• Journal of the Korean Society of Radiology
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• v.17 no.1
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• pp.53-62
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• 2023

The purpose of this study is to find an optimized imaging technique and evaluate its usefulness by comparing and analyzing the difference in contrast enhancement of lower extremity artery according to the patient's heart rate during lower extremity Computed Tomography Angiography examination. From January 2022 to August 22nd, 139 outpatients who visited Ajou University Hospital and underwent lower extremity angio CT examination were targeted. According to the heart rate, the groups were divided into four groups: A(HR ≤65), B(65 < HR < 80), C(80≤ HR). In addition, among patients with a heart rate of 65 or less, the heart rate was considered, and the scan was divided into D, E, F group with a delay time. The time of arrival of contrast medium and the average value of contrast enhancement were compared and analyzed. As a result of quantitative evaluation, B and C groups with a heart rate of more than 65 times had better HU values in the popliteal artery than A group (HR ≤ 65), and D group showed better HU improvement effects compared to A group (p<0.001). The comparative analysis with other groups was insignificant. The difference in heart rate affected the angiographic intensity of the lower extremities artery. Therefore, it is effective to apply the appropriate test timing for each patient by using the heart rate during the lower extremity angio CT Scan.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.3
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• pp.723-728
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• 2010

This study proposed a design of a portable device for measuring heart rate using photoplethysmograph signal to minimize load of a nurse increased from insufficiency of an internal hospital nurse, and algorithm to measure reliable heart rate in PPG signals despite the existence of patient's motion artifacts. The proposed method for measuring heart rate is the method to minimize the motion interference by using the adaptive filter based on harmonic characteristic of PPG signal. To evaluate the performances of the a portable device implemented by the proposed method, we used several motion artifacts including finger and wrist movements; we then compared out results with the performance of the moving average filter. In this results, the proposed method showed a better performance than that of the moving average filter. Therefore, when nurses use the a portable device for measuring heart rate proposed in this study, it will enable to improve nurse work and to measure the reliable heart rate.

• Journal of Sasang Constitutional Medicine
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• v.13 no.1
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• pp.70-78
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• 2001

ADR유발성 심근독성에 대한 심근세포의 손상기전을 규명하기 위해 ADR의 독성을 MTT정량, NR정량, LDH활성도 및 심박동을 측정하였다. 배양된 심근세포에서 청심연자탕 전탕액의 심근세포 보호효과는 LDH활성도 측정과 심박동 측정을 통해 관찰할 수 있었다. 이 실험을 통해 다음과 같은 결과를 얻을 수 있었다. 1. ADR은 배양심근세포에서 세포의 생존능력을 떨어뜨렸고, LDH의 활성도를 높였으며, 심박동수를 감소시켰다. 2. 청심연자탕 전탕액은 배양심근세포에서 ADR에 의해 증가된 LDH 활성도를 유의하게 감소시켰다. 3. 청심연자탕 전탕액은 배양심근세포에서 ADR에 의해 감소된 심박동을 유의하게 증가시켰다. 이상의 결과를 통해 ADR은 신생 마우스에서 적출해낸 배양 심근세포에서 독성효과를 나타냈음을 알 수 있었으며, 청심연자탕 전탕액은 ADR에 의해 유발된 심근세포독성에 매우 효과적으로 방어효과를 나타냄을 알 수 있었다.

• Journal of Chest Surgery
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• v.31 no.4
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• pp.398-401
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• 1998

A 56-year-old female with a permanent unipolar pacing(VVI) system underwent elective coronary bypass surgery and mitral valve replacement. Because the unipolar sensing is subject to considerable nonmyocardial electrical noise, the pacing function may be disturbed by the use of electrocautery. Temporary atrial and ventricular bipolar epicardial leads and external generator were used for maintaining A-V sequential pacing during the use of electrocautery. Before aortic cross-clamp was released after cardiac operation, regular cardiac rhythm could spontaneously be resumed with an integrated cardioplegic strategy, avoiding the use of defibrillator

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.8
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• pp.1431-1437
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• 2016

In mobile healthcare device, when to measure the heart rate by using the PPG signal, its performance is reduced according to the motion artifacts that is the movement of user. This is because the frequency range of motion (0.01-10 Hz) and that of PPG signals overlap. Also, the motion artifacts cannot be rectified by general filters. To solve the problem, this paper proposes a method using filter banks and independent component analysis (ICA). To evaluate the performance of the proposed method, we were artificially applied various movements and compared heart rate errors of the moving average filter and ICA. In the experimental results, heart rate error of the proposed method showed very low than moving average filter and ICA. In this way, it is possible to measure stable heart rate if the proposed method is applied to the healthcare terminal design.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.438-440
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• 2009

