• Proceedings of the Safety Management and Science Conference
• /
• 2008.11a
• /
• pp.241-246
• /
• 2008

This paper introduces nine acceptance sampling plans by attribute based on screening (sorting, rectifying). Revised KS standards for single and double acceptance sampling by attribute such as Dodge - Romig : 1998, KSA ISO 2859 - 2 : 2001, 13448 - 1, 2, MIL - STD - 105E : 1989, KSA IEC 60410 and ANSI/ASQ Z1. 4 : 2003 are presented.

• Journal of the Korean Society of Radiology
• /
• v.7 no.6
• /
• pp.389-395
• /
• 2013

This study intended to investigate the optimum conditions for lumbar test that has the highest level of irradiation conditions among general test sites. To to this, the most widely used irradiation conditions in terms of statistics were set as standards; test groups applied with DMF were selected; tests groups suitable for clinical trials were selected by using suggested patient dose. Blind tests were conducted by 10 specialists and radiologists. The results suggested that under the optimum conditions, the radiation dose reduction of 2.09 mGy, 4.42 mGy and 3.65 mGy can be achieved in forward-backward test, lateral test and 4-direction test, respectively. There is a need of further studies on the optimization of irradiation conditions in accordance with the conditions of patients.

• The Journal of the Korea Contents Association
• /
• v.21 no.1
• /
• pp.465-474
• /
• 2021

Corona-19, a disease caused by 'Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)', was declared a global pandemic by the World Health Organization (WHO) in March 2020, and a real-time polymerase chain reaction test is performed as a diagnostic test for screening and confirmation in most countries. However, not only the target genes and protocols differ by countries, but also the procedures for reading the diagnosis results are diverse, so the criteria for confirmed patients differ by country. Therefore, in this review, we discussed the target genes, test techniques, and diagnostic criteria for each country notified by WHO. And the specificity and sensitivity, limits of detection, positive and negative controls, false positive bacteria candidates, and specimens, and the specifics of the control setting were also described. In addition, the characteristics of Korea's test were compared to each country's one. Finally, in order to obtain the same diagnosis result for SARS-CoV-2 in the future, standardized diagnosis methods and result interpretations for Corona-19 diagnosis were proposed.

• Clinical and Experimental Pediatrics
• /
• v.49 no.8
• /
• pp.845-850
• /
• 2006

Purpose : To assess the incidence of neonatal hearing loss in a neonatal intensive care unit and the relative importance of risk factors for hearing imparement in a neonatal intensive care unit which the Joint Committee on Infant Hearing(JCIH) had recommended. Methods : One thousand, two hundred and one newborns admitted to the Good Moonhwa Intensive Care Unit from May 2003 to December 2005 were assesed using the automated auditory brainstem response(AABR). The screening was performed on those aged more than 36 weeks and weighing more than 2,200 g. We divided the infants into two groups, 'pass' and 'refer'. The 'refer' group were retested one month later, and if classified as 'refer' during the retest, were referred to a hearing impairment clinic. Results : From the 1,201 neonates, 1,187(98.8 percent) passed the test and 14(1.2 percent) failed. 293(24.4 percent) of the 1,201 neonates had a risk factor for hearing impairment; 282(96.2 percent) passed the test and 11(3.8 percent) failed. The group with risk factors were shown to have a higher incidence of hearing loss(P<0.001). The neonates in the refer group were shown to have a higher incidence of ototoxic drugs(P<0.001), low birth weight(<1,500 g)(P<0.001) and craniofacial anomalies(P=0.007). On the other hand, there were no statistical differences between the pass and refer groups in congenital infection, hyperbilirubinemia, bacterial meningitis, low Apgar scores, prolonged mechanical ventilation and syndromes known to include hearing loss. Conclusion : In order to identify hearing-impaired infants within an appropriate period, neonatal hearing screening tests and identification of the risk factors for neonatal hearing loss are important.

