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Interaction between Pain Aspect and Sleep Quality in Patients with Temporomandibular Disorder (측두하악장애 환자에서의 통증양상과 수면과의 관계)

  • Tae, Il-Ho;Kim, Seong-Taek;Ahn, Hyung-Joon;Kwon, Jeong-Seung;Choi, Jong-Hoon
    • Journal of Oral Medicine and Pain
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    • v.33 no.2
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    • pp.205-218
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    • 2008
  • Interaction between pain and sleep has long been proved through many researches, and various studies are being conducted to identify its mechanism. However, these studies have targeted on patients with systemic disease, such as rheumatic disease and fibromyalgia. There are few researches on patients with orofacial pain including temporomandibular disorder(TMD). In this study, we studied interaction between pain aspect and sleep quality in 229 patients with TMD, who visited the TMJ and Orofacial pain clinic. Pittsburgh Sleep Quality Index(PSQI), Epworth sleepiness scale(ESS) questionnaire were surveyed and sleep-screening device was operated. PSQI showed that sleep quality in TMD patients with pain was poorer than that in TMD patients without pain. The ratio of poor sleeper was higher in TMD patients with pain. Especially, TMD patients with chronic pain showed obviously poorer sleep quality than TMD patients with acute pain. The result of ESS showed that patients with painful TMD showed more daytime sleepiness than painless TMD patients. The ratio of TMD patients with chronic pain who had daytime sleepiness was higher than TMD patients with acute pain, and the amount of daytime sleepiness was higher in the group of chronic pain. In TMD patients with chronic pain, only the poor sleeper(PSQI>5) presented mean ESS>10(diagnostic criteria of daytime sleepiness). There was no correlation between pain intensity and sleep quality or daytime sleepiness. The result of ApnealinkTM for screening of sleep related breathing disorder showed that only 1 patient presented AHI>5 among 19 participants. TMD patients with chronic pain presented poor sleep quality and excessive daytime sleepiness similar to other chronic pain patients. Evaluation of sleep state by questionnaire might be useful for diagnosis and management of TMD, because sleep disturbance decreases pain threshold and pain disturbs sleep. In addition, sleep-screening device would be useful for screening sleep related breathing disorder in dental clinic.

Effects of Dermal Cell Combination on the Formation of Basement membrane and Epidermis in Skin Equivalents (진피세포의 조성이 인공피부의 기저막과 표피형성에 미치는 영향)

  • Li, Hai-Lan;Jeong, Hyo-Soon;Kim, Jan-Di;Yun, Hye-Young;Baek, Kwang-Jin;Kwon, Nyoun-Soo;Min, Young-Sil;Park, Kyoung-Chan;Kim, Dong-Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.38 no.3
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    • pp.219-224
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    • 2012
  • European Union prohibited the marketing of cosmetic products containing constituents that have been examined through animal experiments. Thus, non-animal test models are needed to replace animal experiments. The reconstructed skin models are important as a test system for cosmetic, pharmaceutical, and medical device safety testing. In the present study, we tried to develop an optimal skin equivalent model containing basement membrane and epidermis. For this purpose, we used mesenchymal stem cells (MSCs) and/or preadipocytes as well as fibroblasts as the dermal matrix cells. The formation of basement membrane and epidermis was verified by immunohistochemical stains. Among various models, the epidermis was thickest when MSCs were used in the dermal matrix. Furthermore, PCNA and involucrin distribution showed that dermal matrix with MSCs resembled human skin. Therefore, skin equivalents with MSCs could be developed as a non-animal test model to replace animal experiments.

The Influences of Perceived Risk on Attributes of Smart Clothing -Comparison among Korea, Spain, and U.S.- (지각된 위험이 스마트 의류 속성에 미치는 영향 연구 -한국, 스페인, 미국 비교 연구-)

  • Ko, Eun-Ju;Okazaki, Shintaro;Lee, Chang-Han;Yun, Hye-Lim
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.6
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    • pp.893-903
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    • 2009
  • Smart clothing represents the future of both the textile/clothing industry and electronic industry and has an effort to make electronic devices a genuine part of our daily life. The researches about technologies innovation and application of smart clothing can be found in previous studies. But consumer researches about perception or attitude toward smart clothing can be hardly found. Therefore, we proposed a conceptual framework that explores the impact of perceived risks on perceived attributes to adopt smart clothing. In addition, we compared differences of this framework among three counties. Korea, U.S. and Spain. Based on the literature review and hypotheses development, a research model was constructed. After data analysis using Amos 7.0, the results can be concluded as following: First, the influences of psychological risk among Korea, U.S. and Spain are same. Psychological risk has negative effect on relative advantage and complexity, but has positive effect on trialability. Second, loss risk was found to have nothing to do with relative advantage. But it negatively influences complexity for Korean consumers and positively influences trialability for both Korean and American consumers. Third, the influences of performance risk for different consumers are different. At last, based on our discussion, some implications were also concluded.

