• Title/Summary/Keyword: 시험적 연구

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Analysis of Exploratory Thoracotomy in Non-Small Cell Lung Cancer (원발성 폐암에서의 시험적 개흉술의 분석)

  • 허재학;성숙환;김영태
    • Journal of Chest Surgery
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    • v.32 no.6
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    • pp.536-542
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    • 1999
  • Background: The purpose of this study is to improve the quality of the diagnostic procedures in the preoperative evaluation so as to reduce the unnecessary thoracotomy and to ensure resectability in non-small cell lung cancer. Material and Method: Of 616 patients who underwent thoracotomy for primary lung cancer from January 1990 to December 1996, 59 patients(9.6%) turned out to have inoperable lesions after the thoracotomy. We reprospectively reviewed the bronchoscopic findings, methods of tissue diagnosis, CT scans, pulmonary function test and lung perfusion scan, reasons for nonresectability, and adjuvant therapy, and then followed up on the survival rate after exploratory thoracotomy. Result: The cell types were squamous cell carcinoma in 38, adenocarcinoma in 15, large cell carcinoma in 3 and others in 3. Primary loci were RUL in 20, RML in 6, RLL in 8, LUL in 13, LLL in 4 and others in 8. The reasons for non-resectability were various; direct tumor invaison to mediastinal structures(n=41), seeding on pleural cavity(n=8), poor pulmonary function(n=2), invasions to extranodal mediastinal lymph node(n=2), technical non- resectability due to extensive chest wall invasion (n=3), small cell carcinoma (n=1), malignant lymphoma(n=1), and multiple rib metastases(n=1). In the follow-up of 58 patients, 1-year survival rate was 55.2% and 2-year survival rate was 17.2% and the mean survival time was 14 months. When compared according to cell types or postoperative adjuvant therapeutic modalities, no significant difference in the survival rates were found. The squamous cell carcinoma was frequently accompanied by local extension to contiguous structures and was the main cause of non-resectability. In adenocarcinoma, pleural seeding with malignant effusion was frequently encountered, and was the major reason for non-resectability. Conclusion: These data revealed that if appropriate preoperative diagnostic tools had been available, many unnecessary thoracotomies could have been avoided. Both the use of thoracoscopy in selected cases of adenocarcinoma and the more aggressive surgical approach to the locally advanced tumor could reduce the incidence of unnecessary thoracotomies for non-small cell lung cancers.

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Analytical and Experimental Studies on the Natural Frequency of a Composite Train Carbody (복합재 철도차량 차체 고유진동수에 대한 해석 및 시험적 연구)

  • Jeong Jong-Cheol;Cho Sea-Hyun;Seo Seong-Il;Kim Jung-Seok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.4 s.247
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    • pp.473-480
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    • 2006
  • This paper explains analytical and experimental studies to evaluate the natural frequency of a composite carbody of Korean tilting train. The composite carbody with length of 23m was manufactured as a sandwich structure composed of 40mm-thick aluminium honeycomb core and 5mm-thick woven fabric carbon/epoxy face. From the finite element analysis, the 1st bending and 1st twisting natural frequency of the composite carbody were 11.67Hz and 14.4Hz, respectively. In order to verify the analytical results, the natural frequency measuring tests were performed. The measured 1st bending and twisting natural frequencies of the composite carbody were 10.25Hz and 11.0Hz, respectively. Both of these results satisfied the design requirement.