• Neonatal Medicine
• /
• v.16 no.2
• /
• pp.213-220
• /
• 2009

Purpose: Hearing loss is one of the common birth defects in humans, with a reported prevalence of 1-3 per 1000 newborns. We investigated the incidence of hearing loss and evaluated the use of neonatal hearing screening test in neonatal intensive care unit (NICU) graduates who are at greater risk for hearing loss than normal newborns. Methods: The neonates admitted to the NICU of Asan Medical Center from 1 March, 2003 to 30 March, 2008 who were available for follow-up were included. Those who failed the first auditory brainstem response prior to discharge were retested with the stapedial reflex test, auditory brainstem response and tympanometry in the Otolaryngology department. Results: Of 2,137 neonates, 2,000 (93.5%) neonates were tested prior to discharge. Sixty-seven neonates (3.4%) failed the first newborn hearing screening test. Of 67 infants, 52 infants were retested for a second hearing test. Excluding 10 infants (19.2%) who were lost during follow-up, 16 infants were confirmed to have hearing impairment of which 12 and 4 infants had unilateral and bilateral hearing loss, respectively. Of 16 infants, 5 did not meet the criteria set by the Korean National Health Insurance Corporation. Conclusion: The prevalence of hearing impairment in NICU graduates is about 0.8%, excluding those who were lost for follow up, necessitating a systemic and effective hearing assessment program among these high risk infants and more generous national insurance coverage.

• Journal of Genetic Medicine
• /
• v.7 no.1
• /
• pp.59-66
• /
• 2010

Purpose: Quantitative fluorescent polymerase chain reaction (QF-PCR) allows for the rapid prenatal diagnosis of common aneuploidies. The main advantages of this assay are its low cost, speed, and automation, allowing for large-scale application. However, despite these advantages, it is not a routine method for prenatal aneuploidy screening in Korea. Our objective in the present study was to validate the performance of QF-PCR using short tandem repeat (STR) markers in a Korean population as a means for rapid prenatal diagnosis. Material and Methods: A QF-PCR assay using an Elucigene kit (Gen-Probe, Abingdon, UK), containing 20 STR markers located on chromosomes 13, 18, 21, X and Y, was performed on 847 amniotic fluid (AF) samples for prenatal aneuploidy screening referred for prenatal aneuploidy screening from 2007 to 2009. The results were then compared to those obtained using conventional cytogenetic analysis. To evaluate the informativity of STR markers, the heterozygosity index of each marker was determined in all the samples. Results: Three autosomes (13, 18, and 21) and X and Y chromosome aneuploidies were detected in 19 cases (2.2%, 19/847) after QF-PCR analysis of the 847 AF samples. Their results are identical to those of conventional cytogenetic analysis, with 100% positive predictive value. However, after cytogenetic analysis, 7 cases (0.8%, 7/847) were found to have 5 balanced and 2 unbalanced chromosomal abnormalities that were not detected by QF-PCR. The STR markers had a slightly low heterozygosity index (average: 0.76) compared to those reported in Caucasians (average: 0.80). Submicroscopic duplication of D13S634 marker, which might be a unique finding in Koreans, was detected in 1.4% (12/847) of the samples in the present study. Conclusion: A QF-PCR assay for prenatal aneuploidy screening was validated in our institution and proved to be efficient and reliable. However, we suggest that each laboratory must perform an independent validation test for each STR marker in order to develop interpretation guidelines of the results and must integrate QF-PCR into the routine cytogenetic laboratory workflow.

