• Korean Journal of Environmental Biology
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• v.32 no.3
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• pp.225-233
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• 2014

In this study, we investigated the changes in the physiological and histological traits of a sea squirt (Halocynthia roretzi) with the emergence of the soft tunic syndrome induced by the water temperature control (6, 9, 12, 15, 18, 21, 24 and $27^{\circ}C$). It was observed that the induction rate of the soft tunic syndrome was highest at $15^{\circ}C$, but lowest at $24^{\circ}C$. Based on the tunic color condition and contraction strength, the whole process were classified into 4 stages as S0, S1, S2 and S3. Interestingly, there were significant differences in oxygen consumption and filtration rate were observed during S0-S3. The most distinctive aspects were change of blood cell composition at stage S3, whereas multi-vacuole cell ratio was decreased by 1/2 and morula cell ratio expanded about 10 times during S0-S3. Further, change of organ structure started following the syndrome such as degeneration of epithelial cells, microfilaments, increment in hemocytes and damage in muscle fiber have been detected in tunic, siphon, branchial sac, body wall musculature and pyloric gland. Briefly, our study results indicated that the normal physiological functions of the sea squirt can be affected due to the soft tunic syndrome induced by water temperature.

• Journal of Life Science
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• v.15 no.3 s.70
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• pp.397-405
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• 2005

Sulforaphane, an isothiocyanate derived from hydrolysis of glucoraphanin in broccoli and other cruciferous vegetables, was shown to induce phase II detoxification enzymes and inhibit chemically induced mammary tumors in rodents. Recently, sulforaphane is known to induce cell cycle arrest and apoptosis in human cancer cells, however its molecular mechanisms are poorly understood. In the present study, we demonstrated that sulforaphane acted to inhibit proliferation and induce morphological changes of human cervical carcinoma HeLa cells. Treatment of HeLa cells with $10{\mu}M\;or\;15{\mu}M$ sulforaphane resulted in significant G2/M cell cycle arrest as determined by flow cytometry. Moreover, $20{\mu}M$ sulforaphane significantly induced the population of sub-G1 cells (9.83 fold of control). This anti-proliferative effect of sulforaphane was accompanied by a marked inhibition of cyclin A and cyclin-dependent kinase (Cdk)4 protein and concomitant induction of Cdc2, Cdk inhibitor p16 and p21. However, sulforaphane did not affect the levels of cyelooxygenases and telomere-regulatory gene products. Although further studies are needed, the present work suggests that sulforaphane may be a potential chemoprevetive/ chemotherapeutic agent for the treatment of human cancer cells.

• Korean Journal of Food Science and Technology
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• v.27 no.1
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• pp.134-140
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• 1995

Four different mashes using traditional methods in Korea such as Andong soju, Moonbaeju, Leekangju and Jindo hongju, were prepared for distilled liquor. The changes of pH, total acid, reducing sugar, total sugar, alcohol, solid content and ${\beta}-amylase$ activities in their mashes were studied during fermentation. Ethanol content of mashes were increased to the range of $8.8{\sim}11.2%$ after 16 days of fermentation. The group which was brewed by the first addition of mash showed higher ethanol content than the other group which was not added the ones. Total acid content of mashes increased to $0.59{\sim}1.10%$. The total sugar content was decreased to $6.70{\sim}8.94%$, and that of Leekangju type was lower than that of other fermented mashes. Reducing sugar content was in the range of $0.62{\sim}6.42%$ at the initial fermentation and decreased to $0.09{\sim}0.30%$ after 16 days of fermentation. Soju was obtained by distillation of each fermented mashes using the modified traditional Togori. After distillation of mashes, pH was increased and total acid was reduced. Sugar(3.58%) and solid(1.17%) in Leekangju were found to be leached from the mixture of pear, ginger, cinnamon, honey and curcuma rhizome.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2002.11a
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• pp.502-511
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• 2002

