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Correlation Between Vertebral Marrow Fat Fraction Measured Using Dixon Quantitative Chemical Shift MRI and BMD Value on Dual-energy X-ray Absorptiometry (Dixon 정량 화학적 변위 자기공명영상을 이용한 척추 골수 지방함량과 이중에너지 방사선 흡수법의 BMD 값의 비교)

  • Youn, In-Young;Lee, Hwa-Yeon;Kim, Jae-Kyun
    • Investigative Magnetic Resonance Imaging
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    • v.16 no.1
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    • pp.16-24
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    • 2012
  • Purpose : The purpose of this study was to determine whether there is a significant correlation between vertebral marrow fat fraction measured using Dixon quantitative chemical shift MRI (QCSI) and BMD on dual-energy X-ray absorptiometry (DXA). Materials and Methods: This retrospective study included 68 healthy individuals [mean age, 50.7 years; range, 25-76; male/female (M/F) = 36/32] who underwent DXA of the L-spine and whole body MRI including QCSI of the L-spine and chemical shift MRI of the liver. The enrolled individuals were divided into subgroups according to sex and T-score [i.e., normal bone density (M/F=27/23) and osteopenia (M/F=9/9)]. Vertebral marrow (Dixon QCSI, TR/TE 10.2/4.8 ms) and hepatic fat fractions (chemical shift technique, TR/TE 110/4.9 and 2.2 ms) were calculated on MRI. We evaluated whether there were significant differences in age, body mass index (BMI), vertebral marrow fat fraction, or hepatic fat fraction among the subgroups. Whether or not the participant had reached menopause was also evaluated in females. The correlations among variables (i.e., age, BMI, vertebral marrow and hepatic fat fractions, BMD) were evaluated using Spearman's correlation method. Results: There were no significant differences in age, BMI, or vertebral marrow and hepatic fat fractions between the two male subgroups (normal bone density vs. osteopenia). In female subjects, mean age in the osteopenic subgroup was greater than that in the normal subgroup (p=0.01). Presence of menopause was more common in the osteopenic subgroup [77.8% (7/9)] than the normal subgroup [26.1% (6/23), p<0.05]. The other variables showed no significant difference between female subgroups. The only significant correlation with marrow fat fraction after partial correlation analysis was that with age in the female subjects (r=0.43, p<0.05). Conclusion: The vertebral marrow fat fraction calculated using the Dixon QCSI does not precisely reflect the mild decrease in BMD for either sex.

PREDICTION OF THE SUM OF MESIODISTAL WIDTHS OF THE UNERUPTED PERMANENT CANINES AND PREMOLARS (미맹출 영구견치 및 소구치의 폭경 예측)

  • Park, Dong-Ock;Sung, Jae-Hyun
    • The korean journal of orthodontics
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    • v.18 no.2
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    • pp.407-420
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    • 1988
  • The primary objective of this study was to make the prediction percentile tabulation of the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent incisors in normal and crowding groups. Crowding group consisted of 85 pairs of dental casts (42 males and 43 females) with more than 4mm of crowding in anteriors. Normal group consisted of 109 pairs of dental casts (65 males and 44 females) with less than 1mm of spacing or crowding in anteriors. The mesiodistal crown diameters of permanent teeth were measured from the dental casts using the sliding calipers (Mitutoyo Co., Japan). From the study, the obtained results were as follows: There were not significant differences between male and female in both groups on the basis of the ratios between the sum of mesiodistal widths of incisors and the sum of mesiodistal widths of canines and premolars. There was not significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of mandibular incisors and the sum of mesiodistal widths of mandibular canines and premolars and was significant differences between two groups on the basis of the ratio between the sum of mesiodistal widths of mandibular incisors and the sum of mesiodistal widths of maxillary canines and premolars. There was significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of maxillary incisors and the sum of mesiodistal widths of mandibular canines and premolars. There was significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of maxillary incisors and the sum of mesiodistal widths of maxillary canines and premolars. The percentile prediction tabulations were made in an attempt to predict the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent mandibular incisors in each group. The percentile prediction tabulations were made in an attempt to predict the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent maxillary incisors in each group.

