• 전자공학회논문지 IE
• /
• v.47 no.4
• /
• pp.28-33
• /
• 2010

In this paper, we proposed to the inspection algorithm for cap, Electric fuse is an over current and circuit protection device which is occurred in electric & electronic appliance. Also the fuse are protection the second hazard at arc etc. Fuse are interest regarding a safety increased. Consequently, the fuse came to be very important. Cap inspection algorithm is designed for the cap of fuse. CCD camera is monitering the solder of cap distribution map. The conditioning of fuse cap; suming all searching data with non solder area. the area is bigger reference data then the cap is bad cap.

• Clinical and Experimental Pediatrics
• /
• v.49 no.10
• /
• pp.1056-1060
• /
• 2006

Purpose : As hearing ability affects language and cognitive development, early detection and intervention of congenital hearing defects is very important. We analyzed the result of newborn hearing screening using automated auditory brainstem response and estimated the incidence of congenital hearing defects in newborn infants in Korea. Methods : Hearing screening tests were done on 7,218 newborn infants who were delivered at Cheil General Hospital from July 1, 2004 to June 30, 2005. The first screening test was done on the second day of life with automated auditory brainstem response(AABR) using $ALGO{\bigcirc}^{(3)}$ Newborn hearing screener($Natus^{(R)}$ Medical Incorporated, San Carlos, USA) with 35 dB sound level. The newborn infants who did not pass the initial screening test took the second screening AABR test before discharge from the nursery. Infants who did not pass these screenings at the nursery were followed up at the Department of Otorhinolaryngology, Samsung Seoul Hospital. Results : Total 7,218 infants(83.3 percent of total 8,664 live births of the Cheil General Hospital) were screened in the nursery, and 55 of them failed to pass the newborn screening. Among 55 infants who were referred, six were lost during follow-up, and 14 were confirmed as hearing impaired. Six of them(42.8 percent) do not have any risk factors for hearing impairment. We can estimate that the incidence of hearing defects is about 1.9-2.8 per 1,000 live births. Conclusion : Automated auditory brainstem response is an effective tool to screen the hearing of newborn infants. Congenital hearing loss is more frequent than metabolic diseases on which screening tests are available in the newborn period. About 40 percent of infants who have hearing defects do not have any risk factors for hearing impairment. Therefore, universal newborn hearing screening must be recommended to all neonates.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2022.07a
• /
• pp.307-310
• /
• 2022

4차 산업혁명의 기술이 발전함에 따라 세계는 눈부시게 발전하고 있다. 그러나 그와 동시에 어르신들의 치매로 인한 사회적 비용의 증가로 발생하는 문제점 또한 무시하지 못할 수준에 이르렀다. 이에 조기에 치매를 선별하여 예방하는 것이 중요시되었으며 다양한 연구기관에서는 빠르고 쉽게 치매의 전 단계인 경도인지장애를 선별하고자 여러 선별 검사지를 제작하여 경도인지장애 선별을 통한 치매를 예방하는 데 노력하는 중이다. 하지만 다양한 상황으로 각각의 효율성이 경도인지장애 선별에 대한 기대에 미치지 못하고 있다. 그리하여 본 연구는 기존에 개발된 경도인지장애 선별지 들을 비교 분석 및 코로나 상황에 적합하게 비대면 방식으로 경도인지장애 선별이 가능하도록 보다 효율적으로 개선하였으며 이를 IoT 기기에 접목하였다. 또한 IoT 기기는 어르신들의 경도인지장애 선별검사에 대한 부담감을 줄이고자 친근한 인형 형태로 개발하였으며 상호작용을 위한 기능 제작을 통하여 마음 돌봄 서비스를 구현하였다.

• Advanced Industrial SCIence
• /
• v.1 no.2
• /
• pp.30-36
• /
• 2022

Even in 2022, when medical science is highly developed, pandemic infectious diseases continue to occur. COVID-19, which occurred in 2019, is highly contagious and has caused many infections. In Korea, temporary screening clinics, such as screening clinics and respiratory clinics, have been added to prevent the spread of COVID-19, but there are problems such as a bottleneck due to the large number of people who want to take the test, and this creates a bottleneck. In order to solve the problem, this study aims to identify people who want to be tested for COVID-19 in a screening clinic in real time. It uses a real-time database to link with screening clinics and provides users with the real-time status of each screening clinic. Using the app, users can check the status of screening clinics in real time and can select a clinic smoothly.

