• Korean Journal of Food Science and Technology
• /
• v.28 no.4
• /
• pp.796-799
• /
• 1996

The antimutagenic properties of twenty-one strains of Bifidobacterium were examined using Salmonella typhimurium TA98 in an in vitro assay system. The mutagens utilized for testing included Trp-P-1 (3-amino-1, 4-dimethyl-$^{5}H-pyrido$ (4, 3-b) indole), benzopyrene, IQ (2-amino -3-methylimidazo [4,5-f] quinoline), and NQO. The lyophilized cells of strain showed inhibitory effect of 64, 38, 29 and 20% in average against Trp-P-1, benzopyrene, NQO and IQ, respectively. There was no marked variation between each strain or growth stage in the degree of antimutagenicity against Trp-P-1, benzopyrene and IQ. Twelve hour grown cells showed higher antimutagenicity against NQO than 5-day grown cells. The results indicate that Bifidobacterium cells had a antimutagenic effect against several well-known mutagens to some degree.

• Microbiology and Biotechnology Letters
• /
• v.12 no.4
• /
• pp.285-291
• /
• 1984

In making liquid yoghurt, the influences of proteolytic ability of lactic acid bacteria on acid production and on protein stability were investigated. L. bulgaricus CH-2, L. helviticus IAM 1042 and L. jugurti 3048 showed a comparatively high proteolytic activity in milk, while L. casei YIT 9018 did not show any marked proteolysis. Starter organisms having high proteolytic ability showed more rapid growth and acid production than those having low ability in milk. The most active proteolysis occurred during logarithmic growth phase of yogurt organisms, and most of the proteolysis took place in the first 24-48 hrs of incubation. Highly proteolysed yogurts made by L. bulgaricus CH-2, L. jugurti 3048, L. helviticus IAM 1042, L. acidophilus L-54 and L. casei 3012 had low protein solubility at pH 3.5 and had much protein precipitates during storage of product, but those having little protein hydrolysates made by L. casei YIT 9018 or artificial acidification showed no precipitation during keeping.

• Defense and Technology
• /
• no.8 s.138
• /
• pp.16-23
• /
• 1990

싱가포르 항공사는 프랑스 Aerospatiale Helicopter Division, CATIC(PRC)과 새로운 4~5인승 단발엔진 헬기를 공동 개발하기로 합의하였다. 잠정적으로 P120L이라고 명명된 이 새로운 항공기는 Gazelle이나 Lama 계열로서, Ecureuil 기를 보완하는 것으로 계획되어 있다. 실제 개발은 1990년 말 개념정의단계 완료후에 결정될 것이며, 첫 비행은 1993년, 인도시기는 1996년으로 예정되어 있다. P120L기에는 2가지 형이 있는데, 하나는 민수용이고 또 하나는 고성능 군용기이다. 기체 총 중량은 민수용은 2천kg, 군수용은 2천3백kg이다.

• Journal of Korean Ophthalmic Optics Society
• /
• v.11 no.3
• /
• pp.281-291
• /
• 2006

The aim of this study was performed the clinical test using Netspeg lens for good visual acuity on subjects with abnormal refraction status. The subjects of one hundreds adults (fifty males, fifty females, mean=21 years, range=19 to 24) were recorded. The subjects were researched the history including the systemic health, medication, genetics, allergy, systemic disease and ocular disease. The refraction test was recorded the monocular and binocular using objective method. Visual acuity was performed the binocular status using the Netspeg lens and CR-39. Stereopsis test was performed the titmus fly and TNO at near distance using Netspeg lens and CR-39. The P-VEP test was used the 16 pattern size(Bausch Lomb, production in USA) with three channels. Also Subjects viewed the p-vep stimulus with binocular vision through the corrected visual acuity using the Netspeg lens and CR-39. The contrast sensitivity test was performed the contrast sensitivity chart(pelli-Robertson, USA) at 1m distance using the Netspeg lens and CR-39. The ultrastructure of surface on the Netspeg lens and CR-39 was observed the SEM(JMS-5800, made in Japan). The results of this study was as follows: 1. In corrected visual acuity of abnormal refraction using the Netspeg lens and CR-39, the Netspeg lens wearer were acquired the good visual field and clear visual acuity comparative to CR-39 wearer in the subject vision test. however the comfort of visual acuity was similar results in the Netspeg lens and CR-39. Also the subjects of Netspeg lens wearer was good visual acuity more than CR-39 wearer and in the analysis of P-VEP, the amplitude of wave on Netspeg lens used appears to be better through the CR-39(p>0.5). Besides, on the contrast sensitivity, the Netspeg lens wearer was good results than CR-39. The value on stereopsis with TNO by Netspeg lens wearer was better than CR-39 in results. However, in the stereopsis test with Titmus, the Netspeg lens and CR-39 wearer was similar results. 2. The ultrastructure of Netspeg lens surface was the smooth and fine shape more than CR-39. Also, Netspeg lens have a fine line structure in ultrastructure. In conclusion, the results of this study conformed that the surface ultrastructure of Netspeg lens used is more specific pin hole design structure than CR-39. This study indicated that the vision of Netspeg lens used have a better than CR-39 in the corrected visual acuity for abnormal refraction eye. Therefore, In this paper, we suggested that the ultrastructure and line structure of Netspeg lens was related to good visual function. However the visual function of the aspheric Netspeg and ultra waterproof Netspeg lens was similar results.

