• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.18 no.2_spc
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• pp.305-315
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• 2020

For geological disposal of radioactive wastes, a method was proposed to evaluate the radionuclide transport in the biosphere by calculating the elapsed time of nuclide migration. The radionuclides were supposed to be introduced from a natural barrier and reached a large surface water body following a groundwater flow in a shallow subsurface. The biosphere was defined as a shallow subsurface environment that included aquifers on a host rock. Using the proposed method, a calculation algorithm was established, and a computer code that implemented the algorithm was developed. The developed code was verified by comparing the simulation results of the simple cases with the results of the analytical solution and a public program, which has been widely used to evaluate the radiation dose using the radionuclide transport near the surface. A case study was constructed using the previous research for radionuclide transport from the hypothetical geological disposal repository. In the case study, the code calculated the mass discharge rate of radionuclide to a stream in the biosphere. Because the previous research only demonstrated the transport of radionuclides from the hypothetical repository to the host rock, the developed code in the present study could help identify the total transport of radionuclide along the complete pathway.

• Progress in Medical Physics
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• v.21 no.3
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• pp.281-290
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• 2010

Cone-beam digital tomosynthesis (CBDT) has greatly been paid attention in the image-guided radiation therapy because of its attractive advantages such as low patient dose and less motion artifact. Image quality of tomograms is, however, dependent on the imaging conditions such as the scan angle (${\beta}_{scan}$) and the number of projection views. In this paper, we describe the principle of CBDT based on filtered-backprojection technique and investigate the optimization of imaging conditions. As a system performance, we have defined the figure-of-merit with a combination of signal difference-to-noise ratio, artifact spread function and floating-point operations which determine the computational load of image reconstruction procedures. From the measurements of disc phantom, which mimics an impulse signal and thus their analyses, it is concluded that the image quality of tomograms obtained from CBDT is improved as the scan angle is wider than 60 degrees with a larger step scan angle (${\Delta}{\beta}$). As a rule of thumb, the system performance is dependent on $\sqrt{{\Delta}{\beta}}{\times}{\beta}^{2.5}_{scan}$. If the exact weighting factors could be assigned to each image-quality metric, we would find the better quantitative imaging conditions.

• Journal of Radiation Protection and Research
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• v.40 no.3
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• pp.168-173
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• 2015

The present investigation was planned to estimate potential possibility of striped field mice, Apodemus agrarius coreae (A. a. coreae), as a biological dosimeter in radio-environmental ecology. We bred captured wild A. a. coreae at laboratory and classified taxonomically based on external, cranial and tooth characters. Organ weights and splenocytic apoptosis were observed in order to establish a basic data on radiation biology of A. a. coreae (male, 40 weeks old). The biological effects was observed at 24hrs following irradiation (doses : 0, 0.5, 1, 2 Gy, dose rate : $0.8Gymin^{-1}$, $^{137}Cs$). Only thymus weights was significantly decreased. Splenocytic apoptosis was increased after irradiation. But splenocytic apoptosis was decreased in 0.5 Gy ${\gamma}$-irradiated mice compared to those of 0, 1, 2 Gy (P < 0.05). These data suggested that events in thymus and spleen of Korean dark-striped field mice, A. a. coreae THOMAS, could be a potential radio-biological indicator in human environments.

• Journal of the Korean Society of Radiology
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• v.10 no.6
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• pp.451-456
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• 2016

Radiation dose to patient is unavoidable when diagnosis is carried out using X-ray. Radiation diagnosis using dual energy X-ray was examined to verify the possibility of medical applications by SNR and image scoring. The dual energy X-ray was realized by combining together two image plates and filter of 0.5 mm thick Cu or Al. Under one X-ray exposure, contrast enhanced image was obtained using two images of image plates. The enhanced image showed higher SNR and image score compared to the first image which was the image recorded with the first image plate. The dual energy X-ray technique would be a very useful method for obtaining higher SNR image and for realizing very low dose, and could be applied to medical applications.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.7
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• pp.492-500
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• 2011

Antibiotic resistant microbes were isolated in catfish, trout, eel and loach aquaculture effluent. The distribution of antibiotic resistant microbes in aquaculture effluent and the disinfection efficiency of antibiotic resistant microbes by electron beam irradiation were investigated. It was shown that the multi-drug resistant bacteria were Aeromonas sp., Citrobacter sp., Bacillus sp., Marinobacter sp., Pantoea sp., Pseudomonas sp. and Enterobacter sp. in aquaculture effluent. 41.7% of total strains showed the resistance against one antibiotic agent, and 58.3% of total strains showed the resistance against more than two antibiotics. It was evidently shown that the toxicity and physicochemical properties of antibiotics can be estimated using Quantitative Structure Analysis Relationship (QSAR). Electron beam irradiation was very effective for the disinfection of antibiotic resistant bacteria from aquaculture effluent, in which the disinfection efficiency was approximately 99.9% with electron beam of 1 kGy.

• Journal of Preventive Medicine and Public Health
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• v.33 no.2
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• pp.165-173
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• 2000

Objectives : To assess the availability of the glycophorin A (GPA) assay to detect the biological effect of ionizing radiation in workers exposed to low-doses of radiation. Methods : Information on confounding factors, such as age and cigarette smoking was obtained on 144 nuclear power plant workers and 32 hospital workers, by a self-administered questionnaire. Information on physical exposure levels was obtained from the registries of radiation exposure monitoring and control at each facility. The GPA mutant assay was performed using the BR6 method with modification by using a FACScan flow cytometer. Results : As confounders, age and cigarette smoking habits showed increasing trends with GPA variants, but these were of no statistical significance. Hospital workers showed a higher frequency of the GPA variant than nuclear power plant workers in terms of the NO variant. Significant dose-response relationships were obtained from in simple and multiple linear regression models. The slope of the regression equation for nuclear power plant workers was much smaller than that of hospital workers. These findings suggest that there may be apparent dose-rate effects. Conclusion : In population exposed to chronic low-dose radiation, the GPA assay has a potential to be used as an effective biologic marker for assessing the bone marrow cumulative exposure dose.

