• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.3
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• pp.464-468
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• 2003

The antihypertensive and cholesterol- lowering effects of Monascus koji (M. koji) prepared with Monascus ruber IFO32318 were examined in spontaneously hypertensive rats (SHR). Control was fed a normal diet and groups I, II or III were fed diets containing 0.03%, 0.1% or 0.3% M. koji for 8 weeks, respectively. After 8 weeks, all animals were fed normal diets in the following 2 weeks. The blood pressure of rats fed M. koji added diets were significantly attenuated as compared with control and the diet containing high concentration of M. koji had a tendency of stronger antihypertensive effect. These differences lasted throughout the experimental period when they were fed experimental diet. For 2 weeks after the 8 weeks of experimental diet all groups were fed the same normal diet and the differences of blood pressure caused by M. koji disappeared. In rats fed the M. koji added diet, the serum total cholesterol (TC), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C) were not differed compared with control, but VLDL cholesterol (VLDL-C) was significantly lowered. M koji also significantly decreased serum risk factors, both TC/HDL-C ratio and non HDL-C/HDL-C ratio. Consequently, it is suggested that M. koji may play an important role to attenuate hypertension and to improve serum lipid Profiles.

• Journal of Biomedical Engineering Research
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• v.24 no.2
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• pp.113-119
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• 2003

In this paper we introduced optimized deformed shape to prevent the blood vessel disease caused by the discord of deformed shape in the end-to-end anastomosis. This study considered the preliminary deformed shape induced by suture in the anastomosis of artery and PTFE, artificial blood vessel, with different diameters. Then we analyzed the final deformed shape of the anastomotic part under the systolic blood pressure. 120mmHg(16.0kPa). The final deformed shape of the anstomotic part was analyzed with respect to the change of initial diameter ratio(R$_{I}$) and the PTFE thickness. Equivalent and circumferential stresses induced by the systolic blood pressure in the anastomosis were also analyzed with respect to the initial diameter ratio(R$_{I}$). The results obtained were as follows : 1. Considering the preliminary deformed shape induced by suture and the systolic pressure in the anastomosis, not intimal hyperplasia, the optimal initial diameter ratio(R$_{I}$) was 1.073. 2. As the initial diameter ratio(R$_{I}$) became larger, higher equivalent and circumferential stresses were induced. And all the maximum stresses occurred on the side of PTFE 0.4mm apart from the anastomosis.

• Journal of Digital Convergence
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• v.15 no.1
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• pp.571-581
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• 2017

The purpose of this study was to investigate the effects of virgin coconut oil supplementation and complex exercise on body composition, oxidative stress and blood pressure in the middle-aged women with metabolic syndrome. As a result, weight and body fat in coconut oil+complex exercise and coconut oil group are significantly decreased after the program. BMI and WHR in coconut oil+complex exercise group are significantly decreased after than before the program. MDA in coconut oil+complex exercise and coconut oil group is significantly decreased after the program. SOD in coconut oil+complex exercise and coconut oil group is significantly increased after the program. Systolic blood pressure in coconut oil+complex exercise and coconut oil group is significantly decreased after than before the program. Diastolic blood pressure in coconut oil+complex exercise group is significantly decreased after than before the program.

• Journal of Preventive Medicine and Public Health
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• v.17 no.1
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• pp.25-29
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• 1984

To assess the effect of noise on the blood pressure of workers, 70 weaving and 70 refining female workers in 15 to 24 years of ages were tested for the changes of blood pressure before and after exposure to the noise. The noise levels at work place were 99 dB (A) for weavers and 80 dB(A) for refiners. The mean age of refiners was 17,7 years and that of weavers was 18.6 years, and the difference in mean ages was statistically significant (p<0.05). The means of heights, weights and working durations were not significantly different between two groups. The mean systolic blood pressure of the weavers was 112.5mmHg before exposure to the noise and it was increased to 115.7mmHg after exposure to 99 dB(A) of noise for 30 minutes, and the mean diastolic blood pressure from 71.6mmHg to 74.1mmHg. These increments of blood pressure were statististically significant (p<0.05). The mean systolic blood pressure of the refiners was decreased from 108.9mmHg to 106.7mmHg after exposure to 80 dB(A) of noise for 30 minutes, and the mean diastolic blood pressure from 67.3mmHg to 67.1mmHg. These changes of blood pressure were not statistically significant. The mean systolic and diastolic blood pressure of the weavers before exposure to the noise were significantly higher than that of refiners (p<0.05). The difference of blood pressure between refiners and weavers was significantly associated with noises (p<0.05), and not ages and their interactions. The study results support the hypothesis that exposure to excessive noise increases the blood pressure of workers.

