• Title/Summary/Keyword: 쇼크

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Treatment Guidelines of Sepsis and Septic Shock (패혈증과 패혈쇼크의 치료 지침)

  • Lee, Heung Bum;Moon, Hee
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.6
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    • pp.491-498
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    • 2009
  • Severe sepsis and septic shock are major healthcare problems with high mortality, ranging from 20% to 60%, affecting millions of individuals around the world each year. The speed and appropriateness of therapy administered in the initial hours after severe sepsis develops have an important impact on the outcome. In 2004, an international guideline that the bedside clinician could use to improve the outcomes in severe cases of sepsis and septic shock was published. Several landmark studies recently demonstrated that therapeutic strategies may reduce mortality substantially. The "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock: 2008", using a new evidence-based methodology system for assessing the quality of evidence and the strength of the recommendations, was updated. The revised version is based on an updated search into 2007. Evidenced-based recommendations regarding the acute management of sepsis and septic shock are the first step toward improving the outcomes of critically ill patients. We review the treatment guidelines of sepsis and septic shock.

Modeling of a Confinement Effect in Laser Shock Peening on Titanium Alloy (티타늄 합금에 대한 레이저 쇼크 피닝에서 컨파인먼트에 따른 피닝 효과 모델링)

  • Lee, Wooram;Kim, Joohan
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.4
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    • pp.680-685
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    • 2013
  • In this study, the effect of laser shock peening on a titanium alloy was modeled using different confinements. Both liquid and solid confinement could be applied to laser shock peening, and solid confinement provided a dry laser shock peening process, which has the advantage of a corrosion-free effect. When a different confinement was applied to laser shock peening, a different peening effect would be expected. In our study, the peening effect was numerically modeled and simulated. The main effect of different confinements was a change in the impedances required to confine a shock wave from a plasma. The impedances were assumed with respect to different materials. Johnson-Cook's plastic deformation modeling was applied to the simulation. The strains and residual stresses were calculated to evaluate the confinement effects. When solid confinement was used, the residual stress increased by 60-85%, compared to the case of liquid confinement. However, the depth of the residual stress was slightly deeper. The simulated results could be applied to estimate the peening effect when a different confinement was used in the laser shock peening process.

"On-Pump" CABG on the Beating Heart - Two case report - (심폐바이패스하의 심박동상태에서 시행한 관상동맥우회로술)

  • 신종목;김기봉
    • Journal of Chest Surgery
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    • v.32 no.5
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    • pp.480-483
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    • 1999
  • The widely accepted method for coronary artery bypass grafting(CABG) is performing the distal coronary artery anastomoses on the flaccid and nonbeating heart with the aid of cardiopulmonary bypass(CPB) and cardioplegic arrest. However, current cardioplegic techniques are not consistent in avoiding myocardial ischemic damages especially in high risk patients undergoing CABG. In this regard, "Off-Pump" seems to be an ideal method for preventing myocardial ischemic damage and adverse effects during CPB. However, "Off-pump" CABG is not always technically feasible. We report 2 cases of "On-pump" CABG performed on the beating heart in high risk patients; The first patient had left ventricular dysfunction(Ejection Fraction=25%), and the second patient had cardiogenic shock after percutaneous transluminal coronary angioplasty.

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Development of a High Strength Manufacturing Technology for the Shock Absorber Base Assembly Using Friction Welding (마찰용접을 이용한 고강도 쇼크업소버 베이스 어셈블리의 제조 기술 개발)

  • Chung, Ho-Yeon
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.34 no.1
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    • pp.90-96
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    • 2011
  • The shock absorber base assembly is one of the parts in the shock absorber equipment that controls the vehicle movement. It absorbs the shock and vibration to guarantee riding stability and comfort. It demands strength, reliability and strict airtightness of the welded section because the shock absorber base assembly is a container which resists pressure and needs durability by being filled with gas and oil. However, the current engineering needs a lot of production time, has a high cost and shows a low production rate. These problem due to the eight production processes, four of which are spot welding, reinforcement welding like metal active welding (MAG), prior process of the base assembly cap and tube for precision and pressing. We will analyze the manufacturing processes of the base assembly and suggest an improved manufacturing method that uses frictional welding. The results will show that the new method of the frictional welding is better than the previous welding technique. Through the use of this concept of frictional welding, the welding conjunction will be strengthened, measurements will be more precise, and the cost and the number of processes will be reduced.

Efficient Image Deblurring using Edge Prediction (에지 예측을 기반으로 한 효율적인 영상 디블러링 -선명한 에지 예측을 기반으로 한 장의 영상으로부터의 모션 블러 제거-)

  • Cho, Sung-Hyun;Lee, Seung-Yong
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.27-33
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    • 2009
  • We propose an efficient method for single image motion deblurring using edge prediction. Previous methods for motion deblurring from a single image have been based on total variation or natural image statistics. In contrast, our method predicts sharp edges by applying bilateral and shock filters and manipulating image gradients directly, and estimates motion blur using the predicted sharp edges. Sharp edge prediction makes our method possible to deblur efficiently with less computation. Results show that our method can effectively and efficiently restore images degraded by large complex motion blur.

