• Korean Journal of Environmental Agriculture
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• v.3 no.2
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• pp.55-61
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• 1984

농업(農業)은 동식물(動植物)을 대상으로 하는 응용생태학(應用生態學)의 한 분야(分野)로 그의 발전과정(發展過程)은 환경(環境)과 밀접(密接)한 관계가 있다. 환경조건(環境條件)의 다양성(多樣性)은 대상생물(對象生物)의 종류(種類)를 풍부하게 하고 순화(馴化)된 생물(生物)의 사양(飼養) 과정에서 다양(多樣)한 농업형태(農業形態)를 발전시켰다. 생웅계(生熊系)는 자연(自然)의 한 단위로 구성요소(構成要素)들은 기능적(機能的)으로 통일성(統一性)을 유지하고 있다. 농생태계(農生態系)는 생산(生産)을 목표(目標)로 하는 동식물(動植物)을 중심(中心)으로 하는 생태계(生態系)로 자연생태계(自然生態系)와 기본적(基本的) 성질(性質)은 동일하나 인위적(人爲的) 요소(要素)가 크게 작용하고 있는 특리(特異)한 생태계(生態系)이다. 작물(作物)이나 가축(家畜)은 수천년에 걸친 생산력(生産力)의 증대(增大)를 목표(目標)로 인위적(人爲的)인 선발을 거친 것으로 자연조작하(自然條作下)에서 심한 경쟁(競爭)을 거치면서 진화(進化)한 야생생물(野生生物)들에 비하면 선천적(先天的) 포약성(胞弱性)을 갖고 있어 인간(人間)의 보호(保護)(에너지보조(補助))를 필요로 하고 있다. 농생태계(農生態系)는 공간적(空間的) 격리(隔離)와 구성종(構成種)의 단순화(單純化)로 공간적(空間的) 연쇄성(連鎖性)과 종다양도(種多樣度)가 큰 자연생태계(自然生態系)에 비하면 외적(外的) 충격에 대한 내부적(內部的) 완충능력(緩衝能力)이 약하다. 더우기 농생태계(農生態系)는 시간적(時間的) 연속성(連續性)이 없어 극상천이(極相遷移)단계에 달할 수 있는 시간적(時間的) 여유가 없어 생물상호간(生物相互間)의 관계는 초기(初期) 천이(遷移)단계의 특성(特性)인 종다양도(種多樣度)가 낮고 직선적(直線的)이고 단순(單純)한 먹이연쇄성(連鎖性)을 갖고 있다. 생물군집(生物群集)의 천이진행(遷移進行)에 따르는 종다양도(種多樣度)의 증가(增加)는 생물군집내(生物群集內) 현재량(現在量) 증가와 더부러 먹이 연쇄상(連鎖相)을 직선상(直線狀)에서 망상(網狀)으로 변화시키고 주된 물질(物質)${\cdot}$유전회로(流轉回路)를 포식(捕食)먹이 연소회로(連銷回路)에서 부식(腐食)먹이연쇄회로(連鎖回路)로 전환시켜 생태계(生態系)의 물질(物質)은 생태군집내(生態群集內)에 보존(保存)하는 능력(能力)을 증대(增大)시키고 토양(土壤)의 물리(物理) 화학적성질(化學的性質)을 개선하여 계내(系內) 물질(物質)의 유실(流失)을 억제하기도 한다. 농생태계(農生態系)는 생산성(生産性)의 증대(增大), 관리(管理)의 편의(便宜) 기타의 이유(理由)로 구성종수(構成種數)를 인위적으로 제한(制限)하고 관리(管理)를 통하여 발아(發芽), 생장(生長), 개화(開花)등 여러가지 생물학적(生物學的) 현상을 극도로 균질화(均質化)시키고 있어 어떤 생육단계(生育段階)의 생물(生物)이 넓은 면적(面積)에 동시에 존재하게 되는데 이것은 외적조건(外的條件)의 변동(變動)에 대한 감수성(感受性)을 증대시킨다. 이와 같은 자연생태계(自然生態系)와 농생태계(農生態系)의 생태학적(生態學的) 특성(特性)에 관한 이해(理解)와 인식(認識)은 농생태계(農生態系)의 생산성(生産性) 증대(增大)와 영구적(永久的) 유지(維持)를 위한 합리적(合理的) 관리(管理)를 위한 기본(基本)이 될 것이다.

• Journal of Gifted/Talented Education
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• v.20 no.1
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• pp.369-388
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• 2010

A Discourse Analysis tool has been developed and has been applied in the cooperative group inquiry activities in order to derive the characteristics of elementary gifted students in science. We recorded and videotaped the whole group problem-solving processes where 4 elementary students worked together to solve given problems as a group for one year in a gifted education center attached to a university in Seoul. We analyzed recorded discourses using systemic functional linguistics with a focus on the structure of information and topic. The discourse analysis tool was developed with the cooperation of science education and gifted education experts. In discourse analysis, we focused on meaning development processes rather than grammatical analysis. Through application of newly developed discourse analysis tool, we confirmed that the tool is useful in understanding the characteristics of science-gifted elementary students. We also founded that the interaction between students has significant effects on problem-solving processes by comparing two students who showed contradictory features in the share of dialogue. In addition, the result suggested that we need to provide students with proper training for ways to communicate with others for effective science-gifted instruction.

