• Title/Summary/Keyword: 신생물

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Primary Neurofibroma of Trachea -A case Report- (기관에 발생한 원발성 신경섬유종)

  • 김준현;송태승;김동관;박승일;손광현
    • Journal of Chest Surgery
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    • v.31 no.1
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    • pp.82-85
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    • 1998
  • Benign tumors of the trachea are rare and are usually misdiagnosed as bronchial asthma because of the similarity of the symptoms and signs. Although the prognosis of neurofibroma which originats from Schwann cells is good, it may recur or undergo malignant change, so segmental resection of the trachea is recommended. Recently, we experienced a case of primary neurofibroma of the trachea treated successfully by segmental resection of the trachea and end-to-end anastomosis. We report it with a brief review of literatures.

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작업환경을 위한 TVL의 근거 - PENTACHLOROPHENOL(1)

  • Kim, Chi-Nyeon
    • 월간산업보건
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    • s.262
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    • pp.26-29
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    • 2010
  • 펜타클로로페놀의 현재 직업적 노출기준은 $0.5\;mg/m^3$(TLV-TWA)으로 권고하고 있다. 이 수치는 눈, 점막과 상기도의 염증과 발한, 열, 위장 불만, 시각 장해, 중추 신경계와 심혈관계 장해를 유발할 수 있는 급성 독성의 가능성을 최소로 하는 것을 목적으로 설정하였다. Chloracne는 공업용 펜타클로로페놀을 사용하거나 펜타클로로페놀을 생산하는 근로자들에 대해서 보고하였다. 펜타클로로페놀은 피부를 통해서 즉시 흡수되는데, 이 물질의 조직 독성은 펜타클로로페놀을 포함한 용액이나 펜타클로로페놀로 오염된 의류와 접촉된 사람에게서 보고되었다. 따라서 피부경고주석은 적합한 것으로 판단되었다. 펜타클로로페놀의 발암성 잠재력에 대한 명확한 증거는 간세포성과 신장에 가까운 신생물이 관찰된 설치류 생물 검정에서 발견되었다. 그러므로 본 물질은 인간에게 불명확한 관련성을 가진 동물성 발암물질(A3)로 설정하였다. 충분한 자료가 확보되지 않아 감작성 (SEN) 경고주석 또는 TLV-STEL은 권고되지 않았다. 펜타클로로페놀은 생물학적 노출지수(BEIs)가 권고된 물질이다.

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Effects on the Mortality Patterns by Religious and Related Factors in Korean Population (종교 및 융복합적 특성이 사망양상에 미치는 영향)

  • Lim, Jong-Min;Jang, Ju-Dong;Kim, Hyun-Soo;Lee, Moo-Sik
    • Journal of the Korea Convergence Society
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    • v.6 no.4
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    • pp.213-223
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    • 2015
  • Objectives : Seventh-day Adventists is well known to place a strong doctrinal emphasis on healthy life style that do not consume tobacco, alcohol or pork, and many adhere to a lacto-ovo-vegetarian lifestyle. This study aimed to investigate the difference of mortality between Korean Seventh-day Adventists and the general Korean population. Methods : We got 592 mortality data of Adventist cemetery in Seoul city and Kyunggi provincce of Korea, which contains information on causes of death for 2000-2004. Also we used mortality data of the general Korean population in Korea National Statistics Office for 2000-2004. Results : The mean age at death was 70.45 in Korean Adventists, 65.63 in the general Korean population. Higher neoplasm cause of death, such as of stomach, liver and breast, were observed in Korean Adventists than the general population. The death cause of injury, poisoning and external causes, and cerebrovascular disease were higher in the general population than Korean Adventists. The death cause of stomach cancer was lower in Korean Adventists who had above 10 years religious period than general population above age 50 years. In male, the death cause of lung cancer was lower in Korean Adventists than the general population. Conclusions : The results point to the importance of healthy life-style in Korean peoples, and indicate that lifestyle changes in the population might change the causes of death.

