• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.1C
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• pp.21-35
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• 2002

Nowadays, in accordance with increasing expectations of multimedia stream service on the internet, a lot of distributed applications are being required and developed. But the models of the existing systems have the problems that cannot support the extensibility and the reusability, when the QoS relating functions are being developed as an integrated modules which are suited on the centralized controlled specific-purpose application services. To cope with these problems, it is suggested in this paper to a distributed QoS management system on CORBA, an object-oriented middleware compliance. This systems we suggested can provides not only for efficient control of resources, various service QoS, and QoS control functions as the existing functions, but also QoS control real-time negotiation and dynamic adaptation in addition. This system consists of QoS Control Management Module(QoS CMM) in client side and QoS Management Module(QoS MM) in server side, respectively. These distributed modules are interfacing with each other via CORBA on different systems for distributed QoS management while serving distributed streaming applications. In phase of design of our system, we use UML(Unified Modeling Language) for designing each component in modules, their method calls and various detailed functions for controlling QoS of stream services. For implementation of our system, we used OrbixWeb 3.1c following CORBA specification on Solaris 2.5/2.7, Java language, Java Media Framework API 2.0 beta2, Mini-SQL 1.0.16 and the multimedia equipments, such as SunVideoPlus/Sun Video capture board and Sun Camera. Finally, we showed a numerical data controlled by real-time negotiation and adaptation procedures based on QoS map information to GUIs on client and server dynamically, while our distributed QoS management system is executing a given streaming service.

• Journal of Plant Biotechnology
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• v.39 no.4
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• pp.235-241
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• 2012

Sumoylation is a reversible conjugation process that attaches the small ubiquitin modifier (SUMO) peptide to target proteins and regulates a wide variety of cellular functions in eucaryotes. As final step of the sumoylation, SUMO E3 ligases facilitate conjugation of SUMO to target proteins. To characterize the functions of the SUMO E3 ligases in Oryza sativa, we isolated a single recessive rice SUMO E3 ligase, Ossiz1-2 mutant. In addition, we also confirmed the interaction between OsSIZ1/-2 and OsSUMO1, respectively, by using an Agrobacterium-based tobacco luciferase transient expression system. Ossiz1-2 mutant exhibited approximately 20% reduction in growth and developmental units compared with wild type. Especially, number of filled seeds and total seed weight were dramatically decreased in the Ossiz1-2 mutant rice. Thus, these results suggest that sumoylation by the OsSIZ1 as SUMO E3 ligase plays an important role in regulating growth and development in rice.

• Journal of the Korean Geographical Society
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• v.51 no.6
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• pp.799-817
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• 2016

This article aims to reveal the ways in which a "space of difference" is produced and interpret the space as a heterotopic space, drawing the case of Filipino elderly care-givers in Israel. The in-betweens and temporariness of the migrants'experiences in the Israeli society lead to the creation of a heterotopic space. Paying attention to their particular life rhythm as live-in care-givers, namely weekdays-workplace and weekend-flat, this article explores how the migrant care-givers build their own society through a variety of spatial practices and multiple social relations based on the flat. In making the flat a perfect form of a lifestyle for their own, the migrants inscribe their presence in the flat in unique ways for different purposes, in a way different to that which surrounds it. However, the structure of flat not only signifies the migrants' marginality but also reflects the challenging position. The flat has functions in relation to all other space that remains, even if such connection often creates effects of contrast and difference. In this light, the flat is not merely an alienated and circumscibed exotic migrant enclave but a heterotopic space which is dynamically constructed in relation to other sites in the wider societal order.

