• Journal of the Korean Society for Precision Engineering
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• v.28 no.7
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• pp.834-850
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• 2011

In this paper, a novel tissue engineering scaffold design method based on triply periodic minimal surface (TPMS) is proposed. After generating the hexahedral elements for a 3D anatomical shape using the distance field algorithm, the unit cell libraries composed of triply periodic minimal surfaces are mapped into the subdivided hexahedral elements using the shape function widely used in the finite element method. In addition, a heterogeneous implicit solid representation method is introduced to design a 3D (Three-dimensional) bio-mimetic scaffold for tissue engineering from a sequence of computed tomography (CT) medical image data. CT image of a human spine bone is used as the case study for designing a 3D bio-mimetic scaffold model from CT image data.

• Elastomers and Composites
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• v.44 no.2
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• pp.106-111
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• 2009

Tissue engineering is a research field for artificial substitutes to improve or replace biological functions. Scaffolds play a important role in tissue engineering. Scaffold porosity and pore size provide adequate space, nutrient transportation and cell penetration throughout the scaffold structure. Scaffold structure is directly related to fabrication methods. This review will introduce the current technique of 3D scaffold fabrication for tissue engineering. The conventional technique for scaffold fabrication includes salt leaching, gas foaming, fiber bonding, phase seperation, melt moulding, and freeze drying. These conventional scaffold fabrication has the limitations of cell penetration and interconnectivity. In this paper, we will present the solid freeform fabrication (SFF) such as stereolithography (SLA), selective laser sintering (SLS), and fused deposition modeling (FDM), and 3D printing (3DP).