• The Journal of Internal Korean Medicine
• /
• v.31 no.3
• /
• pp.600-611
• /
• 2010

Purpose : This study was to observe the nephroprotective effects of the traditional prescription, Opi-san(OPS). OPS has been generally used for treating various edematous renal diseases, including acute renal failure. Methods : Three different dosages of OPS extracts were administered once a day for 28 days (5 mg/kg, single intraperitoneally administered). On the 23rd day after OPS extract treatment, cisplatin was treated. All the rats (6 groups of 8 rats each) were checked as follows. Changes of body weight, kidney weight, serum BUN and creatinine levels were observed, as well as changes to the kidney MDA and GSH contents. The results were compared with captopril 100 mg/kg, of which the effects on cisplatin-induced acute renal failures were already confirmed. Results : Cisplatin-induced ARF were induced by oxidative stress and related lipid peroxidation in the present study. However, these ARF and inhibition of antioxidant effects induced by cisplatin were dose-dependently reduced by treatment of OPS extracts except in the 100 mg/kg treated group. The effects of OPS extracts at 500 mg/kg were similar to those of 100 mg/kg of captopril. Conclusion : This study suggests that OPS extracts 500 mg/kg showed favorable effects on the cisplatin-induced rat's ARF as similar to 100 mg/kg of captopril.

• Journal of Pharmacopuncture
• /
• v.14 no.4
• /
• pp.5-11
• /
• 2011

Objectives: The present study was undergone to determine whether Glycyrrhizae Radix pharmacopuncture intravenous injection exerts beneficial effect against the ischemia-induced acute renal failure in rabbits. Methods: Rabbits were treated with Glycyrrhizae Radix pharmacopuncture via i.v., followed by renal ischemia/reperfusion. The fractional excretion of glucose and phosphate were measured and the malondialdehyde content was also determined. The morphological changes of cortical part of kidney also observed with light microscope. Results: Renal ischemia/reperfusion caused increase of the fractional excretion of glucose and phosphate in ischemia-induced animals, which was prevented by Radix Glycyrrhizae extract treatment. Ischemia/reperfusion increased lipid peroxidation, which was prevented and morphological changes also altered by Radix Glycyrrhizae pharmacopuncture administration. Conclusions: These results indicate that lipid peroxidation plays a critical role in ischemia-induced acute renal failure and Glycyrrhizae Radix pharmacopuncture exerts the protective effect against acute renal failure induced by renal ischemia/reperfusion.

• Korean Journal of Psychosomatic Medicine
• /
• v.10 no.1
• /
• pp.55-60
• /
• 2002

Central pontine myelinolysis(CPM) and Extrapontine myelinolysis(EPM) are uncommon neurologic disorders associated with osmotic inequality between the extracellular fluid compartment and intracellular fluid compartment in the brain. Myelinolysis can occur in hyponatremia and after rapid correction of hyponatremia. It may be caused by various metabolic disturbances such as chronic alcoholism, malnourishment, cancer, chronic renal failure and organ transplantation. The authors reported a 43-year-old male patient who have received a kidney transplantation because of chronic renal failure due to diabetic nephropathy. The patient manifested psychotic symptoms such as delusion, loosened association, hallucination, inappropriate affect and aggressiveness as a sequele of CPM and EPM. He also showed neurocognitive impairment such as disorientation, memory impairment, decresed intelligence and aphasia. These manifestations are rare in CPM and EPM. We discuss the clinical features, diagnosis, course and management of the patient which may be clinically significant in the neuropsychiatric aspect especially at the consultation-liaison field.

• Journal of Nutrition and Health
• /
• v.34 no.4
• /
• pp.359-366
• /
• 2001

Studies were carried out to explore the influence of dietary protein level on bone metabolism in uninephrectomized rat (experimental renal failure model) when dietary Ca and P contents were equal. Male rats were uninephrectomized or sham operated and fed 8%, 15% and 40% casein diets for 24 weeks. Ca and P contents of the all diet were 0.4% and 0.6% respectively. The results are summarized as follows. We did not found any significant difference in PTH and Ca level of the serum, Ca intake and Ca excretion among the experimental groups. There was significant positive correlation between the PTH and phosphate level. There was significant inverse correlation between serum Ca and creatinine level. The effect of the dietary protein level and renal mass loss on density and Ca contents of the bone were small and different according to the kinds of the bone. Low protein diet was associated with a significant enhancement of scapular density. Femur and vertebra density, however, were not influenced by dietary protein level and uninephrectomy. Light microscopic examination showed several calcified foci in the kidney in all experimental groups. Low protein diets have been used for a long time in the conservative management of chronic renal failure as they have a beneficial effect in preventing the appearance of symptoms. This study elucidated that part of beneficial effects of the low protein diet related to the suppression of the hyperphosphatemia. And these results, even though uninephrectomized rats fed high protein diet, the secondary hyperparathyroidism is supressed by the regulation of the P level. Therefore this study emphasized the need to pay more attention to the regulation of dietary P level as well as dietary protein content in chronic renal failure. (Korean J Nutrition 34(4): 359∼366, 2001)

