• Title/Summary/Keyword: 생물전공

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Anti-inflammatory activity and toxicity of the compound K produced by bioconversion (생물전환에 의해 생성된 Compound K의 항염증 및 독성 효과)

  • Kim, MooSung;Shin, Hyun Young;Kim, Hyun-Gyeong;Kang, Ji Sung;Jung, Kyung-Hwan;Yu, Kwang-Won;Moon, Gi-Seong;Lee, Hyang-Yeol
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.6
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    • pp.1466-1475
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    • 2021
  • Compound K (20-O-β-(D-glucopyranosyl)-20(S)-protopanaxadiol) is an active ingredient of ginsenosides. Compound K has been known to produce from biotransformation by β-glucosidase action of human intestinal microbes after oral admistration of ginseng. We have investigated the cytotoxicity of compound K obtained from bio-converted ginseng extract. As a result, compound K showed no significant cytotoxicity in the concentration of 0.001 to 1 ㎍/mL and inhibited the production of TNF-α, MCP-1, IL-6 and NO in RAW 264.7 cells induced by LPS inflamation. In the same concentration, HaCaT cells induced by inflammation with TNF-α and IFN-γ decreased IL-8 production due to compound K treatment. In the brine shrimp lethality assay, the LC50 of compound K was 0.37 mg/mL indicating some toxicity, but the bioconverted product containing 35% compound K showed relatively low toxicity with an LC50 of 0.87 mg/mL. These results suggest that the compound K enriched extract is a potential functional material for acne relief cosmetic products.

Analyzing the Impact of Species on Urban Development Using Meta Population Model (메타개체군 이론을 활용한 도시개발에 따른 생물 종 영향 평가 활용 가능성 분석)

  • Eun Sub Kim;Young Won Mo;Tae Yoon Park;Yoonho Jeon;Jiyoung Choi;Dong Kun Lee
    • Journal of Environmental Impact Assessment
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    • v.32 no.2
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    • pp.61-71
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    • 2023
  • As differences in the impact of each species on a spatial scale occur, analysis at the landscape scale is necessary to evaluate the impact of a development project. In previous studies, the Incidence Function Model (IFM) based on meta population theory was used to analyze the impact of species on the environment that changes according to urban development. However, since the model was required at least 10 occupied areas, it is difficult to use it for species that are difficult to monitor such as endangered species. Therefore, we proposed the Incidence Function Model (IFM) using species distribution model to fill the species data. In addition, we reviewed whether the developed model can be used in environmental impact assessment. As a result of the analysis, the minimum occupancy of Prionailurus bengalensis on urban development decreased to 56.5% and the possibility of survival to 28.7%. We confirmed that It rapidly decreased from the reference points of 230 and 70habitats through analysis of the meta-population capacity according to the decrease in the number of habitats. These results can be assessing the environment impact of each species on habitat loss. And it can support decision-making on the minimum number and area of habitat for species protection. This study is expected to be used as basic data for environment impact assessment on before and after development projects and mitigation measures plans, thereby increasing the effectiveness of reduction plans.

Psychiatry, Is It Now Okay? - Enlarging the Boundary of Psychiatry in the Neuroscience Era (정신의학, 이대로 좋은가?-신경과학 시대에서 정신의학의 영역 확대 방안)

  • Park, Jonghan;Kim, Nam Soo
    • Korean Journal of Biological Psychiatry
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    • v.8 no.1
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    • pp.53-61
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    • 2001
  • The authors, in this paper, addressed a variety of problems and difficulties which Korean psychiatrists should cope with. The surprising development of neurosciences, splitting of neuropsychiatry into neurology and psychiatry, easygoing attitude of psychiatrists, changes in the delivery system of health care and ill-balanced education of psychiatry were listed as causes of or contributors to them. Social bias to psychiatry and regulations from outside are also considered as contributors. Psychiatric education, including medical school, residency training, continuing medical education and psychiatric textbooks, need to be changed in order to enlarge the boundary of psychiatry. Reestablishment of identity of psychiatry and psychiatrist is unavoidable, considering far-reaching new knowledge of neuroscience and gradually invisible borderzone between neurology and psychiatry. The other ways worth while to consider are : the expansion of psychiatrists' activities, development of medical behavioral science to a clinical specialty, creation of new psychiatric subspecialties, and additional training of psychiatric residencies in the primary medical care.

