• Title/Summary/Keyword: 시간의존 Cox 모형

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Propensity score methods for estimating treatment delay effects (생존자료분석에서 성향 점수를 이용한 treatment delay effect 추정법에 대한 연구)

  • Jooyi Jung;Hyunjin Song;Seungbong Han
    • The Korean Journal of Applied Statistics
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    • v.36 no.5
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    • pp.415-445
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    • 2023
  • Oftentimes, the time dependent treatment covariate and the time dependent confounders exist in observation studies. It is an important problem to correctly adjust for the time dependent confounders in the propensity score analysis. Recently, In the survival data, Hade et al. (2020) used a propensity score matching method to correctly estimate the treatment delay effect when the time dependent confounder affects time to the treatment time, where the treatment delay effects is defined to the delay in treatment reception. In this paper, we proposed the Cox model based marginal structural model (Cox-MSM) framework to estimate the treatment delay effect and conducted extensive simulation studies to compare our proposed Cox-MSM with the propensity score matching method proposed by Hade et al. (2020). Our simulation results showed that the Cox-MSM leads to more exact estimate for the treatment delay effect compared with two sequential matching schemes based on propensity scores. Example from study in treatment discontinuation in conjunction with simulated data illustrates the practical advantages of the proposed Cox-MSM.

Analysis of stage III proximal colon cancer using the Cox proportional hazards model (Cox 비례위험모형을 이용한 우측 대장암 3기 자료 분석)

  • Lee, Taeseob;Lee, Minjung
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.2
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    • pp.349-359
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    • 2017
  • In this paper, we conducted survival analyses by fitting the Cox proportional hazards model to stage III proximal colon cancer data obtained from the Surveillance, Epidemiology, and End Results program of the National Cancer Institute. We investigated the effect of covariates on the hazard function for death from proximal colon cancer in stage III with surgery performed and estimated the survival probability for a patient with specific covariates. We showed that the proportional hazards assumption is satisfied for covariates that were used to analyses, using a test based on the Schoenfeld residuals and plots of the Schoenfeld residuals and $log[-log\{{\hat{S}}(t)\}]$. We evaluated the model calibration and discriminatory accuracy by calibration plot and time-dependent area under the ROC curve, which were calculated using 10-fold cross validation.

A Study on the Effects of Livestock Disease News on the Purchase of Beef and Pork (축산 질병 보도가 소, 돼지고기 구입에 미치는 영향에 관한 연구)

  • Shin, Jeong-Seop
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.10
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    • pp.425-432
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    • 2019
  • This study examined the effects of livestock disease news, such as foot-and-mouth disease (FMD), collected by the Korea Press Foundation on BIGKinds on the consumption of beef and pork. The consumer purchase data were obtained from the Rural Development Administration's Agrifood consumer panel data. Survival analysis showed that the FMD news noted beef and pork, and the first purchase rate decreased due to FMD news. The time-dependent Cox proportional hazards model revealed all models to be significant. FMD news was significant in each model. In 2010, the Hazard Ratio of domestic and imported pork was 0.999, and the first purchase rate decreased 0.999 times for each additional FMD news item. On the other hand, the Hazard Ratio of pork in 2015 was 1.001, and the first purchase rate increased. In the case of beef, results similar to pork were shown. This study estimated the impact of consumer meat consumption disease news on the first purchases according to origin and meat. These results provide the necessary information for rational production and consumption activities. In addition, it can also be used for promotion by estimating the duration of livestock disease news.

Comparative Analysis for Survival Period of Innovative SMEs and General SMEs (혁신형 중소기업과 일반 중소기업의 생존기간 비교분석)

  • Lee, Jun-won
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.1
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    • pp.225-236
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    • 2023
  • Policy implications were derived by comparing/analyzing innovative SMEs and general SMEs that obtained innovation certification from 2015 to 2021 in terms of survival period. Work experience, scale (employment, capital and debt size, sales and operating profit) Korean standard industry classification (2 digit) was used to select general SMEs similar to innovative SMEs. Survival period was calculated by defining suspension, closure and overdue equivalent to default as events. As a result of the survival analysis, innovative SMEs showed a 9.8% reduction in the risk of delinquency compared to general SMEs, indicating that the survival period of innovative SMEs was significantly longer. In addition, it was found that the work experience and size (employment, capital) of SMEs had a positive effect on the survival period, but debt had a negative effect on the survival period. This means that the innovation certification system centered on innovation capabilities and future growth potential is a significant indicator in terms of survival period. As a result, it was concluded that the benefits and support policies provided by the innovation certification system need to be more systematic and sophisticated by reflecting the work experience and industry for the actual growth and survival of SMEs.

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