• Korean Journal of Biological Psychiatry
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• v.16 no.2
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• pp.69-75
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• 2009

Objectives : The detrended fluctuation analysis is one of the nonlinear methods for the investigation of biological time series. It quantifies the fractal scaling properties and is known to be useful in the evaluation of long-range correlations in time series. The heart rate variability(HRV) of obstructive sleep apnea syndrome (OSAS) patients during nighttime was analyzed by detrended fluctuation analysis to assess its relationship with the severity of the symptoms. Methods : Fifty nine untreated male OSAS patients with moderate to severe symptoms(mean age=45.4${\pm}$11.7 years, apnea-hypopnea index, AHI${\geq}$15) underwent nocturnal polysomnography. Moderate(AHI=15-30, N=22) and severe(AHI>30, N=37) OSAS patients were compared for the indices derived from detrended fluctuation analysis and frequency domain analysis of HRV. Results : In the detrended fluctuation analysis, the alpha values were 0.75${\pm}$0.11 and 0.82${\pm}$0.07 for the severe and the moderate OSAS groups respectively. The difference was significant(p<.01). The alpha value had negative correlation with AHI(r=-.425, p=.001). Negative correlation coefficients were also found in the relationships between the alpha values and very low frequency(VLF)(r=-.425, p=.001), low frequency(LF)(r=-.633, p= <.001) and the LF/HF ratio(r=-.305, p=.019) respectively. LF/HF ratio(p=.005) was higher in the severe OSAS group compared to that of the moderate OSAS group. Conclusion : In this study, the detrended fluctuation analysis showed the significant difference between the two OSAS groups classified according to their severity of symptoms. The scaling exponent showed the negative correlation with AHI and indicies of frequency domain analysis. This result suggests that detrended fluctuation analysis can be helpful to estimate the severity of OSAS.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.275-278
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• 1997

Standard methods estimating the power spectral density(PSD) from an irregularly sampled cardiac event series require deriving a new evenly-spaced signal applicable to those methods. To avoid that requirement, in this study, the power spectrum of heart rate variability was estimated by Lomb-Scargle's algorithm, which is a means of obtaining PSD estimates directly from irregularly sampled timeseries observed in astronomy. To assess the performance of Lomb-Scargle algorithm in the power spectral analysis of heart rate variability, it was applied to various cardiac event series derived through integral pulse frequency modulation model(IPFM) simulation and from real ECG signals, and the resultant power spectra was compared with those obtained by a conventional method based on the FFT. In result, it is concluded that Lomb-Scargle's periodogram is very effective in the power spectral analysis of heart rate variability, especially in the presence of arrhythmia and/or dropouts of cardiac events.

• Journal of Biomedical Engineering Research
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• v.18 no.1
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• pp.37-44
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• 1997

In this paper, the power spectral analysis of heart rate variability(HRV) was performed to evaluate effects of orthostatic stress with head-up tiIt on autonomic nervous system(ANS) for 25 healthy male subjects(age : 24 $\pm$ 5 yr.) and a new method was proposed to assess the autonomic balance. The ECG and respiration signals were recorded at tiIt angles of $0^{\circ}$, $45^{\circ}$, $90^{\circ}$and $0^{\circ}$ successively for 10 minutes per each stage under the condition of frequency controlled respiration(0.25Hz). Heat rate(HR) gradually increased ils the angle increased Similarly, according to the increment of angle, normalized low frequency component(0.05-0.15Hz) gradually increased, whereas normalized high frequency component (0.20-0.30Hz) was reduce4 From these results it is speculated that orthostatic stress head-up tiLt, results in the prevalence of sympathetic tone in autonomic balance with the increment of sympathetic tone and the decrement of parasympathetic tone, which seems to meanthat autonomic nervous system plays a major role in compensating for disturbances of cardiovascular system due to it.