Impact Resistance Evaluation of RC Beams Strengthened with Carbon FRP Sheet and Steel Fiber (CFRP 시트 및 강섬유로 보강된 RC 보의 충격저항 성능 평가)

  • Cho, Seong-Hun;Min, Kyung-Hwan;Kim, Yun-Ji;Yoon, Young-Soo
    • Journal of the Korea Concrete Institute
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    • v.22 no.5
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    • pp.719-725
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    • 2010
  • The analysis and experimental program of reinforced concrete (RC) structures for resistance against such extreme loads as earthquake, blast, and impact have been carried by many researchers and designers. Under the extreme loads, a large amount of energy is suddenly exerted to the structure, hence if the structure fails to absorb the impact energy, catastrophic collapse may occur. To prevent catastrophic collapse of structures, reinforced concrete must have adeguate toughness or it needs to be strengthened. The FRP strengthening method and SFRC are studied widely in resistance of impact load because of their high energy absorption capacity. In this study, drop weight impact tests were implemented to evaluate the impact resistance of SFRC and FRP strengthened RC beam while the total steel fiber volume fractions was fixed at 0.75% carbon FRP flexural strengthened RC beams. Futhermore, to prevent the shear-plug cracks when the impact load strikes the beams, additional FRP shear strengthening method are applied. The experimental, results showed that the FRP strengthened RC SFRC beams has high resistance of shear-plug cracks and crack width and SFRC has high resistance of concrete spalling failure compared to normal RC beams. The FRP flexural and shear strengthening RC beams has weakness in the spalling failure because the impact load concentrated the concrete face which is not strengthened with FRP sheets.

An experimental study on the cytotoxicity of orthodontic wires (교정용 호선의 세포독성에 관한 실험적 연구)

  • Lim, Yong-Kyu;Yang, Won-Sik
    • The korean journal of orthodontics
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    • v.26 no.5 s.58
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    • pp.591-599
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    • 1996
  • This study was undertaken to investigate the cytotoxicity of orthodontic wires after doing various treatments to the wires. 018x025 inch Stainless steel(A) and Co-Cr(B) wires were used and each of them were divided into 4 groups. A-1 and B-1 groups were as received state, and A-2 and B-2 groups were heat treated. A-3 and B-3 groups were electropolished after heat treatment, and A-4 and B-4 groups were soldered with Ag-solder. Each group had 3 wires and these were sterilized with Ethylene Oxide gas. We used human gingival fibroblast cell culture and agar overlay technique to investigate the cytotoxicity of each group of wires. The cytotoxicity of wire was assessed using reaction index (zone index/lysis index). The findings of this study were as follows. 1. Both of the stainless steel wire and Co-Cr wire showed no cytotoxicity in as received state. 2. Heat treatment or electropolishing of the wires had no effect on the cytotoxicity of the wires 3. Soldered stainless steel wires showed a little wider zone of discoloration than soldered Co-Cr wires, but the zone index and cytotoxicity(reaction index) was not different. 4. Soldered wires showed moderate cytotoxicity in both of the wires.

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상온에서 제작된 다결정 인듐갈륨 산화물(IGO) 투명 박막트랜지스터 제조 및 특성 연구