사람의 심박동은 심장 상태와 구조, 나이 등의 여러 요소에 의하여 고유한 특성을 갖고, 이러한 특성을 이용하여 개인 인증에 심박동을 적용할 수 있다. 본 논문에서는 기존의 심전도(ECG, electrocardiogram) 방법을 대신하여 빛을 이용한 광전용적맥파(PPG, Photo Plethysmogram)를 측정, 신호를 분석하였다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.05a
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• pp.349-352
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• 2009

최근 유비쿼터스 헬스케어가 부각됨에 따라 심장의 활동상태를 보다 편리하게 측정하기 위하여 이동성 및 휴대성을 강조한 심전도 계측 시스템 및 스트레스 상태를 분석하기 위한 연구들이 수행되고 있다. 하지만 기존 심전도 계측은 전극의 부착 및 계측시스템과의 연결을 위한 리드선의 사용으로 인해 활동의 불편함을 유발한다. 본 연구에서는 기 연구 수행된 가정 또는 사무실에서 무구속적인(unconstrained) 방법으로 지속적인 심장의 활동상태의 모니터링이 가능한 무구속 의자형 심탄도 계측 시스템을 구현하였다. 무구속적인 방법으로 심탄도 신호를 계측하고 심탄도신호로부터 심박동변이율을 추출함으로써 일상생활 중 스트레스를 모니터링 하고자 하였다. 구현된 시스템을 통한 스트레스 모니터링의 가능성을 평가하기위하여 안정상태의 심박동변이율과 인위적인 신체적 스트레스인 Valsalva 조작를 유도한 후 심박동 변이율을 비교평가 하였다. 건강한 대학생 10명을 대상으로 비교분석을 수행한 결과 안정 상태와 육체적 스트레스 인가 후 심박동 변이율의 변화 양상을 관찰할 수 있었으며, 무구속적인 방법에 의해 스트레스의 모니터링이 가능함을 확인 할 수 있었다.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.8
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• pp.18-26
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• 2015

Measuring the heart rate during exercise is important to properly control the amount of exercise. With the recent advent of smart device usage, there is a dramatic increase in interest in devices for the real-time measurement of the heart rate during exercise. During intensive exercise, accurate heart rate estimation from wrist-type photoplethysmography (PPG) signals is a very difficult problem due to motion artifact (MA). In this study, we propose an efficient algorithm for an accurate estimation of the heart rate from wrist-type PPG signals. For the twelve data sets, the proposed algorithm achieves the average absolute error of 1.38 beat per minute (BPM) and the Pearson correlation between the estimates and the ground-truth of heart rate was 0.9922. The proposed algorithm presents the strengths in an accurate estimation together with a fast computation speed, which is attractive in application to wearable devices.

• The Korean Journal of Pharmacology
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• v.23 no.1
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• pp.9-14
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• 1987

The effects of acebutolol and carbamazepine on ouabain-induced arrhythmias were investigated in rabbits. Ouabain produced ventricular arrhythmias which persisted for 7-8 min at the mean dose of $69{\pm}1.3\;{\mu}g/kg$. Ouabain arrhythmias were converted to normal sinus rhythm by administration of acebutolol or carbamazepine singly but lower dosages increased the recovery time. And then, ouabain arrhythmias were effectively converted to normal sinus rhythm and prevented by combined administration of carbamazepine and acebutolol. Each of the combined doses was ineffective when given singly. From the above results, it may be concluded that carbamazepine and acebutolol inhibited the ouabain-induced arrhythmias depending on the level of dosage and showed synergistic interaction.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1826-1829
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• 2015

본 연구는 측정된 심전도와 광용적맥파의 박동특징점을 무결하게 검출하기 위한 프로그램 개발에 관한 것이다. 개발된 프로그램은 생체신호 계측기에서 측정된 생체신호 데이터를 자동 및 수동으로 분석하여 박동특징점의 시간 및 값 정보를 추출 및 저장하는 프로그램으로, 측정된 파형 및 검출된 특징점 위치, 인접한 특징점간 시간 간격을 시각적으로 전달할 수 있는 GUI(Graphic User Interface)를 포함한다. 개발된 프로그램은 기존 연구에서 제시된 심박동, 맥파의 박동 특징점 거출 알고리즘을 사용하여 최초 검출을 수행하고, GUI와 연동되는 컨텍스트 메뉴를 통해 오검출 또는 미검출 정보를 효율적으로 수정할 수 있도록 함으로 비전문가에 의한 쉽고 효율적인 사용이 가능하다.