• Radiation Oncology Journal
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• v.27 no.3
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• pp.169-172
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• 2009

Intraocular metastasis is the most common malignancy of the eye. The frequency of intraocular metastasis in all the patients dying of cancer is about 12% and ocular metastases will be detected more frequently in the future because the patients with malignant tumor are now living longer. Intraocular metastasis can cause a serious clinical problem such as blindness. The early recognition and treatment of intraocular metastasis are very important clinical oncologic issues to maintain vision and to maximize the quality of life. However, significance of intraocular metastasis is still under-evaluated for practicing oncologists. External beam radiotherapy is a safe, effective palliative treatment in terms of preserving both the vision and the eye globe.

• The Korean Journal of Vision Science
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• v.20 no.4
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• pp.497-504
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• 2018

Purpose : The purpose of this study was to investigate the temperature changes of the ocular surface before and after cataract surgery using thermography of a thermal imaging camera. Methods : The study included 75 patients (75 eyes) aged from 50 to 79 years who underwent cataract surgery. In the past, those who underwent corneal-related surgery, wearing contact lens, disorder of tear secretion and taking medication for systemic disease were excluded from this study. The temperature changes of the eyeball surface were measured using a thermal imager (Cox CX series, Answer, Korea) following Tear Break Up Time (TBUT) test, Mcmonnies questionnaire and Schirmer's Test in real time, Results : While the temperature of preoperative ocular surface was $35.20{\pm}0.54^{\circ}C$ and that of postoperative temperature was $35.30{\pm}0.53^{\circ}C$, the difference was not significant. The temperature changes in the ocular surface were statistically significant at $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$) before the surgery and $-0.18{\pm}0.07{\Delta}$ ($^{\circ}C/sec$) after the surgery. In comparison of the age groups, it was shown that the changes in the surface temperature before the surgery were from $-0.19{\pm}0.05{\Delta}$ ($^{\circ}C/sec$) to $-0.14{\pm}0.09{\Delta}$ ($^{\circ}C/sec$) in the 50s group, and from $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$) to $-0.15{\pm}0.07{\Delta}$ ($^{\circ}C/sec$) in 60s group, and $-0.18{\pm}0.07{\Delta}$ ($^{\circ}C$) to $-0.12{\pm}0.08{\Delta}/sec$) in the 70s group, showing significant changes in the ocular surface temperature at all ages. Conclusion : Following the cataract surgery, all the indicators of dry eye syndrome were decreased, and eye surface temperature changes were significant. The thermography technique of the ocular surface would be expected to be useful for the evaluation of various dry eye syndromes because it is easy to evaluate dry eye syndrome noninvasively and can be quantified.

• Tuberculosis and Respiratory Diseases
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• v.50 no.5
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• pp.624-629
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• 2001

Metastatic tumors to the eyes are probably the most common type of intraocular malignancies. The most common metastatic tumor is the breast cancer overall and lung cancer in men. An eyeball metastasis from lung cancer has a poor prognosis. Differentiating an eyeball metastasis from the primary malignant melanoma is important. Eyeball metastasis of a lung adenocarcinoma confirmed by pathology has not reported in Korea. Here we report a case of a metastatic lung adenocarcinoma to the eyeball confirmed by enucleation and a transbronchial lung biopsy with a review of the relevant literature.

• Korean Journal of Psychosomatic Medicine
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• v.15 no.2
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• pp.73-80
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• 2007

Anumber of prior studies have reported eye movement dysfunction in patients with dementia. The eye movement test which is non-invasive can evaluate the local brain function quantitatively. Therefore, it can be a useful method for characterizing regional brain abnormalities of patients with dementia. The aim of this paper is to review the literatures on eye movement abnormalities in dementia patients. Saccade system dysfunctions in Alzheimer disease include increased latency, reduced accuracy, and increased antisaccade error rates. Patients with frontotemporal dementia showed impaired reflexive saccade inhibition and increased latency and errors of antisaccade task. And delayed initiation of voluntary saccades, slow saccades, and increased errors and latency on antisaccade task were found in Huntington's disease. Patients with Parkinson’s disease dementia and dementia with Lewy bodies have characteristics of impaired in both reflexive saccade execution and complex saccade performance. However, there were few reports of abnormal eye movements in Creutzfeldt-Jakob disease; they could be found at the later stages after symptoms of dementia came to be evident, and secondary to cerebellar and vestibular involvement. Slowing of saccades and hypometric saccades might precede the supranuclear limitation of vertical gaze in PSP. Dysfunction of voluntary eyelid movements was a characteristic finding of PSP as well. In conclusion, patients with dementia can show various abnormal eye movements and they are related with cortial and subcortical brain dysfunctions. The research on localization of brain relevant to each symptom can promise more clinical implications of eye movement of dementia.

