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Is GMO Safe? (A Perspective of Plant Biotechnology in Korea)

  • Song Pill-Soon
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2004.05a
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    • pp.35-38
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    • 2004
  • 1950-1960 년대의 녹색혁명은 1970년 Nobel 평화상수 상자 Norman Borlaug가 주도했었다. 제1 녹색혁명은 지구상의 가장 큰 문제점중의 하나인 기아를 해결하는지 크게 일조하였다. 많은 사람들을 굶주림으로부터 해방시켰지만 굶주리는 사람보다 더 많은 사람들이 매일 태어나고 있고, 지구의 인구증가는 지금까지 계속되고 있다. 언제까지 인구증가가 계속될 것인지, 인구증가에 따른 식량자원의 증가도 비례할 것인지는 오래전부터 인류의 관심의 대상이 되어 왔고, 자연스럽게 지구의 기아를 해결하는 제2의 녹색혁명은 과학자들의 연구를 집중시키는 결과를 낳게 되었다. 1980 년대에 미국 Monsanto 회사에서 유전공학적으로 개발한 Roundup-Ready 제초제저항성 및 Bt-살충 농작물을 선보이면서 제2의 녹색혁명이 시작되었다고 볼 수 있겠다. 이렇게 제2의 녹색혁명은 유전공학에 의한 CMO 식물$\cdot$작물에 의해 시작되었다. Monsanto 회사는 살충제 RoundUp 제초제 저항성 옥수수, 콩, 목화, Canola (유채꽃, rape seed) 등을 개발하여 이미 상업화하였다. 1960년대 쌀의 녹색혁명도 유전적으로 벼집이 짧은 품종에 의해 이루어졌다. 최근에 개발된 GMO "Golden Rice"는 비타민 A와 철분의 함량을 대폭 증대 시켜 세계 영양결핍 아동들의 건강과 시각을 향상시킬 것으로 기대되는데, "Golden Rice"는 제1회 금호국제과학상 수상자인 Potrykus (스위스공대) 교수가 개발하였다. 그러나 현재까지는 그 보급에 많은 장애물이 있다. 특히 GMO의 환경과 건강에 대한 안전성을 의심하는 사람들이 많다. 제2의 녹색혁명의 또 다른 분야는 식물의약 분야이다. GMO 개발에 적용되는 기술을 이용하면 taxol 같은 항암제, carotene 같은 항산화 영양제 등의 대량 생산이 가능해진다. 식물은 화학적 합성이 아주 까다로운 약제물질 등을 천연상태에서 합성하고 있기 때문이다. 또 식물은 lipoxygenase 효소계가 있어서 마치 천연물 석유제조공장과 같은 제조공정 capacity를 가지고 있다. 그러면 식물/식품 GMO는 안전한 것인가? 아니, KBS의 한 사회자가 말했듯이, 그리고 많은 소비자들이 믿는 것처럼 GMO는 위험한가? GMO에 대한 일반 사람들의 공포감은 Green Peace 당원들뿐만 아니라 일부 과학자들에 의해서도 조장되고 있다. 이러한 분위기 속에서 GMO에 의한 제2 녹색혁명은 Africa 대륙에서의 제1 녹색혁명이 지금도 지연되는 것과 같다고도 볼 수 있다. GMO의 환경에 대한 악영향은 과대 선전되어있는 것이 아닌가? 마치 GMO가 화학비료, 농약제보다 더 위험하다고 믿는 사람들도 많다. 나는 이러한 GMO 공포증이 과학적으로 그리고 "Risk Assessment"의 견지에서 볼 때 그 근거가 희박하다고 보여주는 몇 몇 실험 및 경험 사실들을 인용하려 한다. 그리고 올바른 Risk Assessment야 말로 한국의 21세기 BT 산업을 경쟁력 있게 하고 국민 년 소득 2만불 달성에 중요한 기여를 하게 될 것이라고 생각한다. 한국은 농토가 적고 천연자원이 빈약하다. GMO는 21세기의 생존 경쟁 산업이다. 제2의 녹색혁명은 얼마든지 가능하며, 한국은 부족한 농토와 빈약한 자원에도 불구하고 능력 있는 인적자원이 풍부하여 GMO 개발 연구에 국제적 경쟁력을 키울 수 있다. 그러나 GMO에 대한 논쟁만 하고 있으면 이미 때가 늦는다. 미국은 이미 GMO-BT 시장을 거의 완전 독점했으며, 타국에서의 논쟁과 불합리적으로 엄격한 GMO 관련 규정을 조장하고 환영한다.