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The Investigation of the Wearing Spectacles Rate of Middle School Students in Jeju Islands (제주도 지역 중학생의 안경착용률 조사)

  • Kang, In-San;Choi, Ji-Young;Song, Yun-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.11 no.3
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    • pp.231-240
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    • 2006
  • This study conducts a questionnaire survey of 492 middle school students in Jeju islands about the rate of using glasses/contact lens, the place and time of visual acuity test, the period of changing the glasses, the purchase price, the mason to change the glasses, the interrelationship between wearing spectacles and residential district, etc. The results are as follows: 1. 45.33% of the object of investigation use the glasses or contact lens to correct their visual acuity. Among them, the student who wears only glasses is 93.27%, the student who wears glasses and contact lens together is 5.83%, the student who wears only contact lens is 0.90%. 2. As for the period of changing his(her) glasses, below 6 month is 20.18%, from 6 month to one year is 52.02%, from one year to two years is 20.18% and more than two years is 7.62%. 3. As for the purchase price to change his(her) glasses, below 30,000won is 13.45%, from 30,000won to 50,000won is 43.50%, from 50,000won to 70,000won is 23.77%, from 70,000won to 100,000won is 15.25% and more than 100,000won is 4.03%. 4. As for the reason of changing his(her) glasses, cause of change of visual acuity is 55.16%, by broken frame and lens is 27.35%, as want to just change his(her) spectacles is 14.80% and as the others is 2.69%. 5. As for the relative importance in purchasing glasses, the student who thinks more frame is 16.59%, the student who thinks more lens is 67% and the student who thinks both frame and lens is 58.74%. 6. As for the frist time of visual acuity test, 1 grade of elementary school is 37.2%, 3 grade of elementary school is 12.56%, 4 grade of elementary school is 11.66% and 6 grade of elementary school is 11.66%. 7. As for the place of visual acuity test to determine the Dptr. of glasses which wear now, opitican's shop is 57.85% and ophthalmic clinic is 42.15%. 8. As for the frist time of wearing the glasses or contact lens for correct his(her) visual acuity, the most of answer(21.97%) is at 6 grade of elementary school. 9. As for the reason why does not wear the glasses or contact lens though his(her) naked binocular vision is below 0.8, as does not feel any difficulty in daily life is 62.5%, as know that the more wear, the more decrease his(her) visual acuity is 15.65%, by economical circumstance is 6.24% and as not good externally is 15.63%, respectively.

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An Outbreak of Mumps in Taejon. Korea. 1998 (1998년 대전지역에서 유행한 볼거리의 임상적 연구)

  • Kang, Hee-Dong;Lee, Kyung-Yil;Cha, Sang-Won;Yoon, Kye-Nam;Lee, Dong-Joan;Han, Ji-Whan;Kang, Jin-Han;Whang, Kyung-Tai
    • Pediatric Infection and Vaccine
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    • v.6 no.2
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    • pp.239-244
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    • 1999
  • Purpose : In 1998, there was an outbreak of mumps in Taejon, Korea. We analyzed the monthly incidence, clinical manifestations, and complications during the outbreak and the annual incidence of the recent ten years. Methods : We reviewed the clinical records of 35 mumps patients who had been admitted to Taejon St. Mary's Hospital from January to December, 1998. Results : Mumps was prevalent in summer(from June to August) with 20 cases(57%). Thirthy-three patients(94.3%) received MMR at 15 months of age and no patients received a booster mumps vaccine. The mean age of the mumps patients was 10.5 years-old and the majority of mumps(71%) occurred between 5 and 12 year of age. The male female ratio was 2.2 : 1. The clinical manifestations were swelling of parotid gland(100%), fever (91%), vomiting(77%), abdominal pain(74%) and headache(66%) in order of frequency. Meningitis occurred in 20 cases(57%) and the mean WBC count of CSF was $464{\pm}263/mm^3$. In serology, the mean serum amylase level was $483{\pm}294IU/dL$ and anti-mumps IgM and IgG were positive in 11 and 15 out of 18 cases, respectively. From 1989 to 1997, the mean number of inpatients with mumps was 3.4 per year. Conclusion : We experienced an outbreak of mumps in 1998. It is suggested that there was a primary mumps vaccine failure in Korea and that further studies for vaccine faiure and method of booster mumps vaccine are necessary.