• Journal of the Korean Society of Radiology
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• v.10 no.4
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• pp.285-290
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• 2016

The purpose of our study was to retrospectively evaluate the cause of a decreased calcium score of follow-up studies on coronary artery calcium scores (CACs) computed tomography (CT). The subjects were healthy 100 people(85 males $60.6{\pm}6.9$ years, 15 females $67.2{\pm}7.3$ years). The subjects decreased CACs were divided into 4 subgroups depending on Agatston classification, minimal (1-10), mild (11-100), moderate (101-400), severe (400<). As a result of decreased CACs were scan location disagreement 51%, motion artifact 26%, equipment changes 14%, operator mistakes 5%, input miss 2%, image loss 1%, arrhythmia 1%. In the mild group, the most common decreased CACs were 49 people. In the minimal group, the most significant variation reduction has occurred to 6 people. Scan location disagreement was considered a partial volume effects due to the scan starting position. It showed less than 100 CACs a high variation (19.7%) in more than 100 CACs, a lower variation (2.2%), these could be seen that the variation range is different that can be tolerated according to the calcification score. Motion artifact factor was found in 26%, which is so closely related to the preceding tests that affect the higher heart rate like this pulmonary function test, exercise stress test.

• Journal of Yeungnam Medical Science
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• v.24 no.2
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• pp.206-215
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• 2007

Background : The prone position is often used for operations involving the spine and provides excellent surgical access. The complications associated with the prone position include ocular and auricular injuries, and musculoskeletal injuries. In particular, the prone position during general anesthesia causes hemodynamic changes. To evaluate the cardiovascular effects of the prone position in surgical patients during general anesthesia, we investigated the effects on hemodynamic change of the prone position with the Jackson spinal surgery table. Materials and Methods : Thirty patients undergoing spine surgery in the prone position were randomly selected. After induction of general anesthesia, intra-arterial and central venous pressures (CVP) were monitored and cardiac output was measured by $NICO^{(R)}$. We measured stroke volume, cardiac index, cardiac output, mean arterial pressure, heart rate, CVP and systemic vascular resistance (SVR) before changing the position. The same measurements were performed after changing to the prone position with the patient on the Jackson spinal surgery table. Results : In the prone position, there was a significant reduction in stroke volume, cardiac index and cardiac output. The heart rate, mean arterial pressure and CVP were also decreased in the prone position but not significantly. However, the SVR was increased significantly. Conclusion : The degree of a reduced cardiac index was less on the Jackson spinal surgery table than other conditions of the prone position. The reduced epidural pressure caused by free abdominal movement may decrease intraoperative blood loss. Therefore, the Jackson spinal surgery table provides a convenient and stable method for maintaining patients in the prone position during spinal surgery.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.194-199
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• 2001

쾌적한 스포츠웨어는 기능성에 있어서 자연환경의 변화조건과 인체의 운동 및 활동에 맞추어 열절달 및 수분전달 등을 적절히 조절할 수 있어야 한다. 이에 본 연구에서는 일반환경조건 및 강우환경조건하에서의 형상기억 투습방수직물 소재의 스포츠웨어 착용에 따른 인체생리반응 및 쾌적감을 규명하기 위하여 스포츠웨어를 제작하여, 인공기후실에서 환경조건변화에 따른 온열생리학적 특성 및 주관적 감각을 측정, 그 특성을 비교, 고찰하였다. 평균피부온은 강우환경조건에서 온도가 낮게, 변동폭이 많게 나타났다. 변화경향을 운동부하를 기점으로 온도의 상승이 나타났고, 운동 2단계에 가장 높은 온도를 나타냈으며, 이후 감소하였다. 직장온은 일반환경조건에 비해 강우환경조건에서 온도의 미세한 상승을 보였다. 의복내 기후는 두 조건 모두에서 가슴부위보다 등부위의 온·습도의 변동폭이 크게 나타났고, 강우환경조건에서의 의복내 온도를 제외하고는 모두 등부위의 온·습도가 높게 나타났다. 최고 혈압은 운동의 강도에 따라 비례하여 상승하고, 최저 혈압에는 큰 영향없이 나타났으며, 변화경향은 의복내 온도의 경향과 역으로 나타났다. 평균혈압은 일반환경조건에서 6.9mmHg 높게 나타났다. 심박수는 일반환경조건에서 4.4beats/min 높게 나타났다. 강우환경조건의 주관적 감각의 평가에서, 신체에 직접 가해지는 빗물 등으로 인해 불쾌감이 증가하였고, 운동 후에는 일반환경조건과 달리 냉감이 증가하였으며, 습윤감은 최고치에 달하였다.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.239-247
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• 2019