NEED FOR DEVELOPMENT OF HOME HEALTH NURSING PROGRAM IN KOREA (가정 간호 사업에 관한 연구)

  • Ruth M. Virginia;Moon Jung Soon
    • Journal of Korean Public Health Nursing
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    • v.5 no.1
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    • pp.53-69
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    • 1991
  • 가정간호사업 도입에 대한 대상자의 필요성에 대한 인식을 알아보고자, 1988년 7월 1일부터 동년 8월말까지 서울시내 5개 대학병원에서 퇴원하는 환자 390명과 환자 보호자 380명, 주민 780명, 총 1550명을 대상으로 조사한 결과 다음과 같은 결론을 얻었다. 1. $81\%$의 대상자가 가정간호 사업 도입이 필요하다고 한 반면 $7.5\%$는 필요 없다고 하였으며, $11.5\%$는 잘 모르겠다고 하였다. 필요성 인식 율은 주민이 $83\%$, 환자보호자가 $79\%$, 환자가 $78\%$로서 세 집단 간에 유의한 차이 가 있었다. (P<.01). 인구학적 변수별로 보았을 때, 교육수준과 가정수입에 따라 인식 율에는 유의한 차이가 있어서 (P<.001, P<.01), 교육수준이 높을수록, 수입이 많을수록 높았다. 2. 필요성 인식 율은 가정간호사업 이용의사에 따라서도 유의한 차이가 있어서 (P<.001), 이용의사가 많은 군이 인식 율도 높았다. 3. 환자들의 필요성 인식 율은 퇴원시기에 대한 의견과 병원비 지출액에 따라 유의한 차이가 있어서 (P<.05, P<.02), 퇴원시기가 적절하다는 군이 부적절, 하다는 군보다, 또한 병원비 지출액이 적을수록 인식 율이 높았다. 진단명에 따라서는 피부 및 피하조직 진환$(100\%)$, 임신 및 출산에 관련된 합병증$(90\%)$, 신경 및 감각기계 질환$(85\%)$, 부상 및 중독$(83\%)$, 신생물$(79\%)$, 등에서 필요성 인식 율이 높았다. 4. 가정간호사업 이용에 대한 대상자의 의견을 $47.8\%$가 이용할 의사가 있었고, $49.9\%$는 상황에 따라 결정하겠다고 하였으며, $3.2\%$는 이용하지 않겠다고 응답하였다. 인구학적 변수별로 보았을 때, 연령별로는 노년층, 성별로는 남성이, 교육수준은 낮은 군이, 의료보험을 가진 군이 이용할 의사가 많았으며, 통계적으로 유의한 차이가 있었다. (P<.01, p<.001, p<01, p<.01). 5. 환자들의 가정간호사업 이용 의사는 퇴원시의 상태에 따라서 유의한 차이가 있어서 (P<.02), 상태 가 입원 시와 변화가 없거나 악화된 군이 이용할 의사가 많았다. 진단별로는 내분비계 질환$(63\%)$, 신생물$(57\%)$, 혈액 및 조혈기능 장애$(55\%)$, 부상 및 중독$(55\%)$, 등이 이용할 의사가 많았다. 6. 대상자들이 가정간호사업의 장점으로 생각하는 것은 환자의 심리적 안정$(66\%)$, 시간 절약$(57\%)$, 가족의 편이$(57\%)$, 환자 간호에 대해 배운다$(53\%)$, 질병 과정을 배운다$(51\%)$ 등이었다. 7. 대상자들이 가정간호사업의 단점으로 생각하는 것은 응급시에 대처하기가 어렵다$(49\%)$, 환자가 불안해 할 것이다$(41\%)$ 가정환경이 환장에게 부적합하다$(43\%)$ 등이었다. 8. 가정간호사업에서 수용할 수 있는 간호 업무로$50\%$ 이상의 대상자가 지정한 것은 활력징후측정, 경구 및 비경구 투약, 운동과 휴식지도, 개인 위생관리, 보건교육, 정신 심리 간호 등이었다. 9. 가정간호사업에 대한 지불방법은 $32.9\%$가 제공된 업무에 따라 지불해야 한다는 의견으로 가장 많았다.

