• KOREAN POULTRY JOURNAL
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• v.46 no.10
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• pp.132-133
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• 2014

생식선 줄기세포 원천기술을 이용한 형질전환 조류 생산 시스템과 고효율의 유전자적 중 기술인 유전자가위법(TALEN)을 도입함으로써 기초연구 및 단기간내 새로운 가금품종 개발이 가능하게 되었다. 또한, 신약개발 및 치료물질 대량생산을 위한 형질전환가금품종 개발에 응용될 수도 있어 축산과 더불어 의약, 약학 등 매우 다양한 분야에서 가금의 활용 범위를 넓힐 수 있을것으로 기대된다. 개발된 기술은 계란성분 조절을 통한 기능성 식품 및 단백질-신약을 포함한 신물질 생산을 목적으로 하는 지식기반 생명산업의 획기적인 발전을 유도할 수 있다. 이에 유전자 가위 기법을 활용한 오브알부민 생산 유전자를 제거한 유전자 변형 닭 생산에 관한 주요내용을 소개코자 한다.

• Journal of The Korean Association For Science Education
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• v.24 no.3
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• pp.519-531
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• 2004

In recent years, there has been an increased emphasis on performance assessment to evaluate students' abilities. Our nation has introduced a change in testing and assessment. Additional work on the efficacy, reliability, and comparability in order to develop the performance assessment item has been needed in the enforcement of the 7th National Science Curriculum. Also, criteria for professional and technical standards has been needed to be developed. The purpose of this study was to draw out various key concepts and to develop achievement standards, assessment standards and performance assessment items based on the 7th National Science Curriculum on the subject matter of reproduction(chapter 13) and biological accumulation(chapter 17). And also, this study examined the validity of completed performance assessment items based on classical test theory and polytomous item response theory. Twelve key concepts in chapter 13(reproduction) and four from chapter 17(biological accumulation) were abstracted. Twenty-six achievement standards in chapter 13(reproduction), and nine in chapter 17(biological accumulation) were developed. The achievement standards were determined in terms of knowledge(K), process skill(P) and attitude(A). Twenty-five assessment standards in chapter 13(reproduction) and nine in chapter 17(biological accumulation) were developed. Based on the developed achievement standards and assessment standards, twenty-two performance assessment items(seventeen open-ended questions, three essays, and two portfolios) with concrete grading criteria were developed. Eight open-ended items were applied to 240 10th graders to evaluate reliabilities of the test which consisted of four items per each chapter. The results would be suggested that the applied items were valid for performance assessment because item difficulties and item discriminations were proper. There was not much differences in item discrimination between interpretation from classical test theory and that from polytomous item response theory. However, there were some differences in item difficulties between the interpretations of two theories because the characteristics of examinees were reflected in classical test theory.

• Korean Journal of Social Welfare
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• v.65 no.1
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• pp.5-31
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• 2013

The principle objective of this study is to determine factors affecting social participation for physically disabled people with musculoskeletal conditions (spinal cord injury, muscular dystrophy, osteogenesis imperfecta, rheumatoid arthritis) in South Korea using ICF relevant categories of the international classification index by WHO. The subjects of this study 352 people with physical disabilities, the data were collected using ICF component(body functions, body structures, activities and participation and environmental factors) and the relevant categories deprived from ICF core sets. The collected data were evaluated with descriptive analysis, ANOVA, correlation analysis, and multiple regression analysis. The results of this study can be summarized as follow. The mental function, Neuromusculoskeletal and movement-related functions, Genitourinary and reproductive functions, Skin and related structures, Learning and applying knowledge, General tasks and demands, and Mobility positively influenced social participation in people with musculoskeletal conditions. However individual factors and environmental factors didn't statistically significant affect on social participation. The implications of the study is to examine by ICF components of universal approach on disability study and utilized the relevant ICF categories as measurement tools.