• Journal of Korea Entertainment Industry Association
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• v.14 no.6
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• pp.191-199
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• 2020

Younger generations use a variety of visual media, such as smartphones, televisions, and computers. Due to the development of visual media, the health of eye was weakening. Therefore, this study aimed to investigate the effects of eye health and dynamic visual activity on eye muscle stimulation with eye movement and therapeutic massage in university students. 38 university students in their 20s were divided into a control group(18) and an experimental group(20). The experimental group performed eye movement and therapeutic massage every 30 minutes for 5 times a week for 4 weeks. Ocular fatigue, maximal blinking interval, ocular surface temperature, and dynamic visual activity were measured before and after 4 weeks. Ocular fatigue was decreased significantly after 4 weeks (p<.05), and maximal blinking interval was increased significantly after 4 weeks (p<.05). Ocular surface temperature was not showed a significant difference after 4 weeks (p>.05), and dynamic visual activity was increased significantly after 4 weeks (p<.05). Therefore, eye movement and therapeutic massage are recommended for the improvement of eye function and eye health. It is expected to be used as research data to restore and prevent for eye health.

• Proceedings of the KAIS Fall Conference
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• 2010.05b
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• pp.890-893
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• 2010

알코올 섭취 후 발생하는 해부생리학적 변화가 눈의 일시적인 근시화에 미치는 영향을 알아보고자 하였다. 평균 24.5${\pm}$1.5세의 남자 8명(16 안)을 대상으로 0.42 g/kg의 알코올을 30분 간에 걸쳐 섭취토록 한 다음, 알코올 섭취 1시간, 4시간, 24시간 후의 교정굴절력, 각막곡률반경과 두께, 동공직경, 안압, 그리고 안구축의 길이변화를 측정하여 알코올 섭취 전과 비교하였다. 알코올 섭취 1시간 후에 알코올 섭취 전과 비교하여 호흡 중 알코올 농도가 가장 높았고(p<0.001), 교정굴절력의 구면 (-)굴절력 증가(p<0.05), 동공 크기의 감소(p<0.05), 안압의 하강(p<0.001), 그리고 안구축의 길이 증가가 나타났다. 알코올 섭취 4시간 후에도 모든 측정값들이 섭취 1시간 후와 동일한 경향이었다. 그러나 알코올 섭취 24시간 후에는 알코올 섭취 전과 비교하여 의의있는 변화를 보이지 않았다. 알코올 섭취로 인한 일시적인 근시화는 안압하강과 안구축의 길이변화와 관련성이 있을 것으로 판단된다.

• Clinical and Experimental Pediatrics
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• v.51 no.1
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• pp.84-88
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• 2008

Purpose : Radiotherapy is effective in local treatment for retinoblastoma. However, asymmetric facial hypoplasia after radiation is a serious late effect. This study was performed to investigate the effects of enucleation and chemotherapy with or without radiotherapy in advanced intraocular and intraorbital retinoblastoma. Methods : Between 1985 October and 2006 December, the records of thirty five patients who were diagnosed as retinoblastoma at Yeungnam University Hospital were reviewed. Advanced intraocular and intraorbital retinoblastoma patients classified as Reese-Ellsworth group III, IV, and V and Grabowski- Abramson class II were selected for the study. Results : Eighteen patients were enrolled in this study. All patients were enucleated and had received chemotherapy. Nine patients received radiotherapy and nine patients didn't receive radiotherapy. Tumor cells were found on resection margin of optic nerve in five of nine patients who received radiotherapy, but none of nine who didn't receive radiotherapy. Chemotherapy included vincristine, adriamycin, cyclophosphamide, VM-26, cisplatin before 2001, and vincristine, etoposide, and carboplatin after 2001. There were no recurrences or metastases in nine patients who didn't receive radiotherapy. But two of nine patients who received radiotherapy had metastases to brain. However, all survivors who received radiotherapy had significant facial asymmetry. Conclusion : In advanced intraocular and intraorbital retinoblastoma without tumor cell on resection margin of optic nerve, enucleation and chemotherapy without local radiotherapy appears to be safe for long-term survival. However, in those with tumor cells on resection margin of optic nerve, enucleation and chemotherapy with local radiotherapy seems to be necessary to improve survival.

