• Journal of Music and Human Behavior
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• v.2 no.1
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• pp.47-65
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• 2005

One of important goals for early childhood music learning program is to build a positive attitude toward music. Positive attitude toward music is a basic condition on effective music education for all ages of children including early childhood. Although scholars realize such importance of positive music attitude, much research for creating educational environment to foster a positive music attitude has not been performed. Edwin E. Gordon who found a music learning theory for early childhood emphasized the importance of enriched musical environment. Very young children should be provided best quality of music in an interactive way. Audie's important method of education is to provide young children with a variety of musical activities containing the materials in the ordinary life. Through this method, children accept music as close as friends who are always beside themselves, which naturally builds a solid foundation for audiation for children.

• Journal of Korean Society of Forest Science
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• v.65 no.1
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• pp.48-53
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• 1984

Using the Duff and Noland's method, the annual ring growth patterns of the red pine in the natural stands were examined at two locations; Seocheon, Chungnam-do where the stand had been infested with the pine needle gall midge, Thecodiplosis japonensis, during the years from 1975 to 1978, and Hongsong, Chungnam-do where had been no incidence of the insect damage. The results obtained are as follows: 1) With the normal red pine of 13 year old, the growth pattern in the oblique sequence indicates that the annual growth rates are maximum at the few terminal internodes, and decrease gradually with the downward internodes. Such characteristic of the growth pattern is not clear in the horizontal sequence of annual rings. 2) The indications of the radial growth reduction of the pine tree due to the pine gall midge infestation could be examined with any of three series at the crown level internodes; horizontal, vertical and oblique series. For the basal internodes, however, the horizontal series appeared to be inadequate for the analysis of the damage impact because it seemed to be masked by various factors other than direct effects of the damage. 3) Of the three ways of radial growth analyses, oblique sequence seems to be the most usefull, especially for the detection of the impact on growth caused by incipient or light infestation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.5
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• pp.616-621
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• 2007

In order to improve the storage stability of steamed bread, fermented pine needle extract syrup potentially with several functional properties was added in manufacturing the products at levels of 8.3, 11 and 18% based on Brix degree of the dough. The manufactured bread was stored at ambient conditions and measured for quality attributes. Dough added with the fermented pine needle extract syrup maintained its pH and water activity at levels of $5.45{\sim}5.90\;and\;0.94{\sim}0.96$, which are normally suitable for yeast fermentation and for appropriate dough hardness. Addition of the extract syrup increased the bread volume by more than 20%. The bread with higher content of the pine needle extract syrup showed slower increase of bread hardness during storage, suggesting retardation of bread retrogradation. The addition of the pine needle extract syrup in bread dough also inhibited growth of the aerobic bacteria and molds on the bread surface (by $0.8{\sim}24$ in log (CFU/g) at 4 day storage). Use of higher than 11% concentration presented initially a strong fine needle flavor to the bread, which disappeared soon after 2 days. Generally addition of the pine needle extract syrup did not give negative effects on the bread quality including sensory quality. Therefore, the addition of the needle extract syrup could contribute to improving the storage stability and extending the shelf life of the bread.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.12
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• pp.973-977
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• 2013

These studies were attempted to investigate the change of microbial community of anode of microbial fuel cell using swine wastewater in the enrichment step with the lapse of time. Microbial fuel cells enriched by a 1 : 1 mixture of anaerobic digestive juices of the sewage treatment plant and livestock wastewater. Enrichment culture step was divided into three stages to indentify the microorganisms. It was separated by each lag phase, exponential phase, and stationary phase. These steps were determined by the change of the current value. The current after enrichment was generated about $0.84{\pm}0.06mA$. We were cut out the different 17 bands in the DGGE fingerprint gel to do sequencing. The bands which the concentration was increasing or newly appearing with the lapse of time were included for this study. In the lag and exponential phase, Clostridium, Rhodocyclaceae, Bacteriodetes, and Uncultured bacterium etc. were detected. There were in the stationary phase Geobacter sp., Rhodocyclaceae, Candidatus, Nitrospira, Flavobactriaceae and uncultured bacterium etc. Geobactor among microorganisms detected in this study is known as the Electrochemically active microorganisms. It may include electrochemically active microorganisms to be considered as electrical activity microorganisms.

