• Korean Journal of Microbiology
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• v.45 no.1
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• pp.54-57
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• 2009

Fermented soybean, Chungkookjang has diverse bioactive compounds including antioxidants and peptides. Ethanol extract from Chungkookjang exhibited absorbance of 0.55 at 285 nm, where amino acids and peptides containing phenol are known to exist. Antioxidant activity of Chungkookjang was determined using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. With increasing concentrations of ethanol extracts, their antioxidant activities increased. Blood pressure was determined every two hours after taking raw Chungkookjang which does not contain salts. In 6 h, systolic blood pressure dropped by 14 mmHg, and diastolic one dropped by 8 mmHg, which was statistically significant. Daidzein, antioxidants, angiotensin I-converting enzyme (ACE) inhibitor such as Lys-Pro which are rich in Chungkookjang might contribute to the reduction of blood pressure.

• Journal of Preventive Medicine and Public Health
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• v.24 no.4 s.36
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• pp.496-506
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• 1991

A cross-sectional study was conducted to investigate the effect of long term noise exposure on blood pressure among steel mill workers. The workers participated in periodic medical examinations performed from August 27 to September 6 in 1990. Examined were 1,034 workers with high-level noise exposure(average $91.8{\pm}5.2dB(A)$) and 390 workers with low-level noise exposure(average $75.2{\pm}4.6dB(A)$). No significant difference was found in systolic or diastolic flood pressure between the two exposure groups. Prevalence of hypertension (${\geq}160mmHg\;systolic\;or{\geq}100mmHg\;diastolic$) was higher in a younger age group (${\leq}40$ years old) of high-level noise exposure than of low-level noise exposure. However, the difference was not statistically significant. Furthermore, in younger ages, prevalence of hypertension appeared to be higher in the hearing loss group (${\geq}25dB\;at\;1000Hz\;or{\geq}40dB$ at 4000Hz in at least one ear) than in the normal hearing group. From multiple regression analysis, hearing loss, body mass index, age, alcohol and family history of hypertension were proven to be predictors of diastolic blood Pressure (p<0.02). When regression was performed for each age group, hearing loss was a strong predictor of diastolic pressure in the younger age group (p<0.01).

• Journal of the Korea Convergence Society
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• v.9 no.11
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• pp.203-208
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• 2018

The purpose of this study was to investigate whether there is a relationship between pulmonary function, serum lipid and pulse pressure, which is a risk factor of cardiovascular disease, in subjects with 109 office workers(51 males and 58 females) be at Seoul, Korea. The mean age of the subjects was $43.44{\pm}7.23$ years old (male $43.44{\pm}7.27$, fenale $49.1{\pm}11.5$). The subjects' height, weight, BMI, systolic and diastolic blood pressures were measured and there was statistical difference between men and women.The mean pulse pressure of the subjects was $47.82{\pm}9.02mmHg$, and the mean of FVC was $84.26{\pm}9.91%$. There was no difference between men and women in both. There was a positive correlation between pulse pressure and systolic blood pressure in males (p<0.01) and females (p<0.01), and FVC and HDL in males were positively correlated (p<0.05). Pulse pressure and %FVC were negatively correlated (r =-0.267, P<0.01). Pulse pressure and %FVC were negatively correlated (r =-0.267, P<0.01). Regression analysis showed that PP was the independent affected %FVC. Therefore, pulse pressure and %FVC may be useful as a predictor of cardiovascular disease in middle-aged subjects with normal, suggest a long-term convergence follow-up is warranted to elucidate the incidence of cardiovascular disease.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.12
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• pp.5849-5859
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• 2012

The aim of this study was to find out the impact of age and hypertensive status on postprandial hypotension(PPH). Twenty-six hypertensive elderly ($77.7{\pm}7.2$ years old), twenty-five normotensive elderly ($80.2{\pm}6.8$ years old) and twenty-six young adults ($20.0{\pm}1.5$ years old) took part in the study. The blood pressure (BP) and heart rates (HR) were measured every 15 minutes, from 30 minutes before a meal to 90 minute after a meal in sitting position, using an ambulatory blood pressure monitor. In the hypertensive group, postprandial reduction in systolic BP continued from 30minutes to 90minutes. The reductuion rate of systolic BP of hypertensive elderly group was significantly greater than other groups (p<.05). However, there were no significant differences in trend of HR change between the groups (p=.082). The incidence of PPH was significantly higher in the hypertensives than other groups (73.1% vs 24% vs 0%, respectively, p=.001). In conclusion, age and hypertensive status had a significant impact on PPH. Elderly persons require more intensive BP monitoring and nursing intervention.

