• Title/Summary/Keyword: 수명 연장

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Antitumor and Immuno-potentiating Activity against Mouse Sarcoma 180 by Crude Polysaccharides Extracted from Fruiting Body of Tricholoma matsutake (송이(Tricholoma matsutake)의 자실체에서 추출한 조다당류가 생쥐의 Sarcoma 180에 미치는 항암 및 면역증강 작용)

  • Hur, Hyun;Choi, Yon-Il;Lee, Tae-Soo
    • Journal of Life Science
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    • v.18 no.9
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    • pp.1290-1298
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    • 2008
  • Tricholoma matsutake, one of edible and medicinal mushroom belonging to Tricholomaceae of Agaricales, has been known to contain some curing effect on gastric cancer and ulcer, and inhibitory effect on sarcoma 180 and Ehrlich sarcoma. Neutral salt soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr. NaCl, Fr. HW and Fr. MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests, crude polysaccharides were not cytotoxic against cancer cell lines such as Sarcoma 180, HepG2, HT29 and NIH3T3 at the concentration of 2.0 mg/ml. Intraperitoneal injection with crude polysaccharides showed life prolongation effect of 23.4$\sim$37.2% in mice previously inoculated with Sarcoma 180. Fr. MeOH and Fr. HW exhibited the immuno-potentiating activity of B lymphocyte by increasing the alkaline phosphatase activity by 2.2$\sim$11.9 folds compared with control at the concentration of 0.2$\sim$0.5 mg/ml. In case of Fr. NaCl, the numbers of peritoneal exudate cells and circulating leukocytes were increased by 6.0 and 1.5 folds at the concentration of 50 mg/kg, respectively. Therefore, it is concluded that crude polysaccharides extracted from fruiting body of Tricholoma matsutake showed antitumor and immuno-potentiating activity against Sarcoma 180 of mouse.

Study on Strawberry 'Maehyang' Qualities Packed with MA film of Different Oxygen Transmission Rate during Simulated Export Distribution Conditions (산소투과도를 달리한 MA 필름으로 포장한 딸기 '매향'의 모의 수출 조건에서 품질 고찰)

  • Yoon, Hyuk Sung;Choi, In-Lee;Han, Su Jung;Kim, Ju Young;Choi, Ga Eun;Yoon, Jae Su;Kang, Ho-Min
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.23 no.2
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    • pp.83-87
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    • 2017
  • This study was conducted to determine types of oxygen transmission rate (OTR) films suitable for modified atmosphere (MA) storage treatment of strawberries (cv. 'Maehyang') for export and examination related changes in quality of strawberries during simulated shipping distribution conditions ($2^{\circ}C$ for $10days{\sim}8^{\circ}C$ for 11 days). Strawberries were packed by 1,300, 10,000, 20,000, and $30,000cc/m^2{\cdot}day{\cdot}atm$ OTR films for MA storage treatment and perforated film as the control for MAP. Fresh weight loss rate was less than 0.5% in OTR films except for the perforated film. Carbon dioxide and oxygen content in packages prevailed in permissible range for strawberries under recommended CA/MA conditions (i.e., $CO_2$: 15~20%, $O_2$: 5~10%) at 10,000 cc, 20,000 cc, and 30,000 cc OTR films. Ethylene content in OTR films did not reveal significant differences during storage. The 1,300 cc OTR film revealed highest off-flavor and lowest fungal incidence rate by sensory evaluation. The firmness, soluble solids, and visual quality were preserved the highest at 10,000 cc OTR film. In conclusion, 10,000 cc OTR film preserved the highest quality and extended shelf-life by 13 days if compared with conventional distribution conditions.

A Non-Equal Region Split Method for Data-Centric Storage in Sensor Networks (데이타 중심 저장 방식의 센서 네트워크를 위한 비균등 영역 분할 기법)

  • Kang, Hong-Koo;Jeon, Sang-Hun;Hong, Dong-Suk;Han, Ki-Joon
    • Journal of Korea Spatial Information System Society
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    • v.8 no.3
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    • pp.105-115
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    • 2006
  • A sensor network which uses DCS(Data-Centric Storage) stores the same data into the same sensor node. Thus it has a hot spot problem when the sensor network grows and the same data arise frequently. In the past researches of the sensor network using DCS, the hot spot problem caused by growing the sensor network was ignored because they only concentrated on managing stored sensor data efficiently. In this paper, we proposed a non-equal region split method that supports efficient scalability on storing multi-dimensional sensor data. This method can reduce the storing cost, as the sensor network is growing, by dividing whole space into regions which have the same number of sensor nodes according to the distribution of sensor nodes, and storing and managing sensor data within each region. Moreover, this method can distribute the energy consumption of sensor nodes by increasing the number of regions according to the size of the sensor network, the number of sensor nodes within the sensor network, and the quantity of sensor data. Therefore it can help to increase the life time and the scalability of the sensor network.