• Proceedings of the Technology Innovation Conference
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• 2004.06a
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• pp.3-26
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• 2004

현재 우리나라는 제조업 중심 사회에서 서비스 중심 사회로 경제구조가 변화해 가고 있다. 이에 따라 기업 성장의 원동력으로서의 기술혁신의 역할을 서비스 산업에도 적용하는 연구가 시작되고 있다. 그간 제조업에서의 기술혁신에 대한 연구는 많이 있었으나, 서비스 산업의 기술혁신에 대해서는 연구가 부족했다. 특히 서비스 산업의 개별 섹터를 심층적으로 분석한 연구도 역시 부족한 상황이다. 본 연구에서는 한국의 이동전화 서비스 산업을 중심으로 서비스 산업에서 나타나는 기술혁신의 동태성을 살펴 보았다. 기존 이동전화 서비스 산업을 다룬 연구에서는 주로 국가별 비교로서 규제나 법개정에 의한 파급효과를 관찰하는 정치적인 목적이 강했으며, 서비스 산업 관점에서 제조업의 제품혁신에 해당하는 신규 서비스 개발, 제조업의 공정혁신에 해당하는 운용기술개선의 변화를 기술혁신의 관점에서는 연구하지 않았다. 본 연구에서는 서비스 혁신을 이동전화 서비스 산업에서의 대규모 표준화된 통신 네트워크에서 고객의 요청에 의해 즉시 생산되는 무형의 산물로서 서비스 사업자의 기술개발에 의해 창출된 것으로 정의하였다. 구체적으로 고객이 제공받는 서비스 그 자체의 변화로서 새로운 기능이 추가되는 경우를 서비스 제품 혁신(Service product innovation), 고객에게 서비스를 제공하는 과정의 변화나 기능을 효율적으로 제공하는 것을 서비스 과정 혁신(Service process innovation)으로 정의하였으며 이의 변화를 통해 이동전화 서비스 산업의 기술혁신패턴 파악 및 서비스의 수명주기에 따른 혁신의 세부 형태를 살펴보고 기술혁신의 동태성을 파악하였다. 연구의 결과, 이동전화 서비스 산업에서는 기존의 제조업에서 나타나는 선 제품혁신, 후 공정혁신의 혁신패턴과는 반대로, 공정혁신이 먼저 발생한 후, 제품혁신이 나타나는 동태성을 보여주었다. 또 서비스의 수명주기에 따라 세부적인 혁신의 형태가 달라지는 모습을 확인 할 수 있었다.a}E$)는 동결건조 0.5%가 control사이에서 0.95로 가장 색차가 크게 나타났으며, 그 다음이 냉동분쇄 0.5% 0.83으로 나타나 송이의 첨가율이 높을수록 색차가 크게 나타나는 것을 알 수 있다. 색차가 가장 낮은 제품은 법동분쇄 0.3%, 동결건조 0.3%로 나타났다. 송이양갱의 색(color), 냄새(flavor), 맛(taste), 외관(appearances), 질감(viscosity), 종합적 평가(overall acceptability) 등의 관능평가를 실시한 결과 중 색에 대한 기호도는 냉동분쇄 0.1% 송이양갱이 가장 높은 것으로 나타났으나, 집단간 유의한 차이는 나타나지 않았고, 냄새는 동결건조 0.1%의 송이양갱이 3.38로 가장 점수가 높았으며, 냉동분쇄 0.3%의 송이양갱이 2.81로 가장 낮은 기호도를 나타내었다. 맛에서는 p<0.01수준에서 집단간 유의한 차이를 나타내었는데, 동결건조 0.1%가 그 중 가장 높은 기호도를 나타내었으며, 그 다음이 동결건조 0.5%였다. 가장 낮은 선호도를 나타낸 것은 열풍건조 0.5%였다. 질감은 P<.05 수준에서 집단간 유의미한 차이를 나타내었으며 동결건조 0.1%가 가장 높은 기호도를 나타내었으며, 동결건조 0.5%함유 송이양갱이 1.21로서, 현저히 낮은 기호도를 나타내었다. 종합적인 평가에서는 동결건조 0.1%함유 송이양갱이 가장 높은 기호도를 나타내었고 열풍건조 0.5% 함유 송이양갱이 가장 낮은 기호도를 나타내었다. 이상의 연구결과에서 각기 다른 전처리를 한 송이의 첨가량에 따른 송이양갱의 이화학적 특성에서는 큰 차이가 없었으나, 동결 건조한 송이를 0.15% 첨가한 송이양갱이 관능적 기호도 특성에서 가장 적당한 것으로 평가되어 실용화에는 동결건조 처리한 송이버섯을 0.1% 첨가하여 송이양갱을 제조하는 것이 가장 좋은 것으로 권장된다.ula showed a good agreement with the experimen