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Applications of Enzyme Immobilized Membranes: A Review (효소 고정화막의 응용에 대한 총설)

  • Ryu, Junghyun;Patel, Rajkumar;Kim, Jong Hak
    • Membrane Journal
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    • v.31 no.6
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    • pp.393-403
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    • 2021
  • Enzymes are important class of catalyst for biotransformation. Stability and reusability of enzymes during the catalysis process is a key issue. Activity of enzyme can be enhanced by its immobilization on a suitable substrate by creation of specific microenvironment. A variety of membranes has been used as substrate due to the biocompatibility and simpler method to tune hydrophilicity/hydrophobicity property of the membrane surface. In this review, polymer membranes including cellulose, polyacrylonitrile (PAN), polydimethylsiloxane (PDMS), polyvinylidene fluoride (PVDF), polyethersulfone (PES) are introduced and discussed in detail. Biodegradation of organic contaminants by immobilized enzyme is an environmental friendly process to reduce the contamination of environment in pharmaceutical company and textile industries. The controlled hydrolysis of oil can be performed in enzyme immobilized membrane bioreactor (EMBR), resulting in reducing carbon emission and reduced environmental pollution. Bioethanol and biodiesel are considered alternative fossil fuels that can be prepared in EMBR.

Cultivation of Pholiota adiposa by Use of Sawdusts and Agricultural By-product Substrates (톱밥과 농산부산물을 이용한 검은비늘버섯(Pholiota adiposa)의 재배)

  • Lee, Sang-Sun;Lee, Jeong-Woo;Cho, Nam-Seok
    • Journal of the Korean Wood Science and Technology
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    • v.30 no.1
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    • pp.72-78
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    • 2002
  • Cultivation of Pholiota adiposa on sawdust media and its mixed substrates with various agricultural by-products was attempted. The composition of each substrates were compared from the viewpoint of cultivation possibilities with the production of Pholiota adiposa. Populus deltoides showed the best production of the mushroom with 795 g, followed by Robinia pseudo-acacia and Quercus acutissima. The mixed sawdust media with 70% of Robinia pseudo-acacia and 30% of Populus deltoides showed the best production of the mushroom with 265 g followed by the mixture of Robinia pseudo-acacia and Populus deltoides with 50% each with 228 g, while the addition of Quercus acutissima showed the negative effect for the production of Pholiota adiposa. Thus, Robinia pseudo-acacia was considered to be an effective amendment for the production of the mushroom. In addition, various kinds of agricultural by-products showed additive effect for the production of the mushroom, too. Therefore, we could concluded that the sawdust of Robinia pseudo-acacia and agricultural by-products can be used to cultivate Pholiota adiposa.

Basic Research for the Efficient Management and Operation of Biosphere Reserves -: A Case Study of the Gwangneung Forest Biosphere Reserve - (생물권보전지역의 효율적 관리·운영방안 마련을 위한 기초연구 -광릉숲 생물권보전지역 사례로)

  • Chan-Young Park;Sung-Jin Yeom
    • Journal of Environmental Science International
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    • v.32 no.6
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    • pp.453-464
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    • 2023
  • To this day, conflicts have intensified between managers who want to preserve biosphere reserves and citizen who want to develop them. Based on this problem, this study seeks to investigate the establishment of a forum for communication between various stakeholders and to promote the economic development of local communities while preserving biodiversity. First, in terms of conservation, the results indicated that Gyeonggi Province and Namyangju City highly valued direct conservation activities in biosphere reserves, whereas Pocheon and Uijeongbu City highly valued indirect conservation functions through management or monitoring. Second, in terms of development, it was found that there were differences in the roles, perceptions and responsibilities with respect to biosphere reserves among the different layers of government: the central government agency, the Cultural Heritage Administration, the metropolitan government, Gyeonggi-do, and the local governments, Pocheon, Namyangju, and Uijeongbu. Third, in terms of logistical support, which serves as a function for communication and practical participation among management entities, the results suggested that it was necessary to establish a comprehensive decision-making organization for efficient management and operation and to provide opportunities for active participation. The study can be utilized as a basic reference for developing efficient communication by management entities in protected areas with similar challenges.