• The Korean Journal of Pharmacology
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• v.29 no.1
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• pp.73-83
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• 1993

In order to examine the effect of ${\beta}-estradiol$ on the cell growth, using a primary rabbit kidney poximal tubule cell culture system. We investigated the effect of ${\beta}-estradiol$ on alpha 1 (IV) collagen and ${\beta}-actin$ mRNA levels from primary rabbit kidney cell cultures, and also the effects of 3 growth factors and ${\beta}-estradiol$ supplementation on the growth of primary rabbit kidney proximal tubule cells in the serum-free medium. 1 nM of ${\beta}-estradiol$ showed a sizable potentiation effect on the growth of the proximal tubule cell in serum-free medium, but higher concentration (> 10 nM) of estradiol indeed inhibited the growth. In the absence of hydrocortisone as a growth supplement in serum-free medium, ${\beta}-estradiol$ caused to potentiate the growth of the cell. In the presence of hydrocortisone, ${\beta}-estradiol$ also potentiated the growth of the proximal tubule cells. According to the Northern analysis, ${\beta}-estradiol$ increased the level of ${\beta}-actin$ mRNA, although mRNA level of the alpha I(IV) collagen was not changed significantly.

• Journal of Digital Convergence
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• v.18 no.8
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• pp.133-149
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• 2020

The purpose of this study was to investigate the effect of perceived risk on continuous usage intention of Internet primary banks and to verify moderating effects of acceptance factors affecting customers' acceptance of Internet primary banks on the relationship between perceived risk and continuous usage intention. The study aims to find ways to cope with perceived risk and strategic measures of intention in order to increase the intention to continuous usage intention of Internet primary banks. For the analysis, interaction effect were conducted among a total of 457 surveys. As a results, First, perceived risks, acceptance factors and continuous usage intention of the customers of Internet primary banks were significantly correlated. Second, the types of perceived risks which have a significant effect on continued usage intention of Internet primary banks were found to be perceived financial and functional risks. Third, respect to moderating effects of moderator variables, usefulness was found to have a significant moderating effect on the relationship between perceived security risk and continuous usage intention. In addition, ease of use was shown to have a significant moderating effect on the relationship between each type of perceived risks and continuous usage intention. This study attempted to explore and seek strategies to reduce perceived risks and strategic plans for acceptance factors to increase continuous usage intention of Internet primary banks.

• KSBB Journal
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• v.19 no.2
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• pp.113-117
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• 2004

The effect of ultrasonification on immuno-stimulatory activities of the extracts from Ephedra sinica Stapf and Rubus coreanus Miq. was observed by the growth of human immune cells. The extraction yields from water extracts and water extract with ultrasonification at 40$^{\circ}C$, 60$^{\circ}C$ and 100$^{\circ}C$ were compared. The highest yield was observed enhancement ratio 2.34% in the extract at 40$^{\circ}C$ with ultrasonification. The growth of human T-cell was increased up to 13.8${\times}$10$^4$ viable cells/$m\ell$ in adding 1.0 g/L of the ultrasonification extracts. The treated extracts increased the specific secretion of TNF-${\alpha}$ up to 10.5${\times}$10$\^$-4/ pg/cell. It was suggested that of the extracts on water the extraction yield with ultrasonification compared improved the extraction with ultrasonification of low than.

• Archives of design research
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• v.17 no.3
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• pp.133-146
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• 2004

Diagrams have been deeply and widely used for supporting effective communication relating to design information and knowledge in most design fields. The results show that their role expands to "developmental design material" increasing the principle and method of design process. It's recent trend that Digital-Diagrams are aggressively used in multimedia design fields such as web contents, interactive movies and DVD Titles in order to support user's information understanding more effectively and to stimulate user's participation in information acquiring process. This study aims to clarify the essence of digital diagram corresponding to infographic material in multimedia design and application of multimedia contents development process . This study purpose leads to argue the substance of Digital-Diagrams as one of infographic types and identity of Digital-Diagrams which is relatively compared to existing Diagrams. Eventually, this study examines the application issues of Digital-Diagrams in multimedia design process. Regarding the identity of Digital-Diagrams, they are functionally utilized depending on hypertext based on language forms and interactivity based on graphical forms as core attributes. Therefore, they semantically enlarge user s information understanding by segmenting hierarchy of information expression and rather support user s acquisition of information control ability. Relating to multimedia design process, Digital-Diagrams are used by information designers and navigation designers as method for ‘modeling for realization based on information acquisition support for information-users. Especially, the study results show that the applications of Digital-Diagrams are performed for information representing methods for information designers and embodiment of useful functional factors of interface for navigation designersgation designers.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.18-23
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• 2018

