• The Journal of the Korean bone and joint tumor society
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• v.16 no.1
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• pp.14-20
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• 2010

Purpose: To investigate prognostic factors influencing on local recurrence, distant metastasis and event-free survival of liposarcomas. Materials and Methods: Fifty-two patients managed for liposarcomas since 1993 were analyzed respectively in the view of prognostic influence of patient age, tumor size, location, histologic type, histologic grade, resection type, surgical margin, chemotherapy and radiation therapy on local recurrence, distant metastasis and event-free survival. The mean follow up period was 39 months. The univariate and multivariate regression analysis were performed for statistical evaluation. Results: The local recurrences occurred in 11 patients (21.2%) and distant metastasis in 4 patients (8%), Event-free survival rate at 4 year follow up was 67%. In univariate analysis, histologic grade, surgical margin, chemotherapy and radiation therapy were significant prognostic factors on local recurrence (p<0.05). However, histologic grade lost its significance in muitivariate analysis. Trunk location revealed higher rate of distant metastasis than extremity location. In univariate analysis on event-free survival. histologic grade and chemotherapy were significant factors (p<0.05). No factor remained significant in multivariate analysis. Conclusion: Considering selection bias, positive surgical margin was negative prognostic factor on local recurrence. Liposarcomas arisen in trunk revealed higher rate of distant metastasis. There was no independent prognostic factor on event-free survival of patients with liposarcomas.

• Journal of the Korea Society for Simulation
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• v.25 no.3
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• pp.53-63
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• 2016

We consider simulation study combining static and mobile decoys for survivability of a surface warship against torpedo attack. It is assumed that an enemy torpedo is a passive acoustic homing torpedo and detects a target within its maximum target detection range and search beam angle by computing signal excess via passive sonar equation, and a warship conducts an evasive maneuvering with deploying static and mobile decoys simultaneously to counteract a torpedo attack. Suggesting the four different decoy deployment plans to achieve the best plan, we analyze an effectiveness for a warship's survival probability through Monte Carlo simulation, given a certain experimental environment. Furthermore, changing the speed and the source level of decoys, the maximum torpedo detection range of warship, and the maximum target detection range of torpedo, we observe the corresponding survival probabilities, which can provide the operational capabilities of an underwater defense system.

• Journal of the Korean Data and Information Science Society
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• v.23 no.2
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• pp.257-269
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• 2012

Global crisis expedites the change in the environment of industry and puts small size enterprises in danger of mass bankruptcy. Because of this, domestic small size enterprises is an urgent need of restructuring. Based on the small business data registered in the Credit Guarantee Fund, we estimated the survival probability in the context of the survival analysis. We also analyzed the survival time which are distinguished depending on the types of business in the small business. Financial variables were also conducted using COX regression analysis of small businesses by types of business. In terms of types of business wholesale and retail trade industry and services were relatively high in the survival probability than light, heavy, and the construction industries. Especially the construction industry showed the lowest survival probability. In addition, we found that construction industry, the bigger BIS (bank of international settlements capital ratio) and current ratio are, the smaller default-rate is. But the bigger borrowing bond is, the bigger default-rate is. In the light industry, the bigger BIS and ROA (return on assets) are, the smaller a default-rate is. In the wholesale and retail trade industry, the bigger bis and current ratio are, the smaller a default-rate is. In the heavy industry, the bigger BIS, ROA, current ratio are, the smaller default-rate is. Finally, in the services industry, the bigger current ratio is, the smaller a default-rate is.