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Analyzing Career Paths and College Life Plans of Department of Chemistry Education Students in Teacher's College Examined by Their Roadmaps (사범대학 화학교육과 학생들의 로드맵을 통한 진로 목표와 대학 생활 계획 분석)

  • Park, Jongseok;Bae, Sungwoo
    • Journal of the Korean Chemical Society
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    • v.56 no.6
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    • pp.751-758
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    • 2012
  • In this study, we analyzed career paths and college life plans of department of chemistry education students in teacher's college examined by their roadmaps. We let students make their roadmaps and analyzed them using the PASW 18 program. There were significant differences on gender in their career paths, learning English, traveling and volunteer activity. Female students for passing the MEET(Medical Education Eligibility Test) or DEET(Dental Education Eligibility Test) were more interested in learning English and traveling than male students. In addition, female students were more interested in volunteer activity. And the lower year students, the more interested in medical paths, learning English, traveling, getting good grades, exchange student program and scholarship. On the other hand the higher year students, the more interested in group study or E-learning. Then significant differences were in learning English, traveling and getting good grades by students's career paths. Students who wish to pass the MEET or DEET were more interested in learning English and getting good grades. Those two factors were essential in passing the MEET or DEET. Students who did not specified their career paths had more traveling plans than other students for setting their directions of careers. These results show that freshman and female students don't recognize the identity of teacher's college correctly. Because of reduction in the number of teacher recruitment according to decrease of students by birth rate drop, students in teacher's college are expected to continue like this trend that students look for other paths. Therefore, it is required career counseling and guidance for students who give priority practical path choices and college life plans over original characteristics of teacher's college. And it should be reconsidered the direction of chemistry education prepared the identity of teacher's college reflected in this actuality.

Endovascular Repair of Acute Type B Aortic Dissection: The Early Results and Aortic Wall Changes (급성 B형 대동맥 박리의 혈관내 스텐트-그라프트 삽입이 초기성적 및 대동맥 벽의 변화)

  • Her, Keun;Won, Yong-Soon;Shin, Hwa-Kyun;Yang, Jin-Sung;Baek, Kang-Seok
    • Journal of Chest Surgery
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    • v.43 no.6
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    • pp.648-654
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    • 2010
  • Background: This study assessed the early results of endovascular repair of acute type B aortic dissection and the aortic wall changes following endovascular repair. Material and Method: From July 2008 to May 2009, the preoperative and follow-up computed tomography (CT) scans of 5 patients with acute type B aortic dissection were evaluated, and these patients had underwent stent graft implantation within 13 days of the onset of dissection (mean: 7 days; range: 3~13). The whole lumen (WL), true lumen (TL) and false lumen (FL) diameters were measured at the proximal (p), middle (m) and distal (d) third of the descending thoracic aorta. Result: The study included four men and one woman with an average age of $59.4{\pm}20.1$ years (age range: 37~79 years). The follow-up CT was performed and evaluated at 7 days and 6 months. The primary tear was completely sealed in all the patients. No paraplegia, paresis or peripheral ischemia occurred and none of the patients died. No endoleaks developed in any of the patients during follow-up. The TL diameters increased from 20.4 to 33.5 mm in the proximal third (p/3), from 19.5 to 29.8 mm in the middle third (m/3) and from 15.2 to 23.5 mm in the distal third (d/3). The FL diameters decreased from 18.7 to 0 mm in the p/3, from 15.4 to 0 mm in the m/3 and from 21.4 to 8.7 mm in the d/3. The changes in the TL diameter were statistically significant in the middle and distal aorta, and those changes in the FL diameter were not statistically significant. There was a decrease in the WL after repair, but this was not statistically Significant. In three patients, the false lumen disappeared completely on follow-up CT at 6 months. Two patients had patent false lumens and no thrombosis. Conclusion: The early results showed that endovascular repair was effective in treating acute type B aortic dissection, and endovascular repair promoted positive aortic wall changes.