• Journal of Haehwa Medicine
• /
• v.5 no.2
• /
• pp.497-497
• /
• 1997

간질성폐질변(間質性肺疾變)은 결체조직질병(結締組織疾病)의 상견(常見)되는 병발증(倂發證)이지만, 지금까지는 이상적(理想的)인 치료법(治療法)이 없었다. 본(本) 연구(硏究)는 본병(本病)의 병리기전(病理機轉)이 중의(中醫)에서의 "어혈(瘀血)"증(證) 상호(相互) 유사(類似)한 것으로부터 시작(始作)하여, 중의(中醫)의 "활혈화어법(活血化瘀法)"과 결합(結合)하여 치료(治療)하면서 환자(患者)의 폐기능(肺氣能) 검사결과(檢査結果)의 변화(變化)를 추적(追跡)해, 그 치료효과(治療效果)에 대(對)한 평가(評價)를 내리는 작업(作業)으로 이루어졌다. 먼저 풍습과(風濕科)에 의뢰(依賴)하여 결체조직질병(結締組織疾病)에 간질성폐병(間質性肺病)이 병발(倂發)한 환자(患者)를 선별(選別)한 후(後)에, 서의치료(西醫治療) 통(通)해서 그 원발성(原發性) 질병(疾病)이 은정(隱靜)한 상태(狀態)에까지 이르도록 한 후(後), 필요(必要)한 최저량(最低量)의 서의약(西醫藥)만을 유지(維持)케 하였다. 환자(患者)의 의사(意舍)에 따라서 두 개의 조(組)로 나누어, 실험군(實驗群)은 중의(中醫)에서 회진(會診)하고, Raynaud 증후군(症候群)의 유무(有無)에 따라서, 당귀사역탕(當歸四逆湯) 혹(或)은 혈부축어탕(血府逐瘀湯)을 농축분제(濃縮粉劑)로 투여(投與)하며 연속(連續)하여 6개월간(個月間) 치료(治療)하였다. 대조군(對照群)의 경우(境遇)에는 중의(中醫)가 회진(會診)하지 않았다. 14개월(個月)동안 모두 실험군(實驗群) 23례(例)와 대조군(對照群) 16례(例)를 대상(對象)으로 연구(硏究)를 하였는데, 모두 여성환자(女性患者)였다. 압축성폐용량(壓軸性肺用量)(FVC), 폐총용량(肺總用量)(TCL), carbon monoxide에 대(對)한 폐(肺)의 확산능력(擴散能力)(DLCO), 그리고 폐포공기량(肺泡空氣量)(VA)에 대(對) DCLO의 비(比)를 지표(指標)로 삼아, 폐기능(肺氣能)의 손상정도(損傷程度)에 따라서 box plot으로 분석(分析)하고, 폐기능(肺氣能)의 손상(損傷)을 측정(測定)하는 시스템을 만들었다. 실험결과(實驗結果), 실험군(實驗群)이 대조군(對照群)에 비(比)해서 치료(治療) 전(前)보다 명현(明顯)한 개선(改善)이 있었다. 폐기능(肺氣能)을 검사(檢査)한 수치(數値)들을 일반적(一般的)으로 통계처리(統計處理)한 것을 응용(應用)하고, TCL과 FVC의 모형식(模型式)을 만든 결과(結果), 실험군(實驗群)에서 FVC가 치료과정(治療過程)의 기간(其間)과 정비례(正比例)하여 향상(向上)되고, 또한 치료효과(治療效果)가 명현(明顯)하게 나타나기 시작(始作)하는 시기(時期)가 중의(中醫) 치료과정(治療過程)을 거친 실험군(實驗群)의 제(第)12개(個)에서 DLCO와 DLCO/VA의 향상(向上)이 나타나는 시기(時期)와 거의 일치(一致)하는 것을 발견(發見)하였다.

• Korean Journal of Food Science and Technology
• /
• v.44 no.6
• /
• pp.772-778
• /
• 2012

This study was conducted to investigate physiologically active components and antioxidant capacity of grapevine leaves at growth stages. The leaves from two strains of grapevine, 'Campbell Early' and 'Rosario Bianco', were collected at five different growth stages (leafing, blossom, fruiting, coloring, and maturity). Total flavonoid content was higher in leafing stage than the other stages and gradually decreased during growing. Total phenol content was higher in 'Campbell Early' than in 'Rosario Bianco'. Hydroxyl radical scavenging ability increased in the leafing stage and decreased during growing. The electron donating ability was higher in 'Campbell Early' then 'Rosario Bianco' until blossom stage. Leaves from 'Campbell Early' showed higher total antioxidant capacity than those from 'Rosario Bianco'. According to the above results, grapevine leaves until the blossom stage would possess strong antioxidant activity by physiologically active components such as polyphenol compounds. Therefore, these results suggest that young grapevine leaves can be used as materials for the development of functional foods.