컴퓨터의 기술적 발전은 사회 여러 분야에 막대한 영향을 끼쳤다. 그중 악보인식분야에도 커다란 영향을 주었다. 그러나, On-line 상에서 그린 악보를 실시간으로 정형화된 악보형태로 변환하는 처리에 대한 연구가 미흡하여 이에 대한 연구가 필요하다. 본 논문에서는 실시간으로 악보를 인식하고, 사용자의 편의를 도모하기 위해 DP(Dynamic Programming) 매칭 법을 이용한 On-Line 악보인식에 관한 방법을 제안하였다. 본 연구에서는 실시간으로 입력되는 악상기호를 인식하기 위해, 가장 유효한 정보인 악상 기호내의 방향, x, y 좌표를 이용하여 벡터형태로 추출한 후 음표와 비음 표(쉼표, 기타기호)의 두개의 그룹으로 나누어진 표준패턴과의 DP매칭을 통해 인식한다. 먼저 tablet을 통해 실시간으로 악상 기호를 입력할 때 생기는 x, y좌표를 이용하여, 펜의 움직임에 대한 16방향 부호화를 수행한다. 음표와 비 음표를 구분하기 위한 시간을 줄이고자 16방향 부호화를 적용하지 않고 사사분면부호화를 적용한다. 음표를 약식으로 그릴 경우 음표 머리에 해당하는 부분의 좌표는 삼사분면에 분포하고, 폐곡선의 음표일 경우에는 좌표가 사사분면에 고르게 나타난다. 폐곡선을 제외한 음표의 머리는 폐곡선과 같은 조건이면서 입력받은 y좌표 값들 중에서 최소 값과 최대 값을 구한 다음 2로 나눈 값을 지나는 y좌표의 개수가 임의의 임계값 이상이면 음표로 판단한다. 위 조건을 만족하지 않을 경우 비 음표로 취급한다. 음표와 비 음표를 결정한 다음, 입력패턴과 표준패턴과의 DP매칭을 통하여 벌점을 구한다. 그리고 경로탐색을 통해 벌점에 대한 각각의 합계를 구해 최소 값을 악상기호로 인식하였다. 실험결과, 표준패턴을 음표와 비음표의 두개의 그룹으로 나누어 인식함으로써 DP 매칭의 처리 속도를 개선시켰고, 국소적인 변형이 있는 패턴과 특징의 수가 다른 패턴의 경우에도 좋은 인식률을 얻었다.리되고 이원화된 코드체계와 데이터 형태의 이질화를 통일하는 방법으로 데이터웨어하우스 시스템을 제시하였다. 결국 병원에서 데이터웨어하우스 시스템의 구축은 임상, 연구, 교육의 유기적 순환관계를 정립하여 지식의 순환적 고리인 수집, 공유, 확산, 재창출을 지속적 유지할 수 있는 인프라를 구축해 준다. 반면 상이한 정보들간의 충돌과 이에 따른 해석의 오류로 잘못된 의사결정을 위한 정보를 제공할 수 있고 기초정보의 접근 및 추출의 유용성에 의해서 정보유출에 대한 문제가 한계점으로 나타났다.로세스 개선을 위해서 무엇을 정말로 필요로 하는지를 밝힘으로써, 한국 소프트웨어 산업의 현실적인 특수성을 고려한 소프트웨어 프로세스 평가와 개선 모델의 개발을 위한 기초적인 자료를 제공할 것으로 예상된다. 또한, 본 연구 결과는, 우리나라 소프트웨어 조직들이 실제로 무엇을 필요로 하는지를 밝힘으로써, 우리나라의 소프트웨어 산업을 육성하기 위한 실효성 있는 정책 입안을 위한 기초 자료를 제공할 것으로 예상된다.를 검증하려고 한다. 협력체계 확립, ${\circled}3$ 전문인력 확보 및 인력구성 조정, 그리고 ${\circled}4$ 방문보건사업의 강화 등이다., 대사(代謝)와 관계(關係)있음을 시사(示唆)해 주고 있다.ble nutrient (TDN) was highest in booting stage (59.7%); however no significant difference was found among other stages. The concentrations of Ca and P were not different among mature stages. According to these results, the yellow ripe period is appropriate to harvest the whole crop rice for forage considering

• Journal of Korean Society of Forest Science
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• v.102 no.1
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• pp.113-121
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• 2013

It has been known that edges of forest fire areas play significant roles in post-fire change of forest ecosystem and recovery process. The purpose of this study was to analyze the relationships between edge formation of burned forests and landscape characteristics with consideration on spatial autocorrelation. Samcheok fire site burned in 2000 was selected as the study area. Seven hundred fifty three of 500 $m^2$ grid cells were generated for measuring landscape characteristics. This study used the topographic variables including slop, elevation, topographic wetness index, solar radiation index and proportions of fuel and land use types. In delineating landscape characteristics correlation analysis with modified t-test were performed for exploring the relationships between edge formation and landscape characteristics. The results indicated that edge formation of burned forests was positively correlated with most variables including TWI, SRI, water, paddy, developed, farm, grass, bare soil, and negatively related with elevation, slope and all fuel types. Especially TWI (r=0.437) showed a strong positive correlation with edge formation. According to the results, edge of burned forests were likely formed when proportions of heterogeneous land use types were high with mild slope and low elevation.