• Journal of Gastric Cancer
• /
• v.9 no.4
• /
• pp.167-171
• /
• 2009

Purpose: This study was done to determine the usefulness of serum pepsinogen (PG) levels as a screening method for gastric cancer, and to assess the relationships between serum PG and clinicopathologic factors of gastric adenocarcinoma. Materials and Methods: Serum PG concentrations were measured in 94 subjects who were classified into (a) a control group (50 subjects) without abnormal endoscopic finding on a health checkup, or (b) a gastric cancer group (44 subjects) who had surgery at Daegu Catholic University Hospital between Nov. 2008 and May 2009. Receiver operator characteristic curves were utilized to select the most suitable test. Using different cutoff points, sensitivity and specificity were calculated. We compared preoperative serum PG levels with several clinicopathologic findings for patients with gastric adenocarcinoma. Results: The Serum PG I：II ratio was the most useful as a screening test. The sensitivity and specificity of PG screening for gastric cancer were, respectively, 81.8% and 82%. The cut off point correlated with the type of intestinal cancer (Lauren classification; P=0.003), tumor stage (P=0.001), and gastric adenocarcinoma with peritumoral chronic atrophic gastritis (P=0.036). Conclusion: Serum PG levels were found to be a potentially useful screening test and to correlate with clinicopathologic factors in gastric cancer patients. But, in order to use serum PG found in a health checkup for gastric cancer as a clinical application a large scale study is recommended.

• Journal of Genetic Medicine
• /
• v.5 no.1
• /
• pp.21-25
• /
• 2008

Purpose : In recent years, many countries have adopted newborn screening programs that use tandem mass spectrometry (MS/MS) to screen and the number of diseases screened has also increased. We began screening for inherited metabolic disorders using MS/MS in April, 2001. Our goal was to determine the overall prevalence of metabolic disorders and to assess the effectiveness of newborn screening by MS/MS in Korea. Methods : From April, 2001 to December, 2007, we screened newborns and high risk groups using MS/MS. Acylcarnitines and amino acids were extracted and butylated and were introduced into the inlet of MS/MS. Confirmatory testing including a repeat newborn screening, and urine organic acid and plasma amino acid analysis were performed on a case-by-case basis. Results : The total number of screened subjects 284,933 which comprised 251,799 neonates and 33,134 high risk subjects. The recall rate was 0.4% (1158 tests) and true positive cases were 117 (0.04%). Confirmed metabolic disorders (newborn/high risk group) were as follows; 78 (25/53) amino acid disorders, 27 (16/11) organic acid disorders, and 12 (5/7) fatty acid oxidation disorders. The estimated prevalence of inherited metabolic diseases in newborns was 1:5,000 and that in the total group was 1:2,000. Conclusion : Newborn screening by MS/MS improved the detection of many inherited metabolic disorders. We therefore propose that all newborns be screened by a MS/MS national program and followed-up using a systemic organization strategy.

• Journal of The Korean Society of Inherited Metabolic disease
• /
• v.16 no.1
• /
• pp.1-9
• /
• 2016

Newborn screening (NBS) is important if early intervention is effective in a disorder and if there are sensitive and specific biochemical markers to detect disorder. Methionine is a useful marker to detect abnormal methionine-homocysteine metabolism, especially homocystinuria which needs urgent medical intervention. However, hypermethioninemia could occur in other metabolic disorder including liver disease, tyrosinemia type I, methionine adenosyltransferase (MAT) I/III deficiency, glycine N-methyltransferase (GNMT) deficiency, or adenosylhomocysteine hydrolase deficiency. However, experience with NBS for homocystinurias and methylation disorders is limited. Especially, MAT I/III deficiency which is the most common cause of persistent hypermethioninemia have two inheritance, autosomal recessive (AR) and autosomal dominant (AD), and their clinical manifestation is different between AR and AD. Here, author reviewed recent articles of guideline and proposed guideline for homocystinuria and methylation disorder.