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Behavior of the soil residues of the fungicide hexaconazole in a rice plants-grown microecosystem (pot) (살균제 hexaconazole 토양잔류물의 벼 재배 microecosystem(pot)중 행적)

  • Kyung, Kee-Sung;Lee, Byung-Moo;Lee, Jae-Koo
    • The Korean Journal of Pesticide Science
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    • v.8 no.3
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    • pp.198-209
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    • 2004
  • In order to elucidate the behavior of the fungicide hexaconazole in soil and rice plants, rice plants were grown for 42 days in a microecosystem (pot) containing fresh and 28 day-aged soil residues of $[^{14}C]$hexaconazole. The amount of $^{14}CO_2$ evolved during 28 days of aging was 0.11 % of total $^{14}C$-radioactivity treated and the averaged weekly degradation rate was 0.03%. Mineralization rates for 42 days of rice cultivation on fresh and aged paddy soils were 0.67% of the total $^{14}C$ in case of non-rice planting on aged soil and 1.17% in case of rice planting on aged soil, whereas 1.25% in non-rice planting on fresh soil and 1.72% in case of rice planting on fresh soil, suggesting that the amounts of $^{14}CO_2$ were evolved higher from fresh soils than aged ones and from rice-planting soils than non-planting ones. The amounts of volatiles collected were very low as background levels. Most of $^{14}C$-Radioactivity was remained in soil after 42 days of rice cultivation and $^{14}C$ absorbed through rice roots was distributed more in shoots than roots and translocated into the edge of shoots of rice plants. Amounts of non-extractable $^{14}C$ in soils were higher in rice planted soil than in non-planting soil. The distribution of non-extractable $^{14}C$ was increased in the order of humin>fulvic acid>humic acid. The amounts of $^{14}C$ translocated into rotational crop Chinese cabbage were 2.36 and 3.69% of the total $^{14}C$ in case of rice planted soil containing fresh and aged residues, respectively, suggesting that small amounts of $[^{14}C]$hexaconazole and its metabolite(s) were absorbed and their bound residues were more available than their fresh ones to Chinese cabbage.

The Effect of Portulaca oleracea on the Pathogens of Gastroenteritis in Infants (쇠비름 추출물이 신생아 장염 유발 미생물에 미치는 영향)

  • Bae, Ji-Hyun
    • The Korean Journal of Food And Nutrition
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    • v.25 no.2
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    • pp.233-238
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    • 2012
  • Diarrheal diseases constitute one of the major causes of morbidity and mortality in infants and young children globally. One of the main microorganisms causing diarrheal diseases is Campylobacter jejuni. For treatment of these diseases, Portulaca oleracea has been widely used as a folk remedy for a long time. This study was performed to investigate the antimicrobial activity of P. oleracea against gastroenteritis pathogens including C. jejuni. P. oleracea was extracted with petroleum ether, chloroform, ethylacetate, methanol, and hot water. The antimicrobial activity of the P. oleracea extracts was determined using the paper disc method, minimum inhibitory concentration, and the liquid culture method. The 10 $mg/m{\ell}$ ethylacetate extract showed the strongest antimicrobial activity against Salmonella typhimurium, Salmonella enteriditis, and Shigella spp.. The hot water extract from P. oleracea showed the highest anti-microbial activity against C. jejuni at 10~20 $mg/m{\ell}$. The hot water extract of P. oleracea retarded the growth of C. jejuni for 36 hr at $42^{\circ}C$.

Fossil Scaphopods from the Hagjeon Formation and the Duho Formation, the Cenozoic Pohang Basin, Korea (신생대 제3기 포항분지의 학전층과 두호층에서 산출된 굴족류 화석)

  • Kong, Dal Yong;Lee, Seong Joo
    • Korean Journal of Heritage: History & Science
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    • v.45 no.1
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    • pp.218-231
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    • 2012
  • A total of 126 fossil scaphopods (121 specimens from the Hagjeon Formation and 5 specimens from the Duho Formation) were found from the Cenozoic strata, Hagjeon and Duho Formations, Pohang Basin, Korea. Five species belonging two genera (Fissidentalium yokoyamai, F. sp. A, B, and Rhabdus sp. A, B) were classified: the most dominant species is Fissidentalium yokoyamai. The species of Fissidentalium yokoyamai is characterized by curved shell (accuration=3.90%) and very closely spaced longitudinal ribs on shell surfaces, while the species of Rhabdus is a nearly straight shell characterized by concentric growth lines without longitudinal ribs. Identification of two genera is somewhat easy due to such morphological differences but classification at generic level is hard because diagnostic features (e.g., cross section and apical structure) are lost in the most specimens. Consequently, except for Fissidentalium yokoyamai, the rest were classified temporarily as F. sp. A, B, and Rhabdus sp. A, B. Two types of preservation state were recognized: one is three-dimensionally preserved specimen (3D specimen) and the other is compressed specimen. Internal parts of the 3D specimen is filled with clastic sediments identical to the surrounding sediments of the shells, which is not observed in the compressed specimens. It is, thus, concluded that the 3D fossils were originally empty but internal cavity were immediately filled with the sediments, which may have protect from the compaction due to pressure during deposition of the gravelly to coarse sandstone of the Hagjeon Formation.