• Journal of Veterinary Clinics
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• v.27 no.3
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• pp.232-239
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• 2010

Two cell lines derived from spontaneous canine mammary gland tumors were established and characterized. Mammary gland tumors from 9 years old pug and 9 years old toy-poodle dogs were collected by aseptic surgical resection and primary culture was performed. The histopathologic examination of tumors revealed adenocarcinoma and complex carcinoma and two dogs died from metastasis of the tumors. The tumor cells were subcultured over 60 times for more than 1 year and morphological consistency maintained. Light microscopic examination, growth curve, doubling time calculation, xenotransplantation to female nude mice, immunohistochemistry for wide spectrum keratin, vimentin, $\alpha$-smooth muscle actin and cytokeratin 8 was performed for characterization. The cell lines exhibited polygonal, elongated cell shape and cytoplasmic bridge and doubling time of 47.1 hrs and 18.6 hrs, respectively. Subcutaneous xenotransplantation to nude mice of the cells produced localized palpable mass within 4 weeks in 4 of 5 and 5 of 5 nude mice, respectively. In immunohistochemical examination one cell line showed strong positive against wide spectrum keratin and cytokeratin 8 and the other cell line showed strong positive against smooth muscle actin and cytokeratin 8. Additional characterization would be possible by investigator's needs and the cell lines may be useful for in vivo and in vitro studies of canine mammary tumor and adjuvant therapies.

• Journal of the Korean Vacuum Society
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• v.16 no.5
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• pp.371-376
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• 2007

We have investigated the lasing characteristics of the InGaAs quantum dot laser diode (QD-LD) and InGaAs quantum well laser diode (QW-LD) operated at the 980 nm wavelength range. The 980-nm lasers are used as a pumping source for a erbium-doped fiber amplifier (EDFA) and it shows high efficiency in long-haul optical fiber network. We have compared the threshold current density, the characteristic temperature, the optical power and the internal efficiency of QD-LD and QW-LD under a pulsed current condition. The QD-LD shows superior performances to the QW-LD. Further optimization of a LD structure is expected to the superior performances of a QD-LD.

• Korean Journal of Veterinary Research
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• v.13 no.1
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• pp.85-102
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• 1973