• Journal of the Korean GEO-environmental Society
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• v.16 no.12
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• pp.23-35
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• 2015

Nonlinear soil behavior before failure under dynamic loading is often implemented in a numerical analysis code by a mathematical fitting function model with Masing's rule. However, the model may show different behavior with an experimental results obtained from laboratory test in damping ratio corresponding secant shear modulus for a certain shear strain rage. The difference may come from an unique soil characteristics which is unable to implement by using the existing mathematical fitting model. As of now, several fitting models have been suggested to overcome the difference between model and real soil behavior but consequence of the difference in dynamic analysis is not reviewed yet. In this paper, the effect of the difference on site response was examined through nonlinear response history analysis. The analysis was verified and calibrated with well defined dynamic geotechnical centrifuge test. Site response analyses were performed with three mathematical fitting function models and compared with the centrifuge test results in prototype scale. The errors on peak ground acceleration between analysis and experiment getting increased as increasing the intensity of the input motion. In practical point of view, the analysis results of accuracy with the fitting model is not significant in low to mid input motion intensity.

• Geotechnical Engineering
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• v.13 no.4
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• pp.37-54
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• 1997

This paper is to investigate the bearing capacity and the failure mechanism of slope subjected to strip surcharges adjassent to embankment slope of sandy soil. Parametric model tests under plain strain condition were performed by changing width of footing, relative density of slope materials, and position of footing from the crest of slopes. For model tests, Jumunjin standard sand was used as the slope material and its relative density was 45% and 70%, respectively. The angle of slope was formed with 1 : 1.5 and 1 2. Rigid model footings, made of aluminuu were used with their widths of 4, 7, 10 and 12cm. For the position of model footing, position ratios, distance of model footing from the crest of slope divided by footing width, were 0, 0.5, 1, 2, 3, 4, 5. Failure mechanism was observed by using ink colored sands and markers inserted in model slopes. Ultimate bearing capacity obtained from tests was analyzed and compared with limit equilibrium method, limit analysis method and empirical equation. Characteristics of load-settlement curves and failure mechanism were also analyzed and compared with the existing theories. Thus, their effects on ultimate bearing capacity of model footing adjacent to slope were assessed.

• Journal of Dental Rehabilitation and Applied Science
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• v.30 no.4
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• pp.265-277
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• 2014

Purpose: The purpose of this study was to investigate the differences of displacement pattern depending on type of sliding jig and application method during maxillary molar distalization with temporary anchorage devices (TADs). Materials and Methods: Maxilla with normal tooth size and arch shape was selected to create a 3-dimensional finite element model, which included the bracket, orthodontic main archwire, removable sliding jig (R-jig). The orthodontic mini-implant anchorage was set 8 mm superiorly from main archwire, buccally between the second premolar and first molar. The base experimental design was Condition 1, which was composed $0.019{\times}0.025$ inch stainless steel (SS) of wire size of R-jig, 200 gm force, un-tied state. And the other designs varied to wire size of R-jig, magnitude of force. The results are as follows. Results: As the wire size of R-jig was increased, the deformation of R-jig was decreased. However, the displacement of second molar wasn't different each other. As the force to second molar was increased, the more displacement of second molar was observed, and the more distal tipping movement, vetical displacement was observed. Conclusion: R-jig can get distal teeth movement in orthodontic treatment without side effects.

• Land and Housing Review
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• v.2 no.1
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• pp.61-68
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• 2011

In order to clarify the structural performances of Welded Deformed Steel Bar Mats (WDSBM), the research stated includes the tests for standard hook of top bars of slab in concrete slab-wall joints, the tests for embedment length of top bar of slab, and the development strength tests for standard hook. The test results are as follows; (1) For slab-wall joints using WDSBM as reinforcement in slab, if the top bars of WDSBM are spliced by ordinary bars with sufficient development length and size, it is enough for the strength and crack control. (2) When WDSBM of slab is spliced in joint, the strength is increased with the embedment of bars of this WDSBM into wall. Beyond peak strength, however, ductility is diminished to that as no splice due to pull-out failure. (3) For slab-wall system, ultimate strain of concrete for flexural compression zone in lower surface of slab seems much greater than that of normal concrete beam. The reason is that normal concrete beam has the joint with $180^{\circ}$, however slab-wall joint has the $90^{\circ}$ of which concrete can be confined.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.6
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• pp.1045-1058
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• 2017

This paper is a study on railway tunnel behavior characteristic of shallow overburden under the existing road. In order to understand the behavior characteristics of the ground deformation during tunnel excavation, a horizontal rod extensometers were installed in the passage area of the shallow overburden tunnel under the road, and the measurement and analysis were carried out. To compare the in situ measurement, three dimensional numerical analysis with ground condition and construction step was carried out using MIDAS NX. As a result of the field measurement, large preceding settlement occurred where the poor ground condition with shallow overburden excavation has been conducted. As a result of the numerical analysis, the largest settlement occurred at the shallow overburden point where the ground condition was poor. Therefore, in the shallow overburden section where the soil condition is poor and a sufficient depth can't be secured and the arching effect of the ground around the tunnel can't be expected, careful attention should be paid to the application of stiffness reinforcement measures and to minimize ground loosening.