Cardiac Hemangioma of the Anterior Mitral Valve Leaflet - A case report - (승모판막 전엽에 발생한 심장혈관종 - 1예 보고 -)

  • Choi, Jae-Sung;Kim, Eung-Joong
    • Journal of Chest Surgery
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    • v.40 no.12
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    • pp.859-862
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    • 2007
  • A hemangioma at a cardiac valve leaflet is a rare finding. There are only five reported cases in the medical literature and no prior case reported in Korea. A previously healthy 45-year-old woman presented with an acute episode of numbness in the left side of the face and hand. Although no definite abnormalities were found on the neurological examination and testing the echocardiography revealed an echogenic mass in the anterior mitral valve leaflet. The tumor was excised en bloc from the leaflet and the defect was repaired with an autologous pericardial patch. Pathology examination confirmed the mass to be a hemangioma of the valve leaflet. Here we report this case and review the medical literature.

Primary Hemangiopericytoma of the Lung -1 Case Report - (폐에 발생한 원발성 혈관주위세포종 -1례 보고-)

  • 최광민;김건일;신호승;박희철;홍기우
    • Journal of Chest Surgery
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    • v.31 no.3
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    • pp.315-318
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    • 1998
  • Primary hemangioperiycytoma is quite rare tumor of the lung and arising from pericyte in external layer of capillaries. Most cases are developed in 4th and 5th decade, are asymptomatic, and have malignant otential. On chest radiography, primary pulmonary hemangiopericytoma shows lobulated, well demarcated, homogeneous soft tissue density. Microscopically, it consisits of numerous vascular spaces of variable size and shape separated by aggregates of tightly packed oval to spindle-shaped cells. Treatment of choice is surgical excision. We report a case of primary pulmonary hemangiopericytoma in a 16-year-old man who had well demarcated homogeneous mass in the superior segment of left lower lobe, but had no symptom. He had undergone left lower lobectomy. He has been followed up for 8 months but has no sign of relapse or metastasis yet.

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A Systematic Review of Clinical Trials on Alternative Medicine (대체의학의 임상실험 현황에 대한 체계적 고찰)

  • Cho, Hyun;Yoo, Jin-Yeong;Park, Soo-Hee
    • Proceedings of the KAIS Fall Conference
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    • 2010.11b
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    • pp.603-606
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    • 2010
  • 본 논문은 근거중심 대체의학의 현황과 범위를 알아보기 위한 것이다. 연구방법: 2000년부터 2010년 3월까지 Pubmed에 게재된 논문 중 alternative medicine으로 검색하여 체계적 고찰을 하였다. 2000년부터 2010년 현재까지 근거중심 대체의학에 대한 다양한 연구결과을 통합하기 위해 체계적 문헌고찰을 실시하였다. 682편의 연구 중 대체의학에 관한 임상연구는 19개였으며 연구전체 대상자는 2,573명이었다. 논문분석 결과 RCT(Randomized Controlled Trial) 실험 설계연구가 44%였으며 CCT(Controlled Clinical Trials)가 16%, OD(efficacy studies with either a controlled or an Other than controlled Design) 40%였다. 가장 많은 임상실험이 시행된 중재 방법은 Acupuncture과 Massage 였다. 대상 질병군 분포는 근골격계 및 결합조직의 질환과 관련된 '통증 완화'에 대한 임상연구가 20%, 다음으로 특정 감염성 및 기생충성 질환, 신생물이 각각 15% 순이었다. 근거중심 대체의학 현황을 파악하고자 체계적으로 고찰한 결과 대체의학을 통한 중재가 질병치료에 효과가 있는지에 대한 과학적 근거를 제시한 임상연구가 부족하다. 대체의학의 품질, 안정성, 유효성 확보를 위해 대체의학에 대한 질 높은 연구필요하며 근거중심 대체의학의 활성화가 필요할 것으로 생각된다.

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