Midterm Results of Aortic Valve Replacement Using Tissue Valve (조직판막을 이용한 대동맥판막치환술의 중기성적)

  • Moon, Duk-Hwan;Lee, Jae-Won;Kim, Yun-Seok;Cho, Won-Chul;Jung, Sung-Ho;Choo, Suk-Jung;Chung, Cheol-Hyun
    • Journal of Chest Surgery
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    • v.43 no.6
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    • pp.627-634
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    • 2010
  • Background: The durability of the tissue valve is important in choice between a mechanical valve and a tissue valve in cardiac surgery. We studied the mid-term results of tissue valve in the aortic position. Material and Method: The subjects were 380 patients who had undergone aortic prosthesis replacement between May 1990 and March 2009. We retrospectively analyzed hospital and outpatient records: the mean age was $69{\pm}9$ years; the male to female ratio was 227 : 162; and the mean follow-up duration was $46.7{\pm}40.8$ months (range 0~196 months). Result: 389 surgical cases in total had been taken with 380 patients. Early death occurred in 15 patients (3.9%). Overall survival rate at 1, 5 and 10 years were 92.3%, 78.1% and 54.2% respectively. Freedom from reoperation at 1, 5 and 10 years were 98.4%, 97.1% and 91.7% respectively. Freedom from structural valvular deterioration at 1, 5 and 10 years were 96.1%, 92.3% and 88.0% respectively. In the multivariate analysis of preoperative risk factors, young age (p<0.001) was significant risk factor for reoperation. High peak velocity in the postoperative period (p=0.034) and young age (p=0.029) were significant risk factors for structural valvular deterioration. Old age (p=0.001), long bypass time (p=0.035), concomitant coronary artery bypass graft surgery (p=0.003) and preoperative low left ventricular ejection fraction (p=0.003) were significant factors for early mortality. Preoperative estimated glomerular filtration rate (< 60 mL/min) (p=0.025) and persistent left ventricular hypertrophy (p=0.032) were the risk factors for late mortality. Conclusion: This study showed that the freedom from reoperation and the freedom from structural valvular deterioration in aortic tissue valve replacement were acceptable. It will be necessary to conduct further studies with long-term follow-up and more patients.

An Epidemiologic study on the Orthodontic Patients Who Visited Department of Orthodontics, Chosun University Dental Hospital Last 10 Years(1990${\sim}$1999) (최근 10년간 조선대학교 부속치과병원 교정과에 내원한 부정교합 환자에 관한 역학적 연구(1990${\sim}$1999))

  • Yoon, Young-Jooh;Kim, Kwang-Won;Hwang, Mee-Sun
    • The korean journal of orthodontics
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    • v.31 no.2 s.85
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    • pp.283-300
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    • 2001
  • With socioeconomic development and change of esthetic recognition, the demand for orthodontic treatment and number of orthodontic patients has been increasing so rapidly. And frequency of malocclusion was changed. So this study was done in an attempt to provide an epidemiologic study so that we can accomodate their orthodontic needs adequately and to obtain the reliable quantitative information regarding the characteristics of orthodontic patients. Distribution and trends were examined in 3,070 malocclusion patients who had been examined and diagnosed at Department of Orthodontics, Dental Hospital, Chosun University over 10 year-period from 1990 to 1999. The results were as follows : 1. The number of patients per year was increasing trend and higher visiting rate in female(56.5%) than in male(43.5%). 2. Age distribution had shown 7${\sim}$ 12 year-old group being the largest(37.9%) and each percentage of 13${\sim}$18, 19${\sim}$24, above-19, 0${\sim}$6 year${\sim}$old group was 32.0%, 19.6%, 7.1%, 3.4%. 3. Hellman dental age IVa which is completion of the permanent dentition showed the highest percentage in male and female. 4. Geographic distribution showed a majority of patients in Kwang Ju(71.0%). Group within the distance 10km from Chosun Dental Hospital was 56.3% and group within 20km was 14.7%. 5. Anterior cross bite showed the highest percentage in chief complaints and percentage of Mn. prognathism and protrusion of Mx. teeth was 12.6%, 12.2%. 6. Distribution in the types of malocclusion according to the Angle's classification had shown; 38.9% for Class I, 20.7% for Class II division 1, 2.0% for Class III division 2, 38.4% for Class III. 7. In the dental vertical dysplasia according to the Angle's classification, deep bite was the most frequent in Class II div.1 and div. 2(24.3%, 56.7%) and open bite in Class III(21.4%). 8. In the skeletal sagittal dysplasia, 39.3% of skeletal Class II was due to the undergrowth of the mandible and 46.3% of skeletal Class III was due to the overgrowth of the mandible. 9. Distribution in orthodontic treatment acceding to the extraction and nonextraction had shown 66.9% for nonextraction case, 33.1% for extraction case, and four first bicuspids have been extracted in the highest percentage(38.6%). 10. Patients who had orthognathic surgery comprised 7.9%, with an increasing trend.

