• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.267-272
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• 2015

'Tight junctions (TJ)' have recently been identified in the granular cell layer of the human epidermis, where they contribute to the normal adhesion between keratinocytes and to the physiologic barrier function of the epidermis. Among the TJ proteins in the epidermis, occludin is an important transmembrane protein, which is considered as a major component. The purpose of this study is to investigate whether regional variation exists in the expression of the tight junction protein occludin in normal human epidermis. Indirect immunofluorescence staining for occludin was performed with specimens taken from different areas of normal skin (4 from each of 7 different anatomical sites, including the scalp, face, posterior neck, upper arm, abdomen, lower back, and inner thigh). The degrees of the expression-intensity in each specimen were estimated with the reciprocals of positive end-point titer of occludin in an indirect immunofluorescence study. The highest degree expression-intensity of the TJ protein occludin among the different areas of normal epidermis was observed on the face and abdomen with a titer of 600 (p=0.001). The lowest intensity of expression of occludin was seen in the epidermis from the upper arm. Skin specimens from the scalp, neck, back, and leg demonstrated intermediate degrees of the expression in intensity. The expression of occludin in the skin samples obtained from different locations of the body showed a statistically significant variation. This suggests that there is a certain degree of regional variation in the expression-intensity of TJ protein 'occludin' in the human epidermis.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.2
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• pp.181-188
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• 2022

The skin protects the body from excessive water loss and the invasion of harmful substances, such as chemicals and microbes. The stratum corneum, is recognized as a very important physical barrier. However, in recent years evidence emerged that tight junctions (TJ) might also play a crucial role in barrier function of the skin. In the present study, TJ proteins including transmembrane proteins and plaque proteins, skin permeability barrier function and skin diseases of TJ were reviewed.

• Journal of Life Science
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• v.18 no.9
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• pp.1230-1238
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• 2008

The purposes of this study was to identify the effects of regular training on body composition, bone mineral density and growth factors by taekwondo training program in the children. Subjects were aged 11$\sim$13 years. There was classified two groups (experiment group 12, control group 12), total 24. Measured items for this study were body composition (weight, percent body fat, body mass index), lumbar (L2, L3, L4), femur (neck, trochanter, ward's triangles) bone mineral density and growth factors (growth hormone, IGF-I, IGFBP-III) in the 12weeks before and after. Results of this study were as follows; In the body composition, there were showed significant differences on the weight, percent body fat and body mass index level between groups. In the bone mineral density, there were showed significant differences on the lumbar 2, 3, and femur neck, femur trochanter, femur ward's triangles level between groups. In the growth factors, there were showed significant differences on the growth hormone, IGF-I, and IGFBP-III level between groups. This study showed that an 12weeks taekwondo training program affected in a positive effects in almost of items in trained children.

• Journal of Life Science
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• v.19 no.11
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• pp.1605-1610
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• 2009

The purpose of this study was to investigate the effects of combined exercise program and garlic pill intake on Body Composition, CRP and Adiponectin in obese high school male students. Twenty-one male students in city B volunteered to participate, and the signed consents were received before the study. Experimental groups were garlic pill intake with combined exercise group (n=7), combined exercise group (n=7), control group (n=7). The total experimental period was 16 weeks. The combined exercise group exercised 3 times a week for 16 weeks with intensity of RPE 7~15. Each exercise was 70 minutes long. A 5 g garlic pill was consumed after lunch and dinner every day. For statistics, two-way repeated test within the group was conducted through SPSS 12.0; for post-examination, Scheffe was utilized; and for inter-group examination, a paired t-test was used. The conclusions of this study are as follows. Between groups, combined exercise with garlic pill group had a significant decrease in %body fat. Within each group, combined exercise with garlic pill group had a significantly greater decrease in %body fat than the control group. Between groups, combined exercise with garlic pill group had a significant decrease in LBM. Between groups, combined exercise with garlic pill group had a significant decrease in CRP. Between groups, combined exercise with garlic pill group, combined exercise and control group showed a decrease in adiponectin. In conclusion, regular exercise and garlic pill intake improved % body fat in obese high school male students.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.4
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• pp.373-380
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• 2019