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Quality Changes of Brined Baechu Cabbage Prepared with Low Temperature Stored Baechu Cabbages (저온 저장 생배추를 이용하여 제조한 절임배추의 저장기간 중 품질 특성의 변화)

  • Jeong, Ji-Kang;Park, So-Eun;Lee, Sun-Mi;Choi, Hye-Sun;Kim, So-Hee;Park, Kun-Young
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.3
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    • pp.475-479
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    • 2011
  • Although the storage period of raw baechu cabbage could be 2 months at $0{\sim}2^{\circ}C$, 1 month was appropriate considering the quality of the baechu cabbage, waste ratio, and storage cost. The polyethylene container was the most efficient storage container among polypropylene box, polypropylene net and polyethylene container. pH of a brined baechu cabbage using raw baechu cabbage was 4.0~4.3 after 8 weeks and its total bacteria and lactic acid bacteria counts were $10^7$ cfu/g, and textural property (springiness) lower than 50% was at 8th week of storage at $0{\sim}2^{\circ}C$ and thus its storage period was limited to 8 weeks. When brined baechu cabbage was prepared by raw baechu cabbage stored for 1 month at $0{\sim}2^{\circ}C$, its pH, microorganism counts and springiness showed similar trends to the brined cabbage using raw baechu stored for 0 month. However, its rates of change were faster than the brined baechu cabbage using the raw baechu, and the storage period was limited to 6 weeks. Brined baechu cabbage using the raw cabbage stored for 2 months and its storage period was limited by about 4 weeks judging by its indicated quality characteristics.

Synthesis and Reactions of Organoruthenium(Ⅲ) Complexes (새로운 3가 유기루테늄 착물의 합성과 반응)

  • Lee Dong-Hwan;Kim Hag-Gu;Seo Dae-Ryong;Kim Byung-Soon
    • Journal of the Korean Chemical Society
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    • v.37 no.1
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    • pp.98-104
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    • 1993
  • The paramagnetic organoruthenium(III) complexes $({\eta}^5-C_5Me_5)RuCl_2(PR_3) (PR_3 = PMe_3,\;PEt_3,\;PiPr_3,\;PCy_3,\;PMe_2Ph,\;PMePh_2,\;PPh_3,\;P(p-C_6H_4CH_3)_3$, DPPE, DPPB, Py) (2a∼2k) were synthesized by the reaction of $[({\eta}^5-C_5Me_5)RuCl_2]_2$ (1) with 1 equivalent of the corresponding phosphines $(PR_3)$. The effective magnetic moment ((${\mu}_{eff} = 1.65∼2.07 B.M.$)) derived from the magnetic susceptibility measurements of the complexes (2a∼2k) were consistent with the presence of a "single" unpaired electron in the molecule. Treatment of dichlororuthenium (III) complex ({\eta}^5-C_5Me_5)RuCl_2(PR_3)$ (2) (i) with KBr in acetone afforded the dibromoruthenium (III) complex $({\eta}^5-C_5Me_5)RuBr_2(PR_3) (PR_3 = PPh_3)$, (ii) with sodium amalgam in diethylether led to the bis(phosphine) derivatives $({eta}^5-C_5Me_5)RuCl(PR_3)_2 (PR_3 = PMe_3,\;PMePh_2)$, and (iii) with carbonmonoxide gave to the carbonyl derivatives $({\eta}^5-C_5Me_5)RuCl(PR_3)(CO) (PR_3 = PMe_3,\;PPh_3)$.

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The Effect of Action Observation Training on Dexterity of Affected Upper Extremity Motor Function and ADL in Stroke Patients (과제지향적 동작관찰훈련이 뇌졸중 환자의 환측 상지기민성과 일상생활활동에 미치는 영향)

  • Eom, Sook;Kim, Su-Kyoung
    • The Journal of Korean society of community based occupational therapy
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    • v.3 no.1
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    • pp.55-66
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    • 2013
  • Objective : The purpose of present study was to determine effects of task oriented action observation training on dexterity of upper limb function after stroke. Training was progressed to imitation and intensive training after observation to required action in ADL. Method : 15 stroke patients were selected and one group pretest-posttest design was applied. Targets observed performance actions of task orientated task through a video and limitated action repeatedly, Training was performed 3 times a week and 20~30 minutes for each round for 3 weeks. Manual function test and 10-second test and Box and block test were performed for a dexterity of upper extremity motor function, Modified Barthel index and Motor activity log were performed for ADL. Result : After the training, a dexterity of affected upper extremity motor function of the target showed significant difference between before and after intervention, ADL showed significant improvement between before and after intervention. Conclusion : Task orientated Action observation lead a positive effect of recovering a dexterity of upper extremity motor function and ADL. Therefore, this study suggest a action observation training as one strategy of an intervention type of th e occupational therapy.