Analysis of Conceptions of Earth System Cycles as Perceived by College Students (대학생들이 인식하는 지구계 순환의 구성 개념 분석)

  • Kim, Yun-Ji;Jeong, Jin-Woo;Wee, Soo-Meen
    • Journal of The Korean Association For Science Education
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    • v.29 no.8
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    • pp.963-977
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    • 2009
  • The purpose of this paper is to identify college students' conceptions of the earth system cycles as learners of earth science education (ESE) and draw educational implications. An eight-week creative story writing project was held with 62 non-science students taking a general course on earth science. Their creative stories were categorized by analyzing the conceptions and types of cycle with a story mapping technique. The cycle conceptions of earth systems were expressed diversely into 32; most of the cycle types were circular and complex, while the others were branch-shaped and linear types that fail to complete the cycles. College students' conceptions of the earth system cycles is biased toward natural-abiotic systems; less than 30% of them are shown to be aware of all three categories: natural-abiotic, natural-biotic, and human systems. It is essential to diversify the content of education on earth system cycles and help learners develop systematic methods of thinking so that they will be able to recognize the impacts of feedback from human activities through ESE.

Influence of Agricultural Water Return flow on Aquatic Ecosystem in Downstream (농업용수 회귀수량이 하천 수생태에 미치는 영향)

  • Lim, Eunjin;Kim, Jonggun;Shin, Yongchul;An, Hyunuk;Nam, Won Ho;Lim, Kyoung Jae;Lee, KwangYa
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.246-246
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    • 2020
  • 최근 우리나라에서 농업용수의 다원적 기능에 대한 공감대가 형성되고 작물생육에 필요한 관개용수로만 인식되던 농업용수의 개념이 농촌생활환경개선을 포함하는 다양한 지역용수로의 포괄적 개념으로 전환되고 있다. 농업용수는 식량생산 이외의 효용을 위한 다원적 기능을 가지며 농촌지역의 각종 생산활동과 생활조건의 유지개선을 위한 농업용수의 다원적 기능에 관한 관심이 증가하는 추세이다. 농업용수에서 발생하는 회귀수는 유역의 용수공급계획, 하천 유황의 예측, 관개용수 사용량 결정, 하천 건전화 방지, 수생생태계 보호 및 생물 다양성 확보 등 농업용수의 효율적 사용 및 환경생태유지를 위해 매우 중요한 역할을 하고 있다. 농업용수 회귀수량은 농업용수 중 하천으로 회귀하는 수량을 의미한다. 본류의 생태 유량 확보에 농업용수 회귀 수량이 기여하고 있으며 본류 하천의 환경 보전 기능을 하고 있다. 또한, 수생태계 보호 및 생물 다양성 확보 등 환경 생태 유지에 매우 중요한 역할을 하고 있다. 하지만 농업용수 회귀수량이 하천 수생태에 미치는 영향 분석 연구는 미흡한 실정이다. 따라서 본 연구의 목적은 대사 저수지 유역을 대상으로 농업용수 회귀 수량이 하류 하천 수생태에 미치는 영향을 정량적으로 평가하고자 한다. 본 연구에서는 회귀 수량은 관개용수량, 배수량, 침투량, 담수심 등 물수지 항목을 논물수지 모형에 적용하여 산정하였으며, 하류 하천의 생태유량 산정을 위해 대사저수지 하류에 위치한 생물측정망 자료를 통해 대표 어종을 선정하였다. PHABSIM 모형을 이용해 모의 대상 지역 특성 자료 및 인근 소하천 생물측정망 자료를 바탕으로 HSI 기반 대표 어종 서식처 환경에서 최적 생태유량을 산정하였다. 이를 통해 추정된 농업용수 회귀 수량에 따른 필요 유량이 어류 서식환경에 미치는 영향을 평가하였다. 본 연구 결과 대사저수지 하류 하천에서 농업용수 회귀수량이 차지하고 있는 기여도 큰 것으로 분석되었으며, 최적 생태유량과 비교한 결과 농업용수 회귀수량이 수생태(어류)에 미치는 영향이 큰 것으로 나타났다. 따라서 농업용수 회귀수량은 하류 하천의 하천유지수량뿐만 아니라 하천 환경생태유지에도 매우 중요한 역할을 하고 있음을 알 수 있다.