There are many differences in tran-epidermal water loss (TEWL), skin water contents, and skin elasticity, etc between face and forearm skin. In particular, our previous studies showed that elasticity of face skin was significantly differed from forearm depending on full hydration. So, we have studied the surface properties of corneocyte using atomic force microscopy (AFM), assuming that the differences between face and forearm skin would be associated with the surface properties of corneocyte. The surface roughness of corneocyte and villus-like projections (VPs) were measured. Furthermore, qualitative comparison among the surface of face, forearm, and lip corneocyte was performed. Corneocytes were collected by tape-stripping on both face and forearm of 8 volunteers, and the bottom surface of corneocytes were measured at 40 ㎛ × 40 ㎛ using AFM. Results showed that the lower surface roughness of face corneocytes was 388.34 ± 86.189 nm, and that of forearm corneocytes was 662.27 ± 224.257 nm, which confirmed that the lower surface of forearm corneocytes was more rough than that of face corneocytes (p < 0.001). Compared with the amount of VPs, lip corneocytes were the highest followed by face corneocytes, and forearm corneocytes were the lowest. From these results, it is conclued that the surface properties of corneocytes are somewhat involved in the property differences between the face and the forearm skin and VPs can be a useful parameter for the study of corneocyte by site. In addition, AFM is a very useful device for the comparative study of nano-structural differences on the surface of corneocytes. More studies can lead to develop a new evaluation method of corneocytes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.7043-7052
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• 2015

This study divides subjects into people with metabolically healthy obesity and those with metabolically unhealthy obesity to identify the physical activities and nutrients influencing adults with obesity. Participants in the sixth Korea National Health and Nutrition Examination Survey conducted from January through December 2013 were selected as the subjects, and an analysis of complex survey samples was conducted with them. It was found that the number of days of a flexibility exercise (Odds ratio (OR)=1.18, 95% confidence interval (95% CI)=1.01-1.38), water intake (OR=1.04, 95% CI=1.01-1.06) and protein intake (OR=1.07, 95% CI=1.02-1.13) for one week were higher in people with metabolically healthy obesity than in those with metabolically unhealthy obesity, while their fat intake (OR=0.99, 95% CI=0.98-1.00)and carbohydrate intake (OR=0.98, 95% CI=0.97-0.99) were lower. Based on the results of this study, it was found that nursing intervention for obesity would need an approach according to the metabolic condition of obesity.

• Journal of Korean Clinical Nursing Research
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• v.18 no.1
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• pp.13-28
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• 2012

Purpose: This study was conducted to develop standards ensuring nursing process-based fluid intake/output and tube care, and to develop a performance measurement tool evaluating the level of care according to the standards, and finally to determine validity of the standards and the tool. Methods: The standards and the tool were reviewed by a panel of experts and refined based on the panel's suggestions. Validity of the standards and the tool were examined using a survey of 293 hospital nurses. Results: The mean validity scores of the performance measurement standards and the tool were 3.86 and 4.02, respectively, out of 5.00. So the performance measurement standards and the tool in this study were found to be acceptable in evaluating quality of nursing care for fluid intake/output and tubes. Conclusion: This result indicates that the performance measurement standards and the tool developed in this study are valid instruments to monitor and improve quality of nursing care for fluid intake/output and tube interventions, such as intravenous catheters, nasogastric tube and urinary catheters.

