• 제목/요약/키워드: 신경정신학

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혈관성 치매의 약침 치료에 대한 중의학 임상연구 동향 (A Review on the Trend of Clinical Research on Pharmacopuncture for Vascular Dementia in Traditional Chinese Medicine)

  • 홍민호;김만기;구병수;김근우
    • 동의신경정신과학회지
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    • 제31권4호
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    • pp.315-327
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    • 2020
  • Objectives: The aim of this study was to review the research trends in the treatment of pharmacopuncture for vascular dementia in Traditional Chinese medicine. Methods: We searched for articles in the China National Knowledge Infrastructure (CNKI) database from January 2000 to August 2020. Results: Among the total 63 articles, 9 articles were selected. All studies were randomized controlled trial studies. The Diagnostic and Statistical Manual of Mental Disorders (DSM) was most frequently used as diagnostic criteria. Effective rate and Activity of Daily Living (ADL) were most commonly used as outcome measurements. Angelica gigantis Radix (當歸), Salvia miltiorrhiza Bunge (丹蔘), and Astragali Radix (黃芪) were the most commonly used ingredients in pharmacopuncture. Joksamni (ST36) and Sinsu (BL23) were the most commonly used acupoints for pharmacopuncture treatment. Based on the Risk of Bias (RoB) of these 9 articles, the overall quality of studies was low. Conclusions: Pharmacopuncture could be considered for the treatment of vascular dementia. In the future, various systematic studies on dementia are needed.

신경발달학적 신경영상학 (NEUROIMAGING IN NEURODEVELOPMENT)

  • 이정섭
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제16권1호
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    • pp.26-32
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    • 2005
  • 신경발달학적 신경영상학은 급속하게 발전하는 분야이고 사용되는 새로운 영상학적인 기술의 수도 해마다 급속하게 증가하고 있다. 신경발달학적인 관점에서 소아청소년 정신과적 장애들에서 아직 명확한 신경병리학적인 원인은 밝혀지지 않았으나, 점차로 많은 수의 논문에서 일관적인 뇌영상학적인 이상 소견들이 발표되고 있다. 이 논문에서는 신경발달학적인 관점에서 신경영상학적인 연구에서 과거와 현재 상황을 기술하고 제한점과 함께 미래에 대한 조망을 하고자 한다.

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불안에 대한 태극권 치료의 해외 임상연구 동향 (A Review on Clinical Research Trends in the Treatment of Tai Chi on Anxiety)

  • 김주영;홍민호;구병수;김근우
    • 동의신경정신과학회지
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    • 제30권3호
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    • pp.275-285
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    • 2019
  • Objectives: This study was performed to review the research trends in the treatment of Tai Chi on anxiety. Methods: We searched for articles in Pubmed and China National Knowledge Infrastructure (CNKI) from January 2009 to December 2018. The selected studies were evaluated by Jadad Scale. Results: One pre-post comparison study and seven controlled clinical trials were selected. HAMA (Hamilton Rating Scale for Anxiety) and STAI (State Anxiety Inventory) were the most frequently used diagnostic criteria. For outcome measurement, STAI was again the most commo. From Jadad Quality Assessment Scale of 8 articles, the overall quality of the studies was low. Conclusions: According to this study, it seemed that Tai Chi treatment on anxiety disorder is an effective and safe intervention. Therefore, based on this study, more clinical research on diverse forms of treatments of anxiety disorder should be performed in Korean medicine in the near future.

군발 두통 환자의 한방 치료 치험 1례: 증례 보고 (Korean Medicine Treatment for a Patient with Cluster Headache: A Case Report)

  • 김만기;조한별;김근우;구병수
    • 동의신경정신과학회지
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    • 제33권2호
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    • pp.215-225
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    • 2022
  • Objectives: The purpose of this study was to report the effect of Korean medicine (KM) treatment on a patient diagnosed with cluster headache. Methods: The patient included in this study was diagnosed with cluster headache who received KM therapy (herbal medicine, acupuncture, moxibustion, cupping, and chu-na treatment). The main symptom of the patient was pain in the left occipital region and orbital region. It was diagnosed as a pattern of liver depression and spleen deficiency by oriental medicine. During the hospitalization period, treatment effect was evaluated by NRS. HIT-6. BDI, and STAI were additionally performed to assess depression and anxiety. Results: After 24 days of treatment, the intensity of headache decreased from NRS7 to NRS3. During follow-up at two weeks, there was no pain. Normal daily activities were possible. Conclusions: Korean medical approach might be useful for pain relief and restoration of daily living ability for patients with cluster headache.