• Science of Emotion and Sensibility
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• v.11 no.2
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• pp.235-244
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• 2008

This study is to develop automatic extraction system of continuous blood pressure using ECG (Electrocardiogram) and PPG(Photoplethysmography) for u-health care technology. PTT (Pulse Transit Time) was determined from peak difference between ECG and PPG and its inverse made to get blood pressure. Since the peaks were vulnerable to be contaminated from noise and variation of amplitude, this study developed the adaptive algorithm for peak calculation in any noise condition. The developed method of the adaptive peak calculation was proven to make the standard deviations of PPT decrease to 28% and the detection of noise increase to 18%. Also, the correlation model such as blood pressure = -0.044 $\cdot$ PTT + 133.592 has successfully been determined for predicting the continuous pressure measured without using cuff but with using PPG and ECG, only.

• The Korean Journal of Applied Statistics
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• v.21 no.6
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• pp.1027-1035
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• 2008

This research is aimed to investigate the effect of repetitive dive on physiological reactions, change of stress hormones in no decompression limit of sport SCUBA dive, an emerging recreational activity recently. In order to compare physiological reactions prior to and after the initial dive and after repetitive dive at a certain depth of a place, eight adult male divers with more than forty dives, who reside in Busan and were certified, were selected. The research results obtained from the procedures described above are follows: First, for physiological reactions, heart rates, temperatures, and systolic blood pressures had significant difference among prior to and after the initial dive and after the repetitive dive, while diastolic blood pressures did not show remarkable difference as it increased before and after the first dive but decreased following the repetitive dive again. Second, for change of stress hormones, it was not significantly different prior to and after the initial dive and following the repetitive dive, as well as before and during the first dive and the repetitive dive.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.1
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• pp.1-10
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• 1996

뇌졸중이라고 진단된 입원 환자 26명을 대상으로 3일동안 섭취한 식이와 24시간 뇨와 혈액을 수집하고 혈압을 측정하여 나트륨, 칼륨, 캄슘, 마그네슘의섭취 수준에 다른 뇨중 배설량과 혈중 수준을 관찰하고 이들과 혈압과의 관계를 알아봄으로써 뇌졸중 환자를 포함한 고혈압 관리의 치료식이를 제공하는데 기초자료로 사용하고자 실시간 연구결과를 요약하면 다음과 같다. 1. 대상자들의 평균 연령은 남녀 각각 52.6세, 58.5세였으며 평균 BMU는 남녀 각각 21.6, 22.4였다. 입원 당시 평균 혈압은 남녀 각각 147.3/90.9mmHg, 162.7/102.0mmHg였고, 실험 종료일의 평균 혈압은 남자의 경운 124.6/80.8mmHg 였고 여자 대상자는 137.7/91.3mmHg 였다. 2. 1일 평균 나트륨, 칼륨, 칼슘, 마그네슘의 섭취 향은 96.7$\pm$30.7mEq,64.8$\pm$19.0mEq, 431.3$\pm$227.1mg, 333.9$\pm$145.9mg이었다. 3. 1일 평균 뇨중 나트륨, 칼륨, 칼슘, 마그네슘의 배설량은 76.7$\pm$28.2mEq, 33.9$\pm$16.6mEq, 65.6$\pm$34.0mg, 96.5$\pm$58.0mg이었다. 4. 평균 혈청내 나트륨, 칼륨, 칼슘, 마그네슘의 함량은 137.8$\pm$4.3mEq/l, 3.7$\pm$0.5mEq/l, 7.6$\pm$0.8mg/dl, 2.2$\pm$0.2mg/dl로써 칼슘 농도가 정상수준에 비해 비교적 낮은 것으로 나타났다. 5. 혈압과 무기질과의 관계에서 수축시 혈압의 증가시 뇨중 칼륨 배설이 증가함으로써 수축기 혈압과 뇨중 칼륨 배설량 사이에 유의적인 부의 상관관계가 나타났다. (p<0.05). 이상과 같은 입원중인 뇌졸중 환자의 뇨중 나트륨과 칼륨의 배설률 및 혈청과 뇨중 칼슘 배설수준이 정상인 보다 낮은 수준이었으며, 칼륨은 뇌졸중 환자의 혈압관리에 효과적이 무기질로 작용할 가능성이 보여지므로 고혈압관리를 위한 식사 처방시 이들 무기질에 대한 고려가 있어야 할 것으로 사료된다.