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Repair of Postinfarction Ventricular Septal Defect on a Beating Heart -One case report (심근경색 후 심실중격렬손의 심박동 상태에서의 교정술 -1예 보고-)

  • Kim, Hyuck;Lee, Hyung-Chang;Kim, Young-Hak;Chung, Won-Sang;Kim, Kyung-Soo
    • Journal of Chest Surgery
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    • v.37 no.6
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    • pp.543-545
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    • 2004
  • Postinfarction ventricular septal defect often induces cardiogenic shock and requires operative treatment early after myocardial infarction. Although the operative mortality of this disease has decreased during the past 3 decades, it is still relatively high. In this case, to prevent global myocardial ischemia, we used the technique of repair of postinfarction ventricular septal defect on a beating heart. This approach does not requir aortic cross-clamping and provides superior myocardial protection.

Evaluation of Rail Leakage Current and Potential in DC Railway (직류철도의 레일누설전류 밑 전위평가)

  • Han, Moon-Seob;Jung, Ho-Sung;Kim, Ju-Rak;Kil, Gyung-Suk
    • Journal of the Korean Society for Railway
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    • v.12 no.1
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    • pp.161-166
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    • 2009
  • DC feeding system is mainly floating but rail potential and leakage current are due to long parallelism between rails and ground, namely rail resistance and rail to ground conductance. Rail potential causes electric shock to human and rail leakage current causes electrolytic corrosion to nearby the buried metals. Therefore the design technologies to reduce, protect and monitor these effects are important in recent DC feeding system. Rail potential and leakage current are analysed based on propagation theory that is utilized. Monitoring and controlling rail leakage current is proposed in order to maintain rail resistance and rail to ground conductance.

Higenamine Reduced Mortalities in the Mouse Models of Thrombosis and Endotoxic Shock (마우스의 혈전증 및 내독소 쇼크 모델에 있어서 Higenamine에 의한 사망률 저하효과)

  • YunChoi, Hye-Sook;Kim, Moon-Hee
    • YAKHAK HOEJI
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    • v.38 no.2
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    • pp.191-196
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    • 1994
  • Higenamine is a tetrahydroisoquinoline alkaloid which was isolated as a cardiotonic principle from Aconiti tuber. 1.v. injection of higenamine was reported to increase the cardiac output and heart rate and to decrease the blood pressure and the systemic vascular resistance presumably by stimulating the adrenergic ${\beta}-receptors$. The anti-platelet and anti-thrombotic effects of higenamine were investigated in this paper. Higenamine(0.5 mg/ml) showed mild inhibitory effect against collagen induced platelet aggregation in vitro and the inhibito교 effect was increased with the pre-incubation$(5{\sim}30\;min)$ of platelet rich plasma(PRP) with higenamine. With the 30 min incubation, the platelet aggregation was almost completely inhibited. And the oral administration of higenamine$(50{\sim}200\;mg/kg)$ enhanced the survival in the mouse model of thrombosis and that of endotoxic shock. The anti-thrombotic and anti-septic effects of higenamine thus appear to be due to the ${\beta}-agonistic$ and the anti-platelet effects of this compound.

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Synthesis and Thermal Characteristics of Nano-Aluminum/Fluorinated Polyurethane Binders (나노 알루미늄/불소 함유 폴리우레탄 결합제의 합성 및 열적 특성 연구)

  • Lan, Qianqian;Kim, Jin Seuk;Kwon, Younghwan
    • Journal of the Korean Society of Propulsion Engineers
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    • v.20 no.5
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    • pp.40-50
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    • 2016
  • Energetic plasticizers containing explosophore groups such as $-NO_2$, $-ONO_2$, and $-N_3$ group are susceptible to impact, shock, heat, etc, finally deteriorating the insensitivity of PBXs. In this study, in an attempt to investigate the feasibility of replacing sensitive explosophore groups to fundamentally inactive but potentially (latent) energetic fluorine group which was known to have an exothermic thermite reaction with aluminum, nano-aluminum/fluorinated polyurethane binders were prepared by simultaneous polyurethane and catalyst-free azide-alkyne click reaction in the presence of nano-aluminum. Thermal characteristics of nano-aluminum/fluorinated polyurethane binders were monitored by using DSC with high pressure crucible pan.

Adrenal Crisis after Off-pump Coronary Artery Bypass Surgery (체외순환 없이 시행한 관상동맥 우회로 조성술 후 부신성 위기)

  • 최용선;류상완;홍성범;정명호;김상형;안병희
    • Journal of Chest Surgery
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    • v.37 no.7
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    • pp.601-605
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    • 2004
  • Addisonian crisis, also commonly referred to as adrenal crisis, occurs when the cortisol produced by the adrenal gland is insufficient to meet the body's needs. Pituitary apoplexy usually occurs as hemorrhagic and ischemic necrosis in the presence of a pre-existing pituitary adenoma, and is a rare sequela of cardiovascular surgery. Most pituitary apoplexy that happens in cardiovascular surgery has been known to be related to harmful effects of the cardiopulmonary bypass. The case presented herein illustrates occult pituitary apoplexy that occurred after off-pump coronary artery bypass grafting. In this patient, . the initial signs of addisonian crisis was similar to those of septic shock, and were overlooked. However, once recognized, they were reduced dramatically with standard stress-dose cortisone.