정신의학, 이대로 좋은가?-신경과학 시대에서 정신의학의 영역 확대 방안 (Psychiatry, Is It Now Okay? - Enlarging the Boundary of Psychiatry in the Neuroscience Era)

  • 박종한;김남수
    • 생물정신의학
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    • 제8권1호
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    • pp.53-61
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    • 2001
  • 현재 국내 신경정신의학계가 당면하고 있는 학문과 진료 영역의 문제점들과 그 원인들을 살펴보고 정신과 의사들의 학문적인 성숙과 진료 영역의 확대를 위한 해결 방안을 모색해 보았다. 진료 영역이 축소된 이유로 의료계 내부에서는 최근에 이루어진 신경과학의 눈부신 발전, 신경정신과에서 신경과와 정신과로의 분리, 의료 제도의 변화, 정신과 의사들의 안이한 대처, 정신의학 교육의 왜곡 등을 생각할 수 있다. 의료계 외부의 조건들로는 정신의학과 정신과에 대한 사회적 편견, 의료에 대한 외부의 규제를 들 수 있다. 정신의학의 영역을 확대하기 위해서는 의과대학생 교육, 전공의 수련 과정, 전문의 연수 교육, 정신의학 교과서의 편찬 등을 통한 정신의학 교육의 개편 강화, 신경정신의학의 정체성 재확립, 그리고 신경과학과 신경학 교육의 강화 등을 적극적으로 추진해야 할 것이다. 아울러 정신과 의사들의 활동 분야를 확대하고 행동과학을 임상 진료 과목으로 개발하며 정신의학과 유관한 제 3 의 전문 진료 과목을 창출하고 정신과 의사의 기본적인 술기에 일차 진료 의사의 역할을 추가하는 방안들도 고려해 볼 필요가 있다.

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SH-SY5Y 세포에서 도네페질과 병용투여시 신경보호 효과를 나타내는 한약재의 in vitro 선별 연구 (In Vitro Screening of Traditional Medicinal Herbs Combined with Donepezil for Neuroprotective Effects in SH-SY5Y Cells)

  • 송수진;류천봉;홍민호;김근우;구병수
    • 동의신경정신과학회지
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    • 제30권3호
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    • pp.199-207
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    • 2019
  • Objectives: The purpose of this study was to evaluate the neuroprotective effects of donepezil and 33 kinds of herbal extract combinations in SH-SY5Y cells with $A{\beta}_{25-35}$ treatment. Methods: MTT assay was performed to measure the cell viability of each herbal extract combined with donepezil against $A{\beta}$-induced neurotoxicity. The most active extracts were then subjected to assess the effects on CREB phosphorylation and COX-2 expressions through the western blot analysis. Results: There were eight herbal extracts representing significant increase on the cell viability: 1) Erycibe obtusifolia, 2) Polygonum multiflorum, 3) Polygala tenuifolia, 4) Illicium verum, 5) Santalum album, 6) Loranthus parasticus, 7) Platycladus orientalis, and 8) Zanthoxylum piperitum. Especially, when Santalum album and donepezil were treated together, the phosphorylation of CREB significantly increased and COX-2 protein expression was significantly inhibited. Conclusions: Among the screened herbal extracts, combination treatment of each of the eight herbs and donepezil showed neuroprotective effects in SH-SY5Y cells. Additionally, the combination of Santalum album and donepezil suggested cognitive improvement by up-regulation of p-CREB and down-regulation of COX-2.