• Korean Journal of Veterinary Research
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• v.44 no.3
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• pp.323-327
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• 2004

The purpose of the present experiment was to investigate the micronuclei(MN) frequency in cytokinesis-blocked(CB) cells after various doses of gamma-rays in pig (Landrace, male, 3-month-old) and so to contribute to the clarification of the question whether these species are suitable as a target organism in the test system. The frequencies of binucleated cells, and gamma-ray-induced MN in CB cells at several doses were measured in three donors. The peaks of binucleated lymphocyte formation(22%) were found at a concentration of 2% phytohaemagglutinin(PHA) and $4{\mu}g/ml$ Cytochalasin B(Cyt-B) in pig at 72 hours after incubation. Measurements performed after irradiation showed a dose-related increases in MN frequency in each of the donors studied. When analysed by linear-quadratic model the line of best fit was $y=0.0183D+0.0124D^2+0.0133$(y = number of MN/CB cells and D=irradiation dose in Gy). In conclusion, the results demonstrate that it appears feasible to use pig as target organisms in the micronucleus test to estimate the cytogenetic damage caused by ionizing radiations or, potentially, chemical compounds.

• Journal of radiological science and technology
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• v.41 no.1
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• pp.39-45
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• 2018

The purpose of this study is to evaluate the usefulness of a software-based quality assurance system based on Volumetric Modulated Arc Therapy treatment plan. Evaluate treatment plan through the D VH analysis, PTV mean dose ($D_{mean}$) and PTV 95% dose($D_{95}$) compare the MFX based on original treatment plan, Average error rate was $0.9{\pm}0.6%$, $1.0{\pm}0.8%$, respectively. Measuring point dose using phantom and ion chamber, the average error rate between the ionization chamber and MFX was $0.9{\pm}0.7%$, $1.1{\pm}0.7%$ (high dose region), $1.1{\pm}0.9%$, $1.2{\pm}0.7%$ (low dose region). The average gamma though of MFX and $Delta^{4PT}$ is $98.7{\pm}1.2%$, $98.4{\pm}.3%$, respectively. Through this study, A software based QA system that simplifies hardware based QA procedures that involve a lot of time and effort. It can be used as a simple and useful tool in clinical practice.

• The Journal of Korean Society for Radiation Therapy
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• v.27 no.2
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• pp.115-122
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• 2015

Purpose : The aim of this study, evaluate the accuracy of HeaxPOD evo RT system using the non-coplanar beam. Materials and Methods : 13 treatment plans are used which applied non-coplanar beams and 10 treatment plans which coplanar beams are used. the correction value what adjust to 6D couch is determined by each patient's setup errors only rotation direction. The study executed followings. first, Applying the correction value, measure the point dose and calculate the ${\gamma}$-index(${\gamma}=3%$ / 3 mm, ${\gamma}=2%$ / 2 mm). second, acquire data as previous methods without correction by HexaPOD. Results : For comparing the two results, we find out the more precise applying HexaPOD by point dose 0.2% in coplanar and non-coplanar. in the case of ${\gamma}$-index<1(${\gamma}=3%$ / 3 mm), more precise 2.2% in coplanar and 7% in Non-coplanar. Particularly, ${\gamma}$-index<1(2% / 2 mm) show the difference 9.2% in coplanar and 15.1% non-coplanar between apply HexaPOD and dose not apply HexaPOD. Conclusion : Using the HexaPOD is more precise than without HexaPOD. It suggests that HexaPOD evo RT system is very useful for precise and high dose delivery.

• Progress in Medical Physics
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• v.23 no.1
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• pp.33-41
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• 2012

For applying the quality assurance (QA) of volumetric modulated arc therapy (VMAT) introduced in Eulji Hospital, we classify it into three different QA steps, treatment planning QA, pretreatment delivering QA, and treatment verifying QA. These steps are based on the existing intensity modulated radiation therapy (IMRT) QA that is currently used in our hospital. In each QA step, the evaluated items that are from QA program are configured and documented. In this study, QA program is not only applied to actual patient treatment, but also evaluated to establish a reference of clinical acceptance in pretreatment delivering QA. As a result, the confidence limits (CLs) in the measurements for the high-dose and low-dose regions are similar to the conventional IMRT level, and the clinical acceptance references in our hospital are determined to be 3 to 5% for the high-dose and the low-dose regions, respectively. Due to the characteristics of VMAT, evaluation of the intensity map was carried out using an ArcCheck device that was able to measure the intensity map in all directions, $360^{\circ}$. With a couple of dosimetric devices, the gamma index was evaluated and analyzed. The results were similar to the result of individual intensity maps in IMRT. Mapcheck, which is a 2-dimensional (2D) array device, was used to display the isodose distributions and gave very excellent local CL results. Thus, in our hospital, the acceptance references used in practical clinical application for the intensity maps of $360^{\circ}$ directions and the coronal isodose distributions were determined to be 93% and 95%, respectively. To reduce arbitrary uncertainties and system errors, we had to evaluate the local CLs by using a phantom and to cooperate with multiple organizations to participate in this evaluation. In addition, we had to evaluate the local CLs by dividing them into different sections about the patient treatment points in practical clinics.