  • Jo, Gwang-Min;Jeong, Yeon-Hu;Lee, Jun-Hyeong;Kim, Jeong-Ju;Heo, Yeong-U
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.345-345
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    • 2014
  • 최근 디스플레이 기술은 급속도로 발전해 가고 있다. 정보화 기술의 발전으로 언제 어디서나 쉽게 정보를 얻을 수 있는 유비쿼터스 시대로 접근하고 있으며, 휴대가 간편하고 이동성을 가진 휴대용 기기가 인기를 끌고 있다. 이에 따라 더 얇고 더 가벼우며 휴대하기 쉬운 디스플레이가 요구 되고 있고, 더 나아가 떨어뜨려도 깨지지 않고 유연하며, 디자인 변형이 자유로우며, 때론 종이처럼 접거나 휘어지거나 두루마리처럼 말을 수 있는 이른바 "플렉서블 디스플레이"에 대한 필요성이 점점 대두되고 있다. 이러한 첨단 디스플레이의 핵심 소자 중 하나는 산화물 박막 트랜지스터 이다. 산화물 반도체는 넓은 밴드갭을 가지고 가시광선 영역에서 투명하며, 높은 이동도를 가지고 있어 차세대 평판디스플레이, 투명디스플레이 및 플렉서블 디스플레이용 박막트랜지스터(TFT)를 위한 채널층으로써 광범위하게 연구되고 있다. 하지만 현재 대부분의 산화물 박막 트랜지스터 제조 공정은 고온에서의 열처리를 필요로 한다. 고온에서의 열처리 공정은 산화물 박막의 제조 공정 단가를 증가시키는 문제점이 있으며, 산화물 박막이 형성되는 기판의 녹는점이 낮은 경우에는 상기 기판의 변형을 가져오므로(예를 들면, 플라스틱 기판, 섬유 기재 등), 상기 산화물 박막이 적용되는 기판의 종류에 제한이 생기는 문제점이 있었다. 이에 플렉시블 디스플레이 등을 위해서는 저온공정이 필수로 선행 되어야 한다. 산화물 TFT는 당초, ZnO계의 재료가 연구되었지만 2004년 말에 Hosono 그룹이 Nature지에 "IGZO (In, Ga, Zn, O)"을 사용한 TFT를 보고한 이후 IGZO, IZO, ISZO, IYZO, HIZO와 같은 투명 산화물반도체가 TFT의 채널물질로써 많이 거론되고 있다. 그 중에서 인듐갈륨 산화물(IGO)는 삼성분계 n-형 산화물 반도체이고, 채널 이동성이 좋고 광투과도가 우수해 투명 TFT에 매우 유용하게 사용할 수 있다. 이 실험에서 우리는 인듐갈륨 산화물 박막 및 트랜지스터 특성 연구를 진행하였다. 인듐갈륨 산화물 박막은 상온에서 rf-magnetron sputtering법을 사용하여 산소분압 1~10%에서 증착 되었다. 증착된 인듐갈륨 산화물 박막은 cubic $In_2O_3$ 다결정으로 나타났으며, 2차상은 관찰 되지 않았다. 산소분압이 10%에서 1%로 변함에 따라 박막의 전도도는 $2.65{\times}10^{-6}S/cm$에서 5.38S/cm 범위에서 조절되었으며, 이를 바탕으로 인듐갈륨 박막을 active층으로 사용하는 bottom gate 구조의 박막트랜지스터를 제작 하였다. 인듐갈륨산화물 박막트랜지스터는 산소분압 10%에서 on/off 비 ${\sim}10^8$, field-effect mobility $24cm^2/V{\cdot}S$를 나타내며 상온에서 플렉서블용 고 이동도 소자 제작의 가능성을 보여준다.

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Synthesis and Characterization of Interfacial Properties of a Cationic Surfactant Having Three Hydroxyl Groups (세 개의 히드록실기를 가진 양이온 계면활성제 합성 및 계면 특성에 관한 연구)

  • Lee, Byung Min;Kim, Ji-Hyun;Kim, Sung Soo;Lim, Jong Choo
    • Applied Chemistry for Engineering
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    • v.23 no.5
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    • pp.433-439
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    • 2012
  • In this study, a cationic surfactant BHMAS (N,N-bis-(3'-n-dodecyloxy-2'-hydroxypropyl)-N-methyl-2-hydroxyethylammonium methyl sulfate) having two lauryl and three hydroxyl groups was synthesized by the reaction of n-dodecyl glycidyl ether and 2-aminoethanol followed by the quarternization with dimethyl sulfate. The structure of the product was elucidated by $^{1}H-NMR$ and FT-IR. The CMC (critical micelle concentration) and surface tension of BHMAS at CMC condition were found to be $9.12\;{\times}\;10^{-4}$ mol/L and 28.71 mN/m respectively. Dynamic surface tension measurements using a maximum bubble pressure tensiometer indicated that a relatively long time was required to saturate the interface between air and aqueous surfactant solution. The interfacial tension measured between 1 wt% surfactant solution and n-decane reached an equilibrium value of 0.045 mN/m in 5 min. The adsorption capacity of the synthesized surfactant was observed to be excellent, which suggests that the surfactant can be used as a softening agent during a laundry process.

