• 제목/요약/키워드: 신장 이식

검색결과 250건 처리시간 0.031초

소의 심낭 고정에서 용매 처치, 무세포화 혹은 항독성화 처치가 조직의 장력 및 신장도에 미치는 영향 (Effects on Tensile Strength and Elasticity after Treatment with Glutaraldehyde, Solvent, Decellularization and Detoxification in Fresh Bovine Pericardium)

  • 장우성;김용진;김수환
    • Journal of Chest Surgery
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    • 제43권1호
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    • pp.1-10
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    • 2010
  • 배경: 심장 혈관계 수술에서 인공 조직 보철편은 주로 소나 돼지 판막, 심낭의 글루타알데하이드 고정 방법을 사용하고 있으나 중장기적으로 이식편의 석회화 및 물리-기계적인 결함이 문제시 되고 있다. 이 중 본 연구에서는 소의 심낭에 글루타알데하이드 고정, 용매, 무세포화, 항독성화 처리가 조직의 물리-기계적 장력 및 신장도에 미치는 영향을 알아보고자 하였다. 대상 및 방법: 아무런 처리를 하지 않은 신선한 소의 심낭과 여러 방법의 글루타알데하이드 고정 및 용매 첨가 그룹, 무세포화 그룹, 항독성화 처리 그룹 등으로 나누어 각 조직의 물리-기계적 장력 및 신장도 검사를 시행하였다. 심낭을 30도 각도로 달리하여 얻어낸 6가지 방향에 대하여 폭 5 mm에 대한 인장 강도를 구하여 장력을 측정하였고, 양방향으로 늘려 끊어지는 시점에서의 길이를 측정하여 늘어난 정도를 구하여 신장도를 측정하였다. 결과: 1) 상용 농도의 글루타알데하이드 고정시 장력이 감소하며(n=83, $MPa=11.47{\pm}5.40$, p=0.006) 용매를 첨가하였을 때 장력의 변화는 관찰되지 않았다. 신장도는 글루타알데하이드 고정시 늘어났으며(n=83, strain $(%)=24.55{\pm}9.81$, p=0.00), 용매 첨가시 신장도의 변화는 관찰되지 않았다. 2) 무세포화 처리시 대부분의 장력은 감소하는 경향을 보였으며(p>0.05) 장기간 저농도 용액 처리, 고농도의 세정용매 처리시 장력의 감소가 통계적으로 유의했으며(p=0.01, p=0.00), 신장도는 늘어나는 경향을 보였다. 3) 항독성화 처리 시 장력 및 신장도에 유의한 차이를 보이지 않았다. 결론: 소의 심낭에 글루타알데하이드 고정, 용매, 항독성화 처리 후에는 장력 손실이 관찰되지 않으며 신장도는 증가하는 경향을 보였다. 무세포화에 따른 장력의 손실이 뚜렷하였으나 저 농도 세정제 사용과 고농도 용액처리를 보강한 무세포화 처리에서는 장력의 손실이 향상되었다. 계속해서 더 나은 이식 보철편개발을 위한 다양한 용매의 연구 개발이 필요하다.

신장이식 환자의 인플루엔자 예방접종 실태와 이행 영향 요인 (Current Immunization Status and Factors Affecting the Influenza Vaccination in Kidney Transplant Patients)

  • 조한경;정재심;문성미;김미나
    • Journal of Korean Biological Nursing Science
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    • 제18권2호
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    • pp.118-125
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    • 2016
  • Purpose: The present study examines the current influenza immunization rate among kidney transplant patients in an effort to identify the factors influencing their decisions pertaining to the immunization. Methods :Participants in the study included 150 adults over the age of 64 years who visited a General Surgery Department in Korea on April 2015, who had had a kidney transplant at least two years prior to the visit. We compared the characteristics of transplant patients who were immunized against those of the patients who had not been immunized. Results: The average age of the participants was $48.5{\pm}9.6years$, consisting of 87 males (58.0%) and 63 females (42.0%). The average post-surgery period was $91.0{\pm}59.0months$. Between September and December 2014, the immunization rate among these participants was 61.3%. Factors which influenced the participant's decision to get immunized in 2014 and drove up the immunization rate were: previous immunization in 2013 (OR=24.57, CI= 8.79-68.70, p<.001), marital status (OR=3.33, CI 1.05-10.56, p=.041), and awareness (OR=1.58, CI=0.99-2.52, p=.056). Conslusion: The current study found that the previous year's immunization record, marital status, and awareness increased the rate of immunization among the participants.