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Effects of Robot-assisted Therapy on Function of Upper Extremity in Stroke Patients (로봇보조(Robot-assisted) 치료가 뇌졸중 환자의 상지기능에 미치는 영향)

  • Hwang, Sun-Jung;Yoo, Doo-Han
    • The Journal of Korean society of community based occupational therapy
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    • v.3 no.1
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    • pp.33-42
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    • 2013
  • Objective : The purpose of this study is to assess effects of Robot-assisted therapy on function of upper extremity in stroke patients. Method : A total of 11 patients suffered from stroke participated in this study. Inpatients of 4 people and outpatients of 7 people divided by 12 months conducted Robot-assisted therapy for 5~6 weeks. Therapists selected appropriate exercise mode to patients, and patients Patients performed the reaching exercise was repeated with looking monitor provided 3-dimensional feedback. Before and after treatment of upper extremity functions was compare by Wolf Motor Function(K-WMFT), Box & Block Test(BBT), Dynamometer, average execution time. Result : Grip power, K-WMFT, BBT, average performance times were promoting in all subjects, and only showed statistically significant changes in outpatients. But outpatients did not show statistically significant changes in inpatients. Conclusion : Robotic-assisted therapy in stroke patients have a positive impact on upper extremity function that could confirm that. In the future, Robots-assisted therapy is expected to be useful for stroke patients in the area of occupational therapy.

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The effects of continuous and intermittent compressive pressure on alkaline phosphatase activity of Periodontal Ligament cells (지속적 및 간헐적 가압력이 치주인대 배양세포의 Alkaline Phosphatase 활성도에 미치는 영향)

  • Kwon, Suk-Yee;Bae, Seong-Min;Kyung, Hee-Moon;Sung, Jae-Hyun
    • The korean journal of orthodontics
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    • v.27 no.4 s.63
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    • pp.599-605
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    • 1997
  • The propose of this study was to evaluate the effect of cellular activity on PDL cells dependent on intermittent and continuous compressive force by determining the alkaline phosphatase activity. An intermittent and continuous compressive forces were applied on PDL cells at the confluent stage. The alkaline phosphatase activity was measured on control and experimental groups every 24, 48, 72hours. The experimental group were consist of continuous and intermittent compressive group which were compressed by $300g/cm^2$ of diaphram pump. The intermittent compressive group was connected by timer which was worked on 10 minutes and off 10minutes. The results were as follows ; 1. The alkaline phosphatase activity of intermittent compressive group was lower than control group at 24 hours(P<0.05). 2. The alkaline phosphatase activity between each groups showed no significant differences at 48hours. 3. The alkaline phosphatase activity of continuous compresssive group was significantly higher than control group at 72 hours(P<0.01).

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Exploration of Optimum Retention of Antibacterial Agents in Functional Packaging Paper (항균 포장원지내 항균소재의 최적 정착법 탐색)

  • Kim, Chul-Hwan;Kim, Jae-Ok;Jung, Jun-Ho;Cho, Sung-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.2
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    • pp.298-305
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    • 2005
  • Antimicrobial packaging paper was prepared with a powder-type botanical antimicrobial agent from grapefruit seed extract (BAAG) and zeolite according to TAPPI standard method. The functional fillers containing BAAG fixed to CaCO$_3$ and zeolite were well retained in the fiber network by a retention aid such as cationic polyacrylamide, which was ascertained by the ash contents of paper and the SEM microphotographs. With addition of the functional fillers to paper, tensile strength and burst strength of the paper decreased by interference of the functional fillers with interfiber bonding but bending stiffness and tear strength increased by improved elastic modulus of paper and delayed transfer of tearing energy. Finally, it was confirmed that the antimicrobial packaging paper might be able to be used to make packaging bags and corrugated containers due to the minor deterioration of strength properties.

