• Journal of Nutrition and Health
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• v.40 no.5
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• pp.428-434
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• 2007

Cham-dang-gui (Angelica gigas nakai) has been used in traditional Korean medicine to treat hemotological disorders. The purpose of this study is to investigate the hematological effects of water extracts of Cham-dang-gui in rats with anemia induced by iron-free diets. Rats were divided into two groups, a regular diet group (RD) and an iron-free diet group (FeD). The iron-free diet group was then subdivided into the following three treatment groups: saline (1.0 ml/kgBW/day, FeDS), Cham-dang-gui (1.0 g/kgBW/day, FeDA), and iron (iron succinylate 14 mg/kgBW/day, FeDFe) groups. Rats were fed an iron-free diet for 6 weeks to induce iron-deficient anemia, and subsequently underwent the treatments, during which they were fed an iron-free diet for 3 weeks followed by a regular diet for 3 weeks. Body weights of the iron-diet groups (FeDS, FeDA, FeDFe) were lower than that of RD group. The blood levels of Hgb, Hct, MCV, MCH and TIBC were significantly higher in RD and FeDFe groups than those of other groups. The water extract of Cham-dang-gui with iron-free diet has no hematological effects. A regular diet followed by iron-free diets significantly increased blood levels of Hgb, Hct, and MCH.

• Journal of Chest Surgery
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• v.34 no.11
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• pp.875-878
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• 2001

Background: Although sclerotherapy is an established procedure in treating varicose veins, a wide disparity remains in the rates of success. The purpose of this study was to evaluate the effectiveness and complications of sclerotherapy in combination with compression. Material and Method: From December 2000 to September 2001, a combined total of 50 legs in 39 patients with primary varicose veins were treated with sodium tetradecyl sulfate as sclerosant with the empty vein technique. Immediately after the injection, local compression was increased by a cotton wool roll, and additional compression was obtained with class II medical compression hosiery. Patients were evaluated at 5 days, 1 week, 2 weeks, and 6 weeks for degree of improvement and complications. Result: There were 36 women and 3 men ranging in age from 26 to 66 years, with a mean age of 45.3 years. Good sclerosing results were obtained in all patients. Of fifty legs, five had minor complications, two small intravascular clots, two pigmentations, and one compression-related bulla, which needed no treatment. Conclusion: The use of a cotton wool roll for local compression is highly effective, and sclerotherapy in combination with compression is safe and effective in the treatment of varicose veins.

• 동물약계
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• no.36
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• pp.2-3
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• 1997

[ $\cdot$ ]사료내 잔류농약 및 동물용의약품 허용기준 개정(안)에 대한 검토 협의회 개최 $\cdot$동물약사 감시결과 행정처분 내역 홍보 $\cdot$동물약품 품질관리를 위한 보관품 수거 $\cdot$사료첨가용 항생물질제제 함습도 기준 검토 $\cdot$사료첨가용 항생물질 '아보파신제제' 사용 규제 검토 $\cdot$동물용면역증강제 실용화 희망 업체 조사 $\cdot$97년도 상반기 알찬 거래선 지정 $\cdot$97년도 유당 공급선 지정$\cdot$알선 $\cdot$97년도 동물약품 제조용 유당 업체별 배정 $\cdot$$\ulcorner$동물약품 업계의 현황과 과제$\lrcorner$ 제작$\cdot$배부 $\cdot$동물약품 수출 촉진 협의회 개최 $\cdot$유방염 치료용 연고제 색소첨가 협의회 $\cdot$동물용의약품등 편람 제작 및 제품 홍보 안내

• Journal of Periodontal and Implant Science
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• v.33 no.2
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• pp.271-276
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• 2003

Oral melanin pigmentation is common in some races and ethnic groups. The gingivae are the most frequently pigmented intra-oral tissues. Melanin pigmentation is the result of melanin granules, produced by melanoblasts intertwined between epithelial cells at the basal layer of the epithelium. We present one case of melanin pigmentation of the gingiva of 26-year old female. Melanin depigmentation method is applying a 90% phenol solution to deepithelize pigmented areas, gingivectomy, epithelial abrasion, bone denudation, and split thickess flap. We chose epithelial abrasion using round diamond bur. The patient satisfies the result and have almost no pain and discomfort. But repigmentation potential must be noticed to patient.

• The Monthly Diabetes
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• s.212
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• pp.59-61
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• 2007

당뇨병은 발병 후 거의 완치가 불가능한 질환으로 당뇨병의 치료는 고혈당에 의한 증상을 개선, 여러 가지 급성 및 만성합병증을 예방하는 데 그 목적이 있다. 당뇨병 조절 및 합병증 연구 등에서 엄격한 혈당조절을 통해 당뇨병의 만성합병증이 예방되거나 이미 발생된 합병증도 진행이 지연됨이 알려졌으며, 이에 따라 지속적인 혈당조절의 필요성이 더욱 중요해지고 있다. 지속적인 혈당조절을 위한 당뇨병관리의 기준이 되는 지표에는 여러 가지가 있지만 그 대표적인 것으로 공복혈당, 식전혈당. 식후 2시간 혈당, 당화혈색소 등이 있다. 환자들은 어떤 검사가 나의 혈당변화를 가장 정확히 나타내 주는지 궁금할 때가 있다. 또한 혈당검사를 하루 중 언제 측정해야 가장 정확하고, 얼마나 측정해야 하는지도 궁금하다. 여기서는 혈당조절의 지표가 되고 합병증 예방의 가장 기초가 되는 검사의 종류와 검사 시기, 빈도를 알아보고자 한다.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.1
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• pp.172-176
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• 2004

