• The Korea Journal of Herbology
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• v.36 no.2
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• pp.1-9
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• 2021

Objectives : Gossypium arboreum (cotton) is traditionally used to treat various health disorders. However, anti-amnesic effect of G. arboreum has not been reported. The objective of this study was to investigate in-vivo the anti-amnesic effects along with in vitro antioxidant and acetylcholinesterase (AChE) inhibition potential in G. arboreum seed essential oil. Methods : The essential oil of G. arboreum obtained by solid phase microextraction (SPME) techniques were identified by gas chromatography-mass spectroscopy (GC-MS). 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay were performed to determine the antioxidant activity at various concentrations (312.5, 625, 1250, 2500, 5000, 10000 ㎍/㎖. Y-maze, passive avoidance and Morris water maze tests were carried out to evaluate improved effect on scopolamine (1 mg/kg)-induced memory dysfunction at the dose level of 50, 100 and 200 mg/kg. Donepezil (5 mg/kg) was used as a positive drug control. We performed acetylcholinesterase (AChE) activity assay in ex vivo. Results : Five volatile compounds were identified in G. arboreum. The assays of DPPH and ABTS revealed that G. arboreum increased antioxidant activity in a dose-dependent manner. G. arboreum ameliorated the percent of spontaneous alternation in the Y-maze test, shortened step-through latency in the passive avoidance test, and increased swimming time in the target zone in the Morris water maze test. In addition, G. arboreum inhibited the AChE activity. Conclusions : Based on these findings, G. arboreum may aid in the prevention and treatment of learning and memory-deficit disorders through antioxidant and AChE inhibitory activities.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.3
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• pp.97-103
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• 2021

Perilla frutescens (P. frutescens) is an important herb used for many purposes such as medicinal, aromatic, and functional food in Asian countries and has beneficial effects such as antioxidant activity, anti-inflammation activity, anti-depression activity, and anxiolytic activity. However, there have been no studies on the protective effect of P. frutescens extract (PFE) on amnesia in vivo. The present study aimed to investigate whether PFE protects memory deficit using a scopolamine-induced mice model and elucidate the underlying mechanisms involved. The protective effect of PFE against scopolamine-induced memory deficits was investigated using Y-maze, passive avoidance, and Morris water maze tests. Furthermore, the potential mechanisms of PFE in improving memory capabilities related to the cholinergic system and antioxidant activity were examined. PFE significantly increased spontaneous alternation in the Y-maze test, step-through latency in the passive avoidance test, and swimming time in the target quadrant in the probe test when compared to the scopolamine-treated group. Likewise, PFE significantly decreased escapes latency in the Morris water maze test. PFE could not regulate cholinergic function in acetylcholine level and acetylcholine esterase activity. However, PFE increased DPPH radical scavenging activity dose-dependently and total polyphenol content was 127.7±1.2 ㎍ GAE/mg. The results showed that the PFE could be a preventive and/or therapeutic candidate for memory and cognitive dysfunction in Alzheimer's disease.

• Convergence Security Journal
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• v.15 no.7
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• pp.39-45
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• 2015

Industrial secrets that companies own recently protected by various act related industrial security such as Trade Secret Act, Act on Prevention of Divulgence and Protection of Industrial Technology, etc. However, despite such protection infringement and leakage accidents of industrial secrets is increasing every year. According to a survey conducted by KAITS(Korean Association for Industrial Technology Security) annual average of estimated damage by industrial secrets leakage is estimated to be "50 trillion won." This is equivalent to the amount of annual revenue of small businesses more than 4,700 units. Following this, industrial secrets leakage causes serious damages to competitiveness of nation and companies and economic. However investment and effort to the industrial secrets leakage crime is lack of level compared to the scale of damage. Actually, most companies except some major companies are lack of response action about industrial secrets leakage because of shortage of separate organization, workforce, budget for industrial secrets leakage security. This paper aims to understand the overall flow of the industrial secrets leakage crime through various taxonomy such as cause of occurrence and leakage pathway and grasp the condition of damage from industrial secrets leakage through analyzation of internal and external industrial secrets leakage crime. This is expected to be the basis for related research.

