• Sleep Medicine and Psychophysiology
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• v.2 no.1
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• pp.73-81
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• 1995

Objective : Patients with sleep apnea should be diagnosed with polysomnography(PSG). However, it is not easy to recommend PSG for all patients suspected with sleep apnea in practice. Therefore, we tried to develop the screening test for referral of PSG. Method : 140 patients with snoring and sleep apnea syndrome were studied by the PSG. Sleep apnea questionnaire. Zung's scale for depression. Stanford Sleepiness Scale(SSS), insomnia scale and neuropsychological test were administered. Also, blood pressure, height, weight and neck circumference were measured and some histories were taken. Correlations between respiratory disturbance index(RDI) and various parameters mentioned above and discriminant coefficients of the parameters to RDI were computed. And, we investigated sensitivities of screening tests for selection of the patients with RDI above 20. Results : Using six parameters(neck circumference, systolic blood pressure before sleep, degree of alcohol drinking, frequency of breath-holding during sleep, degree of dry mouth during sleep, sleep apnea score), the patients with RDI above 20 could be discriminated in 92.8% sensitivity. In case of more than two among six parameters(neck circumference of above 40cm, systolic blood pressure of above 125mmHg, frequent alcohol drinking, frequent breath-holding during sleep, frequent dry mouth during sleep, sleep apnea score of above 35), same patients could be discriminated in 87.6% sensitivity. And, in case of more than one among four parameters(neck circumference of above 40cm. systolic blood pressure of above 125mmHg, frequent alcohol drinking, body weight of above 80kg), discrimination sensitivity was 83.5%. Conclusions : Patients with RDI above 20 could be discriminated by above parameters with high sensitivity. Therefore, the screening test using above parameters can be applied in selection of the patients with sleep apnea for PSG in practice.

• Sleep Medicine and Psychophysiology
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• v.11 no.1
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• pp.37-43
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• 2004

Objective: The purpose of this paper is to study the possible differences in clinical and polysomnographic findings, depending on the presence or absence of subjective complaints of abnormal sleep behavior, in patients with RWA on polysomnography. Method: We reviewed patient records and polysomnographic data of patients referred to the Sleep Laboratory at Seoul National University Hospital from June 1996 through October 2002. We defined the manifest RBD group (n=32) as patients having both complaints of abnormal sleep behavior and RWA on polysomnography. The latent RBD group (n=20) consisted of patients who exhibited RWA on polysomnography but did not complain of abnormal sleep behavior. The clinical characteristics and polysomnographic findings between the two groups were compared and analyzed. Results: Fifty-two subjects had RWA, as detected by polysomnography (42 males and 10 females, mean age of $55.1{\pm}19.1\;years$). Subjects in the manifest RBD group were significantly older than those in the latent RBD group ($61.59{\pm}13.5$ vs. $44.70{\pm}2.76\;years$, independent t-test, p<0.01). More subjects in the manifest RBD group exhibited abnormal REM behavior on polysomnography than did subjects in the latent RBD group (81.3 vs. 50.0%, Fisher's exact test, p<0.05). No significant differences between the groups were found in the prevalence of brain disorders and primary sleep disorders, gender proportion, and sleep architecture. Conclusion: No difference in sleep architecture was found between the manifest and the latent RBD groups. Only age and the presence of abnormal sleep behavior on polysomnography differentiated the two groups. We suggest that RWA on polysomnography without complaints of abnormal sleep behavior may be early manifestation of manifest RBD. Attention to RWA on polysomnography is necessary to help prevent full-blown RBD from developing.