A Role of Trial Radiation Therapy in the Pineal Region Tumors (송과체부 종양에서 시험적 방사선치료의 역할)

  • Kim, Yeon-Shil;Ryu, Mi-Ryung;Chung, Su-Mi;Kim, Moon-Chan;Yoon, Sei-Chul
    • Radiation Oncology Journal
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    • v.20 no.2
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    • pp.100-107
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    • 2002
  • Purpose : The aim of this retrospective study was to assess the treatment results of 30 patients with pineal region tumors who were underwent radiation therapy under the diagnosis by either CT or MRI. There was no histological verification. We analyzed the prognostic factors that have a significant effect on the overall survival (OS) and disease free survival (DFS) rates. Materials and Methods : A total 30 patients with pineal region tumors were treated between March 1983 and August 1995. After a trial radiation therapy of $20\~30\;Gy/2\~3$ weeks, the patients were evaluated for their clinical response and radiological response by either CT or MRI and the final treatment direction was then decided. According to their response to the trial radiation therapy and the involved site, radiation treatment was given in various fields i.e., local, ventricle, whole brain and craniospinal field. The radiation dose ranged from 40.8 to 59.4 Gy (Median 50.4 Gy). The median follow up was 36.5 months $(4\~172\;months)$. Results : An improvement or stability in the clinical symptoms was observed in 28 patients $(93.3\%)$ after the trial RT. Nineteen patients $(63.3\%)$ showed a partial or complete response by CT or MRI. The two-year and five-year survival rates of the patients were $66.7\%$ and $55.1\%$, respectively. No significant difference in the survival rates according to the degree of the radiological response was abserved after the trial RT. The results of univariate analysis showed that age, the primary site, the performance status $(KPS\geq70)$, the degree of response after completing RT and the RT field were significant prognostic factors affecting the survival and disease free survival rates (p<0.05). Conclusion : The clinical and histological characteristics of pineal region tumors are quite complex and diverse. Therefore, it is difficult to predict the histological diagnosis and the possibility of radiocurability only with the initial response to RT. We think that the development of less invasive histological diagnostic techniques and tailored treatment to the histological type of each tumor are needed.

SSI Effects on the Dynamic Response of Structures (구조물-지반 상호작용이 구조물의 동적거동에 미치는 영향)

  • 김용석
    • Computational Structural Engineering
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    • v.6 no.2
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    • pp.87-93
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    • 1993
  • Recently it is recognized that the effects of structure-soil interaction(SSI) on the response of structures are important in the dynamic analysis of structures. In this study, theoretical and experimental investigations were performed to study the SSI effects(mainly inertial interaction) on the dynamic response of buildings utilizing the finite element foumulation. Theoretical studies were performed with two idealized buildings(stubby one and slender one) built on the homogeneous soil layer and having the small embedment ratio. Experimental investigations were also carried out for two buildings built on the pile foundation in Mexico City, experienced the 1985 Earthquake. The results of this study show that the SSI effects are significant on the response of structures due to the change of fundamental frequency and effective damping ratio, and that it is necessary to include the SSI effects on the dynamic analysis of structures.

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Construction of the Authority Files Using Automatically Indexed Terms (자동색인어를 이용한 전거파일의 구축)

  • 한영균
    • Proceedings of the Korean Society for Information Management Conference
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    • 1994.12a
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    • pp.93-96
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    • 1994
  • 본 연구는 자동색인시스템의 색인기능을 통해서 추출된 색인어를 이용해서 검색시스템에서 요구되는 전거파일을 구축하는 작업의 효용성을 확인하기 위한 시험적 연구의 결과를 정리한 것이다. 언론연구원의 KINDS 서비스 시스템의 신문기사 데이터베이스에서 색인시스템을 통해 추출된 약 80만개의 색인어를 기본자료로 삼아 색인어를 하위분류하고, 그것을 이용한 전거파일 구축의 가능성을 타진해 본 것이다.

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A Experimental Study on the Repair Performance of Crack Using Chloride ion Penetration (염소이온 투과실험을 이용한 균열보수성능 평가에 관한 시험적 연구)

  • 심종성;문도영;김언경
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.11a
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    • pp.503-508
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    • 2001
  • With difference to strengthening which could be evaluated structural efficiency, it is hard to do quantitative repair efficiency evaluation achieved compressive strength test or appearance investigation. In this paper, chloride ion penetration test is exacted to core specimens picked from repaired structure for quantitative repair evaluation. The result of experimentation shows repair efficiency quantitatively by means of difference between penetration amount of chloride ion for repaired and unrepaired core specimens.

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