• Korean Journal of Microbiology
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• v.47 no.4
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• pp.342-347
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• 2011

T cells play a key role in viral infection. However, in patients with chronic hepatitis C virus (HCV) infection, HCV-specific T cells are dysfunctional and impaired in the liver, which is the primary site for HCV replication. There are multiple potential mechanisms for HCV-specific T cell dysfunction including induction of immune inhibitory pathways (program death-1; PD-1, cytotoxic t lymphocyte associated antigen-4; CTLA-4) and immune tolerance induced specific for the liver. However, the interaction between hepatocytes and HCV-specific CD8 T cells has not clearly established. In this study, we confirmed huh (human hepatoma) 7.5 cells expressing HLA (human leukocyte antigen) A2 presented antigen to activate HCV-specific CD8 T cells in HLA A2-restricted manner and expression of PD-L (program death ligand) 1 on huh7.5 cells reduced HCV-specific CD8 T cell activation, suggesting an immune modulatory activity. Loss of HCV-specific tetramer responses following antigenic stimulation correlated with increased caspase-3 activity. In addition, PD-L1 on huh7.5 cells rescued HCV-specific CD8 T cells from apoptosis. Our results suggest that the interaction between PD-L1 and PD-1 can recover the function of HCV-specific CD8 T cells in the liver, which could be applied in therapy of HCV chronic infection.

• Polymer(Korea)
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• v.36 no.1
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• pp.111-116
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• 2012

A functionalization of mesoporous materials with organosilane was carried out via a post-synthesis grafting method and $(n-BuCp)_2ZrCl_2$/methylaluminoxane (MAO) as subsequently immobilized on the functionalized mesoporous materials for ethylene polymerization. Organosilanes having amine, cyano or imidazoline group such as $N$-[(3-trimethoxysilyl)propyl]ethylenediamine (2NS), 4-(triethoxysilyl)butyronitrile (1NCy), 1-(3-triethoxysilylpropyl)-2-imidazoline (2NIm) were used for the surface functionalization of mesoporous materials. In the SBA-15/2NS/$(n-BuCp)_2ZrCl_2$ catalyst preparation, the amount of MAO in feed increased with an decrease in the Zr content of the supported catalyst, and Al content in the supported catalyst increased. The ethylene homopolymerization activity of SBA-15/2NS/$(n-BuCp)_2ZrCl_2$ dramatically increased as the amount of MAO in feed increased. Furthermore, when the immobilization time was 6 hrs, SBA-15/2NS/$(n-BuCp)_2ZrCl_2$ showed the highest activity. The activities of supported 2NS-, 1NCy-, 2NIm-functionalized catalysts decreased in the following order, SBA-15/2NS/ > SBA-15/2NIm/ > SBA-15/1NCy/$(n-BuCp)_2ZrCl_2$. 2NS and 2NIm which have two amine groups per silane molecule were shown to interact with $(n-BuCp)_2ZrCl_2$ strongly compared to 1NCy which has one amine group. Thus, the activities increased with an increase in the nitrogen and the Zr content of the supported catalysts.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.285-295
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• 2021

Sleep plays an important role in maintaining overall human health. There is increasing interest regarding the impact of sleep related disorders on metabolic diseases. Obstructive sleep apnea (OSA) is a common health problem, and in the last decade, the emergence of increasing obesity rates has further led to a remarkable increase in the prevalence of OSA, along with more prominent metabolic diseases. Obesity is the strongest risk factor for OSA. However, OSA is also known to cause obesity, suggesting an interaction between OSA and obesity. Although the underlying mechanisms leading to OSA-induced metabolic diseases are probably multi-factorial and are yet to be fully elucidated, the activation of inflammation and oxidative stress and the dysregulation of appetite-regulating hormones have emerged as important pathophysiological components of metabolic dysfunction and obesity observed in patients with OSA. Here, we will review the current state of research regarding the association of OSA with metabolic diseases and the possible pathophysiological mechanisms by which OSA could lead to such diseases. This will enhance our understanding of the potential interactions between OSA and obesity and between OSA and metabolic dysfunction.