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Relationship between Tensile Characteristics and Fatigue Failure by Folding or Bending in Cu Foil on Flexible Substrate (유연성 기판에 사용되는 전해 동박의 절곡 및 굴곡 피로 파괴와 인장 특성과의 관계)

  • Kim, Byoung-Joon;Jeong, Myeong-Hyeok;Hwang, Sung-Hwan;Lee, Ho-Young;Lee, Sung-Won;Cbun, Ki-Do;Park, Young-Bae;Joo, Young-Cbang
    • Journal of the Microelectronics and Packaging Society
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    • v.18 no.1
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    • pp.55-59
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    • 2011
  • Folding endurance, bending fatigue and monotonic tensile tests of 4 kinds of Cu foil on flexible substrate was performed to investigate the relationship between folding or bending endurances and tensile characteristics. The repeated 5.3 or 2.0% strain was applied to Cu foil in folding endurance test or bending fatigue test while monitoring the electrical resistance. Elastic modulus, yield strength, ultimate tensile strength, ductility, and toughness were obtained by monotonic tensile test on the same samples. The Cu foil with higher toughness and ductility showed higher reliabilities in folding or bending fatigue. However, elastic modulus and yield strength did not show any relationship with folding and bending reliability. This is because the failures of Cu foil by folding or bending fatigue were closely related to the fracture energy of metal.

Clinicopathologic Characteristics and the Prognosis of Gastric Cancer Patients at Both Extremes of Age (양극 연령층 위암 환자의 임상병리학적 특성 및 예후)

  • Song, Rack-Jong;Kim, Sun-Pil;Min, Young-Don
    • Journal of Gastric Cancer
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    • v.7 no.2
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    • pp.67-73
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    • 2007
  • Purpose: There have been several comparative studies that have focused on elderly groups of patients with gastric cancer. However, new criteria are needed for this elderly group because of the longer life span of Korean people. The diagnosis of gastric cancer has sometimes been missed in the young age group. The perioperative risk is high in the elderly age group because of their combined diseases. This study was designed to determine the differences of the clinicopathologic features and the prognosis between young and elderly patients with gastric cancer. Materials and Methods: Eighty patients were divided in two groups and these patients were selected for making comparison between young and elderly groups of patients with gastric cancer. The young age group consisted of 31 patients who were aged 35 years old or less. The elderly age group was made up of 49 patients who were aged 75 years old or above. Results: For the clinicopathologic features, the young age group was characterized by a high incidence of the poorly differentiated type of adenocarcinoma and the diffuse type too, according to the Lauren classification. On the other hand, the elderly group was characterized by a high incidence of poorly to moderate differentiated adenocarcinoma and also the intestinal type according to the Lauren classification. The other clinical differences were unremarkable. Additionally, there was no survival advantage in the young age group compared to the elderly group. Conclusion: There were no clinicopathologic and prognostic differences between both extreme age groups. So, active surgical treatment is recommended even for the elderly patients group.

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Mission Analysis Involving Hall Thruster for On-Orbit Servicing (궤도상 유지보수를 위한 홀추력기 임무해석)

  • Kwon, Kybeom
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.10
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    • pp.791-799
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    • 2020
  • Launched in October 2019, Northrop Grumman's MEV-1 was the world's first unmanned mission demonstrating the practical feasibility of on-orbit servicing. Although the concept of on-orbit servicing was proposed several decades ago, it has been developed to various mission concepts providing services such as orbit change, station keeping, propellant and equipment supply, upgrade, repair, on-orbit assembly and production, and space debris removal. The historical success of MEV-1 is expected to expand the market of on-orbit servicing for government agencies and commercial sectors worldwide. The on-orbit servicing essentially requires the utilization of a highly propellant efficient electric propulsion system due to the nature of the mission. In this study, the space mission analysis for a simple on-orbit mission involving Hall thruster is conducted, which is life extension mission for geostationary orbit satellites. In order to analyze the mission, design space exploration for various Hall thruster design variable combinations is performed. The values of design variables and operational parameters of Hall thruster suitable for the mission are proposed through design space analysis and optimization, and mission performance is derived. In addition, the direction of further improvement for the current on-orbit mission analysis process and space mission analysis involving Hall thruster is reviewed.

The Effects of Oriental Herbal Tea on the Physiological Function and Behavioral Change of Elders at Geriatric Facility (한방차가 시설노인의 생리적 기능과 행동변화에 미치는 영향)

  • Kim, Soo-Kyung;Lee, Jung-Eun;Youn, Mee-Kyung;Ko, Hee-Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.3
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    • pp.1448-1457
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    • 2014
  • Geriatric illness is increasing with aged population ratio due to a prolonged average life span. Research studies with therapeutic approach using oriental herbs have been attempted, but the very few studies of oriental herbal tea as a healthy drink have done as a health care. This study was performed to identify the effects of oriental herbal tea on the physiological function and behavioral change of elders at geriatric facility. A quasi-experimental design using a nonequivalent control group, pre-post test was used. Total 38 of elderly population (20 of experimental group and 18 of control group) was recruited. 100mL of a type of oriental herbal tea developed for this study was given to each subject 3 times a day for 30 days (from May to June 2013). The health scan analyzer and questionnaire for behavioral change were used to measure dependent variables. The data was analyzed by SPSS/WIN 18.0. After drinking the oriental herbal tea, more significant improvement on blood circulation (t=-4.466, p<.001), liver function (t=-2.855, p=.007), brain function (t=-2.545, p=.015), bone density (t=-6.125, p<.001), blood sugar (t=-4.180, p=<.001) and emotional factor (t=2.389, p=.023) as the sub-variable of behavioral change were found in the experimental group than control group. This study shows that oriental herbal tea can be effective on the physiological function and emotional relief of the elders. Therefore the tea can be utilized as an effective intervention for the health of elders in geriatric facility.

