• Title/Summary/Keyword: 신진대사 경로

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Current Research Trends in Microbial Fuel Cell Based on Polymer Electrolyte Membranes (고분자 전해질 분리막 기반 미생물 연료전지의 최근 연구동향)

  • Choi, Tae-Hwan;Kim, Hyo-Won;Park, Ho-Bum
    • Membrane Journal
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    • v.20 no.3
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    • pp.173-184
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    • 2010
  • Microbial fuel cell (MFC) is a promising renewable energy source that can generate electrical energy from organic wastes using microbe. This technology has been regarded as a future green alternative energy in that MFC makes use of organic-rich wastewater and also reduces waste sludges as well as produces electricity. To be practically realized, however, achieving higher power density than now is demanded, which may be possible by eliminating various negative factors to act as resistances in MFC operations. For instance, highly activated microbes, highly conductive electrode materials, and fast electron transfer between microbes and electrodes can lead to MFC with high power density. In particular, polymer electrolyte membranes are also a key component for improved MFC performance.

Effects of Cardiac Rehabilitation in Elderly Patients After Myocardial Infarction (노인 심근경색 환자에서의 심장재활의 효과)

  • KIM, JI HEE
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.464-471
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    • 2016
  • To investigate the effects of cardiac rehabilitation (CR) on cardiopulmonary exercise capacity in both elderly and younger patients with myocardial infarction (MI). Of the MI patients who received hospital-based CR between February 2012 and December 2015, we retrospectively reviewed the medical records of patients who continued a follow-up through the outpatient clinic. A total of 46 patients (18 elderly patients (${\geq}60years$) and 28 younger patient (< 60)) were included in this study. The subjects visited the clinic to perform aerobic exercises with ECG monitoring based on their initial exercise tolerance test outcome. The exercise capacity was measured by symptom-limited exercise tests before and after hospital-based CR. Before CR, the elderly group had a significantly lower exercise capacity in peak VO2, METs, anaerobic threshold, exercise time, respiratory exchange ratio (RER) than the younger group. After CR, elderly groups showed a significantly improved exercise capacity in exercise time, HRmax, HRrest, peak VO2, METs, anaerobic threshold, and RER. Both elderly and younger groups showed similar improvement of cardiopulmonary exercise capacity after hospital-based CR. There is a very low cardiac rehabilitation participation and referral rates with MI patients in Korea. It is considered necessary to further expand the participation of cardiac rehabilitation in elderly MI patients.

OVERVIEW OF HEALTH PHYSICS STUDIES ON TRITIUM BETA RADIATION (삼중수소 베타방사선에 관한 보건물리 연구의 적용)

  • Hwang, Sun-Tae;Hah, Suk-Ho
    • Progress in Medical Physics
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    • v.5 no.1
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    • pp.75-85
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    • 1994
  • As we enter the 2000s, there are four nuclear power units of the pressurized heavy water reactor-type in the commercial operation at the Wolsung Nuclear Power Plant(NPP) site where a larger amount of tritium ($\^$3/H) is released inevitably to the site environment. This radioctive nuclide is easily distributed throghout our environment because of its ubiquitous form as tritiated water (HTO) and its persistence in the environment. Tritum has certain characterisitics that present unique challenges for beta radiation dosimety and health risk assesment. In this paper, therefore, a variety of matters on tritium are considered and reviewed in terms of its characteristics and sources, metabolism and dosimetry, microdosimetry, radiobiology, risk assessment, and transport and cycling in the environment, etc.

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UniPath: A Knowledge Representation System for Biopathways (바이오패스웨이를 위한 지식 표현 시스템)

  • 이민수;박승수;강성희
    • Journal of KIISE:Software and Applications
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    • v.31 no.3
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    • pp.343-352
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    • 2004
  • Recently, the information processing of ever increasing bio-related data is becoming a very important issue. One of the main sources of these bio-data comes with the form of biopathways, which includes molecular transactions and processes that are part of biochemical systems. The information represented by biopathways includes various organic relations among its components. However, most of the current systems to represent biopathways have been initially developed without computer processing in mind, and hence suffer from inconsistencies and ambiguities. In this paper, we propose an improved notation, called UniPath, for clear and systematic representation of biopathways. The proposed system is designed to provide a unified representation of metabolic and regulatory pathways. We also designed and implemented a graphic editor for UniPath to draw biopathwavs map according to the proposed notation. The graphic editor is designed so that biopathway data can be easily transformed into XML format.