신장이식환자를 위한 능력증강교육프로그램 효과 (The Effects of an Empowerment Education Program for Kidney Transplantation Patients)

  • 김성희;유혜숙
    • 대한간호학회지
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    • 제47권4호
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    • pp.445-455
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    • 2017
  • Purpose: This study was conducted to develop an Empowerment Education Program (EEP) for kidney transplant patients and to test the program's effects on uncertainty, self-care ability, and compliance. Methods: The research was conducted using a nonequivalent control group with a pretest-posttest design. The participants were 53 outpatients (experimental group: 25, control group: 28) who were receiving hospital treatment after kidney transplants. After the pre-test, patients in the experimental group underwent a weekly EEP for six weeks. The post-test was conducted immediately after, and four weeks after the program's completion in the same manner as the pre-test. For the control group, we conducted a post-test six and ten weeks after the pre-test, without and program intervention. A repeated measure ANOVA was performed to compare the change scores on main outcomes. Results: Uncertainty was significantly lower in the experimental group than in the control group, both immediately after (t=-3.84, p=<.001) and 4 weeks after (t=-4.51 p=<.001) the program, whereas self-care ability (t=5.81, p=<.001), (t=5.84, p=<.001) and compliance (t=5.07, p=<.001), (t=5.45, p=<.001) were significantly higher. Conclusion: Kidney transplant patients who underwent an EEP showed a decrease in uncertainty and an improvement in self-care ability and compliance. Thus, our findings confirmed that an EEP can be an independent intervention method for improving and maintaining the health of kidney transplant patients.

체세포배 형성을 통한 서울오갈피(Eleutherococcus seoulensis) 묘목의 대량생산 (Mass-production of Eleutherococcus seoulensis Seedlings Through Somatic Embryogenesis)

  • 이수광;강호덕
    • 한국산림과학회지
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    • 제98권6호
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    • pp.719-725
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    • 2009
  • 본 연구는 체세포배를 통해 증식된 서울오갈피(Eleutherococcus seoulensis)의 기외 대량 묘목생산을 위한 최적의 조건을 구명하기 위해 수행되었다. 어뢰형의 체세포배는 $GA_3$가 각각 3.0 mg/L와 5.0 mg/L가 첨가된 1/3 MS와 WPM 배지에 치상하여 4주간 발아시켰으며 발아된 유식물체는 0.2% 활성탄과 1.0 mg/L $GA_3$가 첨가된 1/2 SH 배지에 옮겨주어 신장을 유도하였다. 신장된 유식물체는 대기순화 효과를 관찰하기 위해 membrane filter가 부착된 대기순화 용기에 치상하였다. 대기순화 처리와 더불어 토양의 종류가 야외순화에 미치는 영향을 살펴보기 위해 혼합토(펄라이트+피트모스), 펄라이트, 서울 남산상토에 이식하였고, 서울 남산상토에서 대기순화 과정을 거친 식물체가 8주 후 70% 이상 생존하였다. 토양순화 과정을 거친 묘목은 야외 묘포장에 이식하였고, 그 결과 8주 후 95% 이상생존하였다.

자기효능증진 운동프로그램이 신장이식 환자의 체중, 체지방율, 운동시간 및 심폐기능에 미치는 효과 (The Effects of the Self Efficacy Promotion and Exercise Program on the weight, body fat rate, exercise time and cardiopulmonary function of kidney transplant recipients)

  • 안재현;김남초
    • 성인간호학회지
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    • 제12권3호
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    • pp.452-462
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    • 2000
  • The purpose of this study is to develop and evaluate the Self Efficacy Promotion and Exercise Program to prevent of obesity and cardiovascular diseases for the kidney transplant recipients. The subjects were selected randomly among the patients who underwent kidney transplantations at one major transplantation hospital in Seoul, Korea. This study ws carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids therapy and did not take any physical exercise regularly. The subjects received the self efficacy promotion and exercise program for 12 weeks which contained self efficacy promotion education and exercise program. The weight, body fat rate, exercise time and cardiopulmonary function were evaluated before the experiment and after the experiment. The results were as follows: 1. After the experiment, the weight was significantly decreased than that of before the experiment(p=.0001). 2. After the experiment, the body fat rate was significantly decreased than that of before the experiment(p=.0010). 3. After the experiment, the exercise time was significantly increased than that of before the experiment(p=.0002). 4. After the experiment, the absolute VO2 was significantly increased than that of before the experiment(p=.0008). 5. After the experiment, the relative VO2 was significantly increased than that of before the experiment(p=.0002). This study showed that the self efficacy promotion and exercise program was effective. So it would be expected that this self efficacy promotion and exercise program could be applied as an effective independent nursing intervention widely in prevention of obesity and cardiovascular diseases for kidney transplant recipients.