Phototherapy has perpetual history. we can see an instance of it in Yellow Emperor's Canon of Medicine(黃帝內徑) and Laser therapy is a field of Phototherapy being used frequently in the latest time. We treated patients with hyperpigmentation by laser therapy and experimented it's efficacy and studied the means of clinical application in Korean medicine. We report the capabilities of application of laser therapy, based on the Korean medical theories by using resemblance between laser therapy with kyung-rak(經絡) control technique in the line that connects with the past.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.309-310
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• 1998

Visual observation and subjective assessments lack the objective evaluation of laser therapy effects of the epidermal pigmented lesions. In this study, we proposed the two methods; One is CIE(Commission International d'Eclairage) $L^*,\;a^*,\;b^*$ coordinate system($L^*$ : brightness, $a^*$ : red(+) $\sim$green(-) content, $b^*$ : yellow(+) $\sim$blue(-) content), and the other is the relative color difference measurement. And we applied these two methods for quantitative evaluation of the laser therapy effects.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.2
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• pp.109-116
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• 2013

Objective : The purpose of this report is to know the effect of Jibaekjihwang-tang(知栢地黃湯) on progressive pigmented purpuric dermatosis. Methods : We experienced one case of progressive pigmented purpuric dermatosis treated with Jibaekjihwang-tang(知栢地黃湯). We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and purpuras, pruritus and dryness of skin were disappeared. Conslusion : Jibaekjihwang-tang(知栢地黃湯) can be used on the treatment of progressive pigmented purpuric dermatosis.

• Journal of Food Hygiene and Safety
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• v.15 no.2
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• pp.167-172
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• 2000

Lithospermum erythrorhyzon has been used as a red fooddye and traditional Chinese medicine to treat wounds, skin diseases and burns. Platelet activation plays an important role in thrombosis and haemostasis. Here, we studied the inhibition of platelet activation and its active compound from the root of Lithospermum erythrorhyzon. Its ethyl acetate extract inhibited the aggregation of washed rabbit platelets induced by collagen or thrombin. Five naphthoquinone pigments , shikonin , acetylshikonin , is obutylshikonin, $\alpha$-methyl-n-butylshikonin and $\beta$,$\beta$-dimethylacrylshikonin were isolated by means of high pressure liquid chromatography. The structures were determined by comparison of their proton nuclear magnetic resonance spectra. The potency of their inhibition was in the following order : $\beta$,$\beta$-dimethylacrylshikonin$\geq$$\alpha$-methyl-n-butylshikonin>isobutylshikonin>acetylshikonin>shikonin. It is suggested that the size of the aliphatic hydroxy group of shikonin is important for the enhancement of potency.

• The Journal of Korean Academy of Prosthodontics
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• v.36 no.2
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• pp.379-388
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• 1998

본 연구는 악안면보철용 실리콘의 색안정성을 연구하기 위하여 실리콘 재료로 MDX 4-4210 Silicone(Dow Coming. Midland, Mich.)과 A-2186(Factor II, Lakeside, Az)을 사용하고 Mars Violet. Golden Yellow, Red yellow, Raw Sienna등 4종의 색소(Factor II, Lakeside, Az)를 이용하여 시편을 제작한 후 1군은 섭씨5-55도에서 700회 thermocycling하였고, 2군은 10%의 비눗물(Ivory, Proctor & Gamble Inc,. Toronto, Ontario)에 담아 섭씨15-55도에서 700회 thermocycling하였다. 3군은 10%의 비눗물에 담아 75일간 실온에서 보관하였으며 4군은 실온의 암실에 75일간 보관하였다. 5군은 초여름인 6월 중순부터 75일간 햇볕이 잘드는 곳에 위치하였다. 이를 측색색차계(Model TC-6FX, Tokyo Denshoku Co., Japan)를 이용하여 측정하고 색변화를 연구한 결과 다음과 같은 결론을 얻었다. 1. $L^*$값의 경우 모든 실험군에서 대조군에 비해 유의하게 감소하였다. 2. $a^*$값의 경우 대부분의 실험군에서 증가하였으나 Raw sienna, Mars violet색소를 사용한 실험 3.4.5군의 MDX4-4210의 경우 감소하는 경향을 보였다. 3. $b^*$값은 실험1.2.3군의 경우 대부분 감소하였고 실험4.5.군의 경우에서 증가하였으나 3.4.5군의 경우에서 대부분 유의한 차이가 없었다. 4. ${\Delta}E$의 값은 실험군에서 대부분 감소하였으나 4군의 A-2186에서 증가하는 경향을 보였고 실험2군의 Red yellow, Mars violet을 사용한 MDX4-4210에서 비교적 큰 변화를 보였다. 5. $L^{\ast}$값과 a값의 변화량의 합은 A-2186의 경우에서 크게 나타났으나 ${\Delta}E$값의 변화량은 MDX4-4210에서 크게 나타났다. 6. $L^*$값의 변화량의 합은 실험4군에서 크게 나타났으며 $a^*$값은 1군에서, $b^*$값과 ${\Delta}E$값의 변화량의 합은 2군에서 크게 나타났다.