• The Monthly Diabetes
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• s.34
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• pp.74-75
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• 1992

• Journal of the korean veterinary medical association
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• v.24 no.1
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• pp.13-15
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• 1988

• TTA REPORT
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• v.5 no.3 s.19
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• pp.64-67
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• 1993

• 기계와재료
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• v.5 no.2 s.16
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• pp.17-25
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• 1993

• KDI북한경제리뷰
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• v.23 no.12
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• pp.65-68
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• 2021

• The Korean Journal of Pharmacology
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• v.25 no.1
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• pp.23-30
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• 1989

Buprenorphine, one of the mixed agonist-antagonist opioid drugs was used to inverstigate the opioid receptor on frog sciatic nerve A fibers. Action potentials were recorded for 4 hrs by a sucrose gap apparatus which were separated by four rubber membranes. To examine the one of the mechanism of action of buprenorphine, meperidine or naloxone was added after or before the treatment of buprenorphine. The results of this experiment were as follows: 1. Buprenorphine suppressed significantly the compound action potentials of frog sciatic nerve, and the maximal effects were shown both at $10^{-4}\;M$ and at $10^{-8}\;M$. 2. The dose-response relationship of buprenorphine on the depressant effect in frog sciatic nerve was biphasic and inverted U-shaped. 3. Buprenorphine blocked the effect of Meperidine $(10^{-3}\;M)$ on this preparation. 4. The depressant effcct of Buprenorphine on frog sciatic nerve was blocked by $10^{-8}\;M$ naloxone. From the above results, buprenorphine acts as one of agoinist-antagonistic effect on frog sciatic nerve, and the opioid receptor on this preparation is located on or near the intracellular opening of the sodium channels, which are sensitive to naloxone.

• Progress in Medical Physics
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• v.9 no.2
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• pp.95-104
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• 1998

The dynamic properties of the 3rd-order neuron of the retina was investigated by using conventional intracellular recording techniques. Experiments were performed in the superfused retina-eyecup preparation of the channel catfish, Ictalurus punctatus. The cornea, iris, lens, and vitreous were removed by absorption with Kimwipe tissue under the dissection microscope thereby exposing the retina in a hemi -eyecup. The electrical signal was amplified by electrometer, viewed on oscilloscope. Regular signals from the cells were recorded on a penwriter and stored by data recorder and computer. Full-field, spot or annular light stimuli were generated on a computer monitor and focused onto the retina. Baclofen hyperpolarized the dark membrane potential, suppressed sustained component and enhanced transient component of the ON-sustained cell with a large transient component, but did not affect the surround antagonism of the cell. Baclofen selectively suppressed responses evoked by moving bar light stimuli on the ON-OFF transient cell. The results suggest that transient cells have directional selectivity in the inner retina. These dynamic properties of amacrine and ganglion cells were modulated by baclofen. Therefore, it is presumed that there is baclofen-induced directional selectivity in ON-OFF transient cells in the catfish retina.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.4
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• pp.317-326
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• 2020

Deep blocking of consciousness alone does not prevent a reaction to severe stimuli, and copious amounts of pain medication do not guarantee unconsciousness. Therefore, anesthesia must satisfy both: the loss of consciousness as well as muscle relaxation. Muscle relaxants improve the intra-bronchial intubation, surgical field of vision, and operating conditions, while simultaneously reducing the dose of inhalation or intravenous anesthesia. Muscle relaxants are also very important for breathing management during controlled mechanical ventilation during surgery. Excessive dosage of such muscle relaxants may therefore affect neurological examinations during surgery, but an insufficient dosage will result in movement of the patient during the procedure. Hence, muscle relaxation anesthesia depth and neurophysiological monitoring during surgery are closely related. Using excessive muscle relaxants is disadvantageous, since neurophysiological examinations during surgery could be hindered, and eliminating the effects of complete muscle relaxation after surgery is challenging. In the operation of neurophysiological monitoring during the operation, the anesthesiologist administers muscle relaxant based on what standard, it is hoped that the examination will be performed more smoothly by examining the trends in the world as well as domestic and global trends in maintaining muscle relaxant.

• Digital Contents
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• no.10 s.161
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• pp.50-53
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• 2006

21세기 '신경제' 시스템에서 흔히 지식은 '미래 경제의 석유'로 비유된다. 그만큼 경제를 추진하는 역량이 크다는 말이다. 대체로 데이터가 수치화된 자료, 즉 조각난 정보라면 그것이 모인것이 '정보', 이후 쓰임새를 갖춘 통합된 정보가 '지식'으로 분류된다. 그런데 이 지식을 창출하고 저장하는 방식은 컴퓨터ㆍ위성ㆍ휴대전화ㆍ인터넷, 기타 디지털 기술의 확산으로 급격하게 변하고 있다. 또 아울러 지식이 쇠퇴하는 속도도 빨라져서 엘빈 토플러의 용어대로 수많은 지식들이 금방 '무용지식(obsoledge)'으로 전락하고 만다.

• Digital Contents
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• no.4 s.119
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• pp.30-32
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• 2003

GDC(Game Developer Conference)2003 (이하 GDC)은 Make Better Game 이라는 모토로 지난 3월 5일부터 8일 까지 미국 신경제 중심지 산호세에서 개최됐다. GDC는 세계 게임 기술 동향 및 시장 전망을 조망하는 국제 콘퍼런스로 E3, 도쿄게임쇼, ECTS 등이 게임 퍼블리셔와 비즈니스 중심인 반면 GDC는 게임개발에서 체험한 게임 노하우를 상호 교환하는 '게임개발자 중심'의 컨퍼런스가 모태가 되었다는 점에서 여타 컨퍼런스와 다른 특징이 있다.