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신장이식 환자의 근력, 근지구력, 유연성 및 일상생활활동의 변화 (The Change of Muscle Strength, Muscle Endurance, Flexibility and Activities of Daily Living of the Kidney Transplant Recipients)

  • 안재현;하희선;홍정자
    • 성인간호학회지
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    • 제13권1호
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    • pp.5-14
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    • 2001
  • The purpose of this study was to explore the change of muscle strength, muscle endurance, flexibility and activities of daily living to develop a rehabilitational program. The subjects were selected randomly among the patients who underwent kidney transplantations at one major transplantation hospital in Seoul, Korea. This study was carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids and did not take any physical exercise regularly. The muscle strength, muscle endurance, flexibility and activities of daily living were evaluated at 1st week and after 12 weeks. The data were analyzed with numbers, percentiles, mean, standard deviation and t-test. The results were as follows: 1. After 12 weeks, the grip strength was significantly decreased than 1st week (p=.0002). 2. After 12 weeks, the back lift strength was significantly decreased than 1st week (p=.0002). 3. After 12 weeks, the muscle endurance was increased than 1st week, but it was not significant(p=.5487). 4. After 12 weeks, the flexibility was significantly decreased than 1st week (p=.0002). 5. After 12 weeks, the activities of daily living was significantly decreased than 1st week (p=.0006). Like the above result, the kidney transplant receipients' muscle strength, flexibility and activities of daily living were reduced. In order to solve this problem, the writer has found that program development to prevent the defects should be extremely required. Since now on the number of patients should expand. After the kidney transplantation, the periods of 4, 8, 12 and 16 weeks are extended. The writer proposes to examine the different phase of change in each periods.

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자기효능증진 운동훈련 프로그램이 신장이식 환자의 불안, 우울 및 삶의 질에 미치는 효과 (The Effects of the Self Efficacy Promotion and Exercise Training Program on Anxiety, Depression and Quality of Life of Kidney Transplant Recipients)

  • 안재현
    • 성인간호학회지
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    • 제13권2호
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    • pp.223-232
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    • 2001
  • The purpose of this study is to develop and evaluate the Self Efficacy Promotion and Exercise Training Program to decrease anxiety and depression and to increase the quality of life for kidney transplant recipients. The subjects were selected randomly among the patients who underwent renal transplant at three major transplantation hospitals in Seoul, Korea. The observed subjects in this study consisted of 56 patients who had renal transplantations between one to twelve months prior to this study. The patients did not take any regular physical exercise. This study was carried out between November, 1999 and March, 2000. The study groups were divided into 3 groups; exercise training group (n=16), self efficacy group (n=18) and control group (n=22). The exercise training group received self efficacy promotion and exercise training program for 12 weeks. The self efficacy group received self efficacy promotion education, but no exercise training was given. The control group was not offered any education. The anxiety, depression and quality of life were evaluated 3 times, before the experiment, after 8 weeks and after 12 weeks. The data were analyzed with mean, standard deviation, Chi-square test, ANOVA and $Scheff\acute{e}$ test. The results were as follows: 1. After the experiment, anxiety and depression scores of the exercise training group and self efficacy group were more significantly decreased than those of the control group (p=.05). 2. After the experiment, the quality of life score of the exercise training group and self efficacy group were more significantly increased than those of the control group (p=.05). This study showed that the Self Efficacy and Exercise Training Programs were effective. Therefore, it is expected that the Self Efficacy Promotion and Exercise Training Program could be widely applied as an effective independent nursing intervention to decrease anxiety and depression and to increase quality of life for kidney transplant recipients.

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신장이식 환자의 교육요구와 간호사가 지각하는 교육의 중요성 비교 (A Study on the Educational Needs of the Kidney Transplant Patients and Educational Importance perceived by Their Nurses)

