• Journal of Chest Surgery
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• v.30 no.6
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• pp.559-565
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• 1997

Donor airway ischemia is a significant problem after tracheal replacement with homograft or lung transplantation, Several factors such as omentopexy, heparin, PGl2 and fibroblast growth factor, have been shown to induce angiogenesis in vitro and in vivo. This study was designed to investigate whether omentopexy and basic flbroblast growth factor can enhance rabbit tracheal revascularization and epithelial regeneration, Three different experiments were performed with New Zealand white rabbit. In group I(n= 15 control group), only coNical tracheal autotransplantation was done. In group II(n= 15), cervical tracheal autotransplantation with omentopexy was done through subcutaneous route. In group III(n= 15), cervical tracheal autotransplantation was done and lug basic flbroblast growth factor was applied. After 3, 7 and 14 days, the animals were sacrificed. The extent of revascularization was investigated by means of uptake of the human serum albumin labelled with 99m technetium, and epithelial regeneration were assessed by means of light microscope. In the group investigated at day 3, there was statistically significant high tracheal revascularization in group III(p<0.05), but no difference at 7 and 14 days. And epithelial regenerations at day 3 were better in group III(p<0.05), and at day 7 in group II and III. But there was no difference at day 14. We concluded that b-FGF can enhance the revascularization and epithelial regeneration of the tracheal autograft especially in early phase.

• Journal of Veterinary Clinics
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• v.31 no.3
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• pp.170-174
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• 2014

This study evaluated the efficacy of soluble canine small intestinal submucosa gel in comparison to bovine thrombin in activating rabbit platelet rich plasma (PRP) by detecting growth factors. PRP from rabbits was activated by using soluble canine SIS gel, bovine thrombin, or both. The surface morphology of each group of samples was examined by scanning electron microscopy. The release of transforming growth factor (TGF)-${\beta}1$ from each set of samples was measured over 7 days using enzyme-linked immunosorbent assay. The PRP-canine SIS gel group exhibited the highest total amount of released TGF-${\beta}1$. However, there were no significant differences between any groups. The use of soluble type of canine SIS gel could be an effective alternative to bovine thrombin.

• Korean Journal of Microbiology
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• v.33 no.1
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• pp.7-14
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• 1997

This study was to elucidate the relation between the periodical requirement of growth factors(Yang et al., 1993) and the synthesis of RNA and protein during the germination of Streptomycn coefic%r A3(2) in mineral liquid medium(ISP-4) without addition of growth factors. As results, The germination time was about 10 hr, and meanwhile, periodical nutritional requirement was verified to be repeated with interval of 2 hr. Spore size was enlarged with time but its number was rather decreased. Spore could be deviJed into viable, dormant, and dead state. In such a germination process it was found that RNA and protein were being synthesized periodically when spores were stained with AO and INT methods and observed under the fluorescence microscope. Those syntheses were coincided with the period of nutritional requirement. Hence, it was discllssed that spore population in early germination would need amino acids related to protein synthesis.

• Investigative Magnetic Resonance Imaging
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• v.1 no.1
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• pp.125-129
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• 1997

Purpose: The aim of this study was to find correlation between the expression of epidermal growth factor receptor (EGFR) and MR findings in the brain glioma. Materials and Methods: MR features including edema, margin, necrosis, heterogeneity, hemorrhage and contrast enhancement were retrospectively analyzed with preoperative MR images in 41 patients with proven brain gliomas (8 low grade astrocytomas, 12 anaplastic astrocytomas, 21 glioblastoma multiformes). Immunohistochemical study of EGFR was done and their expressions were graded by both stained distribution and intensity. Correlation analysis between the MR features and EGFR expressions was done. Results: Peritumoral edema was correlated with both distribution (r=0.71, p=0.00) and stain intensity (r=0.69, p=0.00) of EGFR expression. Other MR features showed no statistical correlation with EGFR expression. Conclusion: MRI is useful in evaluation of brain glioma, and peritumoral edema is useful finding that suggests EGFR expression as well as malignant histopathologic grade of the tumor.