• Journal of the Korea Convergence Society
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• v.10 no.8
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• pp.105-113
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• 2019

Convergence education, which is operated by many engineering colleges, is mainly led by government-led projects. Convergence majors are established in consideration of the research field of the university professors rather than systematically analyzing the needs of the industry. The purpose of this study is to present the directions of convergence technology education related to new industry fields by analyzing industry needs. Participants were 299 industrial workers in various fields. Instrument consisted of three parts: necessity for convergence education, demand for convergence new technology education from industry perspective, and opinions about undergraduate convergence education. As a result, it was found that the level of awareness of industry needs for fusion technology education was high, and it was confirmed that there is a high demand for IoT convergence, bio-health, advanced new material, and renewable energy fields among convergence technology fields. In addition, the results of the industry demand for convergence new technology education were presented. The suggestions for expectations, problems, and improvements in undergraduate education were presented and implications for convergence technology education were discussed based on the results of the study.

• Journal of the Korea Convergence Society
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• v.7 no.4
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• pp.19-24
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• 2016

To share the informations, we have been used Internet by the unique information transfer method. Many devices are showed and have been used in our various fields because of ICT(Information communication technology) development. The various devices are connected by Internet to send or receive the informations. We call this situation to The Internet of Things(IoT). It use the Internet for the interconnection of the various things. Studies on IoT progress extensively on today. Therefore, we studied a healthcare field related with Internet of things. In this paper, we described many actual cases such as smart bottle of medicine and smart pill in healthcare domains based on IoT.

• Journal of the Korea Convergence Society
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• v.11 no.10
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• pp.219-224
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• 2020

Industrial mixers to homogeneously blend particulate materials have been developed and widely used in various industries. However, most industrial mixers have at most two-degree-of-freedom for the operation, which limits the range of operation parameter selection for optimal blending. This paper proposes a multi-degree-of-freedom robotic mixer designed by converging a conventional drum blender and a robotic manipulator and evaluated its performance in a virtual operating environment. Discrete element simulations were conducted for mixing performance evaluation. The numerical results showed that the proposed mixer design exhibits a better mixing performance than conventional ones.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.5
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• pp.2150-2156
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• 2013

This study attempts to identify how the value network of mobile industry has evolved in the value creating process. The longitudinal case study on SK Telecom was conducted by measuring the SK Telecom's investment structure during from 1999 to 2008. Results show that the convergence services based on the advanced mobile networks changed the revenue structure, and enabled SK Telecom to reposition as a media company. For the value creation, SK Telecom's value network has flexibly adapted to convergence environment through dynamic asset reconfiguration.

• Journal of the Korea Convergence Society
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• v.6 no.6
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• pp.147-152
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• 2015

Eco-friendly or green is a key word which we use in our life. There are examples such as eco-friendly laundry detergent and agricultural products or green car and home, Due to the indiscriminate development, it was caused severe environmental pollution. Green IT is a necessary technology to solve the energy and environmental problems and to increase the productivity of corporations. Therefore, we studied contents related with green IT. The history for green IT has changed from 'Green of IT' to 'IT for Green'. Studies for 'IT for Green' progress extensively on today. In this paper, we described a transition progress and characteristics of green IT. Lastly, we analyzed smart work in the examples of the top.

• Journal of Digital Convergence
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• v.14 no.2
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• pp.141-148
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• 2016

Agricultural machines can be viewed as a very important factor to reduce the workforce and reduce production costs as well as keep up with now days trend caused Labor shortages and the workforce reduction by aging in rural. The latest agricultural machinery has developed into a major agricultural industry to apply and integrate the telecommunication, next-generation batteries, semiconductors, wireless communications, content and high-tech display industry technology with a wide range of applications. In this study, to apply the information and communication technologies on agricultural planters relied on a mechanical method, we designed a quick and sophisticated ICT convergence planters that enable to monitor.

• Journal of the Korean Society of Industry Convergence
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• v.22 no.5
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• pp.475-481
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• 2019

The paradigm of convergence R&D is shifting from the convergence of technologies to the convergence of solutions to solve the complex problems of scientific and social development. On the other hand, it is prevalent that there is a lack of convergence in our research field. Although Korea has invested heavily in fusion research and development, Korea has mainly focused on the application and development of technology, so failed to plan convergence R&D in line with the new paradigm. Therefore, in this study, we searched for convergence R&D area that is being done to solve social problems, and tried to make use of data-driven objective methods. For this purpose, we used the investment information of global R&D projects that had no retrospective properties and derived the convergence R&D area related to coastal flooding.