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Analysis of the Results of 2002 and 2003 Examination for Appointing Secondary School Science Teachers (2002 및 2003학년도 중등과학교사임용시험 결과 분석)

  • Lee, Yang-Rak
    • Journal of The Korean Association For Science Education
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    • v.24 no.3
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    • pp.532-543
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    • 2004
  • The teacher appointment examination is consisted of a written test, an interview, a demonstration of teaching practices, one's academic record etc. The primary written test(full credit of 100) consists of multiple-choice test of general pedagogy(30%) and constructed response test of science(70%). The science test consists of science education($20{\sim}30%$) and science content($70{\sim}80%$). Five science exams were implemented for appointing general science, physics, chemistry, biology and earth science teachers in 2002 and 2003. The credits alloted to science education domain decreased from $25.7{\sim}30%$ in 2002 to $24.3{\sim}25.7%$ in 2003. The percentage of correct answer was similar between science education and science content domain in 2002, but the percentage of correct answer in science education domain(70.2%) was 29.8% higher than that of science content domain in 2003. Earth science exam almost reached the target mean score of 60 but the other four exams showed the mean scores ranging from 45.0 to 52.7 in 2002 and from 40.1 to 49.6 in 2003. The percentage of high difficulty items(p<40%) was 41.2% in physics and chemistry in 2002, 50% in physics and chemistry, and 45% in biology in 2003. Seventy eight percent of the items showed fairly high discrimination index(r>.30). In addition, the reliabilities of 5 tests were from .79 to .88. In conclusion, it is recommended that the credits alloted to science education domain should be increased up to 30%, and exam difficulties should be lowered to a proper level by making science content items easier.

Potential Applicability of Moist-soil Management Wetland as Migratory Waterbird Habitat in Republic of Korea (이동성 물새 서식지로서 습윤토양관리 습지의 국내 적용 가능성)

  • Steele, Marla L.;Yoon, Jihyun;Kim, Jae Geun;Kang, Sung-Ryong
    • Journal of Wetlands Research
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    • v.20 no.4
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    • pp.295-303
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    • 2018
  • Inland wetlands in the Republic of Korea provide key breeding and wintering habitats, while coastal wetlands provide nutrient-rich habitats for stopover sites for East Asia/Australasia Flyway(EAAF) migrants. However, since the 1960's, Korea has reclaimed these coastal wetlands gradually for agriculture and urban expansion. The habitat loss has rippled across global populations of migrant shorebirds in EAAF. To protect a similar loss, the United States, specifically Missouri, developed the moist-soil management technique. Wetland impoundments are constructed from levees with water-flow control gates with specific soils, topography, available water sources, and target goals. The impoundments are subjected to a combination of carefully timed and regulated flooding and drawdown regimes with occasional soil disturbance. This serves a dual purpose of removing undesirable vegetation, while maximizing habitat and forage for wildlife. Flooding and drawdown schedules must be dynamic with constantly shifting climate conditions. Korea's latitude ($N33^{\circ}25^{\prime}{\sim}N38^{\circ}37^{\prime}$) is comparable to Missouri ($N36^{\circ}69^{\prime}{\sim}N40^{\circ}41^{\prime}$); as such, moist-soil management could prove to be an effective wetland restoration technique for Korea. In order to meet specific conservation goals (i.e. shorebird staging site restoration), it is necessary to test the proposed methodology on a site that can meet the required specifications for moist-soil management. Moist-soil management has the potential to not only create key habitat for endangered wildlife, but also provide valuable ecosystem services, including water filtration.