Artificial Rearing of Red-striped Golden Stink Bug, Poecilocoris lewisi(Hemiptera : Scutelleridae) on Peanut : Developmental Characteristics, Host Plant and Oviposition Preference (땅콩 급여에 의한 광대노린재(Poecilocoris lewisi)의 인공 사육 : 발육 특성, 기주 및 산란선호성)

  • 김남정;설광열
    • Korean journal of applied entomology
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    • v.42 no.2
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    • pp.133-138
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    • 2003
  • To establish the successive rearing of red-striped golden stink bug, Poecilocoris lewisi Distant, developmental characteristics, host plant and oviposition preference were investigated. Raw peanuts were supplied to the insect as a substitute food at 25$\pm$$1^{\circ}C$, 60$\pm$5% R.H. and under 16Lㆍ8D photo regimen. Total developmental period was 48 days: 8.2$\pm$0.4, 5.4$\pm$0.2, 8. $\pm$0.5, 6.4$\pm$0.4, 7.4$\pm$0.3 and 12.6$\pm$0.8 days for egg, first though fifth instar, respectively. The instar survival rate was 57.1% and the sex ratio was estimated to be 53 : 47 (male : female). Adult longevity was on the average 30.8 in male and 35.4 days in female, respectively. Egg of P. lewisi was globular ($\phi$1.8-1.9mm) with milky white in color The number of eggs oviposited per clutch was mostly 14. Pre-oviposition period was 25.8 days and mean frequencies of oviposition were 4.4. Female preferred to oviposit on the host plant when available, but oviposited on the artificial leaf successively when the host is not around. On the other hand P. lewisi preferred to suck the nectar of stem or fruit of Phellodendron amurense Ruprecht, Zanthoxylum schinifolium Siebold et zuccarini, Cornus officinalis Siebold et zuccarini and Cornus controversa Hemsley among the 18 plant species tested.

The Effects of Microcurrent Stimulation on Erector Spinae Fatigue Index (미세전류 자극이 척주세움근의 피로지수에 미치는 영향)

  • Kang, Da-Haeng
    • Journal of Digital Convergence
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    • v.11 no.11
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    • pp.545-551
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    • 2013
  • This study aimed to compare the effects of microcurrent stimulation and rest on the fatigue index by applying both to subjects who had accumulated fatigue after performing short-duration physical activity. The experiment was performed at S University from December 2012 to February 2013, on 22 healthy men in their 20s, who were right-handed, and without peripheral or musculoskeletal diseases. All subjects lifted a 10-kg box lift and lower 100 times in 15 minutes. Immediately after that, muscle fatigue index (Median Frequency: MF) and blood fatigue index (Creatine Kinase Lactate: CK, Lactate Dehydrogenase: LDH) were measured by using surface electromyography. The subjects were divided into two groups, and microcurrent stimulation and rest were mediated to the experimental and control groups, respectively, for 20 minutes. After intervention, muscle fatigue index and blood fatigue index were measured and the changes in the accumulated fatigue index were compared. Both groups manifested significantly decreased cumulative fatigue after applying the mediation compared to the pre-intervention level (p < .05), the only exception being the fatigue index of the left erector spinae in the rest group. Compared to the rest group, the microcurrent stimulation group showed a significant decrease in muscle fatigue index (p < .05) but no significant differences were found in the blood fatigue index. Given the results of this study, microcurrent stimulation is considered to be helpful in muscle fatigue recovery for workers who have to perform repetitive movements lifting weights, and additional studies on the correlations of the fatigue recovery with respect to the long-term follow-up of fatigue index and mediation time are necessary.

Detailed Processing and Analysis on the Single-channel Seismic Data for Site Survey of Daecheon-Wonsando Subsea Tunnel (대천-원산도 해저터널 부지조사를 위한 단일채널 탄성파자료의 정밀 처리 및 분석)

  • Kim, Won-Sik;Park, Keun-Pil;Kim, Hyun-Do;Cheong, Snons;Koo, Nam-Hyung;Lee, Ho-Young;Park, Eui-Seob
    • Geophysics and Geophysical Exploration
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    • v.13 no.4
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    • pp.336-348
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    • 2010
  • The Single-channel seismic survey with the source of bubble pulser and drilling survey was carried out in 2008 and 2009 for the site survey of Daecheon-Wonsando area, which was a proposed area of Korea-China subsea tunnel. The goal of this study is to analyze the depth and characteristics of acoustic basement for the stability assessment and tunnel design in this proposed area through combining drilling data with this single-channel seismic data after detailed processing. For this purpose, among the data processing schemes which are usually applied to multi-channel seismic data, we applied the F-K filtering to eliminate the AC(alternating current) noise and the post-stack depth migration to produce depth section. As a result, we verified that the improved depth section could be obtained from single-channel seismic data, and the distribution and characteristics of basement could be analyzed in survey area through the combined analysis with drilling data. However, we could not interpret the detailed structures, fault and fracture zone, due to the quality of bubble pulser source and single-channel data. We expect that those detailed structures can be analyzed when higher resolution seismic data is provided. Therefore, we recommend some items for future seismic survey of subsea tunnel to obtain the high resolution seismic data.