• The Science & Technology
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• v.5 no.2 s.34
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• pp.10-11
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• 1972

이 농약은 kist의 농약합성실장 오 동영 박사가 연구 발표한 것으로 '71년 발명의 날 대통령상을 받은 바 있으며, 일부 농약회사에서 기업화를 검토중에 있다. -편집부 주-

• Agrochemical news magazine
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• v.20 no.1 s.148
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• pp.60-63
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• 1999

미국에서 농약을 판매하기 위해서는 먼저 해당농약을 등록하여야 하는데 등록업무는 연방 살충$\cdot$살균$\cdot$살서제법(FIFRA : Federal Insecticide, Fungicide and Rodenticide Act)에 의거, USDA(미농무성)에서 관장했으나 1970년 12월 이후부터 신설된 EPA(환경보호청)가 맡고 있다. 여기에 소개하는 내용은 Farm Chemicals Handbook 최근호(''98)의 부록(regulatory file)에 수록된 미국농약관리법중이 주요 내용이며 우리나라의 농약안전관리와 신농약개발 업무에 직$\cdot$간접으로 관계되는 모든 분들에게 참고가 되었으면 하는 바람으로 호에 걸쳐 소개한다.

• Proceedings of the Korean Society of Life Science Conference
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• 2001.02a
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• pp.70-70
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• 2001

• The Korean Journal of Pesticide Science
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• v.10 no.2
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• pp.69-75
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• 2006

For the development of new agrochemical fungicide 3-amino-2-phenylimino-1,3-thiazolines 2 were designed through the molecular modification based on isostere concept of 3-methyl-2-phenylimino-1,3-thiazolines 1 which showed antifungal activity against rice blast. All the compounds 2 were fit Lipinski rule and they had higher solubility in water than that of 1 by virtual calculation. We constructed 195 kinds of focused library of 3-amino-2-phenylimino-1,3-thiazolines through 6H-[1,3,4]thiadiazines (195 compounds) which synthesized from the reaction of thiourea 4 with $\gamma$-chloroacetoacetanilides 5.

• The Korean Journal of Pesticide Science
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• v.9 no.1
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• pp.41-50
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• 2005

For the removal of residual pesticides in ginseng extracts, we estabilished the removal process using pilot plant system, the characteristic components of ginseng maintains only. According to the agricultural chemical removal process, we monitored residual pesticides of 155 species, compraing the characteristic components of ginseng. The process of 4 types of agricultural chemical removal process compared to the control test was appeared that the residual pesticides were eliminated. As results above, the most efficient method of the possibility of raising the removal ratio of the agricultural chemical construction process was dried process of hexane after dipping and also remaining quality of the hexane appeared lowly. Besides, the removal process had an effected on the ginsenocide os ginseng, only the residual pesticides will be able to remove.

• The Korean Journal of Pesticide Science
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• v.7 no.2
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• pp.117-122
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• 2003

Modeling and synthesis of novel hydroxyethyl 2-iminothiazolines were carried out through molecular modification of lead compound, 2-phenyliminothiazolines 1, for the purpose of development of new fungicidal agrochemicals. Oxygen atom of the hydroxyethyl group in 2-iminothiazolines 3 would locate in the proximity of the imino carbon at C-2 of 2-iminothiazoline moiety through neighboring group participation, and so that it would affect the biological activity of the molecule. Reaction of $\gamma$-chloroacetoacetanilides 5 with hydroxyethylureas 6 gave 29 kinds of new corresponding hydroxyethyl 2-iminothiazolines 3 in high yields.