  • 안재현
    • 성인간호학회지
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    • 제12권4호
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    • pp.678-689
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    • 2000
  • The purpose of this study was to explore the educational needs of kidney transplant patients and educational importance perceived by their nurses to develop a rehabilitational and educational program. Data were collected from January 29, 1999 to July 30, 1999 with interviews using a structured questionnaire. The subjects for this study were 173, of whom 107 were patients who had had a kidney transplant and had visited the out-patient department and 66 were transplant ward nurses who were taking care of the kidney transplant patients at six general hospitals located in Seoul. The questionnaire used for this study was developed by the investigator through a literature review and collected and modified by 11 professional personnel and 3 kidney transplant patients. The data were analyzed using the SAS program for numbers, percentiles, mean, standard deviation, t-test, ANOVA, and $Scheff{\acute{e}}$ test. The results were as follows; 1) In the patient group, the total mean score for educational needs was 154.61 and the item mean score was 3.96. In the nurses group, the total mean score for perceived educational importance was 166.26 and the item mean score was 4.26. In the nurses group, perceived educational needs were scored higher than by the patient group. With regard to domains, both patient and nurses group had the highest educational needs and perceived educational importance in the domain of physical condition and the top five items in the educational needs and perceived educational importance were also in the domain of physical condition. 2) In the patient group, women and the divorce/bereavement group had higher educational needs in the domain of nutritional management, those who had been admitted longer than 4 weeks from their kidney transplant time had higher educational needs in the domains of physical condition and those who were less than 4 years from their transplant had higher educational needs in the domain of follow-up care. In the nurses group, those who were married had higher perceived educational importance in the domain of physical condition.

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신장이식 환자와 가족의 퇴원후 교육요구 (A Study on the Educational Needs of Patients with Kidney Transplants and their Family Members after Discharge from Hospital)

  • 안재현;김남초
    • 대한간호학회지
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    • 제29권6호
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    • pp.1324-1335
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    • 1999
  • The purpose of this study was to explore the educational needs of patients with, kidney transplants and their family members to develop a rehabilitational and educational program. Data were collected from January 29, 1999 to April 20, 1999 with interviews using a structured questionnaire. There were 184 subjects in this study. of them, 107 were patients who had kidney transplants and had visited at the out-patient department of three general hospitals located in Seoul and 77 were family members. The questionnaire used for this study was developed by the investigator through a literature review and from data collected from 11 professional personnel and three kidney transplant patients and their families. The data were analyzed using the SAS program with t-test, ANOVA, Scheff test, Pearson correlation coefficient. The results are as follows; 1) In the patient group, total mean score for educational needs was 154.61 and the item mean score was 3.96. For the family group, total mean score for educational needs was 168.84 and the item mean score was 4.15. So in the family group, educational needs were scored higher than by the patient group. With regard to domains, both patient and family groups had as the highest educational needs, the domain of physical health and the top ten items in the educational needs were also in the domain of physical health. 2) In the patient group, women and the divorce/ bereavement group had higher educational needs in the domain of nutritional management, those who had been admitted longer than four weeks from their kidney transplant had higher educational needs in the domain of physical health and those who were less than 4 years from their transplant had higher educational needs in the domain of follow-up care. In the family group, those who were Catholics and had high school education had higher educational needs in the domain of nutritional management. 3) In the patient group, academic background was positively correlated(r=.208, p=.031) to educational needs.

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신장이식 환자의 치료지시 이행정도와 교육 요구도에 관한 연구 (A study on the Compliance and Educational Demand of Renal Transplantation Patient)

  • 류정하;김명희;강인순
    • 재활간호학회지
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    • 제6권2호
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    • pp.226-238
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    • 2003
  • This study was started for the purpose of providing the basic data for continous managment of kidney transplantation patients after discharge. This study was conducted on 180 patients who received renal transplants at three hospital( B, M, P) pusan, korea. The data collection was done for june 1, to August 31, 2002. General characteristics, renal transplantaton characteristics, physical characteristics, the level of compliance and the degree of educational demand were done by the number and percentage, the mean, standard deviation. The level of compliance and educational demand followed by the characteristics of general and kidney transplantation were analyzed by t-test and ANOVA. The result were as fallows; 1. Man was higher than woman such as 60.0%, Mean age was 42.5 years old, Average total duration of after operation was 5.5 years. 2. Cases of systolic blood pressure over 140mmHg were 10.0%, cases of diastolic blood pressure over 90mmHg were 22.8% and obesity factor in BMI was 15.6%. The person who daily water intake amount is 5000cc was 0.6%, the case that daily urine output is below 1000cc was 8.9%, and the case that urine output is zero was 0.6%. 3. The mean score of compliance was 77.47 point, The score in medication part was highest such as 4.67 point, that in stress situation was lowest such as 3.50 point. 4. The average score of educational demand was 154.02 point, and physical state part was 4.36 points highest, activation part was 3.48 points lowest. As a role of nurse Confirmation of compliance is very important encourage to make good through regular hospital visitation, point out the noncompliance part and then increase compliance of renal transplantation patient As well there will be maintain the normal kidney function to satisfy educational demand through continous education.

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