• Journal of Korean Ophthalmic Optics Society
• /
• v.15 no.1
• /
• pp.47-53
• /
• 2010

Purpose: This study was performed to achieve an acceptable piggyback fit utilizing each subject's own GP lenses, in subjects with regular low myopic astigmatism. Methods: A randomized, prospective study of 15 subjects with the diagnosis of low myopic astigmatism was conducted. Nine subjects were female and 6 were male, and mean age was: 23.73${\pm}$1.68 years. Subjects were evaluated before participate on this study and then also evaluated with period of at two hours and two weeks after obtaining their lenses. All subjects were submitted to the following tests: measurement of comfort level by means of the analogical visual scale, best corrected visual acuity and over-refraction at distance. contrast sensitivity and stereo acuity. After evaluating the fit of plano soft lens, we applied each subject's own GP lens on top. Results: Vision, visual performance and satisfaction of piggyback contact lens system were stable, if not improved, for the 15 subjects when the data was compared to the patients' wear of rigid gas permeable contact lenses. Fit with a piggyback system had the same or improved comfort, visual acuity and contrast sensitivity compared to previous GP lens wear alone. The visual acuity, contrast sensitivity and stereo acuity did not show differences in relation to the studied lens type. Conclusions: These results suggest that it is possible to achieve a successful piggyback lens fitting utilizing a patient's own GP lens. The piggyback lens system satisfied the visual performance and visual requirements of this subject with GP lens alone for the correction of low myopic astigmatism.

• Journal of Korean Ophthalmic Optics Society
• /
• v.20 no.4
• /
• pp.477-484
• /
• 2015

Purpose: This study was investigated to evaluate the effect of the variation of the face form angle(FFA) of spectacle frame on the visual acuity and the visual function. Methods: The visual acuity, the contrast sensitivity, the stereopsis, and the phoria were measured with the spectacle frame whose the FFA is at $5^{\circ}$ and $25^{\circ}$ and the surveys were conducted on subjective symptoms. Here, 30 adults (14 men and 16 women, average age:$25.46{\pm}3.9$), who did not have ocular diseases and were fully corrected in case of having had refractive error, were to act as experimental subjects for this measurement. Results: The visual acuity and the contrast sensitivity was decreased and the phoria was tended to increase to the esophoria direction at the FFA $25^{\circ}$ than at the FFA $5^{\circ}$. The stereopsis was significantly reduced at the FFA $25^{\circ}$ than at the FFA $5^{\circ}$. Also when the FFA was larger, the higher the degree of refractive error was, the more the increase of the subjective symptoms such as being blurred characters, being disturbed head, and having sore eyes was, which reveals a statistically significant correlation between them. Conclusions: If the FFA increases, the visual acuity, the contrast sensitivity and the stereopsis was found to decrease and the phoria to increase to the esophoria direction. Therefore it shows that the variation of the FFA of spectacle frame can influence the visual acuity and the visual function.

• Journal of Korean Ophthalmic Optics Society
• /
• v.7 no.1
• /
• pp.9-13
• /
• 2002

It is well known that the maximum amplitude of accommodation decreases with increasing age.(Presbyopia). With single vision lenses presbyopia can be corrected only for one viewing distance. With progressive power lenses presbyopia can be corrected for all viewing distances. But there are some other changes in the visual system with age which can not be corrected by spectacle lenses. Pupillary diameter decreases and the light transmission of the ocular media decreases. Therefore old people need more light, they need better illumination. Cone density in the retina decreases, this is only one example for changes in the sensory system. These changes in the visual system cause changes in visual functions. At the age of 80 visual acuity has decreased to half. Contrast sensitivity for gratings decreases mainly for high spatial frequencies very important is the increase of stray light in the ocular media and therefore the increase of glare. Veiling luminance increases by a multiple of approximately 4, Dark adaptation gets slower and light sensitivity is approximately 2 log units (factor 100) less when the eye is completely dark adapted. Also colour vision gets worse, especially at low luminances. Elderly people have problems with visual tasks which require divided attention between foveal and peripheral vision. An example is the measurement of the useful field of view. This useful field of view be expanded (improved) by visual training.

• Food Science and Preservation
• /
• v.18 no.1
• /
• pp.13-17
• /
• 2011

The proximate composition, and the levels of total phenols, phenolic acids, and DPPH radical scavenging activity in Cheongdobansi persimmon fruits assayed during development (from July to October), were investigated. All of moisture, crude protein and crude fiber contents decreased as picking time was delayed, however, crude fat content rose. Crude fiber content increased after September. Total phenol content tended to fall during development. The principal phenolic acids were chlorogenic acid, caffeic acid, p-coumaric acid and salicylic acid; the level of each phenolic acid tended to decrease during development. DPPH radical scavenging activity fell as picking time was delayed. Thus, harvest time influenced the levels of chemical components and the antioxidative properties of persimmon fruit. It follows that unripe fruit may be utilized as a raw material yielding many useful products.