• Research in Community and Public Health Nursing
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• v.14 no.4
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• pp.568-578
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• 2003

This study was conducted to estimate the effects of self-care program on knowledge and symptoms related hypertension self-care and physiological index in essential hypertensive patients aged between 35-74 year. The subjects for the experiment group and the control group of this study were 70 men and women selected through random sampling from adults at Sangju Red Cross Hospital in Gyeongsanbuk-do, and the experiment was carried out during the period from the 15th of September to the 30th of April in 2002. This study measured systolic and diastolic blood pressure (SBP, DBP, the mean value of the two measures) and total cholesterol (TC) and surveyed the subjects' diet and life style in relation to hypertension using a self-report questionnaire. In order to study the significance of the effects of self-care program, the author carried out t-test, paired t-test, ANCOVA, chi-square analysis and effectiveness index (EI) analysis. Results of the study are as follows: The experiment group got higher mean scores than the control group in the degree of low sodium intake and the degree of high calcium and high potassium intake, and the difference was statistically significant(P<0.05). The effectiveness index of the self-care program in smoking was 0.797 at the 1st posttest and 0.601 at the 2nd posttest, and in physical activities 0.600 at the 1st posttest and 0.849 at the 2nd posttest. The rate of regular antihypertensive drugs intake of the experimental group was higher than that of the control group. and the effectiveness index of the self-care program was 0.715. The mean score of the systolic blood pressure of the experimental group was lower than that of the control group, and the difference was statistically significant(P<0.05). In conclusion, these findings support usefulness of self-care programs in reducing systolic blood pressure and in promoting self-care related to diet and life style for treating and preventing hypertension.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.7
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• pp.1095-1101
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• 2003

This study was carried out to investigate the effect of Gastrodiae Rhizoma (G. Rhizoma) on blood pressure-lowering in spontaneously hypertensive rats (SHR) fed high-fat diet supplemented with 10% (w/w) of lard during the experimental period of 8 weeks. Forty of male SHR weighing approximately 100 g were randomly divided into eight groups; A: negative control (lard 10%), B: positive control (lard 10% ＋ basal diet ＋ 5 brix water extract), C: lard 10% ＋ 1% G. Rhizoma powder, D: lard 10%＋5% G. Rhizoma powder, E: lard 10%＋2 brix 50% ethanol extract, F: lard 10%＋10 brix 50% ethanol extract, G: lard 10%＋2 brix water extract, H: lard 10% ＋ 10 brix water extract. A gain in weight did not differ significantly among dietary groups, but a little higher in control groups than in G. Rhizoma dietary groups. Except for spleen, weights of liver, kidney and testis are significantly different among dietary groups. Serum total cholesterol concentration was markedly higher in control groups than in G. Rhizoma groups (p<0.05), however, there was no significant difference in serum triglyceride. Except for negative control (A) and group D, serum HDL concentration was significantly higher in G. Rhizoma groups (p<0.05). On the other hand, serum LDL concentration was significantly higher in two control groups (A, B) and markedly lower in E and G groups of hot water extract of G. Rhizoma (p<0.05). Reference systolic blood pressure (BP) showed average 185.7$\pm$5.8 mmHg for 4 weeks after feeding high-fat diet, and the pressure was measured on every 7 days intervals after feeding of G. Rhizoma diet. Comparing with reference BP before feeding of G. Rhizoma diet, the groups of 50% ethanol (E, F) and water (G) extracts on BP level after 28 days were shown to be reduced at 16.8, 20.2 and 11.7 mmHg, respectively. When the pressure (187 mmHg) of group A was considered as 100%, the reduction rate of BP in group F was 11% (20.5 mmHg). These results indicated that the groups treated with ethanol extracts of G. Rhizoma showed to have lower blood pressure level compacred to the groups treated with whole powder or water extracts of G.Rhizoma in SHR fed with high-fat diet.

