• The korean journal of orthodontics
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• v.28 no.6 s.71
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• pp.981-989
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• 1998

Positions, angulation and mesiodistal dimension of lower incisors are important in esthetics, occlusion and post-treatment stability of tower arch. When lower incisor is congenitally missing, problems such as increased overjet and overbite, closing in of adjacent teeth and size/space discrepancies may occur. When creating treatment plans, incisor position and angulation, lip support, anteroposterior skeletal relationship canine-molar relationship, overjet overbite, remaining growth potential, crowding and anterior tooth ratio have to be considered. For an accurate analysis of incisal size discrepancy, diagnostic model set-up may be helpful. The two patients in this presentation both had two lower incisor missing, but the degree of crowding, skeletal relationship, lip support, molar relationship are different and therefore treatment plan was different as well. Long term follow-up may be necessary for stability and retention.

• Journal of the Korean Society of Costume
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• v.57 no.4 s.113
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• pp.143-158
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• 2007

This study considers enlargement phenomenon in hair style as one of Costume types and analyzes its artistic characteristics based on the comparison between Hair style in the late Chosun Dynasty and that of the Rococo. First, its formative property, one of the common aesthetic characteristics, breaks the concept of traditional balance in Clothing and emphasizes its transformation, changes, and space beauty. This formative property shows the Enlargement and exaggeration beyond the concept of Space. Its sensuous property reflects women's psychological minds; exaggeration and sensualism. Artistic property doesn't focus on hair style only or clothing style only and considers hair style as renter of beauty as well as its important element. It shows the traditional beauty of nature and creativity in the Chosun Dynasty. Second, its formative property, one of the differential aesthetic characteristics, shows these following differences considering the aesthetic characteristics in the late Chosun Dynasty and that of the Rococo; mutual transformation, independent transformation, focus on distortion, harmony in scale, disharmony between irregularity and exception, extension and separation in space, etc. Sensuous property shows the temperate beauty and metaphorical sense, affected by the Practical Science, in the late Chosun Dynasty while it shows the secular sense and exaggerated beauty, affected by the Enlightenment, in the Rococo. Artistic property shows the harmony with the Clothing style, balanced wearing lines, and natural beauty, as one part of Clothing, in the late Chosun Dynasty. However it shows creativity, as separate part from Clothing, in the Rococo.

• Korean Journal of Pharmacognosy
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• v.49 no.1
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• pp.47-54
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• 2018

Astilbe rubra (AR) is a perennial, belongs to the Saxifragaceae family, it contains tannin and triterpene. AR has been used in republic korea to improve toxication, fever, pain and convulsion. Recently, number of natural products have been analyzed for potential pharmacological activities including anti-cancer, anti-obesity and anti-diabetic medication. Consequently, we investigated the growth inhibition effect of Astilbe rubra water extract (WAC), ethanol extract (EAC) and bergenin on Hela cell (human adenocarcinoma cell). From whole plant of A. rubra, bergenin was isolated by column chromatography and its structures were identified by $^1H$, $^{13}C$ NMR and IT TOF-ESI MS. High extraction efficiency of bergenin was shown at 0.95% under 60 min reflux extraction with 50% MeOH. The MTS assay showed that EAC (ethanol extract) treatment increased cell death in a dose-dependent manner. Moreover, EAC treatment on Hela cell increased apoptotic cell death and caspase-3 activity. Results suggest that EAC has growth inhibition effect on Hela cells, but not WAC and bergenin. $500{\mu}g/mL$ EAC treatment inhibited Hela cell at $60.2{\pm}1.5%$.

• Korean Journal of Pharmacognosy
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• v.47 no.3
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• pp.211-216
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• 2016

In the course of our continuing search for biologically active components from Korean medicinal plants, we isolated the main compound, luteolin 5-glucoside from aqueous fraction of Ajuga spectabilis. The structure was elucidated by the basis of $^1H$ and $^{13}C$ NMR and TOF ESI-MS data. Quantitative analysis of luteolin 5-glucoside was carried out on a XBridge C18 column ($S-5{\mu}m$, $4.6{\times}250mm$) with gradient elution composed of acetonitrile:water. The results exhibit that the average content of main compound in A. spectabilis were 0.048%. Oxidative stress plays a major role Alzheimer's disease (AD) and other neurodogenerative disease. AD is major health problem and there is currently no clinically accepted treatment to cure or stop its progression. Pretreatment with luteolin 5-glucoside markedly attenuated $H_2O_2$-induced cell viability loss in a dose-dependent manner. Luteolin 5-glucoside also inhibited the formation of intracellular reactive oxygen species in SH-SY5Y. The results suggest that luteolin 5-glucoside from A. spectabilis has protective effects against oxidative stress-induced cytotoxicity, which might be a potential therapeutic compound for treating and/or preventing neurodegenerative disease implicated with oxidative stress.

• Korean Journal of Pharmacognosy
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• v.49 no.2
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• pp.138-144
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• 2018

Asparagus oligoclonos is one of the endemic halophytes used folk medicine in Korea. We isolated the main compound rutin from methanol extracts of A. oligoclonos based on nuclear magnetic resonance and TOF ESI-MS data. We have investigated the quantitative analysis method of main compound using HPLC and the results exhibit that rutin content of A.oligoclonos were 1.816%. To explore anti-oxidant from A. oligoclonos ethanol extracts (AOE), we investigated the antioxidant effects of AOE on $H_2O_2$-induced oxidative stress in RAW 264.7 cell. AOE were reduced $H_2O_2$-induced oxidative stress via enhancement of cell viability, and AOE significantly decreased ROS production depending on concentration. Next, to screen for anti-inflammatory activity of AOE, we investigated the inhibitory effects of AOE in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. AOE had no effect on cell viability at a concentration of $500{\mu}g/mL$. Nitric oxide (NO) production inhibited in a dose-dependent manner. These results suggest that AOE may be a useful antioxidant and anti-inflammatory agent.