• Journal of Veterinary Clinics
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• v.27 no.5
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• pp.610-613
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• 2010

An 8-year-old male dog weighing 7.9 kg was referred to us for evaluation of exophthalmos and corneal edema of the left eye, on which cataract surgery had been performed 3 years prior. On ophthalmic examination, the left eye showed an extremely high intraocular pressure (47 mmHg), with no menace response, dazzle reflex, or pupillary light reflex. The dog was treated with systemic and topical glaucoma medications. After treatment, corneal edema decreased but IOP did not return to within acceptable limits. Seventeen months later, the dog presented with hyphema, episcleral congestion, and corneal edema attributable to accidental trauma. The owner wished to maintain an attractive ocular appearance, and an intraocular silicone prosthesis (ISP) was thus inserted after the evisceration. Three months postoperatively, a corneal ulcer was detected, but this resolved successfully after prescription of appropriate medication. One year after surgery, no complications related to surgery were evident.

• 한국HCI학회:학술대회논문집
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• 2007.02b
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• pp.633-638
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• 2007

본 연구에서는 신체상 위협상황에서 대처 전략을 측정할 수 있는 한국판 신체상 대처전략 척도(K-BICSI: The Korean Version of the Body Image Coping Strategy: K-BICSI)를 사용하여 회피 전략을 사용하는 정도에 따라 고회피집단(N=12)과 저 회피집단(N=12)으로 구분하여 실험참가자를 모집하였다. 연구의 목적은 외모 관련 자극이 제시 되었을 때 달라지는 주의편향과 자극 제시 전후의 정서변화를 살펴보는 것이었다. 실험 참가자는 여대생 24명으로, 안구운동 추적장비의 최초 응시방향과 응시시간을 이용해 주의편향을 확인했으며, 정서변화는 VAS로 측정하였다. 분석 결과 고 회피집단은 저 회피집단에 비해 비매력자극에 대한 더 높은 최초응시 경향을 나타냈지만, 매력자극에 대해서는 유의미하게 긴 응시시간을 보였고, 외모관련 지극 제시 전보다 후에 더 유의미하게 정서가 부정적으로 변하였다. 본 연구의 결과로 고 회피집단은 저 회피집단과는 다른 주의 인지기제를 가지고 있으며 외모관련 자극에 정서적으로 민감하게 반응한다는 것을 확인할 수 있었다.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.2032-2037
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• 2010

충청남도 서해안은 생태환경의 보고로서 갯벌, 사구, 해안습지 등 독특한 자연적 특성을 갖고 있는 지역이다. 그러나 다른 지역에 비해 대규모 간척 및 매립으로 인한 해양생태계 피해에 현저히 노출되어 있으며, 서해안 지역은 최근 산업화 및 관광권화가 진행되며 무분별하게 설치된 호안구조물은 그 기능을 상실하여 상당수가 설치전보다 오히려 서해안의 독특한 환경성과 관광성을 악화시키고 있어 서해안 특성을 고려한 대책이 요구된다. 본 연구에서는 서해안의 특성을 고려한 환경친화적 연안 호안구조물 리모델링을 위해 서해안의 침식특성에 대하여 분석하고자 한다. 분석 방법은 충청남도 서해안의 4개 시 군 29개 지점을 대상으로 1년여에 걸쳐 수행된 현장조사 결과를 바탕으로 서해안의 침식 현황을 파악하고, 기 조사된 서해안 지역의 침식에 대한 자료를 바탕으로 침식원인을 유형화하였다. 조사 분석결과 서해안의 대표적인 침식유형은 직립 급경사 호안구조물의 반사파로 인한 해빈침식(자갈화), 사구 토사포락, 직립 급경사 호안구조물 저면 세굴에 의한 호안구조물 붕괴, 방파제 설치에 의한 침식 등 대표적인 4가지 유형으로 분류할 수 있으며, 침식 유형별 발생지점 수는 총 29개 지점 중 각각 19개 지점, 13개 지점, 5개 지점, 4개 지점에서 나타났다. 이는 호안구조물이 미설치된 곳은 사구 토사포락에 의한 침식 발생빈도가 높았고, 반면에 호안구조물이 설치된 곳에서는 호안구조물의 기능 상실로 인한 해빈침식의 발생빈도가 높은 것으로 나타났다. 또한 조사지점으로 선정하였던 29개 모든 지점에서 토사유실로 인한 자갈화가 진행되어 서해안의 갯벌, 사구, 해안습지 등이 유실되고 있는 것으로 나타났으며, 이는 최근 기후변화에 따른 해수면 상승과 서해안 특성을 고려하지 않은 정형화된 직립 급경사 호안구조물의 역효과로 피해가 발생된 것으로 나타났다.