• Sleep Medicine and Psychophysiology
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• v.19 no.1
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• pp.22-26
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• 2012

Objectives: The percentage of positional sleep apnea in obstructive sleep apnea (OSA) varies in different reports from 9% to 60%. If there is a positional dependency in patients with OSA, positional therapy alone could be successful in treating about 50% of all OSA cases. The aim of this report is to compare anthropomorphic and polysomnographic data between the positional sleep apnea group and non-positional sleep apnea group with OSA whose conditions were diagnosed in our sleep clinic. Methods: This is a retrospective study of anthropomorphic and polysomnographic data of patients with OSA who was performed a nocturnal polysomnography. Positional sleep apnea was defined as having a supine apnea-hypopnea index (AHI) of twice or more compared to the AHI in the non-supine position. The patients were divided in the positional sleep apnea group and the non-positional sleep apnea group. Results: In 101 patients with OSA, 81 were male, and the mean age was $49.2{\pm}11.9$ years. Seventy-six (75.2%) were diagnosed as the positional sleep apnea. Waist to hip ratio and body mass index (BMI) were significantly higher in non-positional sleep apnea group. The frequency of severe OSA was significantly higher in this group. In the positional sleep apnea group, nocturnal sleep quality was better preserved, and consequently these patients were less sleepy during daytime. AHI was significantly lower and minimal arterial oxygen saturation during sleep was significantly higher in this group. Conclusion: The percentage of positional sleep apnea in OSA was 75.2%. AHI, BMI, and waist to hip ratio were lower in the positional sleep apnea group. These patients have less severe breathing abnormalities than the non-positional sleep apnea group in polysomnography.

• Journal of Korean Medical classics
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• v.19 no.2 s.33
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• pp.305-309
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• 2006

본 논문은 고금(古今)의 명의(名醫)들이 수면(睡眼) 이상에 대해 진행한 치료에 대해 조사함으로써, 수면(睡眼)과 오장(五臟)과의 관계에 대해 고찰하려 하였고, 임상 의안(醫案)의 관점에서 현대의 의학통계학을 이용하여 고금(古今)의 명의(名醫)들 중에서 부합 되는 조건의 질병의 의안(醫案)에 대해 약물의 귀경(歸經)을 통계를 내어, 각종 수면(睡眼) 이상에 사용한 약물 중에 어떤 한 가지 증상을 치료함에 있어서 어떤 한 가지 장부(臟腑) 계통에 응하는 특정한 규칙이 있는지 없는지를 분석하였다. 그 결과 임상에서 불면(不眼) 등의 증상을 치료할 때 사용하는 약물 중에 모두 비위(脾胃) 계통, 심(心) 계통에서 빈도수가 가장 높아서 1, 2위를 차지하였고 , 간(肝)은 3위를 차지하였고 , 또한 그 다음의 4, 5 위의 폐(肺), 신(腎)과 비교하여 현격한 차이를 보였는데 , 불면(不眼)은 간(肝)과 더욱 밀접한 관계가 있음을 알게 되었으며 , 이에 수면(睡眼)은 비위(脾胃), 심(心), 간(肝)과 밀접한 관계가 있다.

• 건강소식
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• v.24 no.4 s.257
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• pp.11-11
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• 2000

수면은 우리 삶의 많은 부분을 차지하는 중요한 삶의 영역이다. 그러나 여러 가지 원인으로 인하여 많은 현대인들이 수면의 즐거움을 제대로 누리지 못하고 있다. 미국의 경우 수면 장애에 의한 졸리움증으로 생기는 사회적ㆍ개인적 손실의 규모를 연간 약 150억 달러로 추정하고 있을 정도다. 우리나라 성인 중에 수면 장애의 하나인 불면증을 경험한 사람의 비율은 73.4%나 될 정도로 광범위하게 나타나고 있지만 정작 그 해결책을 찾지 못하고 있는 실정이다. 수면장애에는 크게 불면증을 보이는 수면 장애, 낮에 과도한 졸리움을 일으키는 수면 장애, 자다가 이상한 행동을 보이는 수면 장애로 구분되어지는데 우리가 일상에서 인식하는 수면 장애는 불면증 정도로 그치는 것이 일반적이다. 더욱이 이러한 수면 장애를 해결하는 방법의 이해 부족으로 수면제나 담배, 술 등에 의존하기 쉽고 단순히 잠을 자야 한다는 강박관념에 시달려 오히려 증상을 악화시키는 경우가 많다. 그러나 수면 장애를 올바르게 이해하고 있다면 그 해결 방안은 의외로 간단하다. 우리의 몸속에 있는 생체 시계의 주기를 규칙적으로 맞추어 가는 것이 중요하다. 또한 수면은 신체적인 요소보다는 정신적인 요소가 많이 작용하기 때문에 무엇보다도 편안한 마음가짐과 무의식적인 수면 유도가 필요하다. ('이달의 건강길라잡이'에 관한 자세한 내용은 건강길라잡이 홈페이지(http://healthguide.hihasa.re.kr)에 있습니다.)