• Therapeutic Science for Rehabilitation
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• v.10 no.3
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• pp.43-56
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• 2021

Objective : The objective of this study was to present the components of frailty by organizing the definitions of frail elderly and analyzing the tools used to screen them. Methods : This study searched for articles at involved frailty screening assessments in the elderly. Databases including CINAHL, Embase, Medline Complete, and PubMed were searched. The search terms were "assess" AND "frailty" AND "screening" AND ("frail elderly" OR "elderly"). Results : A total of 539 articles were identified by the search and 11 articles were selected. Frailty occurs due to the depressed function of multidimensional factors, and a frail elderly person is defined as one at high risk of health degeneration, functional impairment, and occurrence of disability, and having a high level of threat to life. Seven tools were selected from 11 articles. The most frequently used tool was the frailty phenotype, which was used in five articles (45.4%). The identified components of frailty were physical, activity participation, nutrition, psychological, social, overall health, and age. Conclusion : The results confirmed the definition and components of frailty. This study is expected to contribute to the future development of standardized evaluation tools for screening frail elderly individuals and intervention programs for the management of the frail elderly.

• Journal of the Korea Computer Graphics Society
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• v.28 no.5
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• pp.1-11
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• 2022

Game engines have the advantage of enabling efficient content production, such as reducing development time, with minimal visual quality guarantees and support for multi-platforms. Recently, game engines have provided various functions that can easily, quickly, and effectively produce immersive content using virtual reality (VR) HMD. Therefore, this study conducts a comparative study on the development environment in VR content production using Oculus Quest 2 HMD, focusing on Unity and Unreal game engines, which are widely used in the content production industry, including games. First, we compare the basic setup process of building a development environment using Oculus Quest 2 HMD and a dedicated controller based on a VR template project that includes the minimum functions and settings provided by each engine. Next, we present a simple experience environment that can interact in a virtual environment and compare the development environment to use a dedicated controller and the process of building a development environment that directly utilizes hands through the hand tracking function provided by Oculus Quest 2. Through this process, we will understand the basic process of building a VR development environment, and at the same time, we will check the characteristics and differences of the engine and use it as a research that can be applied to various immersive content production.

• Journal of the Korea Computer Graphics Society
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• v.28 no.3
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• pp.91-100
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• 2022

This study proposes the metaverse content production pipeline using ZEPETO World, one of the representative metaverse platforms in Korea. Based on the Unity 3D engine, the ZEPETO world is configured using the ZEPETO template, and the core functions of the metaverse content that enable multi-user participation such as logic, interaction, and property control are implemented through the ZEPETO script. This study utilizes the basic functions such as properties, events, and components of the ZEPETO script as well as the ZEPETO player which includes avatar loading, character movement, and camera control functions. In addition, based on ZEPETO's properties such as World Multiplayer and Client Starter, it summarizes the core synchronization process required for multiplay metaverse content production, such as object transformation, dynamic object creation, property addition, and real-time property control. Based on this, we check the proposed production pipeline by directly producing multiplay metaverse content using ZEPETO World.

• Journal of the Korea Society of Computer and Information
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• v.27 no.6
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• pp.157-165
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• 2022

The purpose of this study was to determine whether unstable surface core exercise is more effective than stable surface core exercise on improving functional movement and balance and reducing pain in sedentary female workers with backpain. Participants were randomly assigned to an unstable surface core exercise(UEG; n=10) or a stable surface core exercise(SEG; n=10) group. They participated in the given exercise for 8 weeks. FMS, Y-Balance and VAS were measured before and after the participation in exercise, which were subjected to a repeated-measures ANOVA. In the case of a significant interaction between time and group, paired sample t-tests were conducted for a post hoc analysis within each subject group. Results indicated that FMS of the UEG had a significant effect on HS (p<.01), ASLR (p<.05) and TS(p<.001), but not for other variables. YBT did not show a significant effect for any variable (AT, PL, PM, TS), although the main effect of time was significant in both subject groups. VAS had a significant effect only in the UEG(p<.001). Our findings indicate that compared to SEG, UEG is more effective for improving functional movement and reducing pain, but not for improving balance, in sedentary female workers with backpain.