조현병의 침 치료에 대한 중의학 임상연구 동향 (A Review on Clinical Research Trends in the Treatment of Acupuncture on Schizophrenia in Traditional Chinese Medicine)

  • 홍민호;송수진;김주영;구병수;김근우
    • 동의신경정신과학회지
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    • 제29권4호
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    • pp.281-290
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    • 2018
  • Objectives: The objective of this study was to review the research trends in the treatment of acupuncture on schizophrenia in traditional Chinese medicine. Methods: Articles in the China National Knowledge Infrastructure (CNKI) from September 2008 to August 2018 were reviewed. The selected articles were evaluated by the Jadad Scale. Results: 11 articles were selected from a total of 33 articles. 1 study was single group before-and-after study while the other 10 studies were randomized controlled trial studies. Chinese Classification of Mental Disorders-3 was most frequently used as a diagnostic criterion. Brief Psychiatric Rating Scale was most commonly used as an outcome measurement. From Jadad Quality Assessment Scale of the 11 articles, the quality of the studies generally was low. Conclusions: BaekHoi (GV20) and YinDang (EX-HN3) are most commonly used in acupuncture treatment. According to this study, acupuncture treatment in addition to western medication on schizophrenia is more effective as compared to the controls. In future, this study could be primary data for development of more clinical research on the treatment of schizophrenia in Korean medicine.

의사-환자의 치료적 관계에 대한 질적 사례연구 (A Qualitative Case Study of the Medical Doctor-Patient Therapeutic Relationship)

  • 강성현;이도은;최정현;김광우;유영수;강형원;정문주
    • 동의신경정신과학회지
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    • 제34권3호
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    • pp.319-334
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    • 2023
  • Objectives: The purpose of this study was to identify the doctor-patient relationship perceived by doctors in clinical settings and the effect of doctor-patient relationships on treatment schemes. A qualitative case study was conducted for this purpose. Methods: In-depth interviews were conducted with five oriental medicine doctors and doctors working in clinical settings using a semi-structured questionnaire. Transcription and coding were performed to analyze the data. By analyzing each case individually through within-case analysis, we attempted to find themes that emerged from the research subjects' experiences with establishing relationships with patients. Afterward, a cross-case analysis was conducted to identify the meaning of the experiences through commonalities and differences. Results: Within-case analysis confirmed the thoughts and emotions of the research participants in recognizing, defining, and participating in doctor-patient relationships while delivering treatments. Case-to-case analysis derived two themes, seven categories, and 20 meaningful units for doctor-patient relationships. Conclusions: The study found that a doctor-patient relationship regarding patient treatment could be established based on the doctor's 'professional qualifications' and 'human qualities'. In the future, it is necessary to present an educational model for relationship-based intervention techniques and personality maturity. Follow-up research should be conducted to enable the establishment of therapeutic relationships between doctors and patients.

신경정신학에 융복합되는 신경생물학적 접근법의 한계점: 발달성 협응장애와 두 시각 이론에 관한 종설 (Limitations of neurobiological approach convergent to neuropsychiatry: DCD and two visual systems theory)

  • 이영림
    • 디지털융복합연구
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    • 제13권6호
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    • pp.225-234
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    • 2015
  • 신경생물학 접근법은 정신학에서의 심신 이원론 문제를 해결하고 새로운 진단과 치료법을 발달시키는 데 도움을 주었다. 하지만 신경정신장애의 복합성 때문에 신경생물학의 신경해부학 부분을 너무 강조하는 것은 문제가 될 수 있다. 예를 들어, 발달성 협응장애 (DCD)는 일반적으로 움직임과 관련된 장애이지만 종종 지각과도 긴밀한 관계가 있다. 뇌의 기능적 분류에 입각한 두 시각 이론은 대뇌의 복측은 물체의 재인을, 배측은 움직임, 위치와 관련되어 있다고 주장한다. 하지만 물체의 지각은 시각적으로 유도되는 행동과 밀접한 관련이 있다. 이 논문에서는 두 시각 이론을 설명하는 기본적인 연구들을 검토하고, 이 이론에 대한 비판을 제시한다. 특히, 발달성 협응장애와 같은 운동뿐만 아니라 지각과 관련이 있는 신경정신장애에 구조적인 신경생물학 접근법을 적용하는 것의 한계점을 제시한다. 결론적으로, 현대의 신경정신분야에 융복합적으로 사용되는 신경생물학 접근법은 유용하지만, 신경구조적 분류에 너무 집중하면 한계점이 나타날 수 있다.