Method Validation for Monitoring of Agricultural Worker Exposure to Insecticide Fenthion (살충제 Fenthion에 대한 농작업자 노출 측정을 위한 분석/시험방법 검증)

  • Kim, Eun-Hye;Lee, Hye-Ri;Choi, Hoon;Moon, Joon-Kwan;Hong, Soon-Sung;Jeong, Mi-Hye;Park, Kyung-Hun;Lee, Hyo-Min;An, Xue Hua;Kim, Jeong-Han
    • The Korean Journal of Pesticide Science
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    • v.15 no.4
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    • pp.357-365
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    • 2011
  • Exposure measurement of agricultural worker to pesticide is one of important part of health risk assessment of pesticide. Therefore exposure matrices, apparatus, instruments and methods must be validated in advance to field experiment. In this study, method validation with an organophosphorus insecticide fenthion was carried out for exposure monitoring of agricultural worker. LOD and LOQ were 0.01 and 0.05 ng, respectively. Calibration curve linearity ($R^2$ > 0.999) and reproducibility (C.V. < 3%) were also excellent. Recovery at LOQ, 10LOQ and 100LOQ levels from gloves, socks, mask, patch, solid sorbent, glass fiber filter was 76~113% (C.V. < 3%). Trapping efficiency was 95~105% while no breakthrough was observed. Method validation for the exposure monitoring was established successfully through several experiments. Such method validation can be usually performed in laboratory and not much different for each pesticide so that, this techniques will be applied widely in research for pesticide exposure monitoring by combination with body surface area and respiration rates.

Direction toward Economic Development of Southwest Area of Jeonnam Province through Construction of Airport and Port Supporting Complex (공항만배후단지 조성을 통한 전남 서남권 경제발전방향에 관한 연구)

  • Park, Soomyung
    • Journal of Korea Port Economic Association
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    • v.29 no.3
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    • pp.39-72
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    • 2013
  • As a regional development gap between Southwest and Southeast of Jeonnam Province are becoming more serious, it is highly time to come up with measures for the balanced development of the two areas. This paper suggests construction of the Airport and Port Supporting Complex in apparent efforts to reduce the gap between the two areas and facilitate the Southwest economy. The Supporting Complex aims to constitute a triangle industrial cluster which is classified into the following three categories; 1. Traditional competitive industries 2. New growth engine industries 3. Attraction of companies u-turning from abroad such as China etc. To provide one-stop service through set-up of R&D Business Center is the heart of this triangle core. This paper had LQ and Shift&Share Analysis in an attempt to search for competitive industries among the traditional industries in Mokpo-si(city) and Muan-gun(county) of Jeonnam Province. As a result of the analysis, metal manufacturing industry and metal-working process products industry have been found competitive in the two areas. Among the new growth engine industries, this paper suggests precision instruments industry and advanced parts industry for utmost strengths of airport and port while u-turning industries from abroad include higher value-added textile industry and fashion industry. It is expected that all of above-mentioned industries for the triangle industrial cluster will contribute to laying the groundwork to develop regional economy further and create more jobs in the Southwest area of Jeonnam Province.

A Study on The Development and Evaluation of The Pine Needle Flavor oil (솔잎 향미유의 제조와 기호성에 관한 연구)

  • 원종숙;안명숙
    • Korean journal of food and cookery science
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    • v.17 no.2
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    • pp.129-138
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    • 2001
  • In this study, development of the pine needle flavor oils and their application to foods, especially to traditional Korean foods, were investigated. The pine needle flavor oils were prepared by the autoclaving method, and their volatile flavor components(VFCs) were determined by capillary gas chromatographic method The major flavor components of the pine noddle flavor oil were a -pinene 31.1%, pentane 9.8%, tricyclene 7.5%, camphene 6.8%, hexanal 6.2%, propane 6.0%, ${\beta}$-pinene 5.6%, limonene 3.9%. The acceptability of the pine needle flavor oils, sensory evaluation including a preference test and quantitative descriptive analysis(QDA), of the pine needle flavor oil, a sesame oil, and a blended oil (pine needle flavor oil : sesame oil 50 : 50 v/v) was carried out. The blended oil and sesame oil showed much higher preference scores than the pine needle flavor oil, and blended oil was almost as acceptable as sesame oil(P < 0.05). The results seem to indicate that blended oil can be used as a unique substitution for sesame oil in some foods, especially in some traditional Koran food.

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