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The Effect of Radiation Therapy on Oligodendrogliomas (회돌기교종의 방사선치료 효과)

  • Yoon Sei Chul;Kim Sung Whan;Chung Soo Mi;Gil Hok Jun;Shinn Kyung Sub;Bahk Yong Whee;Kang Joon Ki;Song Jin Un
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.47-52
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    • 1991
  • From April,1983 through April,1989, we have treated histologically proven 21 patients with oligodendroglioma using 6 MV linear accelerator at the Division of Radiation Therapy, Kangnam 51. Mary's Hospital Catholic University Medical College. These are 8% of the irradiated 246 primary brain tumors during the same period. To investigate influencing factors on the survival of irradiated U patients with oligodendroglioma, we analyzed the cerebral location of the involvements, initial symptoms, CT findings and survival rates, retrospectively. One case was lost to follow up and excluded from survival data. Of the 28 patients, thirteen were male and 8 female. Ages ranged from 5 to 68 years with a median age of 38 years. Radiation doses varied from 3900 cGy to 0480 cGy and were given for 5 to 8 weeks. All but one were supratentorial. The involvement of the frontal and parietal lobes were 10 (48%) patients in each and temporal lobe in 8 (38.1%). Histological diagnosis was made by stereotactic biopsy in 3 and postoperatively in 18. The type of surgery was divided into partial, subtotal and total resection in 7,9 and 2 cases respectively. In 6 cases, chemotherapy was also tried during or after radiation therapy. Major presenting symptoms were headache, cerebral motor, nausea & vomiting and epilepsy in 18,12, 7 and 5 respectively in decreasing order. In CT analysis, low density (02%), cystic mass (33%), calcifiestion (66%) and positive contrast enhancement (42.8%) were observed as the highest frequency. Mean survival duration after radiation therapy was 38 months (K-M methods). We could not achieve statistically significant factors influencing on the survival rate after radiation therapy for oligodendrogliomas by one or two tail test.

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A Study on Nutritional Status of the Long-lived Elderly People in Kyungnam (경남 일부지역 장수노인의 영양섭취상태에 관한 연구)

  • 최희정;김경업;김성희;강동희;정효숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.5
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    • pp.877-884
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    • 2002
  • This study was carried out to examine nutrients intake and food preference in 100 elderly people aged over 85 years residing in Namhae-gun Kyungnam. Mean daily energy intake and Korean recommended dietary allowances (RDA) percent were 1547.6$\pm$452.7 kcal and 91.5%, respectively. Mean daily intakes of protein (63.1$\pm$28.2 g), iron (16.7$\pm$11.2 mg), vitamin Bi (1.0410.4 mg) and vitamin C (97.0$\pm$45.3 mg) were higher than RDA. The intakes of calcium (418.1$\pm$189.7 mg) and vitamin B2 (0.94$\pm$0.5 mg) were shown to be 58.4% and 78.4% of the RDA. Females had higher intakes of energy and most other nutrients than males. Major food source of energy and protein intakes was rice and cereals, and that of lipid intake was meat, fish, egg and beans. Cooked rice, all kind of vegetables, fish, yogurt and sugars were preferred to the subjects. The most preferred taste was sweet.