• Journal of Korean Library and Information Science Society
• /
• v.48 no.4
• /
• pp.77-105
• /
• 2017

As our society enters an aged society, it is becoming increasingly important to resolve digital divide of older adults. However, the digital divide of the older adults are generally neglected compared to other information poor. The aim of this study is to propose considerations for library policy development in order to resolve the digital divide of the older adults. The study examined regulation of the Framework Act on National Informatization and the Ministry of Science and ICT, the Ministry of Culture, Sports and Tourism, the Ministry of Health and Welfare, the Ministry of Employment and Labor. Also it investigated guidelines and current status of services to older adults in the library. The study suggested that public libraries should be used as a basic base for the services to resolve the digital divide to older adults across the country, and the services should be organized systematically and sustainably through public libraries.

• Journal of Advanced Navigation Technology
• /
• v.19 no.3
• /
• pp.237-243
• /
• 2015

This paper presented the design of wireless power transfer (WPT) system using electromagnetic induction techniques and analysed WPT efficiency. Also, we presented the optimum coil condition by measuring the efficiency variation according to some receiving coil parameter changes. Voltage change is measured by receiving coil position for the designed transmitting and receiving circuit. Voltage change according to inductance variation at the same position and charging time are compared at the same environment by using a developed application program to realize an optimum WPT system. Developed wireless power transfer system using electromagnetic induction techniques uses 125 kHz. It takes 16 minutes by using wired charger, and 23 minutes by using wireless charger for charging from 50% to 60% charging status.

• The Journal of Korean Oriental Chronic Disease
• /
• v.10 no.1
• /
• pp.46-52
• /
• 2005

When we prescribed Shiryungtang to a 65 years-old male patient with ARF after stroke, we could observe that his symptoms, I/O balance and laboratory findings were all improved. Therefore, we suggest that shiryungtang might be useful for ARF in the patient with stroke.

• Proceedings of the Korea Contents Association Conference
• /
• 2009.05a
• /
• pp.1026-1030
• /
• 2009

Western wedding ceremony is generalized and it has been focused on bride's wedding dress and jewelry design as coming in western culture in Korea. Especially, metal design has developed a lot as enlarging the scale of jewelry market but study of gem cutting design is insufficient really. To meet demands of consumers of the 21th century we try fancy not standardizing style gems by using new faceting technique to maximize brilliance as wedding jewelry. In this thesis, we use popular and moderate priced synthetic cubic zirconia(CZ) which is able to alternate expensive diamond and natural gems to make easy approach of consumer as main gem material of wedding jewelry. And we develop various gem cutting design that is used synthetic cubic zirconia(CZ). We will contribute to development of new wedding jewelry design proposing various gems cutting style fitted for gem setting technique of wedding jewelry.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.4
• /
• pp.265-275
• /
• 2018

This study is a qualitative investigation that used Colaizzi's (1978) phenomenological method to evaluate the meaning and nature of the experience of dialysis of eight long-term (>30 years) hemodialysis patients with chronic renal failure. Data were collected from February 27, 2017 to May 30, 2017 by in-depth interviews. Respondents were then divided into three categories, 'entirely different life', 'getting back up again' and 'focusing on survival' with nine theme clusters and 22 themes. In general, patients initially experienced an entirely different life and overcame a difficult situation when beginning dialysis, then came to know methods for self-care, shared the experience of dialysis, and focused on survival while receiving dialysis over the long-term. Development of variety of education methods depending on long-term experience of dialysis and nursing care intervention to enable chronic patients to adapt to dialysis and continue their own self-management is necessary.

• Polymer(Korea)
• /
• v.34 no.5
• /
• pp.485-489
• /
• 2010

Poly(lactic acid)(PLA) has been modified by electron radiation in the presence of 5 phr glycidyl methacrylate (GMA) to enhance the melt strength of PLA. The modified PLA was prepared by varying the dose of irradiation and was characterized by observing the thermal properties, the melt viscoelastic properties and the gel fraction. The irradiated PLA with 300 kGy in the presence of 5 phr GMA showed drastically improved complex viscosity and storage modulus properties: a complex viscosity of about 210 times higher and a storage modulus of 14500 times higher than those of virgin PLA when measured at a frequency of 0.1 rad/s. Gel fraction study revealed that a branching reaction was more dominant than a crosslinking reaction when the PLA was irradiated with less than 200 kGy.