The ornaments modeling applied of amethyst gems and design development of interior jewel modeling (자수정(Amethyst) 보석을 응용한 장신구 조형과 Interior Jewel Modeling의 디자인 개발)

  • Kim, Eun-Ju
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.22 no.4
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    • pp.170-177
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    • 2012
  • Amethyst gems represents thermal effects of far-infrared emission, promotes the body's metabolism, and attracts attention as an eco-friendly interior material. In this paper, amethyst increase the value of jeweling by applying the characteristic purple motif, furthermore, I will intend to develop of design model. Metal crafting of brooch & necklace in the works performed based on the organic three-dimensional shape of the Rhino CAD Data. It was made possible through the precise laminated wax processing and then combining the amethyst. I researched the ornament modeling by applying the 'Golden Ratio', and suggesting utilizing method for interior jewel modeling, and also, is expected that this paper on the amethyst modeling design can contribute to the manufacturers' productivity.

A comprehensive review of microplastics: Sources, pathways, and implications (미세 플라스틱의 종합적 고찰: 근원, 경로 및 시사점)

  • Yano, K.A.V.;Reyes, N.J.D.G.;Geronimo, F.K.F.;Jeon, M.S.;Kim, Y.;Kim, L.H.
    • Journal of Wetlands Research
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    • v.22 no.2
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    • pp.153-160
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    • 2020
  • Most studies defined microplastic (MP) as plastic particles less than 5 mm. The ubiquity of MP is raising awareness due to its potential risk to humans and the environment. MP can cause harmful effects to humans and living organisms. This paper review aimed to provide a better understanding of the sources, pathways, and impacts of MP in the environment. MP can be classified as primary and secondary in nature. Moreover, microplastic can also be classified as based on its physical and chemical characteristics. Stormwater and wastewater are important pathways of introducing MP in large water bodies. As compared to stormwater, the concentrations of MP in wastewater were relatively lower since wastewater treatment processes can contribute to the removal of MP. In terms of polymer distribution, wastewater contains a wider array of polymer varieties than stormwater runoff. The most common types of polymer found in wastewater and stormwater runoff were polypropylene (PP), polyvinyl chloride (PVC), polystyrene (PS), polyethylene (PE) and polyethylene terephthalate (PET). The continuous discharge and the increasing number of MP in the environment can pose greater hazards and harmful effects on humans and other living organisms. Despite the growing number of publications in relation to MP, further studies are needed to define concrete regulations and management strategies for mitigating the detrimental effects of MP in the environment.

The Effects of High-Intensity Aerobic Interval Training In The Elderly With Myocardial Infarction (노인 심근경색 환자에서 고강도 간헐적 유산소운동의 효과)

  • Kim, Ji Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.267-274
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    • 2019
  • To investigate the effect of high-intensity interval training (HIIT) on the outcomes of cardiac rehabilitation(CR) in elderly and younger patients with myocardial infarction(MI). Of the MI patients who received hospital-based CR from 2015 to 2017, we retrospectively reviewed the medical records of the patients who continued follow-up through the outpatient clinic. A total of 39 patients (20 elderly patients (${\geq}60year$($64.1{\pm}3.6$)) and 19 younger patients (< 60 year($55.6{\pm}2.3$)) was included in this study. The HIIT program was composed of 10 minutes of warm-up, 30 minutes of interval aerobic exercise, and 10 minutes of cool down. The aerobic exercise based on their initial exercise tolerance test outcome consisted of 3-minute usual intensity phase (60-70% of heart rate/VO2 reserve) and 4-minute of high-intensity phase (70-90% of heart rate/VO2 reserve). Exercise capacity was measured by exercise tests before and after hospital- based CR. Before CR, elderly group had a significantly lower exercise capacity in Exercise time, peak VO2, METs, Anaerobic threshold, VEmax, 02pulse than younger group. Both group showed similar improvement of cardiopulmonary exercise capacity after CR. And HIIT is safe and effective in elderly patients. It is considered necessary to further expansion for the participation of high intensity interval training in elderly patients.