An accurate prediction of emotion is a very important issue for the sake of patient-centered medical device development and emotion-related psychology fields. Although there have been many studies on emotion prediction, no studies have applied the heart rate variability and neuro-fuzzy approach to emotion prediction. We propose ANFEP(Adaptive Neuro Fuzzy System for Emotion Prediction) HRV. The ANFEP bases its core functions on an ANFIS(Adaptive Neuro-Fuzzy Inference System) which integrates neural networks with fuzzy systems as a vehicle for training predictive models. To prove the proposed model, 50 participants were invited to join the experiment and Heart rate variability was obtained and used to input the ANFEP model. The ANFEP model with STDRR and RMSSD as inputs and two membership functions per input variable showed the best results. The result out of applying the ANFEP to the HRV metrics proved to be significantly robust when compared with benchmarking methods like linear regression, support vector regression, neural network, and random forest. The results show that reliable prediction of emotion is possible with less input and it is necessary to develop a more accurate and reliable emotion recognition system.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1639-1642
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• 1997

In this paper, the autonomic function analysis system was designed to noninvasively assess the autonomic function of cardiovascular system. Orthostatic stress protocol was designed to stimulate the autonomic nervous system. designed protocol and analysis algorithm were evaluated by experiments for 25 normal subjects and 22 hemiplegia patients. Data were processed by usign the power spectral analysis. Nwe indexes of autonomic function, LF$_{N}$ and HF$_{N}$, were proposed and were compared with LF/HF ratio. New indexes of the sympathetic and parasympathetic activity, respectively. The IST and the DPT are balanced and have positive value for normal subjects during orthostatic stress but not for hempilegia patients. This result suggest that the IST and the DPT are used as new criteria of normal autonomic function during orthostatic stress.ess.

• Proceedings of the IEEK Conference
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• 1998.06a
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• pp.561-564
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• 1998

This paper evaluated autonomic nervous system function in 23 patients with syncope and a positive tilt test result, 21 with a negative test result, and 19 healthy controls. Indexes of heart rate variability were measured during supine resting, immediately afte rtilt-up, standing rsting, immediately before syncope and immediately after tiltdown. There were no significant differences among the groups in any of the indexes of heart rate varability over the 24-hour holter recordings. In patients with a positive tilt result, tilting gaused a decrease in low-frequency (LF) immediately before syncope and incsrease in high-frequency (HF) bands immediately before. In patients with a negative tilt result, tilting caused a decrease in low-frequency (LF) immediately before syncope and decrease in high-frequency (HF) bands immediately before, different from positive tilt results. Our findings showed that patients with vasovagal syncope have no chronic differences from normal subjects in autonomic nervous system activity, but that these patients respond differently to the orthostatic stimulus.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.185-186
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• 1998

The discrete Wigner-distribution(DWD) was implemented for the time-frequency analysis of heart rate variability signals. The smoothed cross-DWD was used to estimate time-varying power spectrum. Spurious cross-terms were suppressed using a smoothing data window and a Gauss frequency window. The DWD is very easy to implement using the FFT algorithm. Experiment show that the DWD follows well the instantaneous changes of spectral content of heart rate variability signals, which characterize the dynamics of autonomic nervous system response.