• Sleep Medicine and Psychophysiology
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• v.18 no.1
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• pp.23-28
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• 2011

Objectives: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. Methods: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. Results: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. Conclusions: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.

• Sleep Medicine and Psychophysiology
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• v.11 no.2
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• pp.80-83
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• 2004

Objectives: The multiple sleep latency test (MSLT) is commonly used as a valid objective measure of sleepiness. The procedure of MSLT is well standardized but the sleep onset criterion is somewhat variable. One epoch of stage 1 sleep is the most commonly used criterion, and the criterion of three epochs of stage 1 sleep is also used. The purpose of this study was to compare the two criteria used to determine sleep onset. Methods: We retrospectively analyzed 60 consecutive MSLT that were performed according to a standaridized protocol. We scored each test using the two different criteria for sleep onset and then statistically analyed the results. Results: Using the different criteria, 20 patients among 60 showed changes in mean sleep latency (33.3%). The extent of change ranged from 1.3% to 38.5% (mean 15.9%). Non-narcoleptic patients showed a significantly higher incidence of change than other sleep disorder patients. Conclusion: Changes in mean sleep latency occurred according to the different criteria of sleep onset. But the difference arising from different criteria was statistically not significant in patients with moderate to severe sleepiness. Considering that 1 epoch criterion for sleep onset is more sensitive in detecting clinically significant sleepiness, the authors suggest that the 1 epoch criterion is more reliable than the 3 epochs criterion.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.681-683
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• 2022

본 연구는 수면의 질, 우울, 불안, 인지기능을 확인하고 이들의 상관관계를 알아보는 서술적 상관관계연구 연구이다. K도 G시, D시에 위치한 10곳의 경로당에서 65세 이상 일반노인 130명을 대상으로 설문조사를 통해 자료를 수집하였다. 수집된 자료는 SPSS WIN 20.0 프로그램을 이용하여 대상자의 일반적 특성의 빈도, 백분율을 산출하였고 대상자의 수면의 질, 불안, 우울, 인지정도의 평균, 표준 편차을 산출하였으며, 대상자의 일반적 특성에 따른 수면의 질, 불안, 우울, 인지정도를 t-test와 one-way ANOVA로 분석하였으며, 대상자의 수면의 질, 불안, 우울, 인지정도의 상관관계 검정은 Pearson's correlation coefficient를 실시하였다. 연구결과는 수면의 질, 불안, 우울, 인지기능의 상관관계는 불안과 수면의 질(p=-.422), 우울과 수면의 질(p=-.552)간에 유의한 음의 상관관계가 있는 것으로 나타났고, 불안과 우울은 유의한 양의 상관관계가 있는 것으로 나타났다. 노인이 지각하는 수면의 질과 우울, 불안, 인지기능의 정도를 파악하고 노인수면증진을 위한 간호중재 개발에 기초자료가 될 수 있을 것이다.