• Archives of design research
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• v.16 no.1
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• pp.251-260
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• 2003

The fact that office environment is a principal factor affecting work efficiency is widely accepted. Under such a circumstance, developing relocatable office wall systems is highly required. Psychological, physiological, and economical factors, along with physical factors, should be considered to develope a office wall system. More specifically, competitive price, relocatable efficiency, structural stability, fast installation, health and safety, and aesthetic satisfaction are typical determinants. The evaluation results of newly developed wall system are as below: 1) Panel structural system added with the merits of frame structural system can be studied to accomplish minimal disruption to workplace and better finish details. 2) To cover up the existing interior defects such as uneven floor and ceiling, flexible solutions must be studied especially when panel structural system is accepted. 3) More consideration must be given to finish materials, section details, sound blocking and absorbtion to enhance the satisfaction level.

• Restorative Dentistry and Endodontics
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• v.23 no.2
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• pp.647-655
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• 1998

심미도재수복시의 와동의 폭과 교두의 capping이 응력의 분포에 미치는 영향을 비교하기 위하여 연속사진 촬영술을 이용하여 상악제1소구치의 3차원 유한요소 모델을 제작하였다. 법랑질, 상아질, 도재 및 복합레진시멘트의 각각의 재질에 대한 물성치를 부여하고, 140N의 하중을 가하여 Super SAP 프로그램으로 해석하여 다음과 같은 결과를 얻었다. 1. 응력은 탄성계수값이 큰 법랑질과 도재를 따라 분포되고, 연질의 상아질에는 적게 발생된다. 2. 와동의 협측치수선각부위에서는 인레이모델의 경우에는 와동폭의 증가에 따른 응력의 증가는 관찰되지 않으나, 온레이모델에서는 응력의 증가가 관찰된다. 3. 온레이모델의 경우에는 근심협측교두를 피개하고 있는 도재부위에 최대주응력이 크게 나타나고, 치은변연부의 도재에서는 교두를 피개하지 않은 인레이모델의 해당되는 법랑질에 비해 응력이 1/2정도로 감소된다. 4. 하중이 증가되면 잔존치질의 파절은 근심와동의 협측치은선각부위에서 협측보다는 치은을 향해 경사지게 일어날 것이다. 5. 교두를 피개하면 교두피개부위에서의 도재의 파절가능성은 증가되고, 치은변연에서는 도재와 하부의 치질의 파절가능성은 감소된다. 6. 도재를 이용하여 교두를 피개할 경우에는 응력을 견딜 수 있는 도재의 두께를 부여할 수 있도록 교두를 충분히 삭제하여야 하고, 충분한 강도를 갖는 도재를 선택하여야 한다.

• Journal of Internet Computing and Services
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• v.18 no.6
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• pp.93-100
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• 2017

In multi-media, multi-channel era, video viewing using various digital devices via the Internet, not the existing broadcasting network, is emerging as a new broadcasting viewing behavior. OTT service is regarded as the main service of this change of viewing behavior. It is a video service that can seamlessly use any content desired by the user at any time, at any time, any device, any contents, if the Internet connection is available. The purpose of this study is to investigate the factors affecting the satisfaction of OTT service by applying the technology acceptance model (TAM). As a result of analyzing through 303 questionnaires of the early users of OTT service, social pressure, perceived popularity, perceived cost, user reputation, individual innovation, and esthetics set as external factors in this study are partially affects perceived usefulness, perceived ease of use, and perceived enjoyment. In addition, perceived usefulness, ease of use, and enjoyment are directly influencing satisfaction. Based on these results, we discuss the theoretical and practical implications and propose future research direction.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.21 no.4
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• pp.407-413
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• 1999

Maxillary duplication is a kind of proliferative neurocristopathy and considered to arise from bifurcation of neural crest elements soon after migration into mandibular arch. Sometimes this malformation is accompanied with oblique facial cleft. Usually this type of maxillofacial malformation requires multiple surgical intervention and the results are far from ideal. It became more troublesome if it had not been properly corrected on time, because secondary deformities could be developed from growth and development of abnormal tissues. This is a case of a 25-year-old-female patient who showed severe facial asymmetry thought to secondary deformity of maxillary duplication and masticatory disturbance due to multiple supernumerary teeth on posterior part right maxilla. We successully treated these deformities through four times of surgery of bone resection, orthodontic treatment, zygomatic and orbital reconstruction, orthognathic surgery and scar revision... ect. So we reported this rare case with review of literatures.

• The korean journal of orthodontics
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• v.26 no.2 s.55
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• pp.197-204
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• 1996

This study was performed to mark the criteria of the eathetic smile that was necessary to improve the esthetic problem in oral maxillo-facial region. The facial straight photographs of 62 adults(30 males, 32 females : 19-24 years old) in resting position and during smile were taken. The measurements and proportion of lip-teeth relationship during smile were statistically analyzed with photogrammetry. The following results wow obtained : 1. In the evaluation of the change of lips, smile line ratio was 0.93, buccal corridor ratio was 0.63, and smile symmetry ratio was 0.96. 2. The width of mouth during smile was 1.31 times of the width inthe resting position and 0.48 times of face width. 3. The upper lip height during smile was 0.69 times of the height in the resting position and the lower lip height during smile was 0.93 times of the height in the resting position. 4. The mean exposed lenght of upper central incisor was 9.96mm. Maxillary incisor exposure was significantly correlated with the upper lip change ratio, mouth width change ratio, and buccal corridor ratio.