy was performed on sitting position. On April 7th 1981, total laryngectomy was performed successfully and postoperative irradiation therapy was recommended. Case 2. A 47 year old male patient visited our O.P.D. because of hoarseness for 5 years on Sep. 27, 1978. At that time, local finding of indirect laryngoscopy revealed papillomatous mass on left vocal cord and left ventricle and result of biopsy was squamous cell papilloma. So he had been treated with 11 times removal of papilloma, topical spray of 5-Fu and estrogen for 3 years, but the papilloma had been recurred. On Sep. 9th, 1981, he visited O.P.D. because of severe dyspnea and emergency tracheostomy and biopsy was performed. The result of biopsy was squamous cell carcinoma of larynx and total laryngectomy was performed successfully.