• Sleep Medicine and Psychophysiology
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• v.10 no.2
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• pp.93-99
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• 2003

Objectives：Sleep loss and excessive daytime sleepiness may have serious consequences, including traffic and industrial accidents, decreased productivity, learning disabilities and interpersonal problems. Yet despite these adverse effects, there are few epidemiological studies on sleep loss and daytime sleepiness in the general population of Korea. This study investigates the number of people who suffer from sleep insufficiency, how much recovery sleep occurs on weekends, and the relationship between the amount of recovery sleep and daytime sleepiness. Methods：A total 164 volunteers, aged 20 and over, were recruited by advertisement. The subjects were workers and college students living in Seoul, Korea. Subjects were excluded if they were aged over 60；if they had medical, neurological, psychiatric or sleep disorders that could cause insomnia or daytime sleepiness；if they were not following a regular sleep schedule；if they traveled abroad during the study；or if they did not leave home to work or were shift workers. They were interviewed and given a sleep log to complete on each of 14 consecutive mornings. They also completed the Epworth Sleepiness Scale (ESS) at noontime on the last day of the second week. All statistical data were analyzed by t-test, $X^2$-test or ANOVA, using SPSS/PC+. Results：The results showed that the subjects woke up at 6：50 (${\pm}1$：16) on weekdays, 7：09 (${\pm}1$：29) on Saturdays, and 8：12 (${\pm}1$：39) on Sundays and holidays. They took more frequent and longer naps on Sundays than on weekdays and Saturdays. The mean sleep duration was 6h 35 min. on week nights, with a mean increase of about 1h on weekends. Only 9.1% of the subjects spent more than 8h in bed on week nights, with 67% spending less than 7h, and 49.4% reported recovery sleep of more than 1h on Sundays. The subjects who reported recovery sleep of more than 2h on Sundays, showed significantly more excessive daytime sleepiness than those who reported less than 30 min (F=2.62, p<.05). Conclusions：These findings suggest that sleep insufficiency and excessive daytime sleepiness are relatively common in Korea, and that the people who get insufficient sleep on weekdays try to compensate for sleep loss with oversleeping and daytime napping on Sundays and holidays. It appeared that daily sleep insufficiency had a cumulative effect and increased daytime sleepiness.

• Journal of Oral Medicine and Pain
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• v.33 no.2
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• pp.205-218
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• 2008

Interaction between pain and sleep has long been proved through many researches, and various studies are being conducted to identify its mechanism. However, these studies have targeted on patients with systemic disease, such as rheumatic disease and fibromyalgia. There are few researches on patients with orofacial pain including temporomandibular disorder(TMD). In this study, we studied interaction between pain aspect and sleep quality in 229 patients with TMD, who visited the TMJ and Orofacial pain clinic. Pittsburgh Sleep Quality Index(PSQI), Epworth sleepiness scale(ESS) questionnaire were surveyed and sleep-screening device was operated. PSQI showed that sleep quality in TMD patients with pain was poorer than that in TMD patients without pain. The ratio of poor sleeper was higher in TMD patients with pain. Especially, TMD patients with chronic pain showed obviously poorer sleep quality than TMD patients with acute pain. The result of ESS showed that patients with painful TMD showed more daytime sleepiness than painless TMD patients. The ratio of TMD patients with chronic pain who had daytime sleepiness was higher than TMD patients with acute pain, and the amount of daytime sleepiness was higher in the group of chronic pain. In TMD patients with chronic pain, only the poor sleeper(PSQI>5) presented mean ESS>10(diagnostic criteria of daytime sleepiness). There was no correlation between pain intensity and sleep quality or daytime sleepiness. The result of ApnealinkTM for screening of sleep related breathing disorder showed that only 1 patient presented AHI>5 among 19 participants. TMD patients with chronic pain presented poor sleep quality and excessive daytime sleepiness similar to other chronic pain patients. Evaluation of sleep state by questionnaire might be useful for diagnosis and management of TMD, because sleep disturbance decreases pain threshold and pain disturbs sleep. In addition, sleep-screening device would be useful for screening sleep related breathing disorder in dental clinic.