• Phonetics and Speech Sciences
• /
• v.16 no.1
• /
• pp.49-55
• /
• 2024

This study aims to develop a three-sentence speech screening test to evaluate speech development in 4-year-old children and provide standards for comparison with peers. Screening tests were conducted on 24 children each in the first and second halves of 4 years old. The screening test results showed a correlation of .7 with the existing speech disorder evaluation test results. We compared whether there was a difference between the two groups of 4-year-old in the phonological development indicators and error patterns obtained through the screening test. The developmental indicators of the children in the second half were high, but there were no statistically significant differences. The Korean Speech Sound Analysis Tool (KSAT) was used for all analyses, and the automatic analysis results and contents of the clinician's manual analysis were compared. The degree of agreement between the automatic and manual error pattern analyses was 93.63%. The significance of this study is that the standard of speech of a 4-year-old child of the speech screening test according to three sentences at the level of elicited sentences, and the applicability of the KSAT were reviewed in both clinical and research fields.

• Proceedings of the KAIS Fall Conference
• /
• 2009.05a
• /
• pp.599-602
• /
• 2009

본 연구는 2006년 3월부터 2007년 2월까지 일개 대학병원에서 출생한 고위험군 신생아 121명을 대상으로 청각선별검사인 자동화 유발이음향방사와 확진검사인 청성뇌유발전위검사를 실시하여 임상양상과 청각장애 발생률, 검사소요 시간에 대해 조사하였다. 결과는 다음과 같다. 1. 청각장애발생률은 전체 고위험군 신생아 121명 중 5명의 신생아가 난청으로 조기에 진단되었다. 2. 난청으로 확진 받은 신생아 5명의 관련 질병을 살펴보면 고빌리루빈혈증 2명, 저체중 1명, 구개열 1명, 다운증후군 1명이었다. 3. 난청으로 확진 받은 신생아 5명의 청력손실정도는 양측 고도난청 1명(70dB), 양측 중도난청 2명(55dB), 편측성 난청 2명으로 나타났다. 4. 검사소요 시간은 선별검사인 유발이음향방사 검사를 실시하는 데 소요된 총 시간의 평균은 $107.5{\pm}65.2$초였고, 확진검사인 청성뇌유발전위 검사를 실시하는 데 소요된 총 시간의 평균은 $1,500{\pm}90.1$초가 소요되었다. 5. 연구를 진행하는 도중 11명의 고위험군 신생아가 이사, 연락처 변경, 경제적 사정으로 추적검사에 참여하지 않았다. 신생아 난청은 다른 질병에 비해 발병률이 높은 선천성 질환으로서 모든 신생아를 대상으로 청각검사를 실시하여 난청의 조기진단에 대한 선별검사의 정착이 필요하다고 생각된다.

• Journal of The Korean Society of Inherited Metabolic disease
• /
• v.16 no.2
• /
• pp.70-78
• /
• 2016

21-hydroxylase deficiency (21-OHD), most common form of congenial adrenal hyperplasia, is categorized into classical forms, including the salt-wasting (SW) and the simple virilizing (SV) types, and nonclassical (NC) forms based on the severity of the disease. Newborn screening for 21-OHD has been performed in Korea since 2006. $17{\alpha}$-hydroxyprogesterone (17-OHP) is a marker for 21-OHD and is measured using a radioimmunoassay or a fluoroimmunoassay. Premature and low birth weight infants are likely to give false positive 17-OHP findings, therefore, cutoff values for these infants should be determined based on gestational weeks or birth weight. ACTH simulation test is helpful when the 17-OHP shows equivocal increase, and it is gold standard for diagnosis of NC type. Recently, liquid chromatography linked with tandem mass spectrometry was developed for rapid, highly specific, and sensitive analysis of multiple analytes. Molecular analysis of CYP21A2 is useful for confirming diagnosis of mild SV or NC type, predicting prognoses, and genetic counseling. In order to make newborn screening for 21-OHD more efficient, early detection of boy with SW type, early determination of girl with ambiguous genitalia, detection of NC type, and overcoming of false positive in premature and low birth weight infants should be considered. Above all, early treatment should be started when the patient is suspected as having 21- OHD clinically before confirming the diagnosis to prevent adrenal crisis. Here, author reviewed recent articles of guideline and proposed guideline for 21-OHD.