• Tuberculosis and Respiratory Diseases
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• v.53 no.4
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• pp.379-388
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• 2002

Background : Although patients with stage IV non-small cell lung cancer are known to have a poor prognosis, the prognostic factors for survival have not been well evaluated. Such factors may be different from those for overall survival. This study was performed to analyze the prognostic factors for survuval and the variation of survival according to metastatic organ, in patients with stage IV non-small cell lung cancer. Materials and Methods : From January 1997 to December 2000, 151 patients with confirmed stage IV non-small cell lung cancer were enrolled into this study retrospectively. The clinical and laboratory data were analyzed using univareate Kaplan-Meied and Multivariate Cox regression models. Results : On univariate analysis, age, performance status, serum albumin level, weight loss, forced expiratory volume in one second (FEV1), systemic chemotherapy, the number of metastatic organs and serum lactate dehydrogenase (LDH) level were significant factors (p<0.05). In multivariate analysis, important factors for survival were ECOG performance (relative risk of death [RR]: 2.709), systemic chemotherapy (RR: 1.944), serum LDH level (RR: 1.819) and FEV1 (RR: 1.774) (p<0.05), Metastasis to the brain and liver was also a significant factor on univariate analysis). The presence of single lung metastasis was associated with better survival than that of other metastatic organs (p=0.000). Conclusion : We confirmed that performance status and systemic chemotherapy were independent prognostic factors, as has been recognized. The survival of stage IV non-small cell lung cancer patients was different according to the metastatic organs. Among the metastatic sites, only patients with metastasis to the lung showed bettrer survival than that of other sites, while metastasis of the brain or liver was associated with worse survival than that of other sites.

• The Korean Journal of Applied Statistics
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• v.28 no.5
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• pp.965-976
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• 2015

Determining relevant variables for a regression model is important in regression analysis. Recently, a variable selection methods using a penalized likelihood with various penalty functions (e.g. LASSO and SCAD) have been widely studied in simple statistical models such as linear models and generalized linear models. The advantage of these methods is that they select important variables and estimate regression coefficients, simultaneously; therefore, they delete insignificant variables by estimating their coefficients as zero. We study how to select proper variables based on penalized hierarchical likelihood (HL) in semi-parametric frailty models that allow three penalty functions, LASSO, SCAD and HL. For the variable selection we develop a new function in the "frailtyHL" R package. Our methods are illustrated with breast cancer survival data from the Medical Center at Chonnam National University in Korea. We compare the results from three variable-selection methods and discuss advantages and disadvantages.

• 한국벤처창업학회:학술대회논문집
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• 2022.04a
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• pp.221-225
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• 2022

본 연구의 목적은 중소기업 CEO의 사내 기업가정신이 사업성과에 미치는 영향을 실증 분석하는 데 있다. 중소기업은 창업부터 성장하기까지 많은 위험요소에 노출되어 있으며 이러한 위험요소를 체계적으로 관리하고 극복하는 노하우를 쌓아 잘 활용하였을 때 경쟁시장에서 생존할 수 있다. 즉, CEO의 미래지향적이며, 창조적인 아이디어를 갖고 적극적으로 실행해보고자 하는 성향과, 위험 감수적인 기업가적 정신이 사업성과에 영향을 미칠 것이라는 가정하에 연구모형을 설정하였다. 이를 위해, 사내 기업가정신의 주요 구성요소를 '혁신성', '진취성', '위험감수성'을 독립변수로 하였고 사업성과를 종속변수로 설정하였으며, 선행연구를 기반으로 커뮤니케이션 스타일을 매개변수 채택하여 변수 간의 관계를 실증적 분석을 통하여 검증하고자 한다. 중소기업 CEO를 대상으로 하는 사내 기업가정신의 선행 연구 논문을 바탕으로, CEO가 강사인 대상으로 차별화하여 분석하고자 하였다. 또한 사내 기업가정신과 커뮤니케이션 스타일이 사업성과에 영향을 미치는지를 확인하여 사내 기업가정신의 중요성을 밝히고자 한다. CEO의 역량과 능력이 기업의 사업성과 향상에 미치는 영향요인을 분석하고, 강사가 CEO인 중소기업을 대상으로 강사의 커뮤니케이션 스타일이 조직 구성원과 사업성과 향상을 이끌어 내기 위한 참고자료로서 도움이 되고자 한다.