In the event a population of animals is exposed to ionizing radiation, proper disposition of animals will minimize loss to the farmer and protect the public from unwholesome meat and dairy products. Clinical response is an important factor in considering salvage of animals for food following exposure to ionizing radiation whether the dose is lethal or not. It is the purpose of this report to present the discussions of blood picture and growth of y ung growing rabbits exposed to cobalt-60 gamma-irradiation. The experimental animals were Hyrnalayan rabbits of 65 days old. The body weight for all animals of the time of irradiation was approximately 450g. The 96 rabbits used in the experiment were allotted t groups of eight. Rabbits in one group served as controls and the others were exposed to single doses of 100, 200, 300, 400, 500, 600 and 700 Roentgens (R). The exposure does rate averaged 15 R per minute. Central blood was obtained by heart puncture. Erythrocyte and leukocyte enumerations and, determinations of hemoglobin in blood and hematocrit value were made in the usual manner. Erythrocyte counts, concentrations of hemoglobin in blood, and hematocrit readings dropped to the lowest value between 1 and 4 weeks postirradiation, returning towards the control values. But recovery was not complete at the time of the last determination on 6 weeks postirradiation. There was a progressive decrease with increasing radiation does in the above values. Mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration were not affected by the irradiation. After irradiation of each does the numbers of total leukocyte and the absolute numbers of various types of white cell began to decrease rapidly, and reached a minimum after 2 weeks, returning towards normal levels. But recovery was not complete at the time of the last determination on 6 weeks postirradiation. The reductions in total leukocyte and differential counts as the radiation does increases were apparent. Relative neutrophilia was observed in each irradiated group because of more expense of lymphocytes after irradiation. Growth rate of the rabbits was not affected by 100 R of whloe-body irradiation, while rabbits irradiated with 200, 300, 400 and 500 R showed marked depression of growth rate. As the radiation does increases, a depression of growth rate was apparent. The rabbits exposed to 600 and 700 R ceased from growing and recovery was not recognized during the experimental period.

• Journal of Life Science
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• v.25 no.1
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• pp.1-7
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• 2015

Cyclin D is a member of the cyclin protein family, which plays a critical role as a core member of the mammalian cell cycle machinery. D-type cyclins (D1, D2, and D3) bind to and activate the cyclin-dependent kinases 4 and 6, which can then phosphorylate the retinoblastoma tumor suppressor gene products. This phosphorylation in turn leads to release or derepression of E2F transcription factors that promote progression from the G1 to S phase of the cell cycle. Among the D-type cyclins, cyclin D3 encoded by the CCND3 gene is one of the least well studied. In the present study, we have investigated the biochemistry of the proteolytic mechanism that leads to loss of cyclin D3 protein. Treatment of human prostate carcinoma PC-3-M cells with lovastatin and actinomycin D resulted in a loss of cyclin D3 protein that was completely reversible by the peptide aldehyde calpain inhibitor, LLnL. Additionally, using inhibitors for various proteolytic systems, we show that degradation of cyclin D3 protein involves the $Ca^{2+}$-activated neutral protease calpain. Moreover, the half-life of cyclin D3 protein half-life increased by at least 10-fold in PC-3M cells in response to the calpain inhibitor. We have also demonstrated that the transient expression of the calpain inhibitor calpastatin increased cyclin D3 protein in serum-starved NIH 3T3 cells. These data suggested that the function of cyclin D3 is regulated by $Ca^{2+}$-dependent protease calpain.

• Journal of the Korean Magnetics Society
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• v.7 no.1
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• pp.13-18
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• 1997

The effects of the various raw material composition and sintered temperature on the physical properties of Ni-Zn ferrite have been investigated. They turned out to be spinel structure by X-ray diffraction and the size of grain from microscope was from 6 ${\mu}{\textrm}{m}$ to 16 ${\mu}{\textrm}{m}$. As the sintering temperature was increased from 1030 $^{\circ}C$ to 1070 $^{\circ}C$, the initial permeability and magnetic induction has increased and the both of Q factor and coercive force has decreased. The coercive force and curie temperature were almost the same at each specimen. Their values were about 0.20 Oe and 220 $^{\circ}C$. The frequency of specimen will used in the range from 400 kHz to 20 MHz. The basic composition of $Ni_{0.14}Zn_{0.64}Cu_{0.22}Fe_2O_4$ (specimen B) sintered at 1050 $^{\circ}C$ shows the best results at magnetic induction($B_r & B_m$).