FPSO consists of topside modularized plants for production of crude oil, and hullside structures that serve as support for the topside and storage of produced crude oil. The structural behavior of the FPSO topside module and its supporting hull depends on the interface structure that connects them, and the interface structure consists of a combination of individual unit support structures called Module Support Seat (MSS). Types of interface structures are various and, accordingly, the basic design of the FPSO topside module structure is greatly influenced, so various design methods should be considered from the initial design phase. Structural design of FPSO topside module requires consideration of the number of MSSs, connection type, and structural analysis options such as the range of finite element models, load conditions, and boundary conditions for verification of structural strength. In this study, the comparison combination cases for the above considerations were derived and the strength evaluation was performed, and the structural behavior characteristics of the topside module were compared and analyzed through a detailed review of the analysis results. The results of this study are considered to be a good reference for designing a more reliable topside module structure.

• Journal of Life Science
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• v.28 no.12
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• pp.1432-1437
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• 2018

Clara cell secretory protein (CCSP) plays an important role in protecting the lungs from inflammation. This research focuses on identifying the cis-element for binding the repressor of CCSP gene expression. A DNase I footprinting experiment revealed three protected regions between -812 and -768 bp (45 bp) of the mCCSP promoter. One motif (D3: GCCTGGGAA) was 100% conserved across rat, hamster, and human. The addition of excess amounts of the D3 motif exhibited high competition within that 45 bp range in an electrophoretic mobility shift assay. However, when mutated D3 ($G{\underline{AA}}TG{\underline{TT}}AA$) was used, the competition was significantly reduced. This demonstrates that the D3 motif within that 45 bp region of the mCCSP promoter is an important site for the protein-DNA interaction. Transient transfection assays with -756 Luc resulted in highly decreased expression of CCSP than those with -812 Luc, suggesting that the 45 bp could function as a binding site for the repressor. Co-transfection of KLF4 exhibited significant repression of the -812 Luc but not the -768 Luc which clearly shows that KLF4 might function as a repressor for the CCSP gene and also suggests that the D3 motif is strongly involved in the binding of KLF4. In addition, when anti-KLF4 antibody was added, super-shifted bands were observed. This result demonstrates that KLF4 could function as a repressor by binding to this 45 bp region of the CCSP promoter and that the D3 motif might be involved in the specific binding of KLF4.

• Science of Emotion and Sensibility
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• v.24 no.2
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• pp.39-48
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• 2021

According to International Associating for the Study of Pain (IASP) definition, neuropathic pain is a disorder characterized by dysfunction of the nervous system that, under normal conditions, mediates virulent information to the central nervous system (CNS). This pain can be divided into a disease with provable lesions in the peripheral or central nervous system and states with an incorporeal lesion of any nerves. Both conditions undergo long-term and chronic processes of change, which can eventually develop into chronic pain syndrome, that is, nervous system is inappropriately adapted and difficult to heal. However, the treatment of neuropathic pain itself is incurable from diagnosis to treatment process, and there is still a lack of notable solutions. Recently, several studies have observed the responses of CNS to harmful stimuli using image analysis technologies, such as functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and optical imaging. These techniques have confirmed that the change in synaptic-plasticity was generated in brain regions which perceive and handle pain information. Furthermore, these techniques helped in understanding the interaction of learning mechanisms and chronic pain, including neuropathic pain. The study aims to describe recent findings that revealed the mechanisms of pathological pain and the structural and functional changes in the brain. Reflecting on the definition of chronic pain and inspecting the latest reports will help develop approaches to alleviate pain.

• Journal of Nutrition and Health
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• v.55 no.5
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• pp.523-532
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• 2022

Vitamin C is an important physiological antioxidant which neutralizes reactive oxygen species (ROS) and reduces the oxidative stress in the body. Although it has been associated with various diseases, few studies have reported the dose-response relationship between vitamin C intake, storage and functions in the body, including its antioxidant function. The criteria to establish the Dietary Reference Intakes for Koreans (KDRIs) for vitamin C were based on the changes in plasma concentrations and saturation of leukocytes according to intake levels and the effects on antioxidant capacity and risk of metabolic diseases. When establishing the 2020 vitamin C KDRI, while there was no change in the criteria from those of 2015, the reference values were recalculated and revised to reflect changes such as the new standard weight by age. As the number of people consuming dietary supplements has increased over the last decade, only about 10% of adults consume less than the average total vitamin C, but the proportion of adolescents and elderly who consume less than the average is high. On the other hand, as the intake of vitamin C supplements increases, the proportion of people consuming excessive vitamin C is also increasing. There is a body of opinion that it is necessary to establish a vitamin C KDRI for smokers or people with chronic diseases such as the metabolic syndrome, but these standards have not been established due to the lack of supporting scientific evidence. As a result, studies to establish vitamin C KDRI for Korean smokers and patients with the metabolic syndrome, as well as studies on the excessive intake of vitamin C due to supplementation and interactions with other nutrients, are needed.