A Development of Food Preservative with the Waste of Crab Processing (게 가공폐기물을 이용한 식품보존료의 개발에 관한 연구)

  • CHANG Dong-Suck;CHO Hak-Rae;GOO Hyo-Young;CHOE Wi-Kung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.22 no.2
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    • pp.70-78
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    • 1989
  • This experiment was carried out to develop the preparation method of chitosan which has strong antimicrobial activity, and also tried to investigate as a natural food preservative with this chitosan. The antimicrobial activity of chitosan was the strongest when deacetylation of chitin was conducted at $146^{\circ}C$ for 8 hours with $50\%$ sodium hydroxide. The growth of Escherichia coil was completely inhibited by adding this low molecular weight chitosan (M. W, 35,000) at the level of concentration of 75ppm to the medium. The antimicrobial activity was strong enough against such Gram positive bacteria as Staphylococcus sp. and Bacillus sp.. The growth of these strains was inhibited by the concentration of 50ppm but it was varied in its kinds against Gram negative bacteria. The concentration of chitosan re-quired for growth inhibition of microorganisms was 100ppm against Pseudomonas sp. and Vibrio sp., 2,000ppm against Salmonella sp.. The growth of Saccharomyces sp. was inhibited by the concentration of 100ppm, but Hansenula sp., Aspergillus sp., Penicillium sp. and Mu-cor sp. did not inhibited by even more than the concentration of 5,000ppm. The shelf life of Mulkimchi (pickle type Kimchi), containing $0.2\%$ chitosan was 10 days longer than control stored at $5^{\circ}C$.

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A study for Secure the Reliability of Automated Guided Vehicle Remote Control System (무인운반차 RCS(Remote Control System)의 신뢰확보를 위한 연구)

  • Jeon, Hyong-Mo;Kang, Sang-Won
    • Journal of Digital Convergence
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    • v.15 no.5
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    • pp.207-215
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    • 2017
  • With rapid development of IT technology and biotechnology, human lifespan is extended rapidly, and we are living in the era where aging becomes the social issue. Due to this aging problem, manpower is mainly replaced by Automated Guided Vehicles (AGV) in manufacturing factories or warehouse logistics transportation. Rate of AGV use increases sharply every year. AGVs, which were used only in Smart Factories, extends its usage into indoor and outdoor operation by changing their usages to container transportation that can carry huge containers in the harbor. With the expansion of AGVs usage, the importance of RCS (Remote Control System) is also increased. In this study, we surveyed and analyzed the characteristics and technology trends of technical features of AGV's RCS that are developing in various ways to establish quality evaluation system of AGV RCS. Based on this, and by referring to international quality assessment standards, ISO/IEC 25000 series, we derived evaluation items on functional suitability and usability to secure reliability of AGV RCS. Also, it is our intention to develop evaluation model using those derived usability and reliability evaluation items.

Study on the energy-saving constant temperature and humidity machine operating characteristics (에너지 절감형 항온항습기 운전 특성에 관한 연구)

  • Cha, Insu;Ha, Minho;Jung, Gyeonghwan
    • Journal of Energy Engineering
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    • v.25 no.3
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    • pp.27-33
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    • 2016
  • The heat recovery system that was applied in this study, is the energy-saving type that can produce the maximum cooling capacity less power in use. In order to have a more precise control function the temperature and humidity of the constant temperature and humidity machine, control algorithm is applied to designed a fuzzy PID controller, and the outside air compensation device (air-cooled) demonstrated excellent ability to dehumidify the moisture, $-20^{\circ}C$ in winter. High efficiency and the low-noise type sirocco fan operate quitely and designed to fit the bottom-up and top-down in accordance with the characteristics of equipment. as a result of experiment data, the conversion efficiency is 95% or more, power recovery time is within 5sec, stop delay time is within 30sec, pump down time is 10sec, pump delay time is 5sec, heating delay time is 5sec, temperature deviation is ${\pm}2^{\circ}C$ (cooling deviation: $2^{\circ}C$, Heating deviation : $2^{\circ}C$), humidity deviation is a ${\pm}5%$ (humidification deviation 3.0%, dehumidification deviation 3.0%). Recently, ubiquitous technology is important. so, the constant temperature and humidity machine designed to be able to remotely control to via the mobile phone, and more scalable to support MMI software and automatic interface. Further, the life of the parts and equipment is extended by the failure.