• Journal of Korean Society of Forest Science
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• v.113 no.2
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• pp.210-221
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• 2024

This study aimed to investigate the effects of forest walking based on an exercise prescription on body composition of older adults. Forty-four older adults (average age: 69.3 ± 3.1 years) participated in this study. The experimental group engaged in forest walking based on a prescribed exercise intensity considering the participants' respective health conditions. The participants walked three times a week for more than an hour each time for 8 weeks. By contrast, the participants in the control group spent their days according to their usual lifestyle. The analysis involved the following: ① a comparison of the measurements taken before and after the 8-week period of forest walking in the experimental group, ② a comparison between pre- and post-study measurements in the control group, and ③ a comparison of the changes (post-study minus pre-study values) between the experimental and control groups. The results were as follows: ① the experimental group showed significant decreases in weight, body fat mass, and body mass index; ② the control group exhibited significant decreases in muscle mass and ratio in right arm and left leg, muscle ratio in trunk, and body water mass in right arm; and ③ weight and body fat index decreased in the experimental group but increased in the control group. In conclusion, forest walking based on an exercise prescription had a positive impact on body composition of older adults.

• Journal of Korean society of Dental Hygiene
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• v.23 no.5
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• pp.343-350
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• 2023

Objectives: Water constitutes a majority of the human body and is essential for health. In addition, water intake can prevent dental caries by improving salivary lubrication and self-cleaning. This study aimed to determine the relationship between the amount of daily water intake and the symptoms of oral disease in Korean adolescents. Methods: We used data from the Korea Youth Risk Behavior Web-based Survey (KYRBS), conducted in Korea in 2021, and identified the relationship between daily water intake and oral disease symptoms in Korean adolescents. KYRBS is a nationwide cross-sectional survey conducted by the Korea Disease Control and Prevention Agency (KDCA), and a total of 54,848 participants were included in this study. Results: After adjusting for confounding factors, logistic regression analysis showed that tooth pain was more often experienced by those who drank less than two cups of water per day (odds ratio [OR]: 1.14; 95% confidence interval [CI]: 1.01-1.30) than those who drank five or more cups of water per day. Conclusions: A low daily water intake is associated with tooth pain, a symptom of dental caries. The results of our study suggest that increasing water intake may reduce dental caries. Therefore, adequate water intake may help prevent dental caries.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.194-199
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• 2001

쾌적한 스포츠웨어는 기능성에 있어서 자연환경의 변화조건과 인체의 운동 및 활동에 맞추어 열절달 및 수분전달 등을 적절히 조절할 수 있어야 한다. 이에 본 연구에서는 일반환경조건 및 강우환경조건하에서의 형상기억 투습방수직물 소재의 스포츠웨어 착용에 따른 인체생리반응 및 쾌적감을 규명하기 위하여 스포츠웨어를 제작하여, 인공기후실에서 환경조건변화에 따른 온열생리학적 특성 및 주관적 감각을 측정, 그 특성을 비교, 고찰하였다. 평균피부온은 강우환경조건에서 온도가 낮게, 변동폭이 많게 나타났다. 변화경향을 운동부하를 기점으로 온도의 상승이 나타났고, 운동 2단계에 가장 높은 온도를 나타냈으며, 이후 감소하였다. 직장온은 일반환경조건에 비해 강우환경조건에서 온도의 미세한 상승을 보였다. 의복내 기후는 두 조건 모두에서 가슴부위보다 등부위의 온·습도의 변동폭이 크게 나타났고, 강우환경조건에서의 의복내 온도를 제외하고는 모두 등부위의 온·습도가 높게 나타났다. 최고 혈압은 운동의 강도에 따라 비례하여 상승하고, 최저 혈압에는 큰 영향없이 나타났으며, 변화경향은 의복내 온도의 경향과 역으로 나타났다. 평균혈압은 일반환경조건에서 6.9mmHg 높게 나타났다. 심박수는 일반환경조건에서 4.4beats/min 높게 나타났다. 강우환경조건의 주관적 감각의 평가에서, 신체에 직접 가해지는 빗물 등으로 인해 불쾌감이 증가하였고, 운동 후에는 일반환경조건과 달리 냉감이 증가하였으며, 습윤감은 최고치에 달하였다.