• Proceedings of the Korea Information Processing Society Conference
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• 2021.05a
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• pp.551-552
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• 2021

본 논문에서는 촬영한 피부 영상(얼굴, 손 등)을 이용한 생체신호(맥박, 호흡, 혈압, 체온 등) 측정 S/W 기술을 제안한다. 기존의 생체신호 측정 기술은 다양한 센서(PPG, 압력 센서, 혈압계, 체온계 등)가 탑재된 측정 장치를 이용하여 상태를 측정하고 이를 진단하는 연구들이 진행되어 왔다. 각 각의 생체신호를 측정하기 위해서는 별도로 구비된 측정 장치들을 이용하여 개별적으로 생체신호를 측정하고 확인하여야 한다. 제안된 기술은 스마트 디바이스에 생체신호 측정 S/W의 설치만으로 카메라로 촬영한 피부 영상의 피부 관심 영역에서 계산된 색상 데이터를 이용하여 다양한 생체신호를 언제 어디서나 실시간으로 측정할 수 있으며, 생체신호 측정 성능 평가 결과 맥박수 2.63%, 호흡수 5.98%, 이완기 혈압 2.48%, 수축기 혈압 5.23% 및 체온 0.25%의 오차율이 계산되었다.

• The Journal of the Korea Contents Association
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• v.16 no.2
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• pp.666-672
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• 2016

We extracted 50 LVH patients out of 30'~80's who performing ECG and echocardiography examination. We used Devereux's theory to examinate LVH with echocardiography and used Sokolow-Lyon's theory to examinate LVH with ECG. We used regression and correlation analysis by SPSS, used ROC curve analysis to decide predominance of two ways of .Age, BMI, SBP and DBP whice are the danger factors of LVH and standard value of LVH diagnosis examination seems correlated. Out of 50 LVH patients, 50 patients were diagnosed LVH by echcardiography examination and only 21 patients were diagnosed LVH by ECG examination. Also echocardiography was AUC 99%, sensitivity 96%, singularity 95%, accuracy 95.5%. And ECG was AUC 76%, sensitivity 62%, singularity 76%, accuracy 68%.By comparing accuracy between echocardiography and ECG in diagnosing LVH, we could tell echocardiography was examination with higher accuracy. Therefore, if one was diagnosed with summit on 1st examination with ECG, considering age, body mass index, systolic blood pressure and dilator blood pressure, should offer echocardiography examination.

• The Journal of Korean Academic Society of Nursing Education
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• v.13 no.1
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• pp.95-104
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• 2007

연구목적: 고혈압환자의 효과적인 자가관리 간호중재를 개발하는데 필요한 기초자료로 혈압자가측정(self-monitoring of blood pressure)에 대한 특성, 장점, 범위 및 제한점을 파악한다. 연구방법: 1996년부터 2005년까지 PubMed에 수록된 고혈압환자의 자가관리 방법중 혈압자가측정방법이 포함된 외국의 연구를 중심으로 체계적인 고찰을 실시하였다. 전체 69개 자가관리방법을 적용한 논문 중에서 혈압자가측정이나 가정에서의 혈압측정(home monitoring)에 대한 45개 논문을 선정하여 분석하였다. 연구결과 전반적으로 혈압자가측정 방법은 고혈압환자의 혈압조절을 향상시키는 효과가 유의한 것으로 나타났다. 환자가 혈압을 자가측정한 방법에서 평균 혈압, 수축기 혈압, 맥압이 유의하게 감소한 것으로 보고되었다. 장기적 프로그램에서 혈압조절율이 향상되거나, 이완기혈압의 감소효과도 보고되었다. 혈압자가측정의 기준치는 연구마다 일치하지는 않았지만 135/85mmHg 수준이 정상혈압의 상한수준으로 제시되었다. 일부 연구에서는 가정 내 혈압측정이 24시간혈압측정을 대체하는 방법으로 추천되었다. 보다 정확한 혈압자가측정을 위해서 신뢰성 있는 혈압측정기구의 사용과 정확한 측정방법이 환자들에게 교육될 필요가 있다. 결론: 혈압자가측정은 고혈압환자의 혈압조절에 유용한 방법으로 고찰되었다. 또한 고혈압의 진단, 혈압치료와 고혈압 약물복용 행위를 향상시키는 교육적 효과도 긍정적으로 나타났다. 따라서 고혈압환자를 위한 효과적인 자기조절프로그램에 혈압자가측정법을 포함하는 것이 추천되며, 추후 한국에서 시도된 관련 연구에 관한 문헌고찰의 비교연구가 필요하다.