• The Korean Journal of Pesticide Science
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• v.9 no.2
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• pp.122-131
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• 2005

For development of new agrochemical fungicide, syntheses of pyrrolo[2,1-b]thiazole carboxanilide derivatives 9 and antifungal screening against 6 kinds of plant pathogens were carried out. Functionalization of carboxylic acid on C-2 into carboxanilide in the pyrrolo[2,1-b]thiazole resulted in new 20 candidates, in which are ${\alpha},{\beta}$-unsaturated carboxanilide and methyl groups that are in cis relationship. Treatment of acetoxy-1,4-thiazin with magnesium in refluxing methanol gave pyrrolo[2,1-b]thiazole ethyl ester 4 in higher yield than that of the previous report. Hydrolysis of this compound afforded the corresponding acid 5, which reacted with aniline derivatives in the presence of coupling reagent, DIC to give pyrrolo[2,1-b]thiazole carboxanilides 9. As the result of in vivo antifungal assay of 9 against rice blast, rice sheath blight, cucumber gray mold, tomato late blight, wheat leaf rust, and barley powdery mildew, some compounds showed selectively antifungal activities against the rice blast and wheat leaf rust.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.61-69
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• 2020

This paper examined the operational efficiency of the new rice variety "Sindongjin" farmed by the Rural Development Administration. Thirty farmers were surveyed in the survey area--Jeonbuk-do Province. The operational efficiency was analyzed by studying the data of these 30 farmers. The operational efficiency of the farmers was analyzed through a survey using the DEA model for analysis. DEA analysis was performed to obtain the technical efficiency of the farmers. The results showed that the DEA technical efficiencies of 12 farmers were efficient, and 18 farmers were inefficient. Farmers No. 13 and No. 25 were representative of inefficiency, and the results show that the cost of input elements was high. An analysis of the determinants of efficiency through the Tobit model found that the operating efficiency increased with decreasing variable costs (Seed costs, By-product fertilizer costs, General fertilizer cost, Pesticides cost, Cost of water, electricity, gas, and Cost of small farm implements) and fixed costs (Repair cost and Other costs). There is a problem of excess input from farmers, and these input costs need to be reduced.

• The Korean Journal of Pesticide Science
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• v.7 no.1
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• pp.51-57
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• 2003

For the purpose of a development of new agrochemical fungicides, new compound 4 in which 1,3-thiazoline scaffold as well as urea moiety in the structure was designed through molecular modification of lead compound, 2-imino-1,3-thiazone based on isosterism. The reaction of N-alkylthiourea 5 and bromoacetonitrile in ethanol gave 2,4-diimino-1,3-thiazolidine hydrobromide 6 regioselectively, which was treated with isocyanates gave the corresponding 8 which is tautomer of 4. Antifungal screening (in vivo) of the synthesized compound 8 against typical plant diseases, which include rice blast, rice sheath blight, cucumber gray mold, tomato late blight, wheat leaf rust, and barley powdery mildew, was carried out. Antifungal activities against rice blast of the compound 8 were weaker than those of 2-phenylimino-1,3-thiazoline 1. Some compounds showed weak antifungal activities against wheat leaf rust.

• The Korean Journal of Pesticide Science
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• v.2 no.1
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• pp.24-31
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• 1998

Chemical derivative synthesis of ricinine, an active compound of Ricinus communis which showed high mortality against brown planthopper (Nilaparvata lugens), was performed to improve its pesticidal activity and the toxicity of 12 synthetic derivatives against major insect pests and phytopathogenic fungi were examined. Carbamate derivatives of ricinine could be synthesized from the precursor of ricinine, chloronorricinine and norricinine, whereas the derivatives were not synthesized from chlororicinic acid and ricinic acid having ketone group of pyridine ring. In organophosphates, reaction with oxon type of phosphate gave better yield than thiono type. Among the organophosphate derivatives of ricinine, thiono type of derivative structure gave $96.3%{\sim}100%$ mortality of the brown planthopper and the two-spotted spider mite (Tetranychus urticae) at 500 ${\mu}g/ml$ level. On the other hand, carbamate derivatives did not show insecticidal activity. In the fungicidal activity of ricinine derivatives, the derivative having amino radical at the 2 position of ricinine gave 85 to 100% of mycelium growth inhibition effect against ten major plant pathogens at the 200 ${\mu}g/ml$ level. In particular, the control value of the derivative on the rice blast (Pyricularia grisea) and barley powdery mildew (Erysiphe graminis) at the 250 ${\mu}g/ml$ level in vivo under greenhouse conditions was 92% and 96%, respectively.