• Journal of the Korean Society for Precision Engineering
• /
• v.4 no.4
• /
• pp.13-21
• /
• 1987

4-4 품질관리 품질관리에는 세가지의 중요한 스텝이 있다. 첫째는 소요자재의 관리, 두째는 공장에서 조립할때의 관리, 세째는 출고관리이다. 특수 파괴설계방법론을 이 모든 과정들에 적용시켜야 할 것이다. 4-4-1 수입자재의 품질 자재들을 매입 혹은 수입할 경우에 검사하여야 할 여러가지 가 있다. 1 재료를 매입할 때 성질들이 얼마나 균일한가\ulcorner 2 최소 인성치는 얼마로 보증되어 있는가\ulcorner 3 재료들을 선별하여 거절하느나, 수락하느냐를 결정하기 위하여 어떠한 비파괴 검사법을 사용하느나\ulcorner 수입재료들에 대해서 파괴측정 시험을 해보면 실험방법이나 재료종류들에 관련되어서 실험데이타들에 전형적인 산포현상이 나타나게 마련이다. 예를들어보면 항복응력이 1400Mpa인 퀘칭하여 켐퍼링한 강의 공칭 파괴인성치는 $_{4}$는 90Mpa .root. m 일 수도 있고 60Mpa .root. m일 수도 있다. 아래 그림에 이 현상을 예시하였다. 파괴문제가 중요시 되는 부품에 대해서는 특수하게 파괴인성치를 규정하여 재료를 구입하여야 한다.

• Journal of Korean Society for Quality Management
• /
• v.16 no.2
• /
• pp.82-91
• /
• 1988

This study is concerned with the development of the economic sampling inspection plan when it is possible to carry out a nondestructive screening inspection for the rejected lots by substitutive characteristics closely related to the original quality characteristic. It is assumed that the probabilities of those errors depend linearly on the fraction defective of the process. The inspection policies considered are as follows: take a random sample of size n from the lot of size N and perform a destructive test on the sample. If the number of the defective items is not greater than a critical number C, accept the lot. Expected cost functions are obtained when the process average can be considered to follow a beta distribution and the way of finding the optimal values of (n, c) is to be explored.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
• /
• 2003.10a
• /
• pp.141.1-141
• /
• 2003

향미가 우수한 음나무 차를 제조하기 위한 최적의 기질물질 선별 실험으로 당, 아미노산 첨가하여 관능검사를 실시하였다. 여러 종류의 당(fructose)과 아미노산(threonine)을 첨가 및 혼합하여 그 혼합용액에 3시간 침지시킨 후 12시간 동안 건조하여 10$0^{\circ}C$, 4분 동안 볶음처리하여 중심합성계획에 의해 관능검사를 실시하였다. 그 결과 색상에 관한 관능평가에서 fructose 12%, threonine 2% 첨가한 음나무 껍질이 가장 우수한 것으로 나타났으며, fructose 9%, threonine 1.5% 첨가한 음나무피가 향미에서 가장 높은 관능평가를 나타내었다. 맛에서는 fructose 6%, threonine 1% 첨가한 음나무피가 가장 높은 것으로 나타났다. 또한, 전반적 기호도에서는 fructose 6%, threonine 3%와 fructose 6%, threonine 1% 첨가가 우수한 것으로 나타났다. 관능적 품질 평가에서는 아미노산보다 당의 함량에 따라 영향을 많이 받는 것으로 나타났으며 당의 함량이 높을수록 관능적 품질평가도 높은 것으로 나타났다. 특히 맛에 대한 관능평가에서 당의 함량이 증가할수록 높았으며 전반적인 기호도에서는 당과 아미노산의 함량이 증가할수록 감소하다가 일정시점 이후로는 오히려 증가하였다.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2021.01a
• /
• pp.31-32
• /
• 2021

신종 코로나바이러스 감염증(Coronavirus disease 2019; COVID-19)이 빠르게 확산됨에 따라 세계적인 전염병 대유행인 팬데믹(Pandemic)으로 선언되었다. 감염자들은 꾸준히 증가하고 있고 최근에는, 무증상 감염자들이 나타나고 있어 의심 환자를 조기에 판단하고 선별할 수 있는 기술이 필요하다. 본 논문에서는 흉부 방사선 검사(chest Radiography; CXR) 영상을 딥러닝(Deep Learning)하여 정상인, 폐렴 환자, 코로나바이러스 감염자를 분류할 수 있도록 한다.