• Development and Reproduction
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• v.4 no.2
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• pp.137-145
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• 2000

The regulatory mechanisms of the initiation and the formation of ovarian follicles during fetal stage of mammals are largely unknown. In addition to the gonadotropins secreted from pituitary, various growth factors, and steroid hormones are believed to be involved in the differentiation and initiation of growth of primordial follicles consisting of primordial germ cells migrated from yolk sac and streamed cells from mesonephric somatic cells. In human, primordial follicles that have already initiated differentiation at fetal stage undergo either folliculogenesis to ovulate or atresia after growth. Some of primordial follicles remain without growth for 50 years or longer. The objective of this paper is to review the mechanism of the formation, growth arrest, and initiation of primordial follicles in human fetal and neonatal ovaries.

• Journal of the Korean Ceramic Society
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• v.37 no.10
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• pp.987-993
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• 2000

Bayer 공정은 보오크사이트로부터 수산화알루미늄을 추출시키는 가장 일반적인 방법으로서 공정 조건에 따라 수산화알루미늄의 1차입자경, 입도분포도 및 생산효율 등이 달라지게 된다. 이러한 수산화알루미늄의 특성에 영향을 미치는 석출인자로는 가성소다 농도, 석출온도, 종자투입량 및 알루미나와 가성소다 농도비 등이 있다. 본 실험에서는 이러한 각각의 인자들이 수산화알루미늄 석출시 입자성장에 미치는 영향을 연구하였다. 그 결과 입자성장에 가장 큰 영향력을 미치는 인자는 석출온도와 종자 투입량이며 A/C비 및 가성소다 농도는 큰 영향을 주지 않음을 알 수 있었다.

• 대한치주과학회:학술대회논문집
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• 1997.11a
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• pp.35-36
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• 1997

• Journal of Korean Society of Forest Science
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• v.76 no.4
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• pp.338-347
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• 1987

The research was carried out to investigate the related phenomena, the latent structures and synthetical characteristics in various growth factors of Phyllostachys bambusoides Sieb. et Zucc. growing at Damyang gun, Chollanamdo, using multivariate analysis. 1. By synthetical characteristics in canonical correlation between height-growth factor group and diameter-growth factor group, the former was determined by the culm height ($x_1$), and the latter by the. diameter of the largest internode($x_7$). And for those between quantitative growth factor group and qualitative growth factor group, the former was determined by the surface area($x_{10}$), and the latter by the diameter of the largest internode ($x_7$). 2. The ten growth factors of bamboo culm were simplified by two principal components on the basis of accumulated proportion aimed at 90%. The first principal component($Z_1$) as a "size factor" showed high correlation with growth factors except eye-height diameter($x_5$). The second principal component($Z_2$) as a "shape factor" showed high correlation only with $x_5$. 3. The bamboo culm, and the latent phenomenon between their growth factors could be determined by two common factors showing high communality(94.16%). The ten growth factors can be grouped into two attribute factors: quantity and quality. 4. The bamboo culms can be classified into five types: total, volume, shape-quality, inferior and middle.

• 대한생식의학회:학술대회논문집
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• 2004.06a
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• pp.57.2-58
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• 2004

• Radiation Oncology Journal
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• v.14 no.2
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• pp.87-93
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• 1996

Purpose : To determine the incidence and prognostic effects of EGFR over-expression in the high-grade astrocytomas. Materials and Methods : With 23 paraffin blocks of the high-grade astrocytomas (7 anaplastic astrocytomas and 16 glioblastoma multiforme), expression of EGFR were evaluated by immunohistochemical staining employing polyclonal antibody raised to short cytoplasmic domain of the molecule. Result : Two out of 7 anaplastic astrocytomas and 9 out of 16 glioblastoma multiforme patients showed overexpression of EGFR(p=0.44). Three out of 11 patients of age below 55 and 8 out of 12 patients of age over 54 showed EGFR overexpression(p=0.141). Median survival of the EGFR negative anaplastic astrocytoma patient was 37 months. Median survival of the glioblastoma multiforme Patients were 11 months in EGFR negative group and 7 months in EGFR positive group. But survival difference was not significant (p=0.17). Conclusion There was a marked trend of increasing overexpression of EGFR in older patients. But survival of the glioblastoma multiforme decreased by the overexpression of the EGFR without significant.