2,7-Phloroglucinol-6,6-Bieckol Increases Glucose Uptake by Promoting GLUT4 Translocation to Plasma Membrane in 3T3-L1 Adipocytes (2,7-Phloroglucinol-6,6-Bieckol의 3T3-L1 지방세포에서 GLUT4 활성화를 통한 포도당 흡수 증진 효과)

  • Lee, Hyun-Ah;Han, Ji⁃Sook
    • Journal of Life Science
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    • v.31 no.8
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    • pp.729-735
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    • 2021
  • Type 2 diabetes occurs when there is an abnormality in the tissue's ability to absorb glucose. Glucose uptake and metabolism by insulin are the basic mechanisms that maintain blood sugar. Glucose uptake goes through various signaling steps initiated by the binding of insulin to receptors on the cell surface. In line with the foregoing, the purpose of this study was to investigate the effect of 2,7-phloroglucinol-6,6-bieckol (PHB), an active compound isolated from Ecklonia cava, on glucose uptake in 3T3-L1 adipocytes. Notably, PHB increased glucose uptake in a dose-dependent manner owing to the enhanced glucose transporter type 4 (GLUT4) expression in the plasma membrane of 3T3-L1 adipocytes. These effects of PHB were attributed to the phosphorylation of insulin receptor substrate-1 and protein kinase B (PKB or AKT), as well as to the phosphoinositide 3-kinase (PI3K) activation in the insulin signaling pathway. PHB also stimulated 5' AMP-activated protein kinase (AMPK) phosphorylation and activation. The phosphorylation and activation of the PI3K/AKT and AMPK pathways by PHB were identified using wortmannin (a PI3K inhibitor) and compound C (an AMPK inhibitor). In this study, we showed that PHB can increase glucose uptake in 3T3-L1 adipocytes by promoting GLUT4 translocation to the plasma membrane via the PI3K and AMPK pathways. The results indicate that PHB may help improve insulin sensitivity.

Considerations for the effects of antioxidant phytochemicals on human health (산화방지제 파이토케미컬이 건강에 미치는 영향에 대해 고려할 점)

  • Kim, Dae-Ok;Lee, Chang Y.
    • Korean Journal of Food Science and Technology
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    • v.53 no.2
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    • pp.111-114
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    • 2021
  • Phytochemicals in fruits, vegetables, cereals, and nuts, advertised as "antioxidants", combat undesirable effects of reactive oxygen species (ROS) in the body. These undesirable effects include cancer, cardiovascular diseases, and neurodegenerative disorders. Although ROS were initially considered to be primarily damaging agents, ROS have been discovered to play a role in signaling immune and other physiological responses in recent years. Several studies have demonstrated that ROS act as essential signaling molecules to promote metabolic health. Therefore, the overall advantage of the interference of ROS signals by antioxidants could be questionable. Future research is required to understand the implications of the application of phytochemicals in functional foods and supplements for health benefits on ROS levels in the body. This study describes the new roles of ROS and hormesis of various phytochemicals to provide a possible research guideline to food and nutrition scientists.

Comparative Study on the Committed Dose Equivalent for Adults and Infants (예탁선양치(預託線量値)에서 본 성인(成人)과 유아(幼兒)와의 비교연구(比較硏究))

  • Sung, Kye-Yong;Yook, Chong-Chul;Ha, Chung-Woo
    • Journal of Radiation Protection and Research
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    • v.9 no.2
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    • pp.76-89
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    • 1984
  • Weighted committed dose equivalents($W_T\;H_{50}$) per intake of unit activity of four nuclides-I-131, I-133, Cs-134 and Cs-137-, which was based on the concepts of ICRP Pub. 30, are calculated for adult who is 70 kg and 25 years old and, for infant who is 10 kg and 1 year old. Metabolism of iodine taken through oral or inhalation pathway is described by using the three-compartment model which consists of inorganic, thyroid and organic compartment. After intake, the amount of iodine in every compartment is calculated by solving the transfer equations among the these compartments. As soon as caesium is taken into the body, it is distributed uniformly in the body through the transfer compartment. In this case, the amount of caesium in total body is calculated by using the total body compartment model which is divided into two tissue compartments because of their different biological half-lifes of caesium in body. As a result of calculations, whether oral or inhalation pathway, the values of ($W_T\;H_{50}$) per intake of unit activity of I-131 for infants are about ten times as much as those of adults. On the other hand, for Cs-134 and Cs-137, the values of $W_T\;H_{50}$ per intake of unit activity show that, whether adults of infants, they have almost the same values.

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