• Radiation Oncology Journal
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• v.10 no.1
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• pp.59-67
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• 1992

From March 1979 through December 1986, 124 patients with early stage carcinoma of the uterine cervix received curative radiation therapy. According to FIGO classification, 35 patients were stage IB and 89 were stge II A. In stage IB, five year locoregional control, five year disease free survival, and five year overall survival was $79.0\%$, $76.4\%$ and $81.8\%$, respectively. In stage II A, five year locoregional control, five year disease free survival, and five year overall survival were $78.0\%$, $66.8\%$, and $72.1\%$, respectively. To identify prognostic factors, pretreatment parameters including age, ECOG performance status, number of pregnancies, history of diabetes mellitus and hypertension, histology, size and shape of primary tumor, CT findings and blood parameters were retrospectively analyzed in terms of locoregional control, disease free survival and overall survival using univariate analysis and multivariate analysis. In univariate analysis, tumor size on physicai examination and rectal invasion on CT significantly affected locoregional control, disease free survival and overall survival. Parametrial involvement on CT was a significant prognostic factor on locoregional control and disease free survival. Hemoglobin level affected disease free survival and overall survival. Histology and age were significant prognostic factors on locoregional control. In multivariate analysis excluding CT finding, tumor size on physical examination was a significant factor in terms of locoregioal control and overall survival. Hemoglobin level was significant in terms of disease free survival. In multivariate analysis including CT, histology was a prognostic factor on locoregional control and disease free survival. Hemoglobin level and rectal invasion on CT were significant factors on locoregional control.

• Journal of Industrial Convergence
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• v.21 no.1
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• pp.111-122
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• 2023

The purpose of this study is to verify the factors affecting survival time by estimating survival rate and survival time using non-financial information of social enterprises using credit guarantee in credit guarantee institutions, and provide information to stakeholders to improve survival rate and employ to contribute to maintaining and expanding the As a research method, survival analysis was performed using a non-parametric analysis method, Kaplan-Meier Analysis. As a sample, 621 companies (577 normal companies, 44 insolvent companies) established between 2009 and 2018 were selected as the target companies. As a result of examining the factors affecting survival time by classifying social enterprise representative information and corporate information, representative credit rating, representative home ownership, credit transaction period, and corporate credit rating were derived as significant variables affecting survival time. In the future, financial institutions will be able to induce corporate soundness by reflecting factors that affect survival when examining loans for social enterprises, contributing to job retention and reduction of social costs. Supporting organizations such as the government and private organizations will be able to use it in various ways, such as policy establishment and education and training for the growth and sustainability of social enterprises. With this study as an opportunity, I hope that research will continue with more interest in the factors influencing social enterprise performance as well as corporate insolvency.

• Product Safety
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• s.199
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• pp.86-91
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• 2010

세계는 지금 기후변화와 자원위기로 심각한 위협에 직면하고 있다. 이처럼 에너지와 환경문제가 국가경제의 미래와 기업 생존을 결정하는 주요변수로 부각되고 있으나 대다수의 중소기업들은 정보 기술 인력 부족 등으로 인해 녹색성장 방향에 적절히 대응하지 못하고 있는 실정이다. 본고에서는 중소기업의 녹색성장 정책 현황 및 대응방안에 대해 알아보자 한다.

• Product Safety
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• s.197
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• pp.46-53
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• 2010

세계는 지금 기후변화와 자원위기로 심각한 위협에 직면하고 있다. 이처럼 에너지와 환경문제가 국가경제의 미래와 기업 생존을 결정하는 주요변수로 부각되고 있으나 대다수의 중소업들은 정보 기술 인력 부족 등으로 인해 녹생성장 방향에 적절히 대응하지 못하고 있는 실정이다. 본고에서는 중소기업의 녹생성장 정책 현황 및 대응방안에 대해 알아보자 한다.