• Tuberculosis and Respiratory Diseases
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• v.46 no.6
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• pp.846-855
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• 1999

Background : Secondary pulmonary hypertension is an important final endpoint in patients with chronic hypoxic lung disease, accompanied by deterioration of pulmonary hemodynamics. The clinical diagnosis of pulmonary hypertension and/or cor pulmonale could be difficult, and simple noninvasive evaluation of pulmonary artery pressures has been an relevant clinical challenge for many years. Doppler echocardiography might to be a more reliable method for evaluating pulmonary hemodynamics in such patients in terms of the accuracy, reproducibility and easiness for obtaining an appropriate echocardiographic window than M-mode echocardiography. The aim of this study was to assess echocardiographic parameters associated with pulmonary arterial hypertension, defined by increasing right ventricular systolic pressure(RVSP), calculated from trans-tricuspid gradient in patients with chronic hypoxic lungs. Method : We examined 19 patients with chronic hypoxic lung disease, suspected pulmonary hypertension under the clinical guidelines by two dimensional echocardiography via the left parasternal and subcostal approach in a supine position. Doppler echocardiography measured RVSP from tricuspid regurgitant velocity in continuous wave with 2.5MHz transducer and acceleration time(AT) on right ventricular outflow tract in pulsed wave for the estimation of pulmonary arterial pressure. Results : On echocardiography, moderate to severe degree of pulmonary arterial hypertension was defined as RVSP more than 40mmHg, presenting tricuspid regurgitation. Increased right ventricular endsystolic diameter and shortened AT were noted in the increased RVSP group. Increased RVSP was correlated negatively with the shortening of AT. Other clinical data, including pulmonary functional parameters, arterial blood gas analysis and M mode echocardiographic parameters were not changed significantly with the increased RVSP. Conclusion : These findings suggest that shortened AT on pulsed doppler can be useful when quantifying pulmonary arterial pressure with increased RVSP in patients with chronic lung disease with hypoxemia. Doppler echocardiography in pulmonary hypertension of chronic hypoxic lungs is an useful option, based on noninvasiveness under routine clinical practice.

• Journal of Digital Convergence
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• v.12 no.11
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• pp.487-497
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• 2014

This study was to examine the effect of the Self-efficacy Promotion Exercise Program to the elderly hypertensive with Stage 1. This research was the quasi-experimental study. The Self-efficacy Promotion Exercise Program combined to Aerobic exercise which is incrementally at a level of 40~60% HRmax and the source of the Self-efficacy Promotion Exercise. This research was carried out to experimental(33 patients) and control(32 patients), 60 minutes per day, 3 times a week for 12 weeks. The Self-efficacy Promotion Program was effect on enhancing the general(p<.001) and exercise self-efficacy(p<.001), the self-care behaviors(p<.001) and decreasing the systolic blood pressure(p<.001) to the elderly hypertensives. The 12 weeks Self-efficacy Promotion Exercise Program will be considering to useful for various care settings to the elderly hypertensives.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.5 no.1
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• pp.45-51
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• 2012

In this paper, it's a system which recognize the user's emotions after obtaining the biological informations(pulse sensor, blood pressure sensor, blood sugar sensor etc.) about user's bio informations through wireless sensors in accordance of previously collected informations about user's stress index and classification the Colors & Music. This system collects the inputs, saves in the database and finally, classifies emotions according to the stress quotient by using multiple SVM(Support Vector Machine) algorithm. The experiment of multiple SVM algorithm was conducted by using 2,000 data sets. The experiment has approximately 87.7% accuracy.

• Journal of agricultural medicine and community health
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• v.36 no.4
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• pp.264-279
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• 2011

Objectives: The aims of this study were to evaluate the effect of a metabolic syndrome management program on participants enrolled in a public health center program in, Seoul, Korea for 6 months and to analyze the changes in their life habits and risk factors for treating their metabolic syndrome. Methods: Participants enrolled in a metabolic syndrome program at a public health center and answered questionnaires. Their waist circumference and, blood pressure were measured and their blood was tested. Based on the results, the participants were classified into 3 groups. Then, the center provided a metabolic syndrome management intervention program for the individual groups and analyzed the changes in participants' life habits and risk factors after 6 months. Results: After the intervention, the active group, showed improved physical activity, increased eating habits by 0.7 points, and decreased drinking and smoking; however, these results were not statistically significant. As for the Participants' overall health status, all groups positively changed a statistically significant result. In regard to the change in risk factors for metabolic syndrome in the active group, systolic and diastolic blood pressure and triglyceride levels were, statistically significantly decreased, meanwhile, an increase was found in HDL cholesterol level, waist measurement, and anteprandial glucose level; but the result were not statistically significant. Their review rate was 19.0%; 29.4% in the active group, 19.0% in motivating group A, and 14.5% in motivating group B. Conclusions: Participants showed changes in some life habits and risk factors, a result still far from the program's goal to improve residents' health status (improved living habits and variations in risk factors); thus, it is necessary to supplement this program for better performance.