• Korean Journal of Plant Resources
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• v.30 no.2
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• pp.240-264
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• 2017

The present study was carried out to identify traditional konwledges on Korean Campanulaceae plants and conduct a comprehensive review of them through analyzing phytochemistry and pharmacology of Korean Campanulaceae plants. According to the literature study, the ethnobotanical plants of Korean Campanulacae consisted of a total 18 taxa. Of them, 12 taxa including Platycodon grandiflorus, Adenophora triphylla var. japonica, Codonopsis lanceolata and others have been used as ethnomedicinal plants. These plants have been used for the treatment of 49 diseases such as cold, asthma and postnatal care. Phytochemical studies have identified the constituents present from Korean Campanulaceae (Adenophora, Codonopsis, Platycodon, Campanula and Asyneuma). A wide range of chemical compounds comprised 109 triterpenes, 8 sterols, 4 polyacetylenes, 21 alkaloids, 14 flavonoids, 14 phenolic acids, 11 phenolic glycosides, 8 phenylpropanoids and 22 other compounds. Pharmacological studies of these compounds have demonstrated immuno-stimulating, anti-inflammatory, anti-asthmatic, apophlegmatic and anti-allergic effects. They have also shown antioxidant, estrogenic, anti-diabetic, hepatoprotective, neuroprotective, antinociception and anti-tumor activities, as well as anti-obesity and cardiovascular effects. In light of traditional knowledge and phytochemical and pharmacological studies summarized, uses of Korean Campanulaceae based on traditional knowledge (for the treatment diseases and conditions of respiratory, pregnancy, childbirth, puerperium, genitourinary, circulatory, musculoskeletal and other systems) have been supported by phytochemical and pharmacological studies.

• Journal of the Korean Society of Radiology
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• v.9 no.2
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• pp.79-99
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• 2015

Participants of this study were students of radiology who were attending colleges or universities located in Daegu and Gyeongbuk. This researcher conducted a questionnaire survey of those students from Feb. 3rd to 21st, 2014. The findings of the study can be summarized as follows. 1. Concerning the knowledge of radiation exposure management, the respondents' scores were highest in two items, or 'Materials based on lead or concrete may shield X-rays' and 'The sexual gland is very sensitive to radiation' and lowest in the item which says' 'Occupational radiation exposure dose should not exceed 20mSv a year in average on a 5-year period basis'. 2. The participants' scores for the attitudes of radiation exposure management were higher in two items, or 'Health examination should be made regularly in relation to radiation exposure' and 'Those who work within the area of irradiation should wear protective clothes' and lowest in the item which says 'Radiation exposure dose should be regularly measured for the calibration of the radiation system'. 3. For the behaviors of radiation exposure management, the surveyed students showed highest scores in two items, or 'When irradiating the patient, the radiator should be behind the protective barrier(plate)' and 'It is needed to receive the education of radiation exposure management regularly' While, their score for a behavior described in the item saying 'Before using the radiation system, it is needed to check whether the machine works normally.

• Journal of Science and Technology Studies
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• v.15 no.1
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• pp.3-43
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• 2015

This essay aims to search for the general tendency and characteristics of scientific citizenship, expert knowledge power, and governance in Korea, followed by the analysis of the citizen's perception survey on science and technology. Also, based on the analysis, we try to outline the state of scientific citizenship, and prospect its future. For this purpose, firstly, we choose 11 issues among 13 issues, categorize them into five sub-fields, such as reproduction technologies, nuclear power, climate change and energy, food risk, and information and communication, and analyze them. Consequently, we can pick out six general tendencies and characteristics of scientific citizenship, expert knowledge power, and governance in Korea. To sum up, we try to look ahead the future of scientific citizenship in Korea.

• Women's Health Nursing
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• v.28 no.4
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• pp.329-337
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• 2022

Purpose: The purpose of this study was to investigate the influence of eHealth literacy, reproductive health knowledge, and self-esteem on early adult women's health-promoting behaviors (HPB). This study was based on Pender's health promotion model as a theoretical underpinning. Methods: Early adult women aged 18 to 35 years (n=165) were recruited by posting advertisements on social network sites for a student club and a faith-based community in Ansan, Korea. Willing individuals were invited to participate in the online survey from June 1 to June 30, 2022. Standardized instruments were used to measure HPB, eHealth literacy, reproductive health knowledge, and self-esteem. General characteristics included income level, perceived subjective health, and internet usage time. The collected data were analyzed using the independent t-test, one-way analysis of variance, Pearson correlation coefficients, and multiple regression. Results: The mean age of the respondents was 21.97±3.87 years. The total HPB score was 120.69, corresponding to a moderate level; and the total scores for eHealth literacy (30.24), knowledge of reproductive health (23.04), and self-esteem (35.62) were higher than the midpoint. The model explained 53.3% of variance in HPB, and self-esteem (β=.48, p<.001) was the most influential factor. Other influential factors were, in descending order, higher economic level, higher subjective health status, greater eHealth literacy, and less internet use time (<2 hours/day). Conclusion: In order to promote the health of early adult women, counseling or programs that positively improve self-esteem appear promising, and eHealth literacy should be considered as a way to promote HPB using information technology.

• Development and Reproduction
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• v.10 no.2
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• pp.85-92
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• 2006

Progesterone(P4) is an important intermediate in the synthesis of androgens and estrogens. Furthermore, P4 itself plays a crucial role in ovulation, atresia and luteinization, and is essential for the continuation of early pregnancy in all mammalian species. In spite of the hormone's physiological importance, the exact action mechanism(s) of P4 in mammalian ovary has not been fully understood yet. In this context, a decades-long controversy regarding the identity of receptors that mediate non-genomic, transcription-independent cellular responses to P4 is presently attracting huge scientific interests. P4 may exert its action in mammalian ovary by several ways: 1) the well-documented genomic pathway, involving hormone binding to so-called classic cytosolic receptor(PGR) and subsequent modulation of gene expression by the ligand-receptor complex as transcription factor. 2) pathways are operating that do not act on the genome, therefore refered to as non-genomic actions. The prominent characteristics of the non-genomic P4 actions are: (i) rapid, (ii) insensitive to transcription inhibitors, (iii) transduced by membrane associated molecules. In particular, the non-genomic P4 actions could be mediated by: (a) classic genomic P4 receptor(PGR) that localizes at or near the plasma membrane, (b) a family of membrane progestin receptors(MPR $\alpha$, MPR $\beta$ and MPR $\gamma$), (c) progesterone receptor membrane component I(PGRMC1), and (d) a membrane complex composed of serpine I mRNA binding protein(SERBP1). The present review summarized these rapid signaling pathways of P4 in the mammalian ovary.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.651-659
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• 2017

Although the need for education on sexually-transmitted-infections (STIs) for adolescents has been increasing, a limited number of adolescents receive STI education. Importantly, the exposure of youth to an STI during their adolescence period can seriously affect their genital health. Smartphones are an innovative medium that can be used to change individual behaviors, especially useful when used to educate adolescents. Therefore, we developed a customized smartphone application for Korean adolescents. The application was based on Dick and Carey's instructional system design model. In this paper, we describe the process for development of the smartphone application, and the strategies we applied to attract adolescents to use the smartphone application. Six experts verified the educational content of the application. The application's easygoing words were chosen to help adolescents understand the topic. Strategies such as cartoon clips, secret chat rooms, buttons changing color from blue to grey, questions and answers, and a repeated-learning function were used to attract Korean adolescents to the application. The smartphone application developed in this study could be used in schools, youth centers, and hospital centers to improve STI knowledge, STI prevention, and STI coping skills.

• Journal of the Korean Society of Radiology
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• v.10 no.6
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• pp.457-468
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• 2016

The purpose of this study was to investigate factors of perception by inpatients of the Medical Examination institutions about exposure to radioactivity at the time of radioactive examination, providing basic information for making educational materials aimed to change their perception. Most of those patients, 72.0% responded that CT was a type of radioactive examination bringing highest exposure to radiosensitivity. Most of the subjects, 63.5% said that a body part most vulnerable to exposure to radiosensitivity was the genital gland at the time of radiosensitivity examination. And most of the participants, or 29.0% responded that they obtained information about radiation from TVs or newspapers. Among the surveyed patients, men were higher in scores for factors of the perception of radiation such as recognition of radiation, harmfulness of radiation, psychological state at the time of radioactive examination, prevention of exposure to radioactivity and necessity of radiation that women were, with statistically significant differences between the two groups. These findings suggest that it is urgently needed to develop an education program which helps patients better perceive exposure to radioactivity and that radiologists should be very careful to reduce the does of that exposure. If patients better perceive radiation